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    Middlesex County, MA Commercial Real Estate for Lease

    1,222 results
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    Spacious Marlborough Apartment in Victorian Home
    $3,000 / Mo
    1,949 SF

    Spacious Marlborough Apartment in Victorian Home

    118 Elm St, Marlborough, MA 01752

    Spacious 3-bedroom, 1.5-bath apartment in a classic Victorian two-family home.

    • Spacious 1,678 sq ft two‑level layout with 3 well‑sized bedrooms.
    • Prime location: Minutes to downtown Marlborough, close to amenities, and convenient access to major routes (Route 20, Route 85, I‑290 & I‑495).
    • Hardwood floors throughout and freshly painted interior.
    • Spacious eat‑in kitchen.
    • Private entrance.
    Updated: Jan 16
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    Office Space in Littleton Center
    $1,300 / Mo
    900 SF

    Office Space in Littleton Center

    442 King St Unit, Littleton, MA 01460

    Charming office space with great visibility in the center of town.

    • Great visibility in center of town
    • Flexible common space with bathroom and small kitchen area
    • Two private rooms ideal for offices, complete with sitting/waiting room
    • Close to major routes and shopping
    • Trash and snow removal provided
    Updated: Jan 8
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    Renovated Office Space in Stoneham
    $1,350 / Mo
    4,434 SF

    Renovated Office Space in Stoneham

    Top-floor office space in Stoneham with high visibility and accessibility.

    272 Main St, Stoneham, MA 02180
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    Wilmington Office Space For Lease
    $2,000 / Mo
    1,108 SF

    Wilmington Office Space For Lease

    1,108 SF office space in Wilmington, MA for lease.

    25 Lowell St, Wilmington, MA 01887
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    Westford Retail Space For Lease
    $2,900 / Mo
    1,000 SF

    Westford Retail Space For Lease

    1000 sq ft retail space in high-traffic Westford location.

    175 Littleton Rd, Westford, MA 01886
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    Westford Retail Space For Lease
    $3,900 / Mo
    1,479 SF

    Westford Retail Space For Lease

    1479 SF retail space in high-traffic Westford strip mall.

    175 Littleton Rd, Westford, MA 01886
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    Westford Retail Space For Lease
    $3,800 / Mo
    1,428 SF

    Westford Retail Space For Lease

    1428 SF retail space in high-traffic Westford strip mall.

    175 Littleton Rd, Westford, MA 01886
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    Office Space on Littleton Common
    $700 / Mo
    7,749 SF

    Office Space on Littleton Common

    Highly visible office space for rent near 495.

    17 Stevens St, Littleton, MA 01460
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    Framingham Office Space Available
    $1,600 / Mo
    6,098 SF

    Framingham Office Space Available

    First floor office space for rent in Framingham, MA.

    12 Library St, Framingham, MA 01701
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    Commercial Building on Busy Corner
    $2,800 / Mo
    6,068 SF

    Commercial Building on Busy Corner

    Freestanding building suitable for office or retail use.

    14 Dinley St, Dracut, MA 01826
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    West Newton First-Floor Office Space
    $2,375 / Mo
    4,792 SF

    West Newton First-Floor Office Space

    Professional office space in West Newton with flexible lease terms.

    76 Chestnut St, Newton, MA 02465
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    Renovated Office Space in Stoneham
    $1,350 / Mo
    4,434 SF

    Renovated Office Space in Stoneham

    Top-floor office space in a vibrant, high-traffic location.

    272 Main St, Stoneham, MA 02180
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    Hopkinton Office/Medical Space For Rent
    $19 SF/Yr
    355,885 SF

    Hopkinton Office/Medical Space For Rent

    1,932 SF office/medical space available for lease.

    22 South St, Hopkinton, MA 01748
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    Former Parish Center For Lease
    $8 SF/Yr
    62,291 SF

    Former Parish Center For Lease

    Spacious 17,000 SF former parish center on 1.43 acres.

    401 Fellsway W, Medford, MA 02155
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    Littleton Office Space For Rent
    $2,000 / Mo
    27,007 SF

    Littleton Office Space For Rent

    Bright, six-room office space with great visibility and easy access.

    4 Robinson Rd, Littleton, MA 01460
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    East Arlington Office Space
    $950 / Mo
    3,777 SF

    East Arlington Office Space

    330 SF office space in prime East Arlington location.

    99 Massachusetts Ave, Arlington, MA 02474
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    Former Convent and Dormitory Lease
    $15 SF/Yr
    100,188 SF

    Former Convent and Dormitory Lease

    Versatile Medford commercial space, convenient location, ample parking.

    2520 Mystic Valley Pkwy, Medford, MA 02155
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    Downtown Lowell Retail Space Available
    $2,000 / Mo
    5,227 SF

    Downtown Lowell Retail Space Available

    600 SF retail space in a high-traffic downtown location.

    183 Appleton St, Lowell, MA 01852
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    Prime Main Street Commercial Unit
    $600 / Mo
    9,435 SF

    Prime Main Street Commercial Unit

    Charming retail space in the heart of Pepperell, MA.

    152 Main St, Pepperell, MA 01463
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    Littleton Office Space For Rent
    $1,300 / Mo
    900 SF

    Littleton Office Space For Rent

    Charming office space in central Littleton, available immediately.

    442 King St Unit, Littleton, MA 01460
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    Professional Office Space in Lowell
    $750 / Mo

    Professional Office Space in Lowell

    Well-maintained office suite ideal for wellness, counseling, or consulting practices.

    491 Thorndike St, Lowell, MA 01854
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    Charming Retail/Office Space in Sudbury
    $2,775 / Mo
    700 SF

    Charming Retail/Office Space in Sudbury

    Renovated retail or office space in historic Sudbury building.

    353 Boston Post Rd, Sudbury, MA 01776
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    Private Office Space Near Transit
    $1,400 / Mo
    200 SF

    Private Office Space Near Transit

    Private office space in classic brownstone near Washington Square train.

    1577 Beacon St, Brookline, MA 02445
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    Top Floor Brookline Office Space
    $1,000 / Mo
    200 SF

    Top Floor Brookline Office Space

    Private office space with treelined views near Washington Square.

    1577 Beacon St, Brookline, MA 02445
    View details

    Middlesex County, MA Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Middlesex County, MA with 1808 listings featured on our commercial real estate exchange. The current inventory includes 174,605,171,509 square feet of properties with an estimated lease value of $40,587.

    Estimated lease rates for Commercial Real Estate in Middlesex County, MA begin at $0.76 SF/Yr, with an average of $129 SF/Yr and extend to $31,920.

    In Middlesex County, MA, current lease rates show:

    • Office Properties & Spaces positioned at $167
    • Office space measuring $186
    • Retail properties assessed at $432
    • Industrial properties calculated at $18
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