Sign Up Successful!
You now have access to more from Realmo!
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search
    List
    Map

    Portsmouth, NH Commercial Real Estate for Lease

    87 results
    Notify Me
    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    500 Maplewood Ave, Portsmouth, NH 03801

    Versatile office space in Portsmouth, accessible from city or bypass.

    • Highly accessible location just off Route 1 Bypass in Portsmouth.
    • Versatile first‑floor layout with open showroom/bullpen, 8 private offices, and 2 conference/team rooms.
    • Includes a kitchen and 2 restrooms.
    • Additional storage rooms on the first floor.
    • Large (3,921 sf) unfinished second‑floor space suitable for storage or future office build‑out.
    Last Update: Sep 27
    View details
    Portsmouth Commercial Lease Opportunity
    $10 SF/Yr
    3,921 SF

    Portsmouth Commercial Lease Opportunity

    500 Maplewood Ave, Portsmouth, NH 03801

    Commercial lease opportunity near Interstate 95 in Portsmouth, NH.

    • Prime location on Route 1 Bypass, near Portsmouth Traffic Circle and I‑95.
    • Equipped for high‑volume tire shop operation including tire balancer, compressor, tire machine, and truck tire racks.
    • Features four overhead doors.
    • Formerly Hanscom's Truck Stop.
    • Year Built: 1942.
    Last Update: Sep 27
    View details
    Prime Portsmouth Commercial Space Available
    Contact for pricing
    4,792 SF

    Prime Portsmouth Commercial Space Available

    1,470 SF office/retail space in high-traffic Portsmouth location.
    1290 Woodbury Ave, Portsmouth, NH 03801
    View details
    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant downtown location.
    10 Vaughan St, Portsmouth, NH 03801
    View details
    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant, walkable downtown location.
    10 Vaughan St, Portsmouth, NH 03801
    View details
    Downtown Portsmouth Office Suites Available
    Contact for pricing

    Downtown Portsmouth Office Suites Available

    Move-in-ready office suites in a vibrant downtown location.
    10 Vaughan St, Portsmouth, NH 03801
    View details
    Prime Portsmouth Commercial Space Available
    Contact for pricing
    174,240 SF

    Prime Portsmouth Commercial Space Available

    High-traffic location suitable for retail, medical, restaurant, or office use.
    750 Lafayette Rd, Portsmouth, NH 03801
    View details
    Portsmouth Office Building For Lease
    Contact for pricing

    Portsmouth Office Building For Lease

    Stand-alone Portsmouth office building with great visibility and signage.
    3201 Lafayette Rd, Portsmouth, NH 03801
    View details
    Portsmouth Professional Office Space Available
    Contact for pricing
    1,500 SF

    Portsmouth Professional Office Space Available

    Individual offices for health practitioners, flexible lease terms, utilities included.
    4 Greenleaf Woods Dr, Portsmouth, NH 03801
    View details
    Versatile Commercial Space on Lafayette Road
    Contact for pricing
    174,240 SF

    Versatile Commercial Space on Lafayette Road

    Adaptable Portsmouth space suitable for medical, retail, restaurant, or office.
    750 Lafayette Rd, Portsmouth, NH 03801
    View details
    Turnkey Tire Shop For Lease
    Contact for pricing
    52,272 SF

    Turnkey Tire Shop For Lease

    Fully outfitted tire shop near Interstate 95 in Portsmouth.
    500 Maplewood Ave, Portsmouth, NH 03801
    View details
    Portsmouth Office Space For Lease
    Contact for pricing
    48,787 SF

    Portsmouth Office Space For Lease

    Versatile office space in Portsmouth, accessible from city or bypass.
    500 Mapplewood Ave, Portsmouth, NH 03801
    View details
    Downtown Portsmouth Office For Lease
    Contact for pricing

    Downtown Portsmouth Office For Lease

    Single office in downtown Portsmouth with utilities included. Available 2025.
    33 Deer St, Portsmouth, NH 03801
    View details
    Portsmouth Retail Space For Lease
    Contact for pricing
    78,430 SF

    Portsmouth Retail Space For Lease

    Large Retail Space, Multiple Units Available
    100 Durgin Ln, Portsmouth, NH 03801
    View details
    Portsmouth Medical Office Space
    $19 SF/Yr
    55,200 SF

    Portsmouth Medical Office Space

    Prime Medical Suites, I-95 Access
    330 Borthwick Ave, Portsmouth, NH 03801
    View details
    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    8,202 SF Office, Prime Location
    500 Maplewood Ave, Portsmouth, NH 03801
    View details
    Vaughan Mall Office Suites
    $18 SF/Yr
    38,745 SF

    Vaughan Mall Office Suites

    Portsmouth, NH Office Space Available
    10 Vaughan Mall, Portsmouth, NH 03801
    View details
    Portsmouth Tire Shop - Turnkey!
    $10 SF/Yr
    3,921 SF

    Portsmouth Tire Shop - Turnkey!

    High-Volume Tire Business, Fully Equipped
    500 Maplewood Ave, Portsmouth, NH 03801
    View details
    Historic Portsmouth Office Building
    $30 SF/Yr
    4,928 SF

    Historic Portsmouth Office Building

    Spacious Office Space Available, Prime Location
    110 Chapel St, Portsmouth, NH 03801
    View details
    Portsmouth Office/Storage Space Available
    $14 SF/Yr
    62,322 SF

    Portsmouth Office/Storage Space Available

    900 SF heated space, prime Portsmouth location.
    300 Constitution Ave, Portsmouth, NH 03801
    View details
    Prime Pease Tradeport Office Space
    $17 SF/Yr
    14,800 SF

    Prime Pease Tradeport Office Space

    Modern Executive Suites, 14,800 SF Available
    183 International Dr, Portsmouth, NH 03801
    View details
    Portsmouth Office Suites for Lease
    $23 SF/Yr
    58,347 SF

    Portsmouth Office Suites for Lease

    Affordable NH Office Space, 120-204 SF
    170 West Rd, Portsmouth, NH 03801
    View details
    Portsmouth Executive Office Space
    $28 SF/Yr
    47,745 SF

    Portsmouth Executive Office Space

    Prime Portsmouth Office, Flexible Suites Available
    100 Borthwick Ave, Portsmouth, NH 03801
    View details
    Class A Office Space for Lease
    $12 SF/Yr
    62,322 SF

    Class A Office Space for Lease

    Modern, 11,412 SF Executive Office Suite
    300 Constitution Ave, Portsmouth, NH 03801
    View details

    Portsmouth, NH Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Portsmouth, NH with 124 listings featured on our commercial real estate exchange. The current inventory includes 35,969,016,600 square feet of properties with an estimated lease value of $1,000 /Mo.

    Estimated lease rates for Commercial Real Estate in Portsmouth, NH begin at $1.00 SF/Yr, with an average of $20 SF/Yr and extend to $85 SF/Yr.

    In Portsmouth, NH, current lease rates show:

    • Office Properties & Spaces positioned at $22
    • Office space measuring $21
    • Other office properties assessed at $22
    • Retail properties calculated at $13
    List
    Map

    Browse Commercial real estate for Lease Near Portsmouth, NH

    Popular Searches in Portsmouth, NH

    Popular Categories

    Most Searched ZIP Codes in Portsmouth, NH

    • 03801

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Create New Password
    • At least 8 characters
    • Contains both letters and numbers
    • Contains uppercase and lowercase letters
    • At most 32 characters
    • Password required
    • Password reset link has expired. Please request a new one.