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    Portsmouth, NH Commercial Real Estate for Lease

    86 results
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    Portsmouth
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    Portsmouth

    All-inclusive access to workspace, virtual office and meeting rooms in 505 Montgomery

    170 Commerce Way, Portsmouth, NH 03801
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    Portsmouth Commercial Space For Lease
    $11 SF/Yr
    3,921 SF

    Portsmouth Commercial Space For Lease

    500 Maplewood Ave, Portsmouth, NH 03801

    Commercial space with overhead doors, near Interstate 95.

    • Prime location on Route 1 Bypass, near Portsmouth Traffic Circle and I‑95.
    • Equipped for high‑volume tire shop operation including tire balancer, compressor, tire machine, and truck tire racks.
    • Features four overhead doors.
    • Formerly Hanscom's Truck Stop.
    • Year Built: 1942.
    Updated: Jan 3
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    Retail/Office Space in Portsmouth
    Contact for pricing

    Retail/Office Space in Portsmouth

    33 Deer St, Portsmouth, NH 03801

    Updated retail/office space with patio in Portsmouth's North End.

    • Prime location on desirable Deer Street in Portsmouth's revitalized North End.
    • Newly updated interior with fresh paint and new flooring.
    • Generous patio/outdoor space adjacent to the Sheraton Hotel and Conference Center.
    • One underground parking space included with rent.
    • Rent includes water, sewer, and trash.
    Updated: Mar 3
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    Prime Portsmouth Commercial Space Available
    Contact for pricing
    4,792 SF

    Prime Portsmouth Commercial Space Available

    1,470 SF office/retail space in high-traffic Portsmouth location.

    1290 Woodbury Ave, Portsmouth, NH 03801
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    Downtown Portsmouth Office For Lease
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    Downtown Portsmouth Office For Lease

    Office space for lease in downtown Portsmouth, available immediately.

    159 Middle St, Portsmouth, NH 03801
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    Portsmouth Office Space For Lease
    Contact for pricing
    48,787 SF

    Portsmouth Office Space For Lease

    Versatile office space in Portsmouth, accessible from city or bypass.

    500 Maplewood Ave, Portsmouth, NH 03801
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    Prime Retail Space on Route 1
    Contact for pricing
    61,855 SF

    Prime Retail Space on Route 1

    7,000 SF retail space in high-visibility Portsmouth location.

    2299 Lafayette Rd, Portsmouth, NH 03801
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    Downtown Portsmouth Modern Office Space
    Contact for pricing

    Downtown Portsmouth Modern Office Space

    Modern office space in downtown Portsmouth with parking and amenities.

    299 Hanover St, Portsmouth, NH 03801
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    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    Versatile office space available for lease in Portsmouth, New Hampshire.

    500 Maplewood Ave, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant downtown location.

    10 Vaughan St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant, walkable downtown location.

    10 Vaughan St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suites Available
    Contact for pricing

    Downtown Portsmouth Office Suites Available

    Move-in-ready office suites in a vibrant downtown location.

    10 Vaughan St, Portsmouth, NH 03801
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    Prime Portsmouth Commercial Space Available
    Contact for pricing
    174,240 SF

    Prime Portsmouth Commercial Space Available

    High-traffic location suitable for retail, medical, restaurant, or office use.

    750 Lafayette Rd, Portsmouth, NH 03801
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    Versatile Commercial Space on Lafayette Road
    Contact for pricing
    174,240 SF

    Versatile Commercial Space on Lafayette Road

    Adaptable space suitable for medical, retail, restaurant, or office use.

    750 Lafayette Rd, Portsmouth, NH 03801
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    Professional Office Space For Lease
    Contact for pricing
    1,500 SF

    Professional Office Space For Lease

    Individual offices for healthcare practitioners and therapists in Portsmouth, NH.

    4 Greenleaf Woods Dr, Portsmouth, NH 03801
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    Portsmouth Office Building For Lease
    Contact for pricing

    Portsmouth Office Building For Lease

    Office building for lease with high visibility and signage.

    3201 Lafayette Rd, Portsmouth, NH 03801
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    Downtown Rollinsford Office/Retail Space
    $2,500 / Mo

    Downtown Rollinsford Office/Retail Space

    Office/retail space in historic downtown Rollinsford, near Dover and Somersworth.

    82 Front St, Portsmouth, NH 03869
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    Retail Suites in Rollinsford, NH
    $1,300 / Mo

    Retail Suites in Rollinsford, NH

    Two 1,000 SF retail suites available for lease.

    68-78 Front St, Portsmouth, NH 03869
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    Versatile Studio Space For Lease
    $1,500 / Mo

    Versatile Studio Space For Lease

    Studio/flex space near Pease International Tradeport, Portsmouth, NH.

    282 Corporate Dr, Portsmouth, NH 03801
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    Retail/Office Space For Lease
    $16 SF/Yr
    4,100 SF

    Retail/Office Space For Lease

    Retail/office space with ample parking and convenient highway access.

    72 Mirona Rd, Portsmouth, NH 03801
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    Modern Office Space Available
    $24 SF/Yr
    3,679 SF

    Modern Office Space Available

    Contemporary office space in premier business corridor, available April 2026.

    75 Portsmouth Blvd, Portsmouth, NH 03801
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    Class A Office Space Available
    $18 SF/Yr
    3,172 SF

    Class A Office Space Available

    Class A office space for rent in Portsmouth, NH.

    210 Commerce Way, Portsmouth, NH 03801
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    Storefront Space in Downtown Portsmouth
    $2,500 / Mo

    Storefront Space in Downtown Portsmouth

    Prime commercial space with high foot traffic in downtown Portsmouth.

    168 Fleet St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    $2,000 / Mo

    Downtown Portsmouth Office Space Available

    Professional office space in downtown Portsmouth with parking.

    507 State St, Portsmouth, NH 03801
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    Portsmouth, NH Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Portsmouth, NH with 122 listings featured on our commercial real estate exchange. The current inventory includes 27,681,116,760 square feet of properties with an estimated lease value of $425 /Mo.

    Estimated lease rates for Commercial real estate in Portsmouth, NH begin at $1.00 SF/Yr, with an average of $17 SF/Yr and extend to $38 SF/Yr.
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