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    Depew, NY Commercial Real Estate for Lease

    110 results
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    Versatile Space in Catalyst Fitness Plaza
    $12 SF/Yr
    23,000 SF

    Versatile Space in Catalyst Fitness Plaza

    5087 Broadway, Depew, NY 14043

    Medical office, retail, and warehouse spaces available for lease.

    • High‑traffic corner location on Broadway & Penora Street with access from both streets.
    • Diverse tenant mix including national retailers like Tops, Big Lots, and Dollar Tree.
    • Ample parking with over 240 spaces.
    • Available 23,000 +/- SF warehouse space with 2 docks and 2 drive‑in doors, divisible from 7,000 +/- SF.
    • Existing 5,500 +/- SF medical office space with 23 +/- private rooms and 4 restrooms, convertible to retail.
    Updated: Mar 5
    View details
    Prime Location Retail Spaces Available
    $18 SF/Yr
    2,000 SF

    Prime Location Retail Spaces Available

    5102 Genesee Street, Depew, NY 14043

    Retail spaces for lease with high visibility and traffic.

    • Extremely high traffic location: Over 60,000 cars daily at the intersection of Transit Road and Genesee Street.
    • Two space options available: 1,200 +/- SF turn‑key ready and 2,000 +/- SF end‑cap space ready for build‑out.
    • Excellent accessibility: Located near I‑90, Kensington Expressway (Route 33), and Buffalo‑Niagara International Airport.
    • Ample parking and excellent visibility.
    • Located in Cheektowaga, the second‑largest suburb of Buffalo, with a population of over 88,000.
    Updated: Mar 5
    View details
    Free-Standing Building Near Airport
    $12 SF/Yr
    3,780 SF

    Free-Standing Building Near Airport

    One-story, 3,780 SF building with parking near Buffalo Airport.

    1505-1517 Cleveland Drive, Cheektowaga, NY 14225
    View details
    Class A Office Sublease
    $21 SF/Yr
    8,000 SF

    Class A Office Sublease

    Class A office space for sublease with showroom area.

    4455 Genesee St, Cheektowaga, NY 14225
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    Walden Avenue Professional Office Space
    $1,250 /Mo
    5,600 SF

    Walden Avenue Professional Office Space

    Well-appointed 2nd-floor office space, ideal for professional use.

    3260 Walden Avenue, Depew, NY 14043
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    Retail Center Near Walden Galleria
    $12 SF/Yr
    2,273 SF

    Retail Center Near Walden Galleria

    68,000 SF retail center near I-90 and Walden Galleria.

    2130 Walden Avenue, Cheektowaga, NY 14225
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    Retail Space on Broadway Available
    $2,500 /Mo
    1,720 SF

    Retail Space on Broadway Available

    Retail space for rent with high traffic and ample parking.

    4990 Broadway, Depew, NY 14043
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    Renovated Retail Space with High Visibility
    $16 SF/Yr

    Renovated Retail Space with High Visibility

    Subdividable retail space with high traffic and ample parking.

    2675 Union Road & William St, Cheektowaga, NY 14227
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    Modern Office Spaces in Cheektowaga
    $12 SF/Yr
    33,689 SF

    Modern Office Spaces in Cheektowaga

    Premier office spaces with modern facilities and convenient location.

    301, 303, 305 Cayuga Road, Cheektowaga, NY 14225
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    Commercial Land on Walden Avenue
    $1,850 /Mo
    2,342,134,080 SF

    Commercial Land on Walden Avenue

    Commercial land for lease on Walden Avenue near Dick Road.

    3003 Walden Ave, Depew, NY 14043
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    Lancaster Plaza Retail/Warehouse/Office Space
    Contact for pricing
    15,611 SF

    Lancaster Plaza Retail/Warehouse/Office Space

    Retail, warehouse, and office space available in Lancaster, NY.

    3291 Walden Ave, Lancaster, NY 14043
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    Former Convenience Store and Deli
    Contact for pricing
    1,500 SF

    Former Convenience Store and Deli

    1,500 SF space ready for lease on Genesee Street.

    3035 Genesee Street, Cheektowaga, NY 14225
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    Transit Road Retail/Office Space
    Contact for pricing
    1,500 SF

    Transit Road Retail/Office Space

    High-traffic retail/office space available on Transit Road.

    6348 Transit Road, Cheektowaga, NY 14225
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    Retail Space on Genesee Street
    Contact for pricing
    900 SF

    Retail Space on Genesee Street

    900+/- SF retail space with high visibility and accessibility.

    3035 Genesee Street, Cheektowaga, NY 14225
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    Former Salon Space Available
    Contact for pricing
    1,500 SF

    Former Salon Space Available

    Former salon space available for lease with customization options.

    3035 Genesee Street, Cheektowaga, NY 14225
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    Transit Road Commercial Opportunity
    Contact for pricing

    Transit Road Commercial Opportunity

    Commercial property on Transit Road with equipment included and parking.

    5460 Transit Road, Depew, NY 14043
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    Transit Road Retail/Office Space
    $13 SF/Yr
    1,500 SF

    Transit Road Retail/Office Space

    High-traffic location near supermarket and new apartments.

    6338-6348 Transit Rd, Depew, NY
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    Transit Road Retail Space Available
    Contact for pricing
    1,200 SF

    Transit Road Retail Space Available

    Newly renovated 1,200+/- SF retail space on Transit Road.

    6354 Transit Road, Depew, NY 14043
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    Two-Story Office Building Available
    $10 SF/Yr
    1,902 SF

    Two-Story Office Building Available

    Two-story, 1902 SF office building with parking.

    2375 Union Road, Cheektowaga, NY 14227
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    Retail Space on Busy Street
    Contact for pricing

    Retail Space on Busy Street

    High visibility retail space with parking and signage available.

    3637 Walden Ave, Lancaster, NY 14086
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    Lancaster Warehouse with Office Space
    $12 SF/Yr

    Lancaster Warehouse with Office Space

    5,000 SF warehouse with 1,000 SF office space for lease.

    933 Ransom Road, Lancaster, NY 14086
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    New Lancaster Warehouse/Storage Bays
    $1.00 SF/Yr

    New Lancaster Warehouse/Storage Bays

    New warehouse/storage bays in Lancaster, NY with ample parking.

    4425 Walden Ave, Lancaster, NY 14086
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    Lancaster Warehouse/Retail/Office Space Available
    Contact for pricing

    Lancaster Warehouse/Retail/Office Space Available

    Versatile space near Transit Rd with high traffic volume.

    3283-3291 Walden Ave, Lancaster, NY 14043
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    Union Road Retail/Office Space Available
    Contact for pricing

    Union Road Retail/Office Space Available

    Retail and office spaces available for lease on Union Road.

    3800 - 3806 Union Road, Cheektowaga, NY 14225
    View details

    Depew, NY Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Depew, NY with 110 listings featured on our commercial real estate exchange. The current inventory includes 887,099,400 square feet of properties with an estimated lease value of $37 SF/Yr.

    Estimated lease rates for Commercial real estate in Depew, NY begin at $12 SF/Yr, with an average of $12 SF/Yr and extend to $13 SF/Yr.
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    Most Searched ZIP Codes in Depew, NY

    • 14043
    • 14225
    • 14086
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    • 14215
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