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Mt Pleasant, SC

Mt Pleasant, SC Commercial Real Estate for Lease

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Isle Of Palms, SC Charleston, SC Sullivans Island, SC Wando, SC North Charleston, SC Hanahan, SC Johns Island, SC Goose Creek, SC

101 properties

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Furnished Executive Corner Office

Updated: Jul 13

Furnished Executive Corner Office

10 Shem Drive 100-E, Mount Pleasant, SC 29464

$136 SF/Yr

Year built 2021 executive office space in the Coleman Blvd. business district
Office E is an approximately 11' x 10' corner office with multiple windows
Offered at $1,250 per month on a full‑service executive office sublease
Lease includes all utilities and high‑speed internet
Includes on‑site parking plus access to a shared conference room, shared kitchenette, and shared main lobby

Furnished Executive Office Suite

Updated: Jul 13

Furnished Executive Office Suite

10 Shem Drive 100-C, Mount Pleasant, SC 29464

$177 SF/Yr

Class A furnished executive office built in 2021 in the Coleman Blvd. business district
Office C with a window offers approximately 11' x 6' workspace
Lease at $975/month includes all utilities and high‑speed internet access
Full‑service lease includes on‑site parking plus access to a shared conference room, shared kitchenette, and shared main lobby
Private office has 9‑foot ceilings; main lobby has 11‑foot ceilings

Retail Storefront Property

Retail Storefront Property

627 Hwy 17 N, Mount Pleasant, SC 29466

$32 SF/Yr

For rent retail storefront on a major highway with a sizable 9.01-acre lot for flexible site planning.

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Class A Medical Office Building

Class A Medical Office Building

1280 Hospital Dr, Mt Pleasant, SC 29464

$2,582/Mo

2,582 sqft

Class A medical office building offers a covered patient entry and abundant surface parking.

Medical Office Suites with Ample Parking

Medical Office Suites with Ample Parking

1300 Hospital Dr, Mt Pleasant, SC 29464

$1,757/Mo

3,425 sqft

Three-story medical office building offers suites for lease with ample on-site paved parking.

Retail Space in Mt. Pleasant

Retail Space in Mt. Pleasant

2700 Brickyard Parkway, Mount Pleasant, SC 29466

$28 SF/Yr

3,689 sqft

Retail space for lease in The Shoppes at Brickyard.

Mount Pleasant Retail/Office/Medical Space

Mount Pleasant Retail/Office/Medical Space

1123 Queensborough Boulevard, Mount Pleasant, SC 29464

$30 SF/Yr

3,949 sqft

3,949 SF space ideal for retail, office, or medical.

Class A Flex Space Available

Class A Flex Space Available

547 Long Point Road, Mount Pleasant, SC 29464

$20 SF/Yr

4,380 sqft

Flex space with showroom/office and warehouse, convenient location.

Mount Pleasant Retail Space Available

Mount Pleasant Retail Space Available

543 Long Point Road, Mount Pleasant, SC 29464

$24 SF/Yr

5,250 sqft

Retail space in prime Mount Pleasant location, available June 1, 2026.

Class A Medical Office Building

Class A Medical Office Building

1200 Innovation Way, Mount Pleasant, SC 29466

$28 SF/Yr

14,084 sqft

Renovated medical/office building with ample parking in Mt. Pleasant.

Mount Pleasant Office Space Available

Mount Pleasant Office Space Available

1671 Belle Isle Avenue, Mount Pleasant, SC 29464

$26 SF/Yr

2,227 sqft

Office space available for lease in Mount Pleasant, SC.

Flexible Offices and Coworking at Gregorie Ferry Landing. Contact us today to book a tour!

Flexible Offices and Coworking at Gregorie Ferry Landing. Contact us today to book a tour!

1240 Winnowing Way, Unit 100, Mount Pleasant, SC 29466

16 available spaces from 11 to 2,149 sqft

$129-$23,661/Mo

Flexible workspace in Gregorie Ferry Landing. Book a tour & get info

Medical Office in Mt. Pleasant

Medical Office in Mt. Pleasant

1300 Hospital Dr, Mount Pleasant, SC 29464

$34 SF/Yr

60,809 sqft

Medical office space available for sublease in Mt. Pleasant.

Mount Pleasant Office Space Available

Mount Pleasant Office Space Available

880 Johnnie Dodds Boulevard, Mount Pleasant, SC 29464

$28 SF/Yr

2,400 sqft

Office space available for lease in Mount Pleasant, SC.

Renovated Shopping Center on Hwy 17

Renovated Shopping Center on Hwy 17

627 Johnnie Dodds Blvd, Mount Pleasant, SC 29464

$32 SF/Yr

103,036 sqft

Highly visible, renovated shopping center with frontage on Hwy 17.

Professional Office Building with Parking

Professional Office Building with Parking

845 Lowcountry Boulevard # A, Mount Pleasant, SC 29464

Contact for pricing

4,238 sqft

Office suites with windows, shared conference space, and free on-site parking in a high-visibility corridor.

Freestanding Retail Building with Patio

Freestanding Retail Building with Patio

832 Coleman Blvd, Mount Pleasant, SC 29464

Contact for pricing

3,861 sqft

Freestanding brick retail building with ample on-site parking, patio, and an open floor plan plus rear office and storage.

Class A Medical Office Building

Class A Medical Office Building

1280 Hospital Drive Unit 100, Mount Pleasant, SC 29464

Contact for pricing

2,582 sqft

Class A medical office building with covered main entrance and abundant surface parking.

Furnished Executive Office Suite

Furnished Executive Office Suite

10 Shem Drive #100-E, Mount Pleasant, SC 29464

Contact for pricing

110 sqft

Corner office E features multiple windows and furnished executive finishes with all utilities included.

Restaurant and Entertainment Space

Restaurant and Entertainment Space

730 Coleman Boulevard # C, Mount Pleasant, SC 29464

Contact for pricing

11,122 sqft

Restaurant and entertainment suite includes duck-pin bowling lanes, axe throwing cages, and a built-in bar outdoor dining area.

Retail Space in CVS-Anchored Center

Retail Space in CVS-Anchored Center

1405 Ben Sawyer Boulevard, Mount Pleasant, SC 29464

Contact for pricing

1,960 sqft

Well-located storefront space in an open-air retail center with strong visibility and flexible layout options.

Strip Mall Retail Shops

Strip Mall Retail Shops

280 West Coleman Boulevard & 976 Houston Northcutt Boulevard, Mount Pleasant, SC 29464

Contact for pricing

4,602 sqft

Busy boutique shopping center offering 35 small retail shop spaces.

Industrial Flex Warehouse Facility

Industrial Flex Warehouse Facility

918 Wando Park Blvd, Mount Pleasant, SC 29464

Contact for pricing

13,098 sqft

Temperature-controlled flex warehouse includes 10,000 SF of office and multiple drive-in and dock-high loading doors.

Gold's Gym Retail Inline Space

Gold's Gym Retail Inline Space

730 Coleman Blvd, Mount Pleasant, SC 29464

Contact for pricing

1,400 sqft

Approximately 1,400 SF former kids club space offers open layout access from Gold’s Gym main foyer.

Mt Pleasant, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Mt Pleasant, SC with 101 listings featured on our commercial real estate exchange. The current inventory includes 207,991 square feet of properties with an estimated lease value of $408.89 /Mo.

Estimated lease rates for Commercial real estate in Mt Pleasant, SC begin at $6.16 SF/Yr, with an average of $34.07 SF/Yr and extend to $140.73 SF/Yr.

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