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    Poplar Bluff, MO Office Properties & Spaces for Lease

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    Saint Louis, MO Louis, MO Kansas City, MO
    6,500 SF Commercial Space
    $6,000 /Mo

    6,500 SF Commercial Space

    3999 Highway PP Suite 3, Poplar Bluff, MO 63901

    6,500 SF commercial space for lease in Poplar Bluff, MO.

    • Expansive 6,500 sq ft commercial space.
    • Versatile open layout suitable for various businesses.
    • Prime location with ample parking.
    • Previously utilized as a medical rehabilitation facility.
    • Relatively new construction (Year Built: 2012).
    Updated: Oct 15, 2025
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    Prime Retail/Office Space Available
    $1,850 /Mo
    1,862 SF

    Prime Retail/Office Space Available

    1201 Sterling Drive, Poplar Bluff, MO 63901

    Highly visible 1,860 sq ft commercial suite for lease.

    • Prime 1,860 sq ft retail/office space in a sought‑after shopping and office district.
    • High visibility location with steady foot and vehicle traffic.
    • Flexible open floor plan suitable for various businesses (boutique, office, studio).
    • Large display windows for natural light and brand showcasing.
    • Ample parking and easy access to major roads.
    Updated: Oct 14, 2025
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    Small Office Space For Rent
    $500 /Mo

    Small Office Space For Rent

    Office space for rent, utilities included, common waiting area.

    2051 N Westwood Boulevard, Poplar Bluff, MO 63901
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    Prime Retail/Office Space Available
    $143 SF/Yr
    1,860 SF

    Prime Retail/Office Space Available

    Highly visible 1,860 sq ft commercial suite for rent.

    1201 Sterling Drive, Poplar Bluff, Missouri 63901, Poplar Bluff, MO 63901
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    Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 4 Active listings in Poplar Bluff, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

    Explore Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Adaptable Commercial Space in Marmaduke
    $950 /Mo
    1,650 SF

    Adaptable Commercial Space in Marmaduke

    Versatile 1,650 sq ft commercial property for rent.

    100 S 2nd Street, Marmaduke, AR 72443
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    Versatile Commercial Property in Marmaduke
    $950 /Mo
    1,650 SF

    Versatile Commercial Property in Marmaduke

    Adaptable commercial space suitable for various business or investment uses.

    100 S 2nd Street, Marmaduke, AR 72443
    View details
    New Office/Retail Center on Main
    $1,950 /Mo
    2,600 SF

    New Office/Retail Center on Main

    Prime location with excellent traffic and visibility.

    600 N. Main Street, Sikeston, MO 63801
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    Sikeston Medical/Office Space Available
    Contact for pricing

    Sikeston Medical/Office Space Available

    Multi-tenant commercial building near Missouri Delta Medical Center.

    808 E Wakefield Ave, Sikeston, MO 63801
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    Explore Similar Spaces for Sale in Poplar Bluff, MO

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    Westwood Blvd Commercial Opportunity
    $599,500
    5,280 SF

    Westwood Blvd Commercial Opportunity

    Prime commercial building on main thoroughfare with income potential.

    2016 N Westwood Boulevard, Poplar Bluff, MO 63901
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    Turnkey Commercial Space with Warehouses
    $599,000
    4,337 SF

    Turnkey Commercial Space with Warehouses

    Two commercial buildings totaling 7437 SF on 3 acres.

    1401 Black River Industrial Park Road, Poplar Bluff, MO 63901
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    Renovated Commercial Space, High Visibility
    $74,900
    975 SF

    Renovated Commercial Space, High Visibility

    Renovated commercial space with excellent visibility, ideal for various businesses.

    1614 S Broadway Street, Poplar Bluff, MO 63901
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    Versatile Commercial Space in Poplar Bluff
    $299,900
    3,475 SF

    Versatile Commercial Space in Poplar Bluff

    High-traffic location with remodeled space suitable for various business ventures.

    1025 S Westwood Boulevard, Poplar Bluff, MO 63901
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    Live/Work Property Near National Forest
    $220,000
    4,800 SF

    Live/Work Property Near National Forest

    Mixed-use property with shop and living area on 3.78 acres.

    5914 Highway W, Poplar Bluff, MO 63901
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    Former Police Station For Sale
    $499,000
    8,000 SF

    Former Police Station For Sale

    8000 sq ft commercial property in Poplar Bluff, Missouri.

    1111 Poplar Street, Poplar Bluff, MO 63901
    View details
    Prime Retail/Office Center Opportunity
    Contact for pricing
    6,500 SF

    Prime Retail/Office Center Opportunity

    New retail/office center in growing Poplar Bluff location.

    2000 Shelby Road, Poplar Bluff, MO 63901
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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land For Lease
    $12,500 /Mo

    Commercial Land For Lease

    Prime commercial land for lease in high-traffic Rolla location.

    626 Bishop Avenue S, Rolla, MO 65401
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    Commercial Land on Kingshighway
    $5,500 /Mo
    4,000 SF

    Commercial Land on Kingshighway

    Prime commercial land for lease in high-traffic Rolla location.

    1014 Kingshighway Street, Rolla, MO 65401
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    High-Traffic Commercial Land in Rolla
    $7,500 /Mo

    High-Traffic Commercial Land in Rolla

    0.61 acre commercial land in high-traffic area for lease.

    704 N Bishop Avenue, Rolla, MO 65401
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    Cleared Lot in St Clair
    $1.00 SF/Yr

    Cleared Lot in St Clair

    1.5-acre cleared lot zoned for general commercial use.

    Saint Clair, MO 63077
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    Poplar Bluff, MO Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Poplar Bluff, MO with 4 listings featured on our commercial real estate exchange. The current inventory includes 1,447,289,678 square feet of properties with an estimated lease value of $14 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Poplar Bluff, MO begin at $2 SF/Yr, with an average of $7 SF/Yr and extend to $11 SF/Yr.
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    Most Searched ZIP Codes in Poplar Bluff, MO

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