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    Clemson, SC Commercial Real Estate for Lease

    9 results
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    Downtown Clemson Retail Space Available
    $2,800 / Mo

    Downtown Clemson Retail Space Available

    382 College Ave Unit, Clemson, SC 29631

    Retail space in downtown Clemson, formerly a coffee shop.

    • Prime downtown Clemson location.
    • Approximately 2100 sqf. of finished space.
    • Accessible from Kieth St.
    • Central heating and cooling.
    • Durable brick construction.
    Updated: Dec 30, 2025
    View details
    Retail Space Near Clemson University
    Contact for pricing
    1,233 SF

    Retail Space Near Clemson University

    1390 Tiger Blvd, Clemson, SC 29631

    Publix-anchored retail space with high visibility near Clemson University.

    • Publix‑anchored center for reliable customer draw.
    • Located less than 1‑mile from Clemson University (27,000 students).
    • Excellent visibility on heavily traveled Tiger Boulevard with multiple access points.
    • Strong, diverse tenant mix including restaurants and personal care services.
    • High combined traffic count: 41,200 VPD.
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    Freestanding Restaurant Space Available
    Contact for pricing
    4,029 SF

    Freestanding Restaurant Space Available

    4,029 SF freestanding restaurant with drive-thru in Clemson, SC.

    1071 Tiger Blvd, Clemson, SC 29631
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    Retail/Restaurant Space Near Clemson University
    Contact for pricing
    3,500 SF

    Retail/Restaurant Space Near Clemson University

    Retail/restaurant space with dedicated parking and lake access.

    894 Tiger Blvd, Clemson, SC 29631
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    Mixed-Use Property Near Clemson Campus
    Contact for pricing

    Mixed-Use Property Near Clemson Campus

    Mixed-use property with residential and retail components near Clemson University.

    111 Earle St, Clemson, SC 29631
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    Retail/Restaurant Space Near Clemson University
    Contact for pricing
    1,401 SF

    Retail/Restaurant Space Near Clemson University

    Retail/restaurant spaces available in mixed-use student housing project.

    114 Earle St, Clemson, SC 29631
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    Prime Retail Space, Pickens County
    Contact for pricing
    76,566 SF

    Prime Retail Space, Pickens County

    High-traffic location, multiple units available

    500 Old Greenville Hwy, Clemson, SC 29631
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    Clemson Retail Space: 15,214 SF Available
    Contact for pricing
    44,128 SF

    Clemson Retail Space: 15,214 SF Available

    High-traffic Clemson retail space, ideal for multiple tenants.

    107 Canoy Ln, Clemson, SC 29631
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    Clemson Retail Space - Tiger Blvd
    $22 SF/Yr
    1,300 SF

    Clemson Retail Space - Tiger Blvd

    1300 SF Restaurant Space Available Now!

    1067 Tiger Blvd, Clemson, SC 29631
    View details
    Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 9 Active listings in Clemson, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail Space Near Clemson University
    $21 SF/Yr
    43,000 SF

    Retail Space Near Clemson University

    End-cap retail space with drive-thru potential near Clemson University.

    1085 Old Clemson Hwy, Seneca, SC 29672
    View details
    Office Space Near Clemson
    $4,000 / Mo
    26,136 SF

    Office Space Near Clemson

    Two-level office building suitable for various businesses, near Clemson.

    865 Old Clemson Hwy, Seneca, SC 29678
    View details
    Historic Pendleton Bank Retail Space
    $3,500 / Mo

    Historic Pendleton Bank Retail Space

    Renovated retail space in historic Pendleton Town Square.

    104 Exchange St, Pendleton, SC 29670
    View details
    Historic Building in Pendleton Square
    $3,100 / Mo

    Historic Building in Pendleton Square

    Iconic building in vibrant Pendleton, SC, near Clemson University.

    102 Exchange St, Pendleton, SC 29670
    View details

    Explore Similar Spaces for Sale in Clemson, SC

    Consider Similar Space for Sale. We found 9 Spaces in Nearby Locations matching your search parameters.

    Clemson Multi-Family Investment Opportunity
    Pending
    $1,500,000
    1.00 Acre

    Clemson Multi-Family Investment Opportunity

    Six apartments in three duplexes near Clemson's Calhoun area.

    101 Cochran Rd, Clemson, SC 29631
    View details
    Commercial Building on Highway 123
    $1,349,990
    0.48 Acres

    Commercial Building on Highway 123

    Commercial building in Clemson with ample parking and high traffic.

    990 Tiger Blvd, Clemson, SC 29631
    View details
    Clemson Development Opportunity
    $1,299,774
    7.66 Acres

    Clemson Development Opportunity

    7+ acres zoned for hotel or multifamily development near Clemson.

    76 Hwy W, Clemson, SC 29631
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    Clemson Land for Multifamily Development
    $1,299,774
    7.66 Acres

    Clemson Land for Multifamily Development

    7+ acres in Clemson, SC, ideal for multifamily or hotel development.

    00 76 Hwy, Clemson, SC 29631
    View details
    Medical Office Site Opportunity
    $499,000

    Medical Office Site Opportunity

    Prime location near Clemson University in Patrick Square.

    Chapman Hl Rd, Clemson, SC 29631
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    Land for Medical Office Building
    $499,000

    Land for Medical Office Building

    Land available with approved plans for medical office building.

    105 Chapman Hl Rd, Clemson, SC
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    Clemson Land Parcels Available
    Contact for pricing

    Clemson Land Parcels Available

    Two outparcels available in Clemson, South Carolina.

    608 Issaqueena Trl, Clemson, SC 29631
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    Commercial Building on Highway 123
    $1,349,990

    Commercial Building on Highway 123

    6000 sq ft commercial building with ample parking.

    990 Tiger Blvd, Clemson, SC 29631
    View details
    Clemson Commercial Land - 7.66 Acres
    $1,299,774
    7.66 Acres

    Clemson Commercial Land - 7.66 Acres

    Prime Clemson location, ideal for hotel or multi-family development.

    00 Hwy 76 Hwy, Clemson, SC 29631
    View details

    Clemson, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Clemson, SC with 18 listings featured on our commercial real estate exchange. The current inventory includes 56,628,000 square feet of properties with an estimated lease value of $22 SF/Yr.

    Estimated lease rates for Commercial real estate in Clemson, SC begin at $22 SF/Yr, with an average of $22 SF/Yr and extend to $22 SF/Yr.
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