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    Poplar Bluff, MO Commercial Real Estate for Lease

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    Saint Louis, MO Louis, MO Springfield, MO
    11 results
    6,500 SF Commercial Space
    $6,000 /Mo

    6,500 SF Commercial Space

    3999 Highway PP Suite 3, Poplar Bluff, MO 63901

    6,500 SF commercial space for lease in Poplar Bluff, MO.

    • Expansive 6,500 sq ft commercial space.
    • Versatile open layout suitable for various businesses.
    • Prime location with ample parking.
    • Previously utilized as a medical rehabilitation facility.
    • Relatively new construction (Year Built: 2012).
    Updated: Oct 15, 2025
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    Prime Retail/Office Space Available
    $1,850 /Mo
    1,862 SF

    Prime Retail/Office Space Available

    1201 Sterling Drive, Poplar Bluff, MO 63901

    Highly visible 1,860 sq ft commercial suite for lease.

    • Prime 1,860 sq ft retail/office space in a sought‑after shopping and office district.
    • High visibility location with steady foot and vehicle traffic.
    • Flexible open floor plan suitable for various businesses (boutique, office, studio).
    • Large display windows for natural light and brand showcasing.
    • Ample parking and easy access to major roads.
    Updated: Oct 14, 2025
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    Westwood Village Retail Space
    $1,550 /Mo
    18,000 SF

    Westwood Village Retail Space

    Retail space in established Westwood Village Shopping Center.

    2201 Westwood Boulevard N, Poplar Bluff, MO 63901
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    Small Office Space For Rent
    $500 /Mo

    Small Office Space For Rent

    Office space for rent, utilities included, common waiting area.

    2051 N Westwood Boulevard, Poplar Bluff, MO 63901
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    Retail Space in Poplar Bluff
    $22 SF/Yr
    3,630 SF

    Retail Space in Poplar Bluff

    Retail spaces available in a busy shopping center.

    715-797 N Westwood Blvd, Poplar Bluff, MO
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    Valley Plaza Retail Space Available
    $12 SF/Yr

    Valley Plaza Retail Space Available

    Retail spaces for lease in Poplar Bluff's Valley Plaza.

    715-797 N. Westwood Blvd., Poplar Bluff, MO 63901
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    Prime Retail Space Available
    $16 SF/Yr
    3,200 SF

    Prime Retail Space Available

    Retail spaces in high-traffic Poplar Bluff location.

    1915-1935 N Westwood Blvd, Poplar Bluff, MO
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    Retail Space Near Planet Fitness
    Contact for pricing
    27,776 SF

    Retail Space Near Planet Fitness

    27,776 SF retail space in Poplar Bluff's retail corridor.

    952 N. Westwood Blvd., Poplar Bluff, MO 63901
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    Prime Retail/Office Space Available
    $143 SF/Yr
    1,860 SF

    Prime Retail/Office Space Available

    Highly visible 1,860 sq ft commercial suite for rent.

    1201 Sterling Drive, Poplar Bluff, Missouri 63901, Poplar Bluff, MO 63901
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    Retail Space in Poplar Bluff
    $15 SF/Yr
    1,200 SF

    Retail Space in Poplar Bluff

    Retail space available in a busy shopping center.

    1361-1429 N Westwood Blvd, Poplar Bluff, MO
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    Prime Retail Development Land Available
    Contact for pricing

    Prime Retail Development Land Available

    Land for lease in a high-traffic retail development.

    Hwy 67 & Oak Grove Rd, Poplar Bluff, MO
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    Based on your search, we've compiled 58 Potential Opportunities for your consideration. Besides 11 Active listings in Poplar Bluff, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 43 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Adaptable Commercial Space in Marmaduke
    $950 /Mo
    1,650 SF

    Adaptable Commercial Space in Marmaduke

    Versatile 1,650 sq ft commercial property for rent.

    100 S 2nd Street, Marmaduke, AR 72443
    View details
    Versatile Commercial Property in Marmaduke
    $950 /Mo
    1,650 SF

    Versatile Commercial Property in Marmaduke

    Adaptable commercial space suitable for various business or investment uses.

    100 S 2nd Street, Marmaduke, AR 72443
    View details
    New Office/Retail Center on Main
    $1,950 /Mo
    2,600 SF

    New Office/Retail Center on Main

    Prime location with excellent traffic and visibility.

    600 N. Main Street, Sikeston, MO 63801
    View details
    Sikeston Medical/Office Space Available
    Contact for pricing

    Sikeston Medical/Office Space Available

    Multi-tenant commercial building near Missouri Delta Medical Center.

    808 E Wakefield Ave, Sikeston, MO 63801
    View details

    Explore Similar Spaces for Sale in Poplar Bluff, MO

    Consider Similar Space for Sale. We found 43 Spaces matching your search parameters.

    Westwood Blvd Commercial Opportunity
    $599,500
    5,280 SF

    Westwood Blvd Commercial Opportunity

    Prime commercial building on main thoroughfare with income potential.

    2016 N Westwood Boulevard, Poplar Bluff, MO 63901
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    Commercial Building on 3.82 Acres
    $750,000
    4,560 SF

    Commercial Building on 3.82 Acres

    Multi-use building with expansion potential near future Interstate 57.

    140 W Outer Rd., Poplar Bluff, MO 63901
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    Turnkey Commercial Space with Warehouses
    $599,000
    4,337 SF

    Turnkey Commercial Space with Warehouses

    Two commercial buildings totaling 7437 SF on 3 acres.

    1401 Black River Industrial Park Road, Poplar Bluff, MO 63901
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    Renovated Commercial Space, High Visibility
    $74,900
    975 SF

    Renovated Commercial Space, High Visibility

    Renovated commercial space with excellent visibility, ideal for various businesses.

    1614 S Broadway Street, Poplar Bluff, MO 63901
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    Versatile Commercial Space in Poplar Bluff
    $299,900
    3,475 SF

    Versatile Commercial Space in Poplar Bluff

    High-traffic location with remodeled space suitable for various business ventures.

    1025 S Westwood Boulevard, Poplar Bluff, MO 63901
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    Commercial Building with Rental Income
    $399,000
    3,600 SF

    Commercial Building with Rental Income

    3600 sq ft commercial building with three fully rented units.

    1600 W Maud, Poplar Bluff, MO 63901
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    Prime Commercial Building For Sale
    $1,500,000

    Prime Commercial Building For Sale

    Commercial building with four occupied units and highway visibility.

    2000 N Westwood Boulevard, Poplar Bluff, MO 63901
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    Versatile Building in Poplar Bluff
    $325,000
    12,351 SF

    Versatile Building in Poplar Bluff

    12351 SF building suitable for various purposes in Poplar Bluff.

    338 Hazel St, Poplar Bluff, MO 63901
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    Versatile Commercial Property in Poplar Bluff
    $495,000

    Versatile Commercial Property in Poplar Bluff

    Two buildings with income potential in a high-traffic location.

    1029 S Westwood, Poplar Bluff, MO 63901
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    Commercial Land in Poplar Bluff
    $399,000
    6.64 Acres

    Commercial Land in Poplar Bluff

    6.64 acres of commercial land ready for development.

    3387 Kanell Boulevard, Poplar Bluff, MO 63901
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    Income-Producing Commercial Property For Sale
    $285,500

    Income-Producing Commercial Property For Sale

    Commercial property with storage units, office, and residential rental income.

    2710- 2712 Oakmoore Drive, Poplar Bluff, MO 63901
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    Live/Work Property Near National Forest
    $220,000
    4,800 SF

    Live/Work Property Near National Forest

    Mixed-use property with shop and living area on 3.78 acres.

    5914 Highway W, Poplar Bluff, MO 63901
    View details
    Commercial Property in Poplar Bluff
    $1,495,000
    0.72 Acres

    Commercial Property in Poplar Bluff

    Commercial property with high traffic visibility and multiple business opportunities.

    3999 Highway PP, Poplar Bluff, MO 63901
    View details

    Poplar Bluff, MO Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Poplar Bluff, MO with 11 listings featured on our commercial real estate exchange. The current inventory includes 2,686,702,358 square feet of properties with an estimated lease value of $68 SF/Yr.

    Estimated lease rates for Commercial real estate in Poplar Bluff, MO begin at $1.03 SF/Yr, with an average of $11 SF/Yr and extend to $22 SF/Yr.
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    Most Searched ZIP Codes in Poplar Bluff, MO

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