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    San Luis Obispo, CA Medical Offices for Lease

    8 results
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    San Luis Obispo Office Space
    $1.75 SF/Yr
    2,159 SF

    San Luis Obispo Office Space

    735 Tank Farm Rd, San Luis Obispo, CA 93401

    Professional office building near airport with upscale finishes and furnishings.

    • Convenient location near the airport and Marigold Center.
    • First‑level suite with open space plan and multiple rooms (offices, kitchen, storage, workout/training).
    • Upscale finishes and furnishings with great common areas.
    • Custom control HVAC system and fully wired for data and phone.
    • Suitable for medical tenant (previously used as a dental office).
    Updated: Nov 14, 2025
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    Remodeled Office Suite For Rent
    $2,250 / Mo
    930 SF

    Remodeled Office Suite For Rent

    1250 Peach St, San Luis Obispo, CA 93401

    Remodeled office suite with mountain views in Fremont Medical Center.

    • Remodeled suite in the coveted Fremont Medical Center
    • Two offices with separate entrances
    • Deck with views of San Luis Mountain
    • Kitchenette and bathroom included
    • Ample parking available
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    Medical Suite Near Highway 101
    Contact for pricing

    Medical Suite Near Highway 101

    Medical suite available for rent near Highway 101.

    620 California G, San Luis Obispo, CA 93401
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    Class A Office Space Available
    $0.93 SF/Yr
    7,197 SF

    Class A Office Space Available

    Ground floor office suite with upgraded finishes and private patios.

    895 Aerovista Pl, San Luis Obispo, CA 93401
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    Medical Office Space Available
    $1.05 SF/Yr
    1,633 SF

    Medical Office Space Available

    First floor medical office space with examination rooms for rent.

    1288 Morro St, San Luis Obispo, CA 93401
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    Medical Office Near Sierra Vista
    $3 SF/Yr
    1,300 SF

    Medical Office Near Sierra Vista

    Ground floor medical office space available near Sierra Vista Hospital.

    100 Casa St, San Luis Obispo, CA 93405
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    Downtown San Luis Obispo Office Space
    $1.05 SF/Yr
    25 SF

    Downtown San Luis Obispo Office Space

    First floor office suite suitable for medical or professional use.

    990 Pacific St, San Luis Obispo, CA 93401
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    Renovated Medical/Dental Office Space
    $2 SF/Yr
    1,010 SF

    Renovated Medical/Dental Office Space

    Recently renovated medical/dental office space available for immediate occupancy.

    1223 Higuera St, San Luis Obispo, CA 93401
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    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 8 Active listings in San Luis Obispo, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Medical offices for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Class A Medical Office Space
    Contact for pricing
    533 SF

    Class A Medical Office Space

    Premier medical office park with highway visibility in Pismo Beach.

    2 James Way, Pismo Beach, CA 93449
    View details
    Class A Medical Office Space
    Contact for pricing
    1,240 SF

    Class A Medical Office Space

    Premier medical office park with highway visibility in Pismo Beach.

    2 James Way, Pismo Beach, CA 93449
    View details
    Medical Office Space Available
    $2 SF/Yr
    1,877 SF

    Medical Office Space Available

    Medical office condo for rent in established medical hub.

    325 Posada Ln, Templeton, CA 93465
    View details
    Medical Office Condo Near Hospital
    Contact for pricing
    1,272 SF

    Medical Office Condo Near Hospital

    Medical office condo for lease near Twin Cities Hospital.

    1105 Las Tablas Rd, Templeton, CA 93465
    View details

    Explore Similar Spaces for Sale in San Luis Obispo, CA

    Consider Similar Space for Sale. We found 2 Spaces in Nearby Locations matching your search parameters.

    Medical Office Space Available
    $2,830,000

    Medical Office Space Available

    Prime medical office space with high visibility in San Luis Obispo.

    689 Tank Farm Rd, San Luis Obispo, CA 93401
    View details
    Santa Rosa Professional Building For Sale
    $2,175,000

    Santa Rosa Professional Building For Sale

    Two-unit medical/general office building constructed in 1962.

    1338 Santa Rosa St, San Luis Obispo, CA 93401
    View details

    San Luis Obispo, CA Medical offices Leasing Opportunities Market Analysis

    Explore Medical offices leasing options in San Luis Obispo, CA with 10 listings featured on our commercial real estate exchange. The current inventory includes 620,904,240 square feet of properties with an estimated lease value of $39 SF/Yr.

    Estimated lease rates for Medical offices in San Luis Obispo, CA begin at $0.93 SF/Yr, with an average of $5 SF/Yr and extend to $29 SF/Yr.
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    Browse Medical offices for Lease Near San Luis Obispo, CA

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    Most Searched ZIP Codes in San Luis Obispo, CA

    • 93401
    • 93405
    • 93408

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