Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Lancaster, SC Commercial Real Estate for Sale

    171 results
    List
    Map
    Versatile Land on Charlotte Highway
    $1,500,000
    5.61 Acres

    Versatile Land on Charlotte Highway

    Charlotte Hwy, Lancaster, SC 29707

    5.61-acre wooded property with residential and commercial potential.

    • 5.61‑acre wooded property with residential and unimproved commercial potential.
    • Prime location on the corner of 521 and Henry Harris, with road frontage on a 4‑lane state highway, offering excellent visibility and convenient access.
    • Future land use map indicates potential for Commercial Zoning (as of 9/26/25) with Design and Environmental guidelines.
    • County Water available on 521 (tap fee required).
    • Subdivision possible (up to 3 lots due to moratorium).
    Updated: Mar 4
    View details
    Prime Land on Highway 521
    $2,500,000
    3.96 Acres

    Prime Land on Highway 521

    6993 Charlotte Hwy, Lancaster, SC 29707

    3.96 acres ideal for commercial or residential development.

    • Prime location on Highway 521 in a fast‑growing area, ideal for commercial development, mixed‑use projects, residential use, or an event venue.
    • Significant future potential for commercial zoning (as of 9/26/25) based on Lancaster County UDO future land use map.
    • Combined acreage of 3.96, offering ample space for various development opportunities.
    • Located close to shopping, dining, schools, and other conveniences.
    • Potential for subdivision into up to 3 parcels under the Lancaster County 9‑month moratorium.
    Updated: Mar 3
    View details
    Commercial Lot on Highway S 200
    $69,000
    0.50 Acres

    Commercial Lot on Highway S 200

    Prime commercial lot with high visibility and utilities connected.

    2067 Great Falls Hwy, Lancaster, SC 29720
    View details
    Commercial Lot on Highway S 200
    $69,900
    0.50 Acres

    Commercial Lot on Highway S 200

    Prime commercial lot with high visibility and utilities access.

    2067 Great Falls Hwy, Lancaster, SC 29720
    View details
    Lancaster Commercial Opportunity For Sale
    $279,000
    0.57 Acres

    Lancaster Commercial Opportunity For Sale

    General Business zoned land in high-traffic Lancaster location.

    2537 Charlotte Hwy, Lancaster, SC 29720
    View details
    Commercial Land in Lancaster, SC
    $75,000
    0.28 Acres

    Commercial Land in Lancaster, SC

    Prime commercial land with high visibility and easy access.

    E Arch St, Lancaster, SC 29720
    View details
    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres

    Two Professional Buildings Near MUSC

    Two professional office buildings near MUSC in Lancaster, South Carolina.

    1201 Colonial Cmns Ct, Lancaster, SC 29720
    View details
    Prime Development Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Development Land on Charlotte Highway

    Development opportunity on a high-traffic corridor near residential developments.

    2383 Charlotte Hwy, Lancaster, SC 29720
    View details
    Commercial Land in Lancaster, SC
    $149,900
    0.47 Acres

    Commercial Land in Lancaster, SC

    Commercial land suitable for various business ventures.

    2836 Lynwood Dr, Lancaster, SC 29720
    View details
    Commercial Land on Highway 200
    $392,000
    3.14 Acres

    Commercial Land on Highway 200

    3.14 acre commercial land with road frontage and utilities.

    Hwy 200 Byp, Lancaster, SC 29720
    View details
    Commercial Land on Corner Lot
    $272,500
    1.81 Acres

    Commercial Land on Corner Lot

    Corner lot commercial land with road frontage and utilities.

    S Main St, Lancaster, SC 29720
    View details
    38 Acres in Lancaster, SC
    $2,100,000
    38.00 Acres

    38 Acres in Lancaster, SC

    38-acre property suitable for redevelopment, subdivision, or private residence.

    9504 Van Wyck Rd, Lancaster, SC 29720
    View details
    Land For Sale, Lancaster SC
    $75,000
    0.47 Acres

    Land For Sale, Lancaster SC

    Commercial land available in Lancaster, South Carolina.

    10129 Lake Shore Dr, Lancaster, SC 29720
    View details
    Prime Commercial Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Commercial Land on Charlotte Highway

    15.55 acres with high traffic and development potential.

    2383 Charlotte Hwy, Lancaster, SC 29720
    View details
    Lancaster, SC Land For Sale
    $55,000
    0.57 Acres

    Lancaster, SC Land For Sale

    Commercial land available in Lancaster, South Carolina.

    Airport Rd, Lancaster, SC 29720
    View details
    Lancaster Land For Sale
    $115,000
    11.66 Acres

    Lancaster Land For Sale

    11.66 acres of wooded property in downtown Lancaster, SC.

    Woodland Dr, Lancaster, SC 29720
    View details
    Lancaster Land with Highway Frontage
    $1,600,000
    25.00 Acres

    Lancaster Land with Highway Frontage

    25 acres of land ideal for development or investment.

    3080 Charlotte Hwy, Lancaster, SC 29720
    View details
    Lancaster Farmland with Barn
    $799,900
    39.80 Acres

    Lancaster Farmland with Barn

    39.8 acres of rolling farmland with barn and ponds.

    992 S Potter Rd, Lancaster, SC 29720
    View details
    Land for Varied Farming, Recreation
    $400,000
    44.60 Acres

    Land for Varied Farming, Recreation

    44.602 acre lot ideal for farming and recreation.

    Daystar Rd, Lancaster, SC 29720
    View details
    Secluded Land with Creek Border
    $650,000
    77.99 Acres

    Secluded Land with Creek Border

    77+ acre lot perfect for recreation and residential use.

    Daystar Rd, Lancaster, SC 29720
    View details
    Lancaster, SC Turnkey Acreage
    Pending
    $997,000
    196.93 Acres

    Lancaster, SC Turnkey Acreage

    196+/- acres in Lancaster, SC, ideal for recreation or homestead.

    Green Rd, Lancaster, SC 29720
    View details
    Lancaster County Acreage with Development Potential
    $2,775,000
    84.67 Acres

    Lancaster County Acreage with Development Potential

    84.67 acres in Lancaster County ideal for various uses.

    1049 Culp Ferguson Rd, Lancaster, SC 29720
    View details
    Lancaster Land for Varied Use
    $150,000
    6.19 Acres

    Lancaster Land for Varied Use

    Land for residential, farming, hunting, and recreational use.

    Daystar Rd, Lancaster, SC 29720
    View details
    Protected Timberland Tract in Lancaster
    $1,332,500
    533.00 Acres

    Protected Timberland Tract in Lancaster

    533-acre recreational timberland tract near Lancaster, South Carolina.

    Duckwood Rd, Lancaster, SC 29720
    View details

    Lancaster, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 71 commercial real estate for sale in Lancaster, SC, showcased through 171 active listings on our real estate platform. These investment opportunities span a total of 60,296,536 square feet of properties for sale, with an estimated market value of $44,504,600.

    Sale prices for business properties in Lancaster, SC start at $55,000, averaging $1,141,143, and reaching up to $6,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Commercial real estate for Sale Near Lancaster, SC

    Popular Searches in Lancaster, SC

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!