Syracuse, NY Office Units for Rent & Lease

Updated: Aug 10

Retail Space with Central Air

4455A E Genesee Street, Syracuse, NY 13214

$1,300/Mo

14,760 sqft 0.86 AC lot

14,760‑square‑foot retail property on a 0.86‑acre parcel
Multiple listed use options, including retail, office, service, gallery, studio, and take‑out food service
Central air conditioning and natural gas forced‑air heating
Public water and public sewer
Built in 1963 with a flat roof

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Updated: Jul 29

Creative Space With Roof Access

308 W Genesee St, Syracuse, NY 13202

$10,000/Mo

11,220 sqft

Entire second floor with stairwell included
11,220 square feet of available space
Shell condition requiring full build‑out
Large windows with strong street exposure
Roof access suitable for an outdoor area

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Creative Office/Retail Space

112 Wilkinson Street, Syracuse, NY 13204

$8 SF/Yr

12,500 sqft

Second-floor creative office and retail space offers natural light and a flexible blank-canvas layout.

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Furnished Office Units with Parking

580 South Salina Street, Syracuse, NY 13202

$11.67-$14 SF/Yr

3,600 sqft

CBD-zoned office premises with optional furniture, basement storage, and exterior signage opportunities.

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Office Unit with Outdoor Patio

Dewitt, NY 13057

$1,850/Mo

950 sqft

One-story professional office space with conference room access, shared restrooms, and convenient parking.

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Corner Office Unit

447 East Washington Street, Syracuse, NY 13202

$3,000/Mo

Ground-level commercial space combines an adaptable open area with separate private and public restrooms.

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Medical Office Suite with Exam Rooms

3400 Vickery Road, Syracuse, NY 13212

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4,196 sqft

Suite C offers a mix of open space, private offices, and exam rooms for healthcare use.

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Medical-Convertible Office Suite

6567 Kinne Rd, Syracuse, NY 13214

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8,400 sqft

Office space with multiple offices, conference rooms, and private bathrooms, supported by shared-building water for possible medical use.

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Flex Warehouse with Office

209 Factory Ave, Syracuse, NY 13208

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6,615 sqft 0.27 AC lot

Flex facility includes 3,200 SF of Class A office space and 3,415 SF warehouse with two automatic overhead doors.

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Flex Space with Loading Docks

530 State Fair Blvd, Syracuse, NY 13204

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15,000 sqft

Adaptable flex space with office area, three-phase power, dock access, and sprinkler protection.

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Office Suite with Large Window Lines

2804-2806 Court St, Syracuse, NY 13208

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1,225 sqft

First-floor office space for lease with strong natural light and window lines in a two-floor layout.

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Second-Floor Office Suite

550 Westcott Street, Syracuse, NY 13210

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1,300 sqft

Bright second-floor suite with front and rear windows, flexible layout, luxury vinyl flooring, and freshly painted interiors.

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Syracuse Flex Space For Rent

4601 Nixon Park Drive, Syracuse, NY

$5.25 SF/Yr

62,000 sqft

Flex/industrial/office space near Route 175, Syracuse, NY.

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Class A Suburban Office Park

200 Salina Meadows Pkwy, Syracuse, NY

$18 SF/Yr

44,730 sqft

Class A office space for rent in Syracuse, New York.

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Class A Suburban Office Park

220 Salina Meadows Pkwy, Syracuse, NY

$18 SF/Yr

44,730 sqft

Class A office space for rent in Syracuse, New York.

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Class A Suburban Office Park

231 Salina Meadows Pkwy, Syracuse, NY

$18 SF/Yr

53,992 sqft

Class A office space available for rent in Syracuse, NY.

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Office Units Near Interstate Access

1045 James St, Syracuse, NY 13203

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3,600 sqft

Office space is positioned near restaurants, retail shops, banks, and hotels.

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First-Floor Office Suite

2804 Court Street, Syracuse, NY 13206

$12 SF/Yr

First-level office space with a private restroom and multiple offices, featuring windows in nearly every room.

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Class A Office Suite

6702 Buckley Rd, Syracuse, NY 13212

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1,760 sqft

Well-maintained, newly built-out office suite with perimeter offices, waiting/reception, break room, and double conference room.

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Renovated Office Space For Lease

207 Pine St, Syracuse, NY 13210

$1,250/Mo

0.75 AC lot

Recently renovated office space available for lease in convenient location.

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Built-Out Office Units

300 South State Street, Syracuse, NY 13202

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Sublease office space with private offices, conference rooms, kitchen facilities, and workstation capacity.

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Two-Story Office Suites

231 Salina Meadows Pkwy, Syracuse, NY 13212

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2,932 sqft

Second-floor office suites available, with option to combine for a larger footprint.

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Modern Medical and Office Space

1304 Buckley Road, Syracuse, NY 13212

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33,548 sqft

Three floors of modern medical and office space for rent.

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Syracuse Office Space Available

208 S Warren St, Syracuse, NY

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2,600 sqft 0.32 AC lot

Office space available for rent in Syracuse, New York.

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Syracuse, NY Office Units Lease Rates & Market Statistics

Explore 39 Office Units for lease in Syracuse, NY on Realmo, a commercial real estate exchange covering the Syracuse area. The current inventory totals 399,419 square feet of properties — an average of ~10,250 SF per listing.

Office Units lease rates in Syracuse range from $1.06 SF/Yr at the entry level to $23.37 SF/Yr at the top of the market, averaging $12.73 SF/Yr. That's a 22x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $12.73 SF/Yr is 57% below the New York state average of $29.47 SF/Yr.

Syracuse accounts for 54% of the 72 office units currently available across Onondaga County, where nearby markets include East Syracuse and Liverpool. Office Units make up 71% of the 55 Office Spaces currently for lease in Syracuse, with asking rates averaging $12.73 SF/Yr — 11% below the citywide Office Spaces average of $14.34 SF/Yr. Tenants comparing options may also consider Office buildings (14 listings) and Medical Office Space (6 listings) elsewhere in the Syracuse market.