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    Missouri Live-work Space for Lease

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    Free-Standing Work-Live Office Space
    $2,750 / Mo
    20,473 SF

    Free-Standing Work-Live Office Space

    1348 E Cherry St, Springfield, MO 65802

    Work-live office space in the 'Roundtree UCD-D' area.

    • Free‑standing building in Roundtree UCD‑D area, ideal for work/live.
    • UCD‑D zoning permits both working and living environments for almost all professions.
    • 2,516 sf m/l with main floor (1,412sf) and upper floor (1,104sf).
    • Features reception area, conference room, kitchen break‑room, and multiple offices/bedrooms.
    • Expansive wrap‑around front porch with ADA access, large rear deck, and yard.
    Updated: Dec 16, 2025
    View details
    Crossroads Brick Building for Rent
    $3,500 / Mo
    3,000 SF

    Crossroads Brick Building for Rent

    215-217 W 19Th Ter, Kansas City, MO 64108

    Office or warehouse space in the Crossroads Art District.

    • Crossroads location ideal for office or warehouse use.
    • Live/work space suitable for startups and established firms.
    • Enjoy a private balcony with views of Southwest Boulevard and the Crossroads Art District.
    • Brick building construction.
    • Minutes from Downtown Kansas City.
    View details
    Based on your search, we've compiled 41 Potential Opportunities for your consideration. Besides 2 Active listings in Missouri, we suggest exploring alternatives. Similar 39 Properties for Sales.

    Explore Similar Spaces for Sale in Missouri

    Consider Similar Space for Sale. We found 39 Spaces in Nearby Locations matching your search parameters.

    Turnkey Live/Work Opportunity in Warrensburg
    $1,300,000
    3.36 Acres

    Turnkey Live/Work Opportunity in Warrensburg

    Profitable kennel, luxury log cabin, and expansion potential on 3.6 acres.

    1604 E Hale Lake Rd, Warrensburg, MO 64093
    View details
    Historic Route 66 Mixed-Use Property
    $990,000
    11,081 SF

    Historic Route 66 Mixed-Use Property

    Mixed-use property with retail/office space and luxury loft residence.

    524 S Main St, Joplin, MO 64801
    View details
    Route 66 Commercial Opportunity
    $200,000
    1,984 SF

    Route 66 Commercial Opportunity

    Unique commercial space with live-work potential on Route 66.

    1209 W 7Th St, Joplin, MO 64801
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    Highway 42 Commercial/Residential Opportunity
    $374,500
    1.90 Acres

    Highway 42 Commercial/Residential Opportunity

    Live and work property with highway visibility in Brumley, Missouri.

    2001 Highway 42, Brumley, MO 65017
    View details
    Downtown St. Louis Live-Work Treasure
    $800,000
    10,691 SF

    Downtown St. Louis Live-Work Treasure

    Unique 5-story mid-rise perfect for live-work in downtown St. Louis.

    1112 Olive St St, Louis, MO 63101
    View details
    Versatile Commercial Buildings with Vacant Lot
    $279,900
    0.50 Acres

    Versatile Commercial Buildings with Vacant Lot

    Two commercial buildings plus a vacant lot with commercial/residential zoning.

    527 Clinton Ave, Osborn, MO 64474
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    Spacious Multi-Level Warehouse Opportunity
    $120,000
    20,000 SF

    Spacious Multi-Level Warehouse Opportunity

    20,000+ sq ft warehouse with versatile space and potential.

    105 Troutdale Rd, Gravois Mills, MO 65037
    View details
    Unique Mixed-Use Property in Cuba
    $175,000
    2,969 SF

    Unique Mixed-Use Property in Cuba

    Versatile property with residential and commercial potential in Cuba, MO.

    605 E Main Ave, Cuba, MO 65453
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    Farmington Mixed-Use Commercial Property
    $299,900
    3,008 SF

    Farmington Mixed-Use Commercial Property

    2574 SF mixed-use property with detached garage and ample parking.

    210 Hyler Dr, Farmington, MO 63640
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    Live-Work Property in Lincoln, MO
    $299,500
    0.34 Acres

    Live-Work Property in Lincoln, MO

    Versatile commercial property with live-work potential in a desirable location.

    210 E Main St, Lincoln, MO 65338
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    Versatile Live-Work Property in Joplin
    $1,150,000
    5,200 SF

    Versatile Live-Work Property in Joplin

    4,000 sq ft shop with 1,200 sq ft living space.

    4445 E Cypress Rd, Joplin, MO 64801
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    Versatile Commercial Property on Acreage
    $260,000
    3.10 Acres

    Versatile Commercial Property on Acreage

    Well-maintained commercial property with daycare business opportunity on 3.1 acres.

    30391 Highway T, Vienna, MO 65582
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    Unique Maplewood Live/Work Building
    $975,000
    7,672 SF

    Unique Maplewood Live/Work Building

    Unique live/work building in Maplewood with many possibilities.

    3723 Commonwealth Ave, Saint Louis, MO 63143
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    Historic Restored Downtown Building
    $194,500

    Historic Restored Downtown Building

    Fully restored historic building in downtown Cole Camp, Missouri.

    104 E Main St, Cole Camp, MO 65325
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    Mixed-Use Property with Slate Roof
    $195,000
    0.12 Acres

    Mixed-Use Property with Slate Roof

    Mixed-use property with high visibility and investment potential.

    3831 S Grand Blvd St, Louis, MO 63118
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    Historic Building in Cole Camp
    $194,500

    Historic Building in Cole Camp

    Restored historic building with showroom and studio in Cole Camp.

    104 N Maple St, Cole Camp, MO 65325
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    Versatile Commercial Building on Main
    $130,000
    0.52 Acres

    Versatile Commercial Building on Main

    Commercial building with customizable spaces and high visibility location.

    2018 W Main, Sedalia, MO 65301
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    Versatile Trenton Property with Potential
    $99,900
    0.11 Acres

    Versatile Trenton Property with Potential

    Adaptable property suitable for residential, business, or live/work use.

    152 E 8Th St, Trenton, MO 64683
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    Cedar Hill Industrial Space
    $1,799,000
    22,000 SF

    Cedar Hill Industrial Space

    Industrial space with cranes, office, apartment, and expansion potential.

    6585 Progress Pkwy, Cedar Hill, MO 63016
    View details
    Midtown Kansas City Work & Live
    $575,000
    0.16 Acres

    Midtown Kansas City Work & Live

    Commercial Airbnb space with office, approved for short-term rental.

    2547 Brooklyn Ave, Kansas City, MO 64127
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    Renovated Mixed-Use Property, Anderson
    $120,000
    691 SF

    Renovated Mixed-Use Property, Anderson

    Versatile renovated property in downtown Anderson with retail and living space.

    101/103 W Main St, Anderson, MO 64831
    View details
    Mixed-Use Property in Soulard Neighborhood
    Pending
    $380,000
    5,155 SF

    Mixed-Use Property in Soulard Neighborhood

    Mixed-use property with retail, artist, and garage spaces.

    1919 S 12Th St, Louis, MO 63104
    View details

    Missouri Live-work space Leasing Opportunities Market Analysis

    Explore Live-work space leasing options in Missouri with 41 listings featured on our commercial real estate exchange. The current inventory includes 1,022,492,558 square feet of properties with an estimated lease value of $15 SF/Yr.

    Estimated lease rates for Live-work space in Missouri begin at $1.61 SF/Yr, with an average of $7 SF/Yr and extend to $14 SF/Yr.
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