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    Saint Charles, MO Office Units for Lease

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    Saint Louis, MO Louis, MO Kansas City, MO
    16 results
    Office Space in Historic Building
    $1,200/Mo
    7,318 SF

    Office Space in Historic Building

    Saint Charles, MO 63301

    Move-in ready office suites with amenities in St. Charles.

    • Prime downtown St. Charles location with quick access to 5th Street, Main Street, Lindenwood University, and Highways 70 and 370.
    • Move‑in ready office suite (30' x 20') suitable for three desks and one private office.
    • Convenient accessible entry and parking right outside the door.
    • Included amenities: 24/7 digital keypad access, reception area, small conference room, Internet & Wi‑Fi, dedicated mailbox, cleaning service, water filtration system, and security cameras.
    • Historic building with renovated office spaces.
    Updated: Mar 10
    View details
    Move-in Ready Office Space
    $500/Mo

    Move-in Ready Office Space

    Saint Charles, MO 63304

    Full service office space with modern amenities included in rent.

    • All‑inclusive rent: Includes heat, electricity, trash, Wi‑Fi, kitchenette, and conference room use.
    • Move‑in ready office with recent renovations: new carpet, paint, lighting, interior and exterior updates.
    • Convenient location: Ample parking and easy access to Hwy 364 and 94.
    • Corner unit on the 1st floor with large windows providing natural light.
    • Access to atrium space with tables and outdoor seating.
    Updated: Dec 16, 2025
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    St Charles Lower-Level Office Space
    $700/Mo

    St Charles Lower-Level Office Space

    660 SF office space with utilities and Wi-Fi included.

    Saint Charles, MO 63304
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    Westgate 200 Available For Lease
    $5 SF/Yr
    86,800 SF

    Westgate 200 Available For Lease

    86,800 SF divisible space with office and showroom.

    3817-3841 Millstone Parkway, Saint Charles, MO 63301
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    St. Charles Retail/Office Space
    $22 SF/Yr
    31,716 SF

    St. Charles Retail/Office Space

    Retail and office spaces available in high-traffic St. Charles location.

    3910-3930 South Old Highway 94, Saint Charles, MO 63304
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    Historic Building Office Suites Available
    $14 SF/Yr
    1,961 SF

    Historic Building Office Suites Available

    Well-maintained office suites in historic building near courthouse.

    300 N Main St, Saint Charles, MO
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    Stand Alone Office For Rent
    $15 SF/Yr
    1,377 SF

    Stand Alone Office For Rent

    1,377 SF stand-alone office space remodeled in 2023.

    1518 Caulks Hill Rd, Saint Charles, MO
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    Professional Office Space Available
    Contact for pricing
    598 SF

    Professional Office Space Available

    Office space with excellent highway exposure and convenient location.

    2480 Executive Dr, Saint Charles, MO
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    Office Space in Regions Bank
    $162 SF/Yr

    Office Space in Regions Bank

    Lower level office space with nearby amenities for rent.

    Saint Charles, MO 63303
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    Office Space in Saint Charles
    Contact for pricing
    3,500 SF

    Office Space in Saint Charles

    Single tenant office space available for rent, 3,500 SqFt.

    2010 Bluestone Dr, Saint Charles, MO 63303
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    Mixed-Use Property in Riverfront District
    Contact for pricing

    Mixed-Use Property in Riverfront District

    Retail, office, and warehouse space in entertainment district.

    1735 S River Rd, Saint Charles, MO 63303
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    Office Spaces Available For Rent
    Contact for pricing
    814 SF

    Office Spaces Available For Rent

    Office spaces ranging from 180 to 814 SqFt available.

    1811 Sherman Dr, Saint Charles, MO 63303
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    Office Space For Lease
    $24 SF/Yr

    Office Space For Lease

    Office space available for lease in St. Charles, MO.

    Saint Charles, MO 63301
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    Historical District Retail/Office Space
    Contact for pricing
    550 SF

    Historical District Retail/Office Space

    550 SF suite in St. Charles Historical District.

    Saint Charles, MO 63301
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    Fountainview Plaza Retail Opportunity
    Contact for pricing

    Fountainview Plaza Retail Opportunity

    Retail spaces in a densely populated St. Charles neighborhood.

    2633 Muegge Rd, Saint Charles, MO 63303
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    Office Space with Ample Parking
    Contact for pricing
    1,685 SF

    Office Space with Ample Parking

    Office space for rent with easy highway access and parking.

    205 N 5 St, Saint Charles, MO
    View details
    Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 16 Active listings in Saint Charles, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Explore Office Units for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office Building with Available Spaces
    $19 SF/Yr
    2,500 SF

    Office Building with Available Spaces

    Office building for lease in high-traffic area with parking.

    St Peters, MO
    View details
    Earth City Office Space Available
    $12 SF/Yr
    8,000 SF

    Earth City Office Space Available

    Office space featuring private offices, conference rooms, and ample parking.

    4101 Rider Trail N, Earth City, MO
    View details
    Class A Office Space Available
    $21 SF/Yr
    18,434 SF

    Class A Office Space Available

    Plug & play office space for sublease through March 2028.

    3300 Rider Trail S, Earth City, MO
    View details
    Retail and Office Space Available
    Contact for pricing
    4,020 SF

    Retail and Office Space Available

    Retail and office spaces available in St. Peters, Missouri.

    915 Jungermann Rd, St Peters, MO 63376
    View details

    Explore Similar Spaces for Sale in Saint Charles, MO

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    High-Visibility Parcel Near Lindenwood University
    $350,000
    1,146 SF

    High-Visibility Parcel Near Lindenwood University

    Rare opportunity: 1,146 SF building near a signalized corner.

    Saint Charles, MO 63301
    View details
    High-Visibility Corner Parcel For Sale
    $450,000
    1,350 SF

    High-Visibility Corner Parcel For Sale

    Corner parcel suitable for redevelopment, retail, or auto sales.

    212 S Kingshighway, Saint Charles, MO 63301
    View details
    High-Visibility Commercial Parcel Available
    $200,000
    1,506 SF

    High-Visibility Commercial Parcel Available

    Commercial parcel suitable for redevelopment, office, or retail.

    Saint Charles, MO 63301
    View details
    Historic Main Street Storefront Opportunity
    $275,000
    864 SF

    Historic Main Street Storefront Opportunity

    Charming brick storefront in vibrant, high-traffic historic district.

    Saint Charles, MO 63301
    View details
    Main Street Mixed-Use Building
    $750,000
    0.16 Acres

    Main Street Mixed-Use Building

    Multi-story building with restaurant, retail, office, and residential potential.

    138 N Main St, Saint Charles, MO
    View details

    Saint Charles, MO Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Saint Charles, MO with 16 listings featured on our commercial real estate exchange. The current inventory includes 404,193,240 square feet of properties with an estimated lease value of $15 SF/Yr.

    Estimated lease rates for Office Units in Saint Charles, MO begin at $1.97 SF/Yr, with an average of $7 SF/Yr and extend to $14 SF/Yr.
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    Most Searched ZIP Codes in Saint Charles, MO

    • 63303
    • 63301
    • 63304

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