For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Retail
1
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Pickens County, SC Retail Properties for Lease

17 results
List
Map
Downtown Clemson Retail Space Available
$2,800 / Mo

Downtown Clemson Retail Space Available

382 College Ave Unit, Clemson, SC 29631

Retail space in downtown Clemson, formerly a coffee shop.

  • Prime downtown Clemson location.
  • Approximately 2100 sqf. of finished space.
  • Accessible from Kieth St.
  • Central heating and cooling.
  • Durable brick construction.
Updated: Dec 30, 2025
View details
Easley Retail Leasing Opportunity
$10 SF/Yr
16,528 SF

Easley Retail Leasing Opportunity

1943 East Main St, Easley, SC 29640

Turnkey retail space with high visibility and ample parking.

  • Turnkey retail space ready for immediate occupancy.
  • High‑visibility location at the gateway to Downtown Easley with ± 15,300 VPD.
  • Abundant on‑site parking available.
  • Open, spacious floor plan with high ceilings and ample lighting.
  • Multiple signage opportunities available.
View details
Retail Space Near Clemson University
Contact for pricing
1,233 SF

Retail Space Near Clemson University

Publix-anchored retail space with high visibility near Clemson University.

1390 Tiger Blvd, Clemson, SC 29631
View details
Remodeled Retail Building on Acreage
Contact for pricing
1,000 SF

Remodeled Retail Building on Acreage

Remodeled 1,000 SF retail building on 0.45 acres.

5536 Calhoun Memorial Hwy, Easley, SC 29640
View details
Freestanding Restaurant Space Available
Contact for pricing
4,029 SF

Freestanding Restaurant Space Available

4,029 SF freestanding restaurant with drive-thru in Clemson, SC.

1071 Tiger Blvd, Clemson, SC 29631
View details
Retail Space on Highway 123
Contact for pricing
1,200 SF

Retail Space on Highway 123

Retail space in Easley's trade area with high visibility.

6811 Calhoun Memorial Hwy, Easley, SC 29640
View details
Retail/Restaurant Space Near Clemson University
Contact for pricing
3,500 SF

Retail/Restaurant Space Near Clemson University

Retail/restaurant space with dedicated parking and lake access.

894 Tiger Blvd, Clemson, SC 29631
View details
Retail Space in High-Traffic Area
Contact for pricing
1,396 SF

Retail Space in High-Traffic Area

Retail space with strong tenant mix and high visibility.

6101 Calhoun Memorial Hwy, Easley, SC 29640
View details
Mixed-Use Property Near Clemson Campus
Contact for pricing

Mixed-Use Property Near Clemson Campus

Mixed-use property with residential and retail components near Clemson University.

111 Earle St, Clemson, SC 29631
View details
Retail/Restaurant Space Near Clemson University
Contact for pricing
1,401 SF

Retail/Restaurant Space Near Clemson University

Retail/restaurant spaces available in mixed-use student housing project.

114 Earle St, Clemson, SC 29631
View details
Easley Retail Center - 2,400 SF Available
$16 SF/Yr
4,800 SF

Easley Retail Center - 2,400 SF Available

High-traffic retail space, Easley, SC.

5156 Calhoun Memorial Hwy, Easley, SC 29640
View details
Calhoun Hwy Retail Space
$22 SF/Yr

Calhoun Hwy Retail Space

1660 sq ft Retail Suite Available

5115-5119 Calhoun Memorial Hwy, Easley, SC 29640
View details
Prime Retail Space, Pickens County
Contact for pricing
76,566 SF

Prime Retail Space, Pickens County

High-traffic location, multiple units available

500 Old Greenville Hwy, Clemson, SC 29631
View details
Cedar Square Retail Center
$5 SF/Yr
64,880 SF

Cedar Square Retail Center

Pickens Retail Space Available Now

2700 Gentry Memorial Hwy, Pickens, SC 29671
View details
Easley Retail Center - Main St.
$10 SF/Yr
38,878 SF

Easley Retail Center - Main St.

High-traffic retail space, Easley, SC.

504 Main St, Easley, SC 29640
View details
Clemson Retail Space: 15,214 SF Available
Contact for pricing
44,128 SF

Clemson Retail Space: 15,214 SF Available

High-traffic Clemson retail space, ideal for multiple tenants.

107 Canoy Ln, Clemson, SC 29631
View details
Clemson Retail Space - Tiger Blvd
$22 SF/Yr
1,300 SF

Clemson Retail Space - Tiger Blvd

1300 SF Restaurant Space Available Now!

1067 Tiger Blvd, Clemson, SC 29631
View details
Based on your search, we've compiled 37 Potential Opportunities for your consideration. Besides 17 Active listings in Pickens County, SC, we suggest exploring alternatives. Similar 20 Properties for Sales.

Explore Similar Spaces for Sale in Pickens County, SC

Consider Similar Space for Sale. We found 20 Spaces in Nearby Locations matching your search parameters.

Easley Commercial Land Opportunity
$275,000
2.00 Acres

Easley Commercial Land Opportunity

2-acre commercial land with existing building, development potential.

2625 Farrs Bridge Rd, Easley, SC 29640
View details
Commercial Building on Highway 123
$1,349,990
0.48 Acres

Commercial Building on Highway 123

Commercial building in Clemson with ample parking and high traffic.

990 Tiger Blvd, Clemson, SC 29631
View details
Downtown Easley Retail Opportunity
Contact for pricing

Downtown Easley Retail Opportunity

2,000 SF retail space in downtown Easley, SC.

106 N Pendleton St, Easley, SC 29640
View details
Dollar General Investment Opportunity
$846,720
9,100 SF

Dollar General Investment Opportunity

NNN leased Dollar General with strong operating history.

3711 Farrs Bridge Rd, Easley, SC 29640
View details
Easley Showroom/Office/Warehouse For Sale
$1,400,000
18,000 SF

Easley Showroom/Office/Warehouse For Sale

18,000 SF showroom/office/warehouse in Easley, SC. Owner/user opportunity.

1017 Powdersville Rd, Easley, SC 29642
View details
Prime Location Retail Property
$875,000
8,000 SF

Prime Location Retail Property

Conveniently located retail property off Hwy 123 near downtown Easley.

600 Ross Ave, Easley, SC 29640
View details
Unzoned Land with Restaurant Lease
Contact for pricing
9,000 SF

Unzoned Land with Restaurant Lease

7.48 acres with new restaurant lease in Easley, SC.

1020 Powdersville Rd, Easley, SC 29642
View details

Pickens County, SC Retail properties Leasing Opportunities Market Analysis

Explore Retail properties leasing options in Pickens County, SC with 37 listings featured on our commercial real estate exchange. The current inventory includes 5,505,374,160 square feet of properties with an estimated lease value of $63 SF/Yr.

Estimated lease rates for Retail properties in Pickens County, SC begin at $5 SF/Yr, with an average of $12 SF/Yr and extend to $22 SF/Yr.
List
Map