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    Portsmouth, NH Medical Office Space for Lease

    6 results
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    Versatile Commercial Space on Lafayette Road
    Contact for pricing
    174,240 SF

    Versatile Commercial Space on Lafayette Road

    750 Lafayette Rd, Portsmouth, NH 03801

    Adaptable space suitable for medical, retail, restaurant, or office use.

    • High‑traffic location on Lafayette Rd (Route 1) at a lighted intersection.
    • Adaptable space suitable for medical, retail, restaurant, or office use.
    • Existing infrastructure for medical/dental use, including exam rooms with water.
    • Private and public bathrooms already in place.
    • Potential to connect with adjacent unit for up to 5,650+/- SqFt with two retail frontages.
    Updated: Jul 11, 2025
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    Office or Medical Office Space
    Contact for pricing
    2,027 SF

    Office or Medical Office Space

    14 Manchester Sq, Portsmouth, NH 03801

    Office or medical space in Portsmouth's Pease Tradeport.

    • Zoned for Retail Use: Unique opportunity as the only building at Pease Tradeport with this zoning.
    • Prime Location: Situated in Manchester Square at Pease Tradeport.
    • Suitable for Medical or Office Use: Ideal for outpatient medical groups or traditional office users.
    • Benefits from customer services like the Food Court and EZ Pass.
    • Located amongst other retail businesses.
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    Renovated Office Space For Lease
    Contact for pricing
    165 SF

    Renovated Office Space For Lease

    Newly renovated office condominium in medical park, convenient location.

    230 Lafayette Rd, Portsmouth, NH 03801
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    Prime Portsmouth Medical Office Space
    $38 SF/Yr
    52,000 SF

    Prime Portsmouth Medical Office Space

    Class A Medical Office Suites Available Now

    360 Corporate Dr, Portsmouth, NH 03801
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    Medical Office Space Near Hospital
    Contact for pricing
    1,995 SF

    Medical Office Space Near Hospital

    Medical office suite for lease across from Portsmouth Regional Hospital.

    330 Borthwick Ave, Portsmouth, NH 03801
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    Portsmouth Medical Office Space
    $19 SF/Yr
    55,200 SF

    Portsmouth Medical Office Space

    Prime Medical Suites, I-95 Access

    330 Borthwick Ave, Portsmouth, NH 03801
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    Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 6 Active listings in Portsmouth, NH, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Highly Visible Office/Medical Space
    $15 SF/Yr
    79,404 SF

    Highly Visible Office/Medical Space

    Adaptable office and medical space with high visibility and accessibility.

    118 Portsmouth Ave, Stratham, NH 03885
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    Class A Office Space, Stratham, NH
    $15 SF/Yr
    40,000 SF

    Class A Office Space, Stratham, NH

    Premium Office Suites Available Now

    118 Portsmouth Ave, Stratham, NH 03885
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    Exeter Medical Office Building
    $18 SF/Yr
    80,216 SF

    Exeter Medical Office Building

    Prime Exeter location, multiple suites available.

    1 Hampton Rd, Exeter, NH 03833
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    Medical Building Suites Available
    $18 SF/Yr
    2,590 SF

    Medical Building Suites Available

    Medical suites for rent in premier outpatient building near Exeter Hospital.

    1 Hampton Rd, Exeter, NH 03833
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    Explore Similar Spaces for Sale in Portsmouth, NH

    Consider Similar Space for Sale. We found 1 Spaces in Nearby Locations matching your search parameters.

    Versatile Office Building on Woodbury Avenue
    $575,000
    1,470 SF

    Versatile Office Building on Woodbury Avenue

    1,470 SF office building in high-traffic Portsmouth location.

    1290 Woodbury Ave, Portsmouth, NH 03801
    View details

    Portsmouth, NH Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Portsmouth, NH with 7 listings featured on our commercial real estate exchange. The current inventory includes 4,669,632,000 square feet of properties with an estimated lease value of $57 SF/Yr.

    Estimated lease rates for Medical Office Space in Portsmouth, NH begin at $19 SF/Yr, with an average of $28 SF/Yr and extend to $38 SF/Yr.
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    Browse Medical Office Space for Lease Near Portsmouth, NH

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    Most Searched ZIP Codes in Portsmouth, NH

    • 03801

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