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    Bluffton, SC
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    Bluffton, SC Office Units for Lease

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    7 properties
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    Office Suites with Highway Frontage
    Updated: Jun 3
    Office Suites with Highway Frontage

    2 Westbury Park Way, Bluffton, SC 29910

    $32 SF/Yr
    3,870 sqft
    2002‑built office property fronting Hwy 278 (Fording Island Road) with 250'+ highway frontage
    2 suites available: 1,790 SF and 3,870 SF (total 5,660 SF)
    Bluffton side of Hwy 278 with easy access to major thoroughfares
    Ample on‑site parking for employees and visitors
    Existing tenant mix includes medical, professional, institutional, and local tenants
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    Highway 170 Retail/Office/Medical Space
    Updated: Nov 21, 2025
    Highway 170 Retail/Office/Medical Space

    Bluffton, SC 29909

    $36.50 SF/Yr
    3,970 sqft
    Excellent visibility directly on Highway 170.
    Located in a brand new development (The Terrace at Okatie Crossings) with diverse tenants.
    Strategic location between Bluffton and Beaufort, near Highway 278 Interchange.
    Suitable for retail, office, or medical use.
    Surrounded by significant residential and commercial growth, including proximity to Sun City.
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    Office Unit with Delivery Access
    Office Unit with Delivery Access

    49 Pennington Dr, Bluffton, SC 29910

    Contact for pricing
    1,250 sqft

    Unit D includes a reception area, six offices, a restroom, and rear doors for deliveries and shipping.

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    Ground-Floor Office Unit
    Ground-Floor Office Unit

    1323 May River Road, Bluffton, SC 29910

    Contact for pricing

    Professional suite with reception, private offices, conference space, restrooms, and kitchenette support areas.

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    New Flex Space For Lease
    New Flex Space For Lease

    5 Kitties Landing Dr, Bluffton, SC

    Contact for pricing
    3,360 sqft 1.42 AC lot

    New construction flex space suitable for office, retail, or warehouse.

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    Class A Office Space
    Class A Office Space

    New Riverside Vlg Wy, Bluffton, SC 29910

    Contact for pricing

    Office space in mixed-use center with retail and residential.

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    Class A Office Space Available
    Class A Office Space Available

    1 Carecore Dr, Bluffton, SC 29910

    Contact for pricing

    LEED Certified office space for lease in Buckwalter Place.

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    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 7 Active listings in Bluffton, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

    Office Units for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office Space with High-End Finishes
    Office Space with High-End Finishes

    386 Spanish Wells Rd, Unit B-3 |, Hilton Head Island, SC 29926

    $3,000/Mo
    2,175 sqft

    Office space featuring high-end finishes in a desirable location.

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    Flex Space with Warehouse
    Flex Space with Warehouse

    61 Schinger Ave, Ridgeland, SC 29936

    Contact for pricing
    1,680 sqft

    Unit 101 pairs administrative offices with a dedicated warehouse area and break room.

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    Mixed Commercial Space Available
    Mixed Commercial Space Available

    46 Old Wild Horse Road, Hilton Head Island, SC 29926

    Contact for pricing
    1,500 sqft

    1,500 sq. ft. space ideal for retail, office, or storage.

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    Ridgeland Office Space Available
    Ridgeland Office Space Available

    122 Riverwalk Blvd, Ridgeland, SC 29936

    Contact for pricing
    2,600 sqft

    Office space for sublease in well-maintained building.

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    Similar Spaces for Sale in Bluffton, SC

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    Office-Showroom Warehouse Building
    Office-Showroom Warehouse Building

    29 Kitties Landing Road, Bluffton, SC 29910

    $2,475,000
    10,000 sqft 1.00 AC lot

    Metal-frame office, showroom, and warehouse building with four roll-up doors and full HVAC on about one acre.

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    Class A Office Building Space
    Class A Office Building Space

    1 Carecore Drive, Bluffton, SC 29910

    Contact for pricing
    30,065 sqft

    Office space for sale in Buckwalter Place, Bluffton.

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    Class A Office/Warehouse Complex
    Class A Office/Warehouse Complex

    3095 Soperton Dr, Bluffton, SC 29910

    Contact for pricing
    5,562 sqft

    Luxury office and warehouse space built in 2023.

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    Medical Office Suite
    Medical Office Suite

    4 Okatie Center Boulevard South, Okatie, SC 29909

    Contact for pricing
    3,075 sqft

    Medical office suite available in Okatie Center, located just off Hwy 170 near the Hwy 278 interchange.

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    First-Floor Office Unit
    First-Floor Office Unit

    1323 May River Road, Bluffton, SC 29910

    Contact for pricing

    Downtown office suite with reception, conference room, private offices, restrooms, storage, and kitchenette.

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    Charming Cottage in Old Town
    Charming Cottage in Old Town

    5728 Guilford Place, Bluffton, SC 29910

    Contact for pricing

    Unique commercial space in the heart of Old Town Bluffton.

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    Retail Buildings with Drive-Through
    Retail Buildings with Drive-Through

    280 Old Bridge Drive, Bluffton, SC 29910

    Contact for pricing

    One building offers drive-through availability, while the other provides retail and office space.

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    Bluffton, SC Office Units Market Trends and Statistics

    Explore Office Units leasing options in Bluffton, SC with 7 listings featured on our commercial real estate exchange. The current inventory includes 12,450 square feet of properties with an estimated lease value of $68.50.

    Estimated lease rates for Office Units in Bluffton, SC begin at $32 SF/Yr, with an average of $34.25 SF/Yr and extend to $36.50 SF/Yr.
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    Most Searched ZIP Codes in Bluffton, SC

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    • 29909

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