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    Syracuse, NY Live-work Space for Sale

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    Nedrow, NY Camillus, NY Sentinel Heights, NY
    High-Traffic Mixed-Use Property
    Updated: Nov 28, 2025
    High-Traffic Mixed-Use Property

    1607 W Genesee St, Syracuse, NY 13204

    $297,000
    0.20 AC lot
    High‑traffic location on W. Genesee St.
    Versatile space suitable for various businesses (law, insurance, real estate, medical, beauty, wellness).
    Potential for combined home and office use.
    Located directly across the street from the Brooklyn Pickle.
    Adaptable for diverse uses such as office, salon, spa, or studio.
    View details
    Mixed-Use Building with Dental Practice
    Updated: May 13, 2025
    Mixed-Use Building with Dental Practice

    1500 Grant Blvd and Mayar St, Syracuse, NY

    $185,000
    2,600 sqft · 0.14 AC lot
    Existing dental practice with 5 chairs and treatment rooms
    Includes real estate with 2‑bedroom apartment
    Zoned COM 1
    Equipment Included: Panoramic & intraoral x‑ray machines
    Approx. 2600 sf building with unfinished 3rd floor attic
    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 2 Active listings in Syracuse, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 70 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Mixed-Use Farm Live-Work Property
    Mixed-Use Farm Live-Work Property

    265 Main Street, Delhi, NY 13753

    $429,000
    4,173 sqft · 1.40 AC lot

    Live-work and income potential with greenhouse cultivation, workspaces, and a 3-bedroom apartment on 1.4 acres.

    View details
    East Avenue Mixed-Use Property
    East Avenue Mixed-Use Property

    1700 E Ave, Rochester, NY

    $395,000
    3,056 sqft · 0.18 AC lot

    Fully leased mixed-use property with residence and commercial kitchen.

    View details
    Versatile Property with Auto Zoning
    Versatile Property with Auto Zoning

    2211 & 2215 Clifford Ave, Rochester, NY 14609

    $250,000
    0.10 AC lot

    Mixed-use property with auto sales zoning and revenue potential.

    View details
    Unique Multi-Use Farm Property
    Unique Multi-Use Farm Property

    265 Main Street, Delhi, NY 13753

    $429,000
    1.40 AC lot

    Farm property with greenhouses, workspaces, apartment, and historic charm.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Amherst Development Opportunity
    Prime Amherst Development Opportunity

    220 Meyer Road, Buffalo, NY 14226

    $800,000
    0.65 AC lot

    0.65 acre commercial lot in a high-traffic area.

    View details
    Commercial Land Near Oceola Lake
    Commercial Land Near Oceola Lake

    353 East Main Street, Jefferson Valley, NY 10535

    $295,000

    Commercial land for sale in Jefferson Valley, New York.

    View details
    Versatile Mixed-Use Development Opportunity
    Versatile Mixed-Use Development Opportunity

    1093 Ethan Allen Hwy, Georgia, VT 5468

    $174,900

    Land with approved permits for mixed-use development in Georgia, Vermont.

    View details
    Mixed-Use Property Near Temple
    Mixed-Use Property Near Temple

    1538 W SEYBERT Street, Philadelphia, PA 19121

    $200,000
    0.02 AC lot

    Mixed-use property with business and living space near Temple University.

    View details

    Off-Market Properties in Syracuse, NY

    Consider similar Off-Market properties in Syracuse, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1521 Salina St
    OFFICE/RESIDENTIAL (MIXED USE)

    1521 Salina St, Syracuse, NY 13208-1069

    Value Estimation by Request
    2,886 sqft · 0.23 AC lot
    View details
    1228 State St
    OFFICE/RESIDENTIAL (MIXED USE)

    1228 State St, Syracuse, NY 13202

    Value Estimation by Request
    2,960 sqft · 0.33 AC lot
    View details
    301 Salina S Fayette E St
    OFFICE/RESIDENTIAL (MIXED USE)

    301 Salina S Fayette E St, Syracuse, NY 13202

    $1,540,000
    Estimated value
    41,730 sqft · 0.32 AC lot
    View details
    1409 Milton Ave
    OFFICE/RESIDENTIAL (MIXED USE)

    1409 Milton Ave, Syracuse, NY 13209

    Value Estimation by Request
    4,456 sqft · 0.15 AC lot
    View details
    1100 Oak St Rugby Rd
    OFFICE/RESIDENTIAL (MIXED USE)

    1100 Oak St Rugby Rd, Syracuse, NY 13203

    Value Estimation by Request
    2,688 sqft · 0.11 AC lot
    View details
    412 Un Pl
    OFFICE/RESIDENTIAL (MIXED USE)

    412 Un Pl, Syracuse, NY 13208-2392

    Value Estimation by Request
    2,769 sqft · 0.12 AC lot
    View details
    1917 Ss Ave, Unit 19
    OFFICE/RESIDENTIAL (MIXED USE)

    1917 Ss Ave, Syracuse, NY 13207-2020

    Unit 19
    Value Estimation by Request
    2,040 sqft · 0.12 AC lot
    View details
    914 State St
    OFFICE/RESIDENTIAL (MIXED USE)

    914 State St, Syracuse, NY 13208-2461

    Value Estimation by Request
    4,965 sqft · 0.05 AC lot
    View details
    200 Belden Ave, Unit 204
    OFFICE/RESIDENTIAL (MIXED USE)

    200 Belden Ave, Syracuse, NY 13203-1902

    Unit 204
    $1,010,000
    Estimated value
    15,840 sqft · 0.09 AC lot
    View details
    517 Salina St
    OFFICE/RESIDENTIAL (MIXED USE)

    517 Salina St, Syracuse, NY 13208-2530

    Value Estimation by Request
    4,026 sqft · 0.03 AC lot
    View details
    903 Main St
    OFFICE/RESIDENTIAL (MIXED USE)

    903 Main St, Syracuse, NY 13212-1668

    $3,575,000
    Estimated value
    3,560 sqft · 0.43 AC lot
    View details
    804 Salina St
    OFFICE/RESIDENTIAL (MIXED USE)

    804 Salina St, Syracuse, NY 13208-2513

    Value Estimation by Request
    1,460 sqft · 0.03 AC lot
    View details
    211 Tompkins St
    OFFICE/RESIDENTIAL (MIXED USE)

    211 Tompkins St, Syracuse, NY 13204-2094

    $520,000
    Estimated value
    12,120 sqft · 0.45 AC lot
    View details
    223 Marcellus St
    OFFICE/RESIDENTIAL (MIXED USE)

    223 Marcellus St, Syracuse, NY 13204-2919

    Value Estimation by Request
    1,785 sqft · 0.05 AC lot
    View details
    4914 Seneca Tpke
    OFFICE/RESIDENTIAL (MIXED USE)

    4914 Seneca Tpke, Syracuse, NY 13215-2225

    Value Estimation by Request
    1,650 sqft · 0.52 AC lot
    View details
    1375 Burnet Ave, Unit 81
    OFFICE/RESIDENTIAL (MIXED USE)

    1375 Burnet Ave, Syracuse, NY 13206-3518

    Unit 81
    Value Estimation by Request
    4,146 sqft · 0.09 AC lot
    View details
    2851 Milton Ave
    OFFICE/RESIDENTIAL (MIXED USE)

    2851 Milton Ave, Syracuse, NY 13209-2562

    Value Estimation by Request
    1,488 sqft · 0.13 AC lot
    View details
    1500 Lodi St
    OFFICE/RESIDENTIAL (MIXED USE)

    1500 Lodi St, Syracuse, NY 13208-2666

    Value Estimation by Request
    6,637 sqft · 0.13 AC lot
    View details
    6054 Taft Rd
    OFFICE/RESIDENTIAL (MIXED USE)

    6054 Taft Rd, N Syracuse, NY 13212-3303

    Value Estimation by Request
    1,440 sqft · 4.90 AC lot
    View details
    415 Hawley Ave, Unit 17
    OFFICE/RESIDENTIAL (MIXED USE)

    415 Hawley Ave, Syracuse, NY 13203-2409

    Unit 17
    $535,000
    Estimated value
    4,456 sqft · 0.08 AC lot
    View details
    4305 Genesee St
    OFFICE/RESIDENTIAL (MIXED USE)

    4305 Genesee St, Syracuse, NY 13214-2121

    Value Estimation by Request
    2,700 sqft · 0.46 AC lot
    View details
    103 Galster Ave
    OFFICE/RESIDENTIAL (MIXED USE)

    103 Galster Ave, Syracuse, NY 13206-1901

    Value Estimation by Request
    3,408 sqft · 0.06 AC lot
    View details

    Syracuse, NY Live-Work Space Market Trends and Statistics

    Explore 72 live-work space for sale in Syracuse, NY on our real estate platform. These investment opportunities span a total of 2,600 square feet of properties for sale, with an estimated market value of $185,000.

    Sale prices for live-work properties in Syracuse, NY start at $185,000, averaging $185,000, and reaching up to $185,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 89
    Office buildings 30
    Medical Office Space 16
    Creative space 4
    Coworking space 1

    Demographics Overview

    Population 229K
    Population Growth (5Y) -0.9%
    Median Household Income $59,936
    College Educated 33.4%

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Onondaga County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Onondaga County

    Office

    Residential Income

    Property Size Breakdown

    The majority of commercial real estate listings in Syracuse fall within the 100,000+ square foot range.

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    Popular Searches in Syracuse, NY

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    Most Searched ZIP Codes in Syracuse, NY

    • 13204

    Featured Syracuse Real Estate Agencies

    Realmo connects you with licensed Syracuse CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    SUTTON REAL ESTATE COMPANY LLC
    525 PLUM ST STE 100 Syracuse, NY
    Phone: 13154241111
    CBRE Syracuse
    Syracuse, NY 13204
    www.cbre.us/people-and-offices/affiliate-offices/syracuse
    JF Real Estate
    Syracuse, NY 13202
    www.jfrealestate.com

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