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    Holyoke, MA Healthcare Properties for Sale

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    Two-Building Campus on 8.19 Acres
    $2,290,000
    38,286 SF

    Two-Building Campus on 8.19 Acres

    1365-1375 Northampton Street, Holyoke, MA 1040

    Two-building campus on 8.19 acres near Interstate 91.

    • Two‑building campus with 44 rooms and 38 living quarters for diverse usage.
    • Located on 8.19 acres of private, nicely landscaped grounds.
    • Conveniently situated on Route 5, just 0.7 miles from Interstate 91 (Exit 15A), and on the PVTA bus route.
    • Ample on‑site parking available for 40+\/- vehicles.
    • Building 1 features 16 bedrooms, a chapel/meeting room, and multiple living spaces.
    Updated: Nov 21, 2025
    View details
    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 1 Active listings in Holyoke, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 11 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Prime Commercial Lot Near I-84
    $400,000
    3.00 Acres

    Prime Commercial Lot Near I-84

    3-acre commercial lot near I-84 with many permitted uses.

    317 Merrow Road, Tolland, CT 06084
    View details
    Turn-Key Sports and Fitness Facility
    $7,200,000
    141,341 SF

    Turn-Key Sports and Fitness Facility

    Fully operating sports and fitness facility on 17.35 acres.

    100 Gerber Dr, Tolland, CT 6084
    View details
    Former Nursing Facility on 14.7 Acres
    $1,795,000
    49,126 SF

    Former Nursing Facility on 14.7 Acres

    Redevelopment opportunity: former skilled nursing facility on 14.7 acres.

    565 Vernon St, Manchester, CT
    View details
    Prime Land in Buckland Hills
    Contact for pricing
    6,084 SF

    Prime Land in Buckland Hills

    3.44 acre parcel in thriving retail corridor.

    170 Hale Rd, Manchester, CT 6042
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    80+ Acre Development Opportunity
    $1,550,000
    83.12 Acres

    80+ Acre Development Opportunity

    Large residential development land with easy highway access.

    Tolland Stage Road, Tolland, CT 06084
    View details
    80+ Acres Raw Land
    $1,550,000
    83.12 Acres

    80+ Acres Raw Land

    80+ acres of raw land with development potential.

    Tolland Stage Road, Tolland, CT 06084
    View details
    Farmington Commercial Land Opportunity
    $1,000,000
    2,814 SF

    Farmington Commercial Land Opportunity

    2.5 acre lot with potential for commercial development.

    29 Batterson Park Road, Farmington, CT 06032
    View details
    Commercial Land Opportunity in Wynantskill
    $325,000
    7.00 Acres

    Commercial Land Opportunity in Wynantskill

    7 acres of commercial land with frontage on Main Ave.

    453 Main Avenue, Wynantskill, NY 12198
    View details

    Explore Off-Market Properties in Holyoke, MA

    Consider similar Off-Market properties in Holyoke, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    35 Holy Family Rd

    35 Holy Family Rd

    HOMES (RETIRED, NURSING) • 61,085 SF
    Value Estimation
    $2,065,000
    35 Holy Family Rd, Holyoke, MA 01040-2701
    View details
    282 Cabot St

    282 Cabot St

    HOMES (RETIRED, NURSING) • 45,120 SF
    Value Estimation by Request
    282 Cabot St, Holyoke, MA 01040-3141
    View details
    279 Cabot St

    279 Cabot St

    HOMES (RETIRED, NURSING) • 17,435 SF
    Value Estimation by Request
    279 Cabot St, Holyoke, MA 01040-3139
    View details
    260 Easthampton Rd

    260 Easthampton Rd

    HOMES (RETIRED, NURSING) • 57,168 SF
    Value Estimation
    $795,000
    260 Easthampton Rd, Holyoke, MA 01040-1213
    View details
    98 Lower Westfield Rd

    98 Lower Westfield Rd

    Individual retail properties • 38,000 SF
    Value Estimation by Request
    98 Lower Westfield Rd, Holyoke, MA 01040
    View details
    293-299 Clemente St

    293-299 Clemente St

    Office Units
    Value Estimation by Request
    293-299 Clemente St, Holyoke, MA 01040
    View details
    293-299 Clemente St

    293-299 Clemente St

    Office Units
    Value Estimation by Request
    293-299 Clemente St, Holyoke, MA 01040
    View details
    254 Westfield Rd

    254 Westfield Rd

    Individual retail properties • 23,000 SF
    Value Estimation by Request
    254 Westfield Rd, Holyoke, MA 01040
    View details
    98 Lower Westfield Rd

    98 Lower Westfield Rd

    Medical Office Space • 38,000 SF
    Value Estimation by Request
    98 Lower Westfield Rd, Holyoke, MA 01040
    View details
    45 Lowr Westfield Rd

    45 Lowr Westfield Rd

    HOMES (RETIRED, NURSING) • 135,552 SF
    Value Estimation
    $2,305,000
    45 Lowr Westfield Rd, Holyoke, MA 01040-2747
    View details
    36 Lowr Westfield Rd

    36 Lowr Westfield Rd

    HOMES (RETIRED, NURSING) • 110,553 SF
    Value Estimation
    $1,005,000
    36 Lowr Westfield Rd, Holyoke, MA 01040-2749
    View details

    Holyoke, MA Healthcare Properties Investment Opportunities Market Analysis

    Explore 12 healthcare properties for sale in Holyoke, MA on our real estate platform. These investment opportunities span a total of 274,981 square feet of properties for sale, with an estimated market value of $5,580,000.

    Sale prices for medical real estate in Holyoke, MA start at $545,000, averaging $1,860,000, and reaching up to $2,895,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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