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    Portsmouth, NH Commercial Real Estate for Lease

    92 results
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    Portsmouth
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    Portsmouth

    All-inclusive access to workspace, virtual office and meeting rooms in 505 Montgomery

    170 Commerce Way, Portsmouth, NH 03801
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    Retail/Office Space in Portsmouth
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    Retail/Office Space in Portsmouth

    33 Deer St, Portsmouth, NH 03801

    Updated retail/office space with patio in Portsmouth's North End.

    • Prime location on desirable Deer Street in Portsmouth's revitalized North End.
    • Newly updated interior with fresh paint and new flooring.
    • Generous patio/outdoor space adjacent to the Sheraton Hotel and Conference Center.
    • One underground parking space included with rent.
    • Rent includes water, sewer, and trash.
    Updated: Mar 3
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    Prime Portsmouth Commercial Space Available
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    4,792 SF

    Prime Portsmouth Commercial Space Available

    1290 Woodbury Ave, Portsmouth, NH 03801

    1,470 SF office/retail space in high-traffic Portsmouth location.

    • High‑visibility location on Woodbury Avenue in a high‑traffic commercial area.
    • Easy access to Interstate 95 and proximity to shopping plazas (Market Basket, Whole Foods).
    • Flexible 1,470 SF interior layout easily reconfigured for various professional, medical, or retail uses.
    • Ample on‑site parking for clients and employees.
    • Abundant natural light and 10' ceilings creating a bright, welcoming atmosphere.
    Updated: Feb 24
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    Downtown Portsmouth Office For Lease
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    Downtown Portsmouth Office For Lease

    Office space for lease in downtown Portsmouth, available immediately.

    159 Middle St, Portsmouth, NH 03801
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    Portsmouth Office Space For Lease
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    48,787 SF

    Portsmouth Office Space For Lease

    Versatile office space in Portsmouth, accessible from city or bypass.

    500 Maplewood Ave, Portsmouth, NH 03801
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    Prime Retail Space on Route 1
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    61,855 SF

    Prime Retail Space on Route 1

    7,000 SF retail space in high-visibility Portsmouth location.

    2299 Lafayette Rd, Portsmouth, NH 03801
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    Downtown Portsmouth Modern Office Space
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    Downtown Portsmouth Modern Office Space

    Modern office space in downtown Portsmouth with parking and amenities.

    299 Hanover St, Portsmouth, NH 03801
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    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    Versatile office space available for lease in Portsmouth, New Hampshire.

    500 Maplewood Ave, Portsmouth, NH 03801
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    Portsmouth Commercial Space For Lease
    $11 SF/Yr
    3,921 SF

    Portsmouth Commercial Space For Lease

    Commercial space with overhead doors, near Interstate 95.

    500 Maplewood Ave, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant downtown location.

    10 Vaughan St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant, walkable downtown location.

    10 Vaughan St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suites Available
    Contact for pricing

    Downtown Portsmouth Office Suites Available

    Move-in-ready office suites in a vibrant downtown location.

    10 Vaughan St, Portsmouth, NH 03801
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    Prime Portsmouth Commercial Space Available
    Contact for pricing
    174,240 SF

    Prime Portsmouth Commercial Space Available

    High-traffic location suitable for retail, medical, restaurant, or office use.

    750 Lafayette Rd, Portsmouth, NH 03801
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    Versatile Commercial Space on Lafayette Road
    Contact for pricing
    174,240 SF

    Versatile Commercial Space on Lafayette Road

    Adaptable space suitable for medical, retail, restaurant, or office use.

    750 Lafayette Rd, Portsmouth, NH 03801
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    Professional Office Space For Lease
    Contact for pricing
    1,500 SF

    Professional Office Space For Lease

    Individual offices for healthcare practitioners and therapists in Portsmouth, NH.

    4 Greenleaf Woods Dr, Portsmouth, NH 03801
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    Studio/Flex Space For Lease
    $1,500 / Mo

    Studio/Flex Space For Lease

    Studio/flex space available near Pease International Tradeport.

    282 Corporate Dr, Portsmouth, NH 03801
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    Renovated Office Space Available
    $1,800 / Mo

    Renovated Office Space Available

    Office space for lease in Lafayette West Industrial Park.

    210 West Rd, Portsmouth, NH 03801
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    Portsmouth Office Building For Lease
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    Portsmouth Office Building For Lease

    Office building for lease with high visibility and signage.

    3201 Lafayette Rd, Portsmouth, NH 03801
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    Historic Portsmouth Office Space Available
    $29 SF/Yr

    Historic Portsmouth Office Space Available

    1,600 SF ground-floor office space in historic Old City Hall.

    126 Daniel St, Portsmouth, NH 03801
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    Retail/Office Space For Lease
    $17 SF/Yr

    Retail/Office Space For Lease

    2,050± SF retail/office space with ample parking.

    72 Mirona Rd, Portsmouth, NH 03801
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    Portsmouth Commercial Space For Rent
    $15 SF/Yr

    Portsmouth Commercial Space For Rent

    2,333± SF commercial space in a convenient Portsmouth location.

    875 Greenland Rd, Portsmouth, NH 03801
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    Refurbished Office Suites For Lease
    $7 SF/Yr

    Refurbished Office Suites For Lease

    Newly refurbished office suites available near Pease International Tradeport.

    282 Corporate Dr, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space
    $2,000 / Mo

    Downtown Portsmouth Office Space

    Professional office space in the heart of Downtown Portsmouth.

    507 State St, Portsmouth, NH 03801
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    Portsmouth Office/Retail Space For Rent
    $3,850 / Mo

    Portsmouth Office/Retail Space For Rent

    1,470 SF office/retail space on Woodbury Avenue, Portsmouth, NH.

    1290 Woodbury Ave, Portsmouth, NH 03801
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    Portsmouth, NH Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Portsmouth, NH with 138 listings featured on our commercial real estate exchange. The current inventory includes 27,681,116,760 square feet of properties with an estimated lease value of $425 /Mo.

    Estimated lease rates for Commercial real estate in Portsmouth, NH begin at $1.00 SF/Yr, with an average of $17 SF/Yr and extend to $38 SF/Yr.
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