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Sikeston, MO Retail Properties for Lease

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Sikeston Office Suite For Rent
$3,625 / Mo
2,000 SF

Sikeston Office Suite For Rent

912 S Main St, Sikeston, MO 63801

Recently-built office suite with four offices, bathroom, and kitchenette.

  • High visibility location on Sikeston's busiest corridor.
  • Ready for immediate occupancy with 4 finished offices.
  • Two entrances ideal for businesses with public traffic.
  • Includes a bathroom and kitchenette with refrigerator and table/chairs.
  • Located in a recently‑built (2020) strip center.
Updated: Sep 22, 2025
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Retail Space in Sikeston, MO
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2,900 SF

Retail Space in Sikeston, MO

925-1077 Malone Ave, Sikeston, MO 63801

Retail space available in grocery store anchored shopping center.

  • Grocery store anchored shopping center
  • High traffic count: Over 12,000 vehicles per day
  • Approximately 2,000 students within walking distance
  • Located along E. Malone / Hwy 62
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Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 2 Active listings in Sikeston, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

Explore Retail properties for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Charleston Retail Space - Main Street
Contact for pricing
8,351 SF

Charleston Retail Space - Main Street

High-traffic retail space, 8,351 sq ft.

601 Main St, Charleston, MO 63834
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Charleston Retail or Office Space
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Charleston Retail or Office Space

Retail or office space with excellent visibility and parking.

114 W Commercial St, Charleston, MO 63834
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Retail Space Near Interstate 55
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10,800 SF

Retail Space Near Interstate 55

Retail space in regional shopping hub with interstate access.

258 Siemers Dr, Cape Girardeau, MO 63701
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West Park Mall Medical Office Space
Contact for pricing
79,122 SF

West Park Mall Medical Office Space

Missouri medical office suites for lease

3049 William St, Cape Girardeau, MO 63703
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Explore Similar Spaces for Sale in Sikeston, MO

Consider Similar Space for Sale. We found 8 Spaces in Nearby Locations matching your search parameters.

Sikeston Commercial Property For Sale
$600,000
1.30 Acres

Sikeston Commercial Property For Sale

Income-producing property with commercial spaces and storage units.

2008 N Main St, Sikeston, MO 63801
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Historical Building in Downtown Sikeston
$269,000
6,321 SF

Historical Building in Downtown Sikeston

Two-story historic building in downtown Sikeston, ideal for investors.

112 Front St, Sikeston, MO 63801
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Sikeston Commercial Property For Sale
$650,000
1.28 Acres

Sikeston Commercial Property For Sale

Prime commercial location with high visibility and established business history.

1105 S Main St, Sikeston, MO 63801
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Historic Downtown Sikeston Retail Opportunity
$299,000
14,642 SF

Historic Downtown Sikeston Retail Opportunity

Two-story retail space in historic downtown Sikeston, Missouri.

124 E Front St, Sikeston, MO 63801
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Sikeston Retail Property For Sale
$550,000
1,150 SF

Sikeston Retail Property For Sale

Established family-owned business with high visibility for over 30 years.

1018 Linn St, Sikeston, MO 63801
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Sikeston Car Wash with Expansion Potential
$1,000,000
40,511 SF

Sikeston Car Wash with Expansion Potential

Turnkey car wash with expansion potential in high-demand market.

531 N Main St, Sikeston, MO 63780
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Sikeston Carwash with High Visibility
$1,250,000
40,946 SF

Sikeston Carwash with High Visibility

Turnkey carwash with high traffic, visibility, and recurring revenue.

900 S Main St, Sikeston, MO 63801
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Sikeston Commercial Property with Income
$290,000
4,244 SF

Sikeston Commercial Property with Income

Commercial building, duplex, and storage on 1.22 acres.

101-103 Donald Fulton Dr, Sikeston, MO 63801
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Sikeston, MO Retail properties Leasing Opportunities Market Analysis

Explore Retail properties leasing options in Sikeston, MO with 10 listings featured on our commercial real estate exchange. The current inventory includes 2,642,210,242 square feet of properties with an estimated lease value of $36 SF/Yr.

Estimated lease rates for Retail properties in Sikeston, MO begin at $2 SF/Yr, with an average of $12 SF/Yr and extend to $21 SF/Yr.
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