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    Durham, NC
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    Durham, NC Office Buildings for Lease

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    Chapel Hill, NC Raleigh, NC Cary, NC
    22 listings
    CG-Zoned Commercial Space
    $18 SF/Yr
    2,978 SF
    CG-Zoned Commercial Space

    2810 Hillsborough Road, Durham, NC 27705

    High-visibility commercial suite on Hillsborough Road with Commercial General zoning for a broad range of uses.
    • $18/SF/yr lease rate plus TICAM for a 2,978 SF CG‑zoned commercial suite
    • 2,810 Hillsborough Rd sits on a 0.24‑acre parcel on Hillsborough Road in Durham
    • Commercial General (CG) zoning supports a broad range of uses including retail, office, food & beverage, medical, and financial services
    • Located on a high‑traffic corridor connecting Downtown Durham to Duke University
    • Over 181,000 residents within a 5‑mile radius, with population growth projected above 6% through 2030
    Updated: May 18
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    Versatile Building Available for Lease/Sale
    $3,950,000 SF/Yr
    9,790 SF
    Versatile Building Available for Lease/Sale

    211 Rigsbee Ave, Durham, NC 27701

    Adaptable building suitable for restaurant, fitness, or office use.
    • Available for immediate lease or sale.
    • Versatile uses: ideal for restaurants, boutique fitness, and office space.
    • Design and quality of construction.
    • Two front door entries enabling multi‑tenant use.
    • Independent access for multiple tenants.
    Updated: Mar 7
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    Durham Office and Retail Space
    $27 SF/Yr
    16,679 SF
    Durham Office and Retail Space

    Office and retail suites available for lease in Durham.

    404 Hunt Street, Durham, NC 27701

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    Historic Brick Building in Durham
    $33 SF/Yr
    19,931 SF
    Historic Brick Building in Durham

    Historic 91,168 SF brick building in Durham's Warehouse District.

    333 Liggett Street, Durham, NC 27701

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    Office Space Available For Rent
    $34 SF/Yr
    18,502 SF
    Office Space Available For Rent

    Office space for rent with convenient parking and amenities.

    215 Morris Street, Durham, NC 27701

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    Durham Office Space For Rent
    $27 SF/Yr
    51,566 SF
    Durham Office Space For Rent

    Office space for rent with easy access to nearby amenities.

    2510 Meridian Parkway, Durham, NC 27713

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    Durham Office Space For Rent
    $28 SF/Yr
    49,387 SF
    Durham Office Space For Rent

    Prime location with easy access to major transportation routes.

    2605 Meridian Parkway, Durham, NC 27713

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    Durham Office Space For Rent
    $28 SF/Yr
    59,039 SF
    Durham Office Space For Rent

    Office space available in a prime Durham location.

    2525 Meridian Parkway, Durham, NC 27713

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    High-Visibility Office Building
    Contact for pricing
    High-Visibility Office Building

    Prime office location with walkable amenities and major-route access for teams seeking convenience and customer-friendly visibility.

    3917 University Dr, Durham, NC 27707

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    Renovated Office Building Near University
    Contact for pricing
    58,249 SF
    Renovated Office Building Near University

    Three-story office building near mixed-use development with ongoing renovations.

    3710 University Drive, Durham, NC 27707

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    Downtown Durham Mixed-Use Opportunity
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    15,963 SF
    Downtown Durham Mixed-Use Opportunity

    Mixed-use property with retail, office, residential, and parking.

    218 W Morgan Street, Durham, NC 27701

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    Downtown Durham Office Space
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    47,477 SF
    Downtown Durham Office Space

    Centrally located office space in historic Durham tower.

    411 West Chapel Hill Street, Durham, NC 27701

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    Durham Office Building Near University
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    59,650 SF
    Durham Office Building Near University

    59,650 SF office building near mixed-use development.

    3708 Mayfair Street, Durham, NC 27707

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    Office Space Available for Rent
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    10,448 SF
    Office Space Available for Rent

    Office building with 10,448 square feet available for rent.

    410 Blackwell St, Durham, NC 27701

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    Office Space with Extensive Amenities
    Contact for pricing
    298,206 SF
    Office Space with Extensive Amenities

    Office building featuring on-site cafeteria, fitness center, and health clinic.

    42 Moore Drive, Durham, NC 27703

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    Spacious Campus in Durham, NC
    Contact for pricing
    34,041 SF
    Spacious Campus in Durham, NC

    700,000 SF campus with lake and walking trails.

    2810 Meridian Parkway, Durham, NC 27713

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    Downtown Durham Retail/Office Space
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    465,000 SF
    Downtown Durham Retail/Office Space

    Retail and office space available for lease in downtown Durham.

    110 Corcoran Street, Durham, NC 27701

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    Three-Story Office Building For Rent
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    58,249 SF
    Three-Story Office Building For Rent

    58,249 SF office building near University Hill development.

    3710 University Dr, Durham, NC 27707

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    Office Building Near University Hill
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    59,650 SF
    Office Building Near University Hill

    Three-story office building near mixed-use development available for rent.

    3708 Mayfair Street, Durham, NC 27707

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    Class-A Office with Prime Amenities
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    Class-A Office with Prime Amenities

    Landmark 11-story office building with unparalleled signage and amenities.

    4820 Emperor Blvd, Durham, NC 27703

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    Downtown Durham Office Space
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    Downtown Durham Office Space

    Office space for lease in downtown Durham, NC.

    433 W Main St, Durham, NC 27701

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    Class A Office Building
    $30 SF/Yr
    Class A Office Building

    Four-story office building in Imperial Center Business Park.

    4819 Emperor Blvd, Durham, NC 27703

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    Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 22 Active listings in Durham, NC, we suggest exploring alternatives. Similar 13 Properties for Sales.

    Similar Spaces for Sale in Durham, NC

    Consider Similar Space for Sale. We found 13 Spaces matching your search parameters.

    Colonial Square Office/Medical Building
    $3,499,000
    21,532 SF
    Colonial Square Office/Medical Building

    Multi-functional commercial building in Durham's Independence Park.

    4400 Ben Franklin Boulevard, Durham, NC 27704

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    Renovated Office Buildings For Sale
    $2,375,100
    5,220 SF
    Renovated Office Buildings For Sale

    Two renovated office buildings ideal for owner-user or investment.

    2117 Guess Road, Durham, NC 27705

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    Durham, NC Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in Durham, NC with 22 listings featured on our commercial real estate exchange. The current inventory includes 227,872 square feet of properties with an estimated lease value of $3,950,196.

    Estimated lease rates for Office buildings in Durham, NC begin at $18 SF/Yr, with an average of $493,774 and extend to $3,950,000.
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    Most Searched ZIP Codes in Durham, NC

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