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    Holyoke, MA

    Holyoke, MA Commercial Real Estate for Lease

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    35 properties
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    Three-Story Mixed-Use Building
    Updated: Jun 30, 2025
    Three-Story Mixed-Use Building

    107 Lyman St, Holyoke, MA 01040

    $10 SF/Yr
    17,990 sqft
    17,990‑square‑foot, three‑story mixed‑use building
    Planned major remodel allows space customization during renovation
    Office, warehouse, and light‑industrial zoning
    Heat and water included with an on‑site dumpster
    Flexible gross lease terms available
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    Connected Office Units
    Updated: Aug 30
    Connected Office Units

    176 High St, Holyoke, MA 01040

    $1,250-$2,500/Mo
    2,000 sqft
    Two connected suites, each approximately 1,000 square feet
    Located at 176 & 178 High Street in Downtown Holyoke
    Reception areas, private offices, and conference/work areas
    ADA‑accessible entrance and strong High Street visibility
    Suites may be leased separately or together
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    Ground-Floor Retail Corner Suite
    Ground-Floor Retail Corner Suite

    226-230 Sargeant St, Holyoke, MA 01040

    $22 SF/Yr
    1,012 sqft

    Ground-floor retail unit with expansive corner windows, open layout, and updated utilities in a street-level storefront setting.

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    Three-Story Mixed-Use Building
    Three-Story Mixed-Use Building

    107 Lyman St, Holyoke, MA 01040

    $10 SF/Yr
    17,990 sqft

    Remodeled commercial space supports office, warehouse, and light industrial uses with heat, water, and dumpster service included.

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    Freestanding Downtown Office Building
    Freestanding Downtown Office Building

    15A Main Street, Holyoke, MA 01040

    $6,200/Mo

    Recently renovated two-floor office with private offices, open areas, conference room, and break room.

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    Connected Office Suites
    Connected Office Suites

    178 High Street, Holyoke, MA 01040

    $1,250/Mo

    Two bright commercial suites offer reception, private offices, conference areas, and ADA access.

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    Small Flex Space For Rent
    Small Flex Space For Rent

    68 Winter St, Holyoke, MA 01040

    $480/Mo
    400 sqft 0.33 AC lot

    400 sqft flex space suitable for artists and entrepreneurs.

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    Office Building with Professional Potential
    Office Building with Professional Potential

    302-322 High St, Holyoke, MA 01040

    Contact for pricing
    5,600 sqft

    Office building totaling 5,600 SF, available for lease and suited to light medical or other professional uses.

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    First-Floor Former Bank Branch Office
    First-Floor Former Bank Branch Office

    302-322 High St, Holyoke, MA 01040

    Contact for pricing
    5,570 sqft

    First-floor space, formerly a bank branch, suitable for office or potential retail use.

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    Upper-Level Renovated Office Suite
    Upper-Level Renovated Office Suite

    306 Race Street, Holyoke, MA 01040

    $20 SF/Yr

    Renovated upper-floor office suite with private offices, reception, break room, private bath, and large windows.

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    Manufacturing Facility with Heavy Power
    Manufacturing Facility with Heavy Power

    111 Mosher Street, Holyoke, MA 01040

    Contact for pricing
    110,800 sqft 7.61 AC lot

    Industrial-zoned facility with distributed electrical capacity, loading infrastructure, trailer parking, and outdoor storage allowance.

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    Industrial Warehouse with Bridge Crane
    Industrial Warehouse with Bridge Crane

    373 Whitney Ave, Holyoke, MA 01040

    Contact for pricing
    45,011 sqft 6.75 AC lot

    Warehouse with 14 to 16 clear height, wet sprinkler system, and 500 LB bridge crane, plus dock and drive-in access.

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    Fenced Commercial Land
    Fenced Commercial Land

    162 - 166 Elm St, Holyoke, MA 01040

    $500/Mo

    Vacant outdoor site with BH zoning and immediate availability for approved commercial uses.

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    Holyoke Basement Retail Space Available
    Holyoke Basement Retail Space Available

    301 High St, Holyoke, MA 01040

    $2,500/Mo

    4,000 SF basement space for creative vision in Holyoke.

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    Ingleside Professional Center Office Suite
    Ingleside Professional Center Office Suite

    40 Bobala Rd, Holyoke, MA 01040

    $20 SF/Yr
    3,750 sqft 5.18 AC lot

    First floor office/medical suite for lease near I-91.

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    Medical Office Space with Build-to-Suit
    Medical Office Space with Build-to-Suit

    245 High Street, Holyoke, MA 01040

    $18 SF/Yr

    Flexible multi-floor medical and professional office space directly connected to Holyoke Health Center, with nearby public parking.

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    Retail Space in Holyoke Center
    Retail Space in Holyoke Center

    2203-2295 Northampton St, Holyoke, MA

    Contact for pricing
    3,000 sqft 58.36 AC lot

    Retail space available in a busy Holyoke shopping center.

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    Versatile Warehouse and Studio Spaces
    Versatile Warehouse and Studio Spaces

    420 Race Street, Holyoke, MA 01040

    Contact for pricing
    23,432 sqft

    Adaptable warehouse and studio spaces available for rent in Holyoke.

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    Mixed-Use Office and Retail Suites
    Mixed-Use Office and Retail Suites

    287-289 High Street, Holyoke, MA 01040

    $12 SF/Yr

    Flexible office and retail suites are available with full ADA accessibility and elevator service in a multi-tenant downtown setting.

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    Downtown Commercial Space For Rent
    Downtown Commercial Space For Rent

    195 High St, Holyoke, MA 01040

    $1,500/Mo

    Ground level commercial space in downtown location, ready to lease.

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    Multi-Suite Retail Storefront
    Multi-Suite Retail Storefront

    98 Suffolk St, Holyoke, MA 01040

    Contact for pricing

    Five commercially zoned suites offer flexible layouts for a range of retail configurations.

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    Holyoke Flex Space For Rent
    Holyoke Flex Space For Rent

    81 Sargeant St, Holyoke, MA 01040

    $12 SF/Yr

    Flexible industrial, creative, and office spaces available for rent.

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    Warehouse/Flex Building with Highway Access
    Warehouse/Flex Building with Highway Access

    158 Chestnut St, Holyoke, MA 01040

    $6 SF/Yr

    Warehouse/flex building for lease with planned improvements and highway access.

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    Industrial Manufacturing Warehouse
    Industrial Manufacturing Warehouse

    110 Winter St, Holyoke, MA 01040

    Contact for pricing
    14,700 sqft

    44,700 SF industrial facility with warehouse space, 2,000 lb freight elevator, and convenient loading docks for manufacturing use.

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    Holyoke, MA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Holyoke, MA with 35 listings featured on our commercial real estate exchange. The current inventory includes 402,095 square feet of properties with an estimated lease value of $180.38.

    Estimated lease rates for Commercial real estate in Holyoke, MA begin at $6 SF/Yr, with an average of $13.88 SF/Yr and extend to $22 SF/Yr.
    Holyoke, MA CRE market trends — vacancy, lease rates and price per SF, updated monthly
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