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    Portsmouth, NH Mixed-use Properties for Sale

    6 results
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    Mixed-Use Investment in Downtown Portsmouth
    $4,800,000

    Mixed-Use Investment in Downtown Portsmouth

    172 Hanover Street, Portsmouth, NH 03801

    Mixed-use property with income and repositioning potential in vibrant downtown.

    • Mixed‑use property in a highly walkable downtown location with multiple income streams.
    • Established Mexican restaurant (La Carreta) provides stable, in‑place income.
    • Second floor offers value‑add potential for residential units (luxury rentals, owner occupancy, or condos).
    • Ground level offers strong potential for re‑tenanting as restaurant, entertainment, or retail space.
    • Benefits from consistent foot traffic, tourism appeal, and sustained local demand.
    Updated: Mar 2
    View details
    Waterfront Lot Near Downtown Portsmouth
    $1,000,000
    0.41 Acres

    Waterfront Lot Near Downtown Portsmouth

    98 Cornwall Street, Portsmouth, NH 03801

    Waterfront mixed-use property near downtown Portsmouth, offering versatile development opportunities.

    • Prime waterfront location on North Mill Pond with direct water access.
    • Walking distance to downtown Portsmouth.
    • Opportunity to redevelop for luxury living.
    • Large lot size suitable for various development plans.
    • Currently features industrial and office buildings.
    Updated: Sep 18, 2025
    View details
    Mixed-Use Development in Portsmouth, NH
    $5,400,000
    0.20 Acres

    Mixed-Use Development in Portsmouth, NH

    Mixed-use development with retail and luxury residences in Portsmouth.

    266 State Street, Portsmouth, NH 03801
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    Mixed-Use Investment Opportunity
    $4,800,000
    12,780 SF

    Mixed-Use Investment Opportunity

    Mixed-use property with income and growth potential in downtown location.

    165-172 Hanover Street, Portsmouth, NH 3801
    View details
    Historic Portsmouth Mixed-Use Gem
    $3,600,000
    0.11 Acres

    Historic Portsmouth Mixed-Use Gem

    Mixed-use property with commercial space and residential apartments in Portsmouth.

    56 Market Street, Portsmouth, NH 03801
    View details
    Mixed-Use Multi-Tenant Property
    $5,300,000
    12,064 SF

    Mixed-Use Multi-Tenant Property

    Premier mixed-use, multi-tenant property with 12,064 square feet.

    93 -101 Market St, Portsmouth, NH 3801
    View details
    Based on your search, we've compiled 133 Potential Opportunities for your consideration. Besides 6 Active listings in Portsmouth, NH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 119 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Victorian Mixed-Use Property in South Berwick
    $589,900
    3,120 SF

    Victorian Mixed-Use Property in South Berwick

    Mixed-use Victorian with office space and residential unit in downtown.

    49 Portland Street, South Berwick, ME 03908
    View details
    Dover Mixed-Use Opportunity
    $795,000
    4,012 SF

    Dover Mixed-Use Opportunity

    Mixed-use property in growing downtown Dover with off-street parking.

    20-22 Fifth Street, Dover, ME 03820
    View details
    Dover Mixed-Use Redevelopment Opportunity
    $799,000
    0.11 Acres

    Dover Mixed-Use Redevelopment Opportunity

    Four-story corner property in Dover, NH with redevelopment potential.

    9 Chestnut Street, Dover, NH 03820
    View details
    Victorian Mixed-Use Property For Sale
    $589,900
    3,120 SF

    Victorian Mixed-Use Property For Sale

    Mixed-use property with commercial office space and residential unit.

    49 Portland Street, South Berwick, ME 3908
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Kittery Commercial Development Opportunity
    $4,000,000
    5,638 SF

    Kittery Commercial Development Opportunity

    Prime 2-acre parcel with redevelopment potential in Kittery, Maine.

    79 Old Post Road, Kittery, ME 03904
    View details
    Prime Portsmouth Commercial Land Opportunity
    $4,500,000
    4.50 Acres

    Prime Portsmouth Commercial Land Opportunity

    4.5-acre commercial property in Portsmouth's Gateway Zone with highway access.

    3600 Lafayette Street, Portsmouth, NH 03801
    View details
    Route 236 Redevelopment Opportunity
    $975,000
    1,560 SF

    Route 236 Redevelopment Opportunity

    6.89-acre site on Route 236 in Kittery, Maine.

    60-62 Route 236, Kittery, ME 3904
    View details
    Kittery Retail Opportunity on Route 1
    $825,000
    1,757 SF

    Kittery Retail Opportunity on Route 1

    Prime retail location with mixed-use zoning and high visibility.

    429 US-1, Kittery, ME 03904
    View details

    Explore Off-Market Properties in Portsmouth, NH

    Consider similar Off-Market properties in Portsmouth, NH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    359 Marcy St

    359 Marcy St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,481 SF
    Value Estimation by Request
    359 Marcy St, Portsmouth, NH 03801-5208
    View details
    157 Farm Ln

    157 Farm Ln

    OFFICE/RESIDENTIAL (MIXED USE) • 0.42 Acres
    Value Estimation by Request
    157 Farm Ln, Portsmouth, NH 03801-3116
    View details
    113 Market St

    113 Market St

    OFFICE/RESIDENTIAL (MIXED USE) • 6,256 SF
    Value Estimation
    $665,000
    113 Market St, Portsmouth, NH 03801-3703
    View details
    504 Middle St

    504 Middle St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,860 SF
    Value Estimation by Request
    504 Middle St, Portsmouth, NH 03801-5018
    View details
    313 Islington St

    313 Islington St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,330 SF
    Value Estimation by Request
    313 Islington St, Portsmouth, NH 03801-8221
    View details
    123 Market St

    123 Market St

    OFFICE/RESIDENTIAL (MIXED USE) • 8,428 SF
    Value Estimation
    $1,730,000
    123 Market St, Portsmouth, NH 03801-3742
    View details
    58 Washington St

    58 Washington St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,363 SF
    Value Estimation by Request
    58 Washington St, Portsmouth, NH 03801-2044
    View details
    88 Brg St

    88 Brg St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,958 SF
    Value Estimation
    $815,000
    88 Brg St, Portsmouth, NH 03801-3904
    View details
    49 Pleasant St

    49 Pleasant St

    OFFICE/RESIDENTIAL (MIXED USE) • 6,329 SF
    Value Estimation
    $2,465,000
    49 Pleasant St, Portsmouth, NH 03801-4517
    View details
    54 Ct St

    54 Ct St

    OFFICE/RESIDENTIAL (MIXED USE) • 4,998 SF
    Value Estimation
    $1,900,000
    54 Ct St, Portsmouth, NH 03801-4439
    View details
    324 Maplewood Ave

    324 Maplewood Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 1,312 SF
    Value Estimation
    $775,000
    324 Maplewood Ave, Portsmouth, NH 03801-3535
    View details
    95 Daniel St

    95 Daniel St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,392 SF
    Value Estimation
    $1,280,000
    95 Daniel St, Portsmouth, NH 03801-3810
    View details
    140 Edmond Ave

    140 Edmond Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 2,422 SF
    Value Estimation
    $760,000
    140 Edmond Ave, Portsmouth, NH 03801-3562
    View details
    105 Market St

    105 Market St

    OFFICE/RESIDENTIAL (MIXED USE) • 6,460 SF
    Value Estimation
    $2,680,000
    105 Market St, Portsmouth, NH 03801-3703
    View details
    426 Middle St

    426 Middle St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,306 SF
    Value Estimation by Request
    426 Middle St, Portsmouth, NH 03801-5017
    View details
    195 Market St

    195 Market St

    OFFICE/RESIDENTIAL (MIXED USE) • 8,262 SF
    Value Estimation
    $3,925,000
    195 Market St, Portsmouth, NH 03801
    View details
    78 Brg St

    78 Brg St

    OFFICE/RESIDENTIAL (MIXED USE) • 3,405 SF
    Value Estimation
    $1,355,000
    78 Brg St, Portsmouth, NH 03801-3904
    View details
    41 Market St

    41 Market St

    OFFICE/RESIDENTIAL (MIXED USE) • 5,419 SF
    Value Estimation
    $620,000
    41 Market St, Portsmouth, NH 03801-3734
    View details

    Portsmouth, NH Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 125 mixed-use properties for sale in Portsmouth, NH, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 353,706 square feet of properties for sale, with an estimated market value of $35,530,000.

    Sale prices for multi use buildings in Portsmouth, NH start at $225,000, averaging $1,076,666, and reaching up to $5,400,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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