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    Portsmouth, NH Medical Offices for Lease

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    Versatile Commercial Space on Lafayette Road
    Contact for pricing
    174,240 SF

    Versatile Commercial Space on Lafayette Road

    750 Lafayette Rd, Portsmouth, NH 03801

    Adaptable space suitable for medical, retail, restaurant, or office use.

    • High‑traffic location on Lafayette Rd (Route 1) at a lighted intersection.
    • Adaptable space suitable for medical, retail, restaurant, or office use.
    • Existing infrastructure for medical/dental use, including exam rooms with water.
    • Private and public bathrooms already in place.
    • Potential to connect with adjacent unit for up to 5,650+/- SqFt with two retail frontages.
    Updated: Jul 11, 2025
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    Portsmouth Medical Office Space
    $19 SF/Yr
    55,200 SF

    Portsmouth Medical Office Space

    330 Borthwick Ave, Portsmouth, NH 03801

    Prime Medical Suites, I-95 Access

    • High‑visibility medical office space directly across from Portsmouth Regional Hospital.
    • Ample on‑site parking with accessible spaces.
    • Convenient US Route 1 location with easy I‑95 access.
    • Lease rate: $19.75/SF NNN.
    Updated: Dec 11, 2024
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    Prime Portsmouth Medical Office Space
    $38 SF/Yr
    52,000 SF

    Prime Portsmouth Medical Office Space

    Class A Medical Office Suites Available Now

    360 Corporate Dr, Portsmouth, NH 03801
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    Renovated Office Space For Lease
    $450 / Mo
    165 SF

    Renovated Office Space For Lease

    Newly renovated office condominium in medical park, convenient location.

    230 Lafayette Rd, Portsmouth, NH 03801
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    Office or Medical Office Space
    $16 SF/Yr
    2,027 SF

    Office or Medical Office Space

    Office or medical space in Portsmouth's Pease Tradeport.

    14 Manchester Sq, Portsmouth, NH 03801
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    Based on your search, we've compiled 9 Potential Opportunities for your consideration. Besides 5 Active listings in Portsmouth, NH, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Explore Medical offices for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Seabrook Office: Prime Retail Location
    $16,200 / Mo
    900 SF

    Seabrook Office: Prime Retail Location

    Newly renovated, 900 sq ft office space.

    920 Lafayette Rd, Seabrook, NH 03874
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    Seabrook Office Leasing Opportunity
    Contact for pricing

    Seabrook Office Leasing Opportunity

    Unique office space for lease on high-traffic Route 1.

    920 Lafayette Rd, Seabrook, NH 03874
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    Somersworth Medical Office Space
    $18 SF/Yr
    28,626 SF

    Somersworth Medical Office Space

    28,626 SF Medical Office Building, NH Seacoast

    7 Works Way, Somersworth, NH 03878
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    Somersworth Office Space For Rent
    $14 SF/Yr
    936 SF

    Somersworth Office Space For Rent

    936± SF office space on Route 108 in Somersworth, NH.

    5 Clark Way, Somersworth, NH 03878
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    Portsmouth, NH Medical offices Leasing Opportunities Market Analysis

    Explore Medical offices leasing options in Portsmouth, NH with 5 listings featured on our commercial real estate exchange. The current inventory includes 4,765,115,520 square feet of properties with an estimated lease value of $106 SF/Yr.

    Estimated lease rates for Medical offices in Portsmouth, NH begin at $16 SF/Yr, with an average of $26 SF/Yr and extend to $38 SF/Yr.
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    Browse Medical offices for Lease Near Portsmouth, NH

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    Most Searched ZIP Codes in Portsmouth, NH

    • 03801

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