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Middlesex County, MA Commercial Real Estate for Lease

1,219 results
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Wilmington Office Space For Lease
$2,000 / Mo
1,108 SF

Wilmington Office Space For Lease

25 Lowell St, Wilmington, MA 01887

1,108 SF office space in Wilmington, MA for lease.

  • Prime location on Route 129, less than 1.5 miles from I‑93.
  • Functional layout with three exam rooms and two private offices.
  • Private ADA entrance from the parking lot in addition to main lobby access.
  • Ample parking available.
  • Signage opportunities on the building.
Updated: Apr 7, 2025
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Westford Retail Space For Lease
$2,900 / Mo
1,000 SF

Westford Retail Space For Lease

175 Littleton Rd, Westford, MA 01886

1000 sq ft retail space in high-traffic Westford location.

  • Prime location on the busiest street in Westford.
  • High traffic strip mall location.
  • Flexible 1000 sq ft of space.
  • End unit.
  • Built in 2021.
Updated: Dec 6, 2025
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Westford Retail Space For Lease
$3,900 / Mo
1,479 SF

Westford Retail Space For Lease

1479 SF retail space in high-traffic Westford strip mall.

175 Littleton Rd, Westford, MA 01886
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Westford Retail Space For Lease
$3,800 / Mo
1,428 SF

Westford Retail Space For Lease

1428 SF retail space in high-traffic Westford strip mall.

175 Littleton Rd, Westford, MA 01886
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Office Space on Littleton Common
$700 / Mo
7,749 SF

Office Space on Littleton Common

Highly visible office space for rent near 495.

17 Stevens St, Littleton, MA 01460
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Framingham Office Space Available
$1,600 / Mo
6,098 SF

Framingham Office Space Available

First floor office space for rent in Framingham, MA.

12 Library St, Framingham, MA 01701
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Commercial Building on Busy Corner
$2,800 / Mo
6,068 SF

Commercial Building on Busy Corner

Freestanding building suitable for office or retail use.

14 Dinley St, Dracut, MA 01826
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West Newton First-Floor Office Space
$2,375 / Mo
4,792 SF

West Newton First-Floor Office Space

Professional office space in West Newton with flexible lease terms.

76 Chestnut St, Newton, MA 02465
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Renovated Office Space in Stoneham
$1,350 / Mo
4,434 SF

Renovated Office Space in Stoneham

Top-floor office space in a vibrant, high-traffic location.

272 Main St, Stoneham, MA 02180
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Hopkinton Office/Medical Space For Rent
$19 SF/Yr
355,885 SF

Hopkinton Office/Medical Space For Rent

1,932 SF office/medical space available for lease.

22 South St, Hopkinton, MA 01748
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Former Parish Center For Lease
$8 SF/Yr
62,291 SF

Former Parish Center For Lease

Spacious 17,000 SF former parish center on 1.43 acres.

401 Fellsway W, Medford, MA 02155
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Littleton Office Space For Rent
$2,000 / Mo
27,007 SF

Littleton Office Space For Rent

Bright, six-room office space with great visibility and easy access.

4 Robinson Rd, Littleton, MA 01460
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East Arlington Office Space
$950 / Mo
3,777 SF

East Arlington Office Space

330 SF office space in prime East Arlington location.

99 Massachusetts Ave, Arlington, MA 02474
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Former Convent and Dormitory Lease
$15 SF/Yr
100,188 SF

Former Convent and Dormitory Lease

Versatile Medford commercial space, convenient location, ample parking.

2520 Mystic Valley Pkwy, Medford, MA 02155
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Downtown Lowell Retail Space Available
$2,000 / Mo
5,227 SF

Downtown Lowell Retail Space Available

600 SF retail space in a high-traffic downtown location.

183 Appleton St, Lowell, MA 01852
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Prime Main Street Commercial Unit
$600 / Mo
9,435 SF

Prime Main Street Commercial Unit

Charming retail space in the heart of Pepperell, MA.

152 Main St, Pepperell, MA 01463
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Littleton Office Space For Rent
$1,300 / Mo
900 SF

Littleton Office Space For Rent

Charming office space in central Littleton, available immediately.

442 King St Unit, Littleton, MA 01460
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Professional Office Space in Lowell
$750 / Mo

Professional Office Space in Lowell

Well-maintained office suite ideal for wellness, counseling, or consulting practices.

491 Thorndike St, Lowell, MA 01854
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Charming Retail/Office Space in Sudbury
$2,775 / Mo
700 SF

Charming Retail/Office Space in Sudbury

Renovated retail or office space in historic Sudbury building.

353 Boston Post Rd, Sudbury, MA 01776
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Private Office Space Near Transit
$1,400 / Mo
200 SF

Private Office Space Near Transit

Private office space in classic brownstone near Washington Square train.

1577 Beacon St, Brookline, MA 02445
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Top Floor Brookline Office Space
$1,000 / Mo
200 SF

Top Floor Brookline Office Space

Private office space with treelined views near Washington Square.

1577 Beacon St, Brookline, MA 02445
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Charming Retail/Office Space Available
$4,999 / Mo
1,400 SF

Charming Retail/Office Space Available

Renovated retail or office space in historic Sudbury building.

353 Boston Post Rd #Suite, Sudbury, MA 01776
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Loft Office Space in Medford
$1,750 / Mo

Loft Office Space in Medford

Loft office space in the heart of Medford Square.

92 High St, Medford, MA 02155
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Framingham Office Space on Route 9
$30 SF/Yr
1,920 SF

Framingham Office Space on Route 9

Professional office space with high visibility and convenient highway access.

50 Worcester Rd, Framingham, MA 01702
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Middlesex County, MA Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Middlesex County, MA with 1806 listings featured on our commercial real estate exchange. The current inventory includes 175,180,712,008 square feet of properties with an estimated lease value of $40,818.

Estimated lease rates for Commercial Real Estate in Middlesex County, MA begin at $0.76 SF/Yr, with an average of $127 SF/Yr and extend to $31,920.

In Middlesex County, MA, current lease rates show:

  • Office Properties & Spaces positioned at $164
  • Office space measuring $182
  • Retail properties assessed at $418
  • Individual retail properties calculated at $32
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