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    Sikeston, MO Commercial Land for Sale

    11 results
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    Map
    Commercial Land in Sikeston, MO
    $400,000
    2.63 Acres

    Commercial Land in Sikeston, MO

    109 Stallcup Dr, Sikeston, MO 63801

    2.63 acres in booming retail and hospitality area.

    • Premium commercial location in Sikeston's retail and hospitality area.
    • Over 2.5 acres of commercial property.
    • Close proximity to Wal‑Mart Supercenter, new hotels, shopping, and restaurants.
    • Half mile to the intersection of US Highways 60 & 61.
    • Level exterior features.
    Updated: Mar 13
    View details
    Commercial Land on Highway 61
    $144,000
    1.01 Acres

    Commercial Land on Highway 61

    103 Grove St, Sikeston, MO 63801

    Commercial land on high-traffic route near Sikeston Industrial Park.

    • High‑traffic location on Highway 61, ideal for business visibility.
    • Zoned C‑1 Neighborhood Shopping District, suitable for retail and personal services.
    • Proximity to Sikeston Industrial Park and Southeast Missouri State University campus.
    • Adjacent to Greenbriar and Fairfield Subdivisions, providing a built‑in customer base.
    • Perfect for office, medical, and professional services.
    Updated: Oct 7, 2025
    View details
    Commercial Land in Retail Area
    $500,000
    1.05 Acres

    Commercial Land in Retail Area

    1.05 acres of commercial land for development in Sikeston.

    1209 Lawrence St, Sikeston, MO 63801
    View details
    Commercial Land in Sikeston, MO
    $500,000
    1.24 Acres

    Commercial Land in Sikeston, MO

    1.24 acre commercial lot near apartments and retail.

    1201 Lawrence St, Sikeston, MO 63801
    View details
    Commercial Land Ready For Development
    $199,000
    2.00 Acres

    Commercial Land Ready For Development

    Two-acre commercial lot available for development in Sikeston, Missouri.

    224 S Interstate Dr, Sikeston, MO 63801
    View details
    Prime Land for Commercial Development
    $3,960,000
    88.00 Acres

    Prime Land for Commercial Development

    88 acres at I-55 and I-57, Sikeston, MO.

    Ables Rd, Sikeston, MO 63801
    View details
    Commercial Land in Sikeston, MO
    $195,000
    0.72 Acres

    Commercial Land in Sikeston, MO

    Vacant, level commercial lot available in Sikeston, Missouri.

    116 Hospitality Dr, Sikeston, MO 63801
    View details
    Prime Land for Commercial Development
    $3,960,000

    Prime Land for Commercial Development

    Commercial land available at I-55 and I-57 interchange.

    Ables Rd, Sikeston, MO 63801
    View details
    Commercial Land on South Main
    Contact for pricing

    Commercial Land on South Main

    Highly visible land parcel suitable for retail development.

    1240 S Main St, Sikeston, MO 63801
    View details
    Commercial Land in Retail Area
    $500,000

    Commercial Land in Retail Area

    1.05 acre commercial land for development in Sikeston, Missouri.

    1209 Lawrence St, Sikeston, MO 63801
    View details
    Commercial Land on Stallcup Drive
    $500,000

    Commercial Land on Stallcup Drive

    1.24 acre commercial land for sale near retail.

    1201 Lawrence St, Sikeston, MO 63801
    View details
    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 11 Active listings in Sikeston, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    I-55 Frontage Development Opportunity
    Contact for pricing

    I-55 Frontage Development Opportunity

    5 acre commercial land parcel with I-55 frontage.

    337 State Highway P, New Madrid, MO 63869
    View details
    I-55 Land Parcel Opportunity
    $395,000

    I-55 Land Parcel Opportunity

    5 acre parcel suitable for truck stop or fuel station.

    337 State Highway P, New Madrid, MO 63869
    View details
    Commercial Land in Dexter, MO
    $2,000,000
    2.96 Acres

    Commercial Land in Dexter, MO

    Commercial property suitable for business, subdivision possible.

    W Bus Hwy 60, Dexter, MO 63841
    View details
    Commercial Land For Sale
    $495,000
    11.16 Acres

    Commercial Land For Sale

    11 acre commercial land available behind Wal-Mart.

    Two Mile Rd, Dexter, MO 63841
    View details

    Explore Off-Market Properties in Sikeston, MO

    Consider similar Off-Market properties in Sikeston, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1168 Stallcup Dr

    1168 Stallcup Dr

    VACANT COMMERCIAL LAND • 2.93 Acres
    Value Estimation by Request
    1168 Stallcup Dr, Sikeston, MO 63801
    View details
    1213 Cinema Dr

    1213 Cinema Dr

    VACANT COMMERCIAL LAND • 0.52 Acres
    Value Estimation by Request
    1213 Cinema Dr, Sikeston, MO 63801
    View details
    807 County Line Rd

    807 County Line Rd

    VACANT COMMERCIAL LAND • 5.00 Acres
    Value Estimation by Request
    807 County Line Rd, Sikeston, MO 63801
    View details
    807 County Line Rd

    807 County Line Rd

    VACANT COMMERCIAL LAND • 13.70 Acres
    Value Estimation by Request
    807 County Line Rd, Sikeston, MO 63801
    View details
    538 County Line Rd

    538 County Line Rd

    VACANT COMMERCIAL LAND • 27.30 Acres
    Value Estimation by Request
    538 County Line Rd, Sikeston, MO 63801
    View details
    1209 Lawrence St

    1209 Lawrence St

    VACANT COMMERCIAL LAND • 1.05 Acres
    Value Estimation by Request
    1209 Lawrence St, Sikeston, MO 63801-4321
    View details
    Lawrence St

    Lawrence St

    VACANT COMMERCIAL LAND • 0.74 Acres
    Value Estimation by Request
    Lawrence St, Sikeston, MO 63801
    View details
    Sikeston, MO 63801

    Sikeston, MO 63801

    VACANT COMMERCIAL LAND
    Value Estimation by Request
    Sikeston, MO 63801
    View details
    1209 Cinema Dr

    1209 Cinema Dr

    VACANT COMMERCIAL LAND • 1.72 Acres
    Value Estimation by Request
    1209 Cinema Dr, Sikeston, MO 63801
    View details
    Sikeston, MO 63801

    Sikeston, MO 63801

    VACANT COMMERCIAL LAND • 218.34 Acres
    Value Estimation by Request
    Sikeston, MO 63801
    View details
    831 County Line Rd

    831 County Line Rd

    VACANT COMMERCIAL LAND • 0.50 Acres
    Value Estimation by Request
    831 County Line Rd, Sikeston, MO 63801
    View details
    1201 Lawrence St

    1201 Lawrence St

    VACANT COMMERCIAL LAND • 1.24 Acres
    Value Estimation by Request
    1201 Lawrence St, Sikeston, MO 63801-4321
    View details
    1221 Hennings Dr

    1221 Hennings Dr

    VACANT COMMERCIAL LAND • 2.04 Acres
    Value Estimation by Request
    1221 Hennings Dr, Sikeston, MO 63801-6200
    View details

    Sikeston, MO Commercial Land Investment Opportunities Market Analysis

    Explore 59 commercial land for sale in Sikeston, MO, showcased through 11 active listings on our real estate platform. These investment opportunities span a total of 4,210,074 square feet of properties for sale, with an estimated market value of $5,898,000.

    Sale prices for commercial lots in Sikeston, MO start at $144,000, averaging $842,571, and reaching up to $3,960,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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