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    Portsmouth, NH Office Space for Lease

    51 results
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    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    500 Maplewood Ave, Portsmouth, NH 03801

    Versatile office space in Portsmouth, accessible from city or bypass.

    • Highly accessible location just off Route 1 Bypass in Portsmouth.
    • Versatile first‑floor layout with open showroom/bullpen, 8 private offices, and 2 conference/team rooms.
    • Includes a kitchen and 2 restrooms.
    • Additional storage rooms on the first floor.
    • Large (3,921 sf) unfinished second‑floor space suitable for storage or future office build‑out.
    Last Update: Sep 27
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    Prime Portsmouth Commercial Space Available
    Contact for pricing
    4,792 SF

    Prime Portsmouth Commercial Space Available

    1290 Woodbury Ave, Portsmouth, NH 03801

    1,470 SF office/retail space in high-traffic Portsmouth location.

    • High‑visibility location on Woodbury Avenue in a high‑traffic commercial area.
    • Easy access to Interstate 95 and proximity to shopping plazas (Market Basket, Whole Foods).
    • Flexible 1,470 SF interior layout easily reconfigured for various professional, medical, or retail uses.
    • Ample on‑site parking for clients and employees.
    • Abundant natural light and 10' ceilings creating a bright, welcoming atmosphere.
    Last Update: Nov 16
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant downtown location.
    10 Vaughan St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant, walkable downtown location.
    10 Vaughan St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suites Available
    Contact for pricing

    Downtown Portsmouth Office Suites Available

    Move-in-ready office suites in a vibrant downtown location.
    10 Vaughan St, Portsmouth, NH 03801
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    Prime Portsmouth Commercial Space Available
    Contact for pricing
    174,240 SF

    Prime Portsmouth Commercial Space Available

    High-traffic location suitable for retail, medical, restaurant, or office use.
    750 Lafayette Rd, Portsmouth, NH 03801
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    Portsmouth Professional Office Space Available
    Contact for pricing
    1,500 SF

    Portsmouth Professional Office Space Available

    Individual offices for health practitioners, flexible lease terms, utilities included.
    4 Greenleaf Woods Dr, Portsmouth, NH 03801
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    Versatile Commercial Space on Lafayette Road
    Contact for pricing
    174,240 SF

    Versatile Commercial Space on Lafayette Road

    Adaptable Portsmouth space suitable for medical, retail, restaurant, or office.
    750 Lafayette Rd, Portsmouth, NH 03801
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    Portsmouth Office Space For Lease
    Contact for pricing
    48,787 SF

    Portsmouth Office Space For Lease

    Versatile office space in Portsmouth, accessible from city or bypass.
    500 Mapplewood Ave, Portsmouth, NH 03801
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    Downtown Portsmouth Office For Lease
    Contact for pricing

    Downtown Portsmouth Office For Lease

    Single office in downtown Portsmouth with utilities included. Available 2025.
    33 Deer St, Portsmouth, NH 03801
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    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    8,202 SF Office, Prime Location
    500 Maplewood Ave, Portsmouth, NH 03801
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    Class A Office Space for Lease
    $12 SF/Yr
    62,322 SF

    Class A Office Space for Lease

    Modern, 11,412 SF Executive Office Suite
    300 Constitution Ave, Portsmouth, NH 03801
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    Office Space Near Downtown Portsmouth
    $19 SF/Yr
    10,244 SF

    Office Space Near Downtown Portsmouth

    Office spaces with natural light and convenient location near I-95.
    135 Commerce Way, Portsmouth, NH 03801
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    Class A Office Park Space
    $18 SF/Yr
    2,000 SF

    Class A Office Park Space

    Amenity-rich, ENERGY STAR certified office space for rent.
    1 New Hampshire Ave, Portsmouth, NH
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    Class A Office/Retail Space
    $32 SF/Yr
    2,325 SF

    Class A Office/Retail Space

    First-floor office/retail space in a Gold LEED certified building.
    12-12 Portwalk Pl, Portsmouth, NH
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    Class A Office Space Available
    $18 SF/Yr
    16,027 SF

    Class A Office Space Available

    Flexible office suites with modern amenities and ample parking.
    273 Corporate Dr, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    $18 SF/Yr

    Downtown Portsmouth Office Space Available

    Second-floor office space in Vaughan Mall, downtown Portsmouth.
    10 Vaughan Mall St, Portsmouth, NH 03801
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    Versatile Studio Space For Lease
    $1,500 /Mo

    Versatile Studio Space For Lease

    Studio/flex space near Pease International Tradeport, Portsmouth, NH.
    282 Corporate Dr, Portsmouth, NH 03801
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    Renovated Office Space For Lease
    $450 /Mo
    165 SF

    Renovated Office Space For Lease

    Newly renovated office condominium in medical park, convenient location.
    230 Lafayette Rd, Portsmouth, NH 03801
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    Economical Office and Warehouse Space
    $12 SF/Yr
    2,539 SF

    Economical Office and Warehouse Space

    Flexible office and warehouse space near major routes.
    200 International Dr, Portsmouth, NH 03801
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    Turnkey Penthouse Executive Office Suite
    $35 SF/Yr
    3,921 SF

    Turnkey Penthouse Executive Office Suite

    Exclusive penthouse office suite with private elevator access and six offices.
    30 Penhallow St, Portsmouth, NH 03801
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    Downtown Rollinsford Office/Retail Space
    $2,500 /Mo

    Downtown Rollinsford Office/Retail Space

    Office/retail space in historic downtown Rollinsford, near Dover and Somersworth.
    82 Front St, Portsmouth, NH 03869
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    Tradeport Office Space For Lease
    $12 SF/Yr

    Tradeport Office Space For Lease

    Office space available for lease with flexible floor plans.
    112 Corporate Dr, Portsmouth, NH 03801
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    Office or Medical Office Space
    $16 SF/Yr
    2,027 SF

    Office or Medical Office Space

    Office or medical space in Portsmouth's Pease Tradeport.
    14 Manchester Sq, Portsmouth, NH 03801
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    Portsmouth, NH Office space Leasing Opportunities Market Analysis

    Explore Office space leasing options in Portsmouth, NH with 64 listings featured on our commercial real estate exchange. The current inventory includes 8,089,484,040 square feet of properties with an estimated lease value of $579 /Mo.

    Estimated lease rates for Office space in Portsmouth, NH begin at $10 SF/Yr, with an average of $22 SF/Yr and extend to $85 SF/Yr.
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    Browse Office space for Lease Near Portsmouth, NH

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    Most Searched ZIP Codes in Portsmouth, NH

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