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    Durham, NC Office Buildings for Lease

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    Charlotte, NC Raleigh, NC Greensboro, NC
    21 results
    Versatile Building Available for Lease/Sale
    $3,950,000 SF/Yr
    9,790 SF

    Versatile Building Available for Lease/Sale

    211 Rigsbee Ave, Durham, NC 27701

    Adaptable building suitable for restaurant, fitness, or office use.

    • Available for immediate lease or sale.
    • Versatile uses: ideal for restaurants, boutique fitness, and office space.
    • Design and quality of construction.
    • Two front door entries enabling multi‑tenant use.
    • Independent access for multiple tenants.
    Updated: Mar 7
    View details
    Durham Office and Retail Space
    $27 SF/Yr
    16,679 SF

    Durham Office and Retail Space

    404 Hunt Street, Durham, NC 27701

    Office and retail suites available for lease in Durham.

    • Walking distance to numerous restaurants, retail, hotels, entertainment, and housing.
    • Mix of move‑in ready and white box condition suites.
    • Common area conference room, break room, shower room, and mother’s room available.
    • Retail on first floor.
    • Parking ratio is 3 per 1,000 sf (deck parking, additional fee).
    Updated: Mar 7
    View details
    Historic Brick Building in Durham
    $33 SF/Yr
    19,931 SF

    Historic Brick Building in Durham

    Historic 91,168 SF brick building in Durham's Warehouse District.

    333 Liggett Street, Durham, NC 27701
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    Office Space Available For Rent
    $34 SF/Yr
    18,502 SF

    Office Space Available For Rent

    Office space for rent with convenient parking and amenities.

    215 Morris Street, Durham, NC 27701
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    Class A Office Space
    $23 SF/Yr
    79,440 SF

    Class A Office Space

    Class A office space for lease in North Durham.

    4321 Medical Park Dr, Durham, NC 27704
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    Renovated Office Building Near University
    Contact for pricing
    58,249 SF

    Renovated Office Building Near University

    Three-story office building near mixed-use development with ongoing renovations.

    3710 University Drive, Durham, NC 27707
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    Downtown Durham Mixed-Use Opportunity
    Contact for pricing
    15,963 SF

    Downtown Durham Mixed-Use Opportunity

    Mixed-use property with retail, office, residential, and parking.

    218 W Morgan Street, Durham, NC 27701
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    Premier Office Asset in Durham
    Contact for pricing
    105,130 SF

    Premier Office Asset in Durham

    Value-add opportunity in a highly coveted Raleigh-Durham market.

    4505 Emperor Blvd, Durham, NC
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    Durham Office Building Near University
    Contact for pricing
    59,650 SF

    Durham Office Building Near University

    59,650 SF office building near mixed-use development.

    3708 Mayfair Street, Durham, NC 27707
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    Office Space Available for Rent
    Contact for pricing
    10,448 SF

    Office Space Available for Rent

    Office building with 10,448 square feet available for rent.

    410 Blackwell St, Durham, NC 27701
    View details
    Durham Office Space For Rent
    $28 SF/Yr
    49,387 SF

    Durham Office Space For Rent

    Prime location with easy access to major transportation routes.

    2605 Meridian Parkway, Durham, NC 27713
    View details
    Durham Office Space For Rent
    $28 SF/Yr
    59,039 SF

    Durham Office Space For Rent

    Office space available in a prime Durham location.

    2525 Meridian Parkway, Durham, NC 27713
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    Downtown Durham Office Space
    Contact for pricing
    47,477 SF

    Downtown Durham Office Space

    Centrally located office space in historic Durham tower.

    411 West Chapel Hill Street, Durham, NC 27701
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    Downtown Durham Retail/Office Space
    Contact for pricing
    465,000 SF

    Downtown Durham Retail/Office Space

    Retail and office space available for lease in downtown Durham.

    110 Corcoran Street, Durham, NC 27701
    View details
    Office Space with Extensive Amenities
    Contact for pricing
    298,206 SF

    Office Space with Extensive Amenities

    Office building featuring on-site cafeteria, fitness center, and health clinic.

    42 Moore Drive, Durham, NC 27703
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    Class-A Office with Prime Amenities
    Contact for pricing

    Class-A Office with Prime Amenities

    Landmark 11-story office building with unparalleled signage and amenities.

    4820 Emperor Blvd, Durham, NC 27703
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    Three-Story Office Building For Rent
    Contact for pricing
    58,249 SF

    Three-Story Office Building For Rent

    58,249 SF office building near University Hill development.

    3710 University Dr, Durham, NC 27707
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    Office Building Near University Hill
    Contact for pricing
    59,650 SF

    Office Building Near University Hill

    Three-story office building near mixed-use development available for rent.

    3708 Mayfair Street, Durham, NC 27707
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    Downtown Durham Office Space
    Contact for pricing

    Downtown Durham Office Space

    Office space for lease in downtown Durham, NC.

    433 W Main St, Durham, NC 27701
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    Office Building in Imperial Center
    Contact for pricing

    Office Building in Imperial Center

    Three-story office building in Imperial Center Business Park available for rent.

    4307 Emperor Boulevard, Durham, NC 27703
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    Class A Office Building
    Contact for pricing

    Class A Office Building

    Four-story office building in Imperial Center Business Park.

    4819 Emperor Blvd, Durham, NC 27703
    View details
    Based on your search, we've compiled 32 Potential Opportunities for your consideration. Besides 21 Active listings in Durham, NC, we suggest exploring alternatives. Similar 11 Properties for Sales.

    Explore Similar Spaces for Sale in Durham, NC

    Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

    Colonial Square Office/Medical Building
    $3,499,000
    21,532 SF

    Colonial Square Office/Medical Building

    Multi-functional commercial building in Durham's Independence Park.

    4400 Ben Franklin Boulevard, Durham, NC 27704
    View details
    Downtown Durham Redevelopment Opportunity
    $1,000,000

    Downtown Durham Redevelopment Opportunity

    Mixed-use redevelopment opportunity in vibrant Downtown Durham on Main Street.

    113 West Main Street, Durham, NC 27701
    View details
    Imperial Center Office Building For Sale
    Contact for pricing
    105,410 SF

    Imperial Center Office Building For Sale

    Four-story office building in Imperial Center Business Park with modern amenities.

    4819 Emperor Blvd., Durham, NC 27703
    View details

    Durham, NC Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in Durham, NC with 21 listings featured on our commercial real estate exchange. The current inventory includes 252,768 square feet of properties with an estimated lease value of $3,950,174.

    Estimated lease rates for Office buildings in Durham, NC begin at $23 SF/Yr, with an average of $564,310 and extend to $3,950,000.
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    Most Searched ZIP Codes in Durham, NC

    • 27701
    • 27703
    • 27707
    • 27713
    • 27704

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