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    Poplar Bluff, MO Healthcare Properties for Sale

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    Fisk, MO Harviell, MO Wappapello, MO
    Versatile Building in Poplar Bluff
    $325,000
    12,351 SF
    Versatile Building in Poplar Bluff

    338 Hazel St, Poplar Bluff, MO 63901

    12351 SF building suitable for various purposes in Poplar Bluff.
    • Large 12,351 sq ft building suitable for various uses
    • Updated with a new roof over the gym, newer heat and air units, new carpet, and fresh paint
    • Includes a 67x35 sanctuary with loft and a 46x37 gym
    • Features 9 classroom‑sized rooms, 5‑8 office/storage rooms, and 3 restrooms
    • Equipped with 2 working kitchens
    Updated: Jun 10
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    Poplar Bluff Ambulance Base
    $937,500
    Poplar Bluff Ambulance Base

    414 N 5th St, Poplar Bluff, MO 63901

    Mission-critical ambulance base in central Poplar Bluff, Missouri.
    • Mission‑critical ambulance base with exclusive county contract.
    • Attractive NN lease structure shifts CAMs, taxes, insurance, utilities, and routine repairs to the tenant.
    • Strategically located in the center of town with strong visibility and accessibility.
    • Secured by 2% annual rent increases beginning January 1, 2029.
    • Custom facility includes beds, bathrooms, laundry, backup generators, and is HIPPA compliant.
    Updated: Nov 25, 2025
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    Versatile Commercial Building in Poplar Bluff
    $325,000
    12,351 SF
    Versatile Commercial Building in Poplar Bluff

    12,351 SF commercial building suitable for various uses.

    338 Hazel St, Poplar Bluff, MO 63901

    View details
    Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 3 Active listings in Poplar Bluff, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 15 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Ambulatory Surgery Center Investment Opportunity
    $8,050,000
    13,650 SF
    Ambulatory Surgery Center Investment Opportunity

    Single-tenant surgery center near St. Francis Medical Center for sale.

    3241 Percy Drive, Cape Girardeau, MO 63701

    View details
    Medical Facility For Sale
    $369,600
    2,016 SF
    Medical Facility For Sale

    2,016 SF medical facility with minimal landlord obligations.

    1095 Commerce Dr, Kennett, MO

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    Versatile Commercial Building on 1.9 Acres
    $2,900,000
    13,458 SF
    Versatile Commercial Building on 1.9 Acres

    All-brick commercial building with abundant parking and multiple use opportunities.

    1429 N Mount Auburn Road, Cape Girardeau, MO 63701

    View details
    Medic One Facility For Sale
    $369,600
    Medic One Facility For Sale

    NNN leased Medic One facility with minimal landlord obligations.

    1095 Commerce Drive, Kennett, MO 63857

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land in Poplar Bluff
    $399,000
    6.64 Acres
    Commercial Land in Poplar Bluff

    6.64 acres of commercial land ready for development.

    3387 Kanell Boulevard, Poplar Bluff, MO 63901

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    Jonesboro Commercial Land For Sale
    $647,500
    4.66 Acres
    Jonesboro Commercial Land For Sale

    4.665 acre commercial lot zoned C-3 in Jonesboro, Arkansas.

    2123 W Washington, Jonesboro, AR 72401

    View details
    Cherokee Village Land For Sale
    $59,500
    3.56 Acres
    Cherokee Village Land For Sale

    3.56 acres with highway frontage in Cherokee Village, Arkansas.

    Hwy 62-412, Cherokee Village, AR 72529

    View details
    Fulton, KY Commercial Development Site
    $1,150,000
    33.60 Acres
    Fulton, KY Commercial Development Site

    33-acre commercial development site in Fulton, KY, near I-69.

    Myatt Road, Fulton, KY 42041

    View details

    Off-Market Properties in Poplar Bluff, MO

    Consider similar Off-Market properties in Poplar Bluff, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1419 Main St
    HOMES (RETIRED, NURSING)
    2,552 SF Lot: 0.25 Acres
    Value Estimation by Request

    1419 Main St, Poplar Bluff, MO 63901-3840

    View details
    1801 Maud St
    HOMES (RETIRED, NURSING)
    6,185 SF Lot: 1.14 Acres
    Value Estimation by Request

    1801 Maud St, Poplar Bluff, MO 63901-4005

    View details
    1871 Speedway Dr
    HOMES (RETIRED, NURSING)
    3,162 SF Lot: 0.05 Acres
    Value Estimation by Request

    1871 Speedway Dr, Poplar Bluff, MO 63901-8307

    View details
    Debbie Ln
    MEDICAL BUILDING
    2,727 SF Lot: 2.96 Acres
    Value Estimation by Request

    Debbie Ln, Poplar Bluff, MO 63901

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    2000 Shelby Rd
    Restaurants
    9,750 SF Lot: 1.00 Acre
    Value Estimation by Request

    2000 Shelby Rd, Poplar Bluff, MO 63901

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    2620 Westwood Blvd
    HOSPITAL - PRIVATE
    6,068 SF Lot: 17.73 Acres
    Value Estimation by Request

    2620 Westwood Blvd, Poplar Bluff, MO 63901-3396

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    3150 Warrior Ln
    MEDICAL BUILDING
    9,053 SF
    Value Estimation by Request

    3150 Warrior Ln, Poplar Bluff, MO 63901-8686

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    3001 May St
    HOSPITAL - PRIVATE
    36,782 SF Lot: 5.00 Acres
    Value Estimation by Request

    3001 May St, Poplar Bluff, MO 63901-1942

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    2337 Main St
    HOMES (RETIRED, NURSING)
    6,470 SF Lot: 0.90 Acres
    Value Estimation by Request

    2337 Main St, Poplar Bluff, MO 63901-2621

    View details
    2704 Debbie Ln, Unit 2711
    MEDICAL BUILDING
    23,447 SF Lot: 18.81 Acres
    Value Estimation by Request
    Unit 2711

    2704 Debbie Ln, Poplar Bluff, MO 63901-2650

    View details
    2698 Debbie Ln
    MEDICAL BUILDING
    6,606 SF Lot: 3.15 Acres
    Value Estimation by Request

    2698 Debbie Ln, Poplar Bluff, MO 63901-2629

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    County Rd 442
    HOSPITAL - PRIVATE
    42,799 SF Lot: 11.12 Acres
    Value Estimation by Request

    County Rd 442, Poplar Bluff, MO 63901

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    Barron Rd
    HOSPITAL - PRIVATE
    24,382 SF Lot: 3.51 Acres
    Value Estimation by Request

    Barron Rd, Poplar Bluff, MO 63901

    View details
    200 B St
    HOSPITAL - PRIVATE
    10,550 SF Lot: 0.42 Acres
    Value Estimation by Request

    200 B St, Poplar Bluff, MO 63901

    View details
    Poplar Bluff, MO 63901
    MEDICAL BUILDING
    4,460 SF Lot: 3.40 Acres
    Value Estimation by Request

    Poplar Bluff, MO 63901

    View details

    Poplar Bluff, MO Healthcare Properties Investment Opportunities Market Analysis

    Explore 18 healthcare properties for sale in Poplar Bluff, MO, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 24,702 square feet of properties for sale, with an estimated market value of $650,000.

    Sale prices for medical real estate in Poplar Bluff, MO start at $325,000, averaging $325,000, and reaching up to $325,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Medical centers 2
    Assisted living facilities 1
    Rehabilitation centers 1
    Spa & wellness properties 1

    Demographics Overview

    Population 35K
    Population Growth (5Y) -0.6%
    Median Household Income $49,979
    College Educated 11.1%

    High-Yield Neighborhoods for Investment

    Identify Poplar Bluff submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63901 $529.2K

    Total CRE Inventory on Market (SF)

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