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Cape Girardeau County, MO Hospitality Properties for Sale

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Unique Mixed-Use Property with Treehouse
$885,000
7.44 Acres

Unique Mixed-Use Property with Treehouse

4940 County Road 532, Jackson, MO 63755

Exceptional property with a residence and a remarkable treehouse building.

  • Unique 2,500+ sq. ft. "Treehouse" building with commercial‑style kitchen, bar, and large deck offering significant income‑generating potential.
  • Main house features rustic design elements including wood beams, vaulted pinewood ceilings, and a stone wood‑burning fireplace.
  • Fully finished walk‑out basement with family room, bedroom, bonus rooms, and bathroom.
  • Property includes an existing shop and footings for a 40 x 50 shop.
  • Energy‑efficient wood‑burning stove heats the entire home.
Updated: Apr 4
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Historic Landmark in Downtown Jackson
$669,000
10,000 SF

Historic Landmark in Downtown Jackson

101 W Main Street, Jackson, MO 63755

Landmark building with potential for various commercial uses.

  • Prime corner location on the historic downtown square with unmatched views of the remodeled courthouse.
  • Historic landmark building with architectural details throughout, offering a blend of heritage and modern potential.
  • Multiple potential uses including upscale restaurant, boutique hotel/Airbnb, professional office suites, retail destination, or event center.
  • Former full‑service bank with a large drive‑thru, suitable for a restaurant or unique service concept.
  • Spacious 2nd level with exceptional views and an expansive basement.
Updated: Nov 24, 2025
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Based on your search, we've compiled 7 Potential Opportunities for your consideration. Besides 2 Active listings in Cape Girardeau County, MO, we suggest exploring several alternatives: similar 1 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Land For Sale Jackson, MO
$152,300

Land For Sale Jackson, MO

Land available in Cape Girardeau County, Jackson, Missouri.

Tract 3 Catalpa Lane, Jackson, MO 63755
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Two Acre Building Site
$45,000

Two Acre Building Site

Two acre building site with mature trees and utilities.

16758 Newell Road, Tamms, IL 62988
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Prime Commercial Land For Sale
$607,464
9.36 Acres

Prime Commercial Land For Sale

9.36 acres of commercial land with high traffic visibility.

1 Perryville Boulevard, Perryville, MO 63775
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Recreational Land Near Lake Perry
$90,000
22,215 SF

Recreational Land Near Lake Perry

Half-acre recreational lot with utilities near Lake Perry amenities.

1003 Port Perry Drive, Perryville, MO 63775
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Explore Off-Market Properties in Cape Girardeau County, MO

Consider similar Off-Market properties in Cape Girardeau County, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

2070 Sprigg St

2070 Sprigg St

Multifamily properties • 248,038 SF
Value Estimation by Request
2070 Sprigg St, Cape Girardeau, MO 63701
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Cape Girardeau County, MO Hospitality Properties Investment Opportunities Market Analysis

Explore 3 hospitality properties for sale in Cape Girardeau County, MO on our real estate platform. These investment opportunities span a total of 10,000 square feet of properties for sale, with an estimated market value of $669,000.

Sale prices for hospitality properties in Cape Girardeau County, MO start at $669,000, averaging $669,000, and reaching up to $669,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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