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    Saint Charles, MO Office Spaces for Sale

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    14 properties
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    Historic Office Building
    Updated: Sep 12
    Historic Office Building

    Saint Charles, MO 63301

    $850,000
    0.17 AC lot
    Approximately 2,600 SF designated historic office building
    Built in 1890 with brick construction and wood flooring
    Main level offers four office/work spaces, kitchen, and half bath
    Upper level includes three additional spaces, kitchenette, and half bath
    Walk‑out basement provides additional storage or flexible‑use space
    View details
    Temperature-Controlled Flex Space
    Updated: Jun 2
    Temperature-Controlled Flex Space

    Saint Charles, MO 63303

    $950,000
    0.79 AC lot
    7,150 SF office/warehouse on 0.79 acres
    I‑1 Light Industrial zoning
    11' to 12' 6" clear height in warehouse
    One 10x12 loading dock and 1 drive‑in door
    600Amp 3 Phase Electric
    View details
    Freestanding Brick Medical Office
    Freestanding Brick Medical Office

    Saint Charles, MO 63303

    $2,450,000
    0.77 AC lot

    Occupied medical office property with a durable brick exterior, dedicated parking, and access to regional highways.

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    See hot listings in Saint Charles

    Scored against comparables nationwide. These are worth a look.

    Scored against comparables nationwide. These are worth a look.

    Cap Rate available after sign in
    Est. NOI available after sign in
    Local Demand available after sign in
    Flex Space with Clear-Span Warehouse
    Flex Space with Clear-Span Warehouse

    Saint Charles, MO 63303

    Contact for pricing
    5,000 sqft

    Two connected commercial suites combine refurbished offices with climate-controlled warehouse areas and rear storage space.

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    Office Suite with Bullpen
    Office Suite with Bullpen

    918-924 Hemsath Rd, Saint Charles, MO 63303

    Contact for pricing
    1,560 sqft

    Flexible professional workspace includes a private office, kitchenette, restroom, and dedicated storage.

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    Two-Story Office Building
    Two-Story Office Building

    Saint Charles, MO 63303

    Contact for pricing
    9,200 sqft

    Updated multi-level office property with highway exposure, monument signage, and flexible floor-by-floor configuration.

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    Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads
    Two-Story Office Building
    Two-Story Office Building

    Saint Charles, MO 63301

    Contact for pricing
    8,884 sqft

    Two-story office building with bullpens, multiple offices, and conference space, totaling 8,884 sf.

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    Flex Space with Data Center
    Flex Space with Data Center

    Saint Charles, MO 63301

    Contact for pricing
    64,000 sqft 4.51 AC lot

    Warehouse and office improvements with loading capacity and direct access from Hwy 370.

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    Free-Standing Medical Office Building
    Free-Standing Medical Office Building

    11 Garvey Pkwy, Saint Charles, MO 63303

    Contact for pricing
    6,676 sqft

    Free-standing brick medical office building built in 2005 with 32 parking spaces and 100% occupied long-term medical lease.

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    Professional Office Suite
    Professional Office Suite

    Saint Charles, MO 63303

    $199,500

    Flexible office layout with collaborative workspace, private rooms, kitchenette, restroom, and dedicated storage.

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    Masonry Office Building with Parking
    Masonry Office Building with Parking

    Saint Charles, MO 63301

    Contact for pricing
    39,344 sqft 2.46 AC lot

    Move-in ready masonry office building offers exterior access to both finished levels and abundant on-site parking.

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    Multi-Tenant Professional Office Building
    Multi-Tenant Professional Office Building

    Saint Charles, MO 63303

    Contact for pricing
    14,015 sqft

    Professional office building with parking and a 1,250-square-foot space available in a commercial retail restaurant area.

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    Class A Office/Flex Building
    Class A Office/Flex Building

    500 Fountain Lakes Blvd, Saint Charles, MO 63301

    Contact for pricing

    Office/flex building with heavy power and potential for warehouse conversion.

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    Mixed-Use Building with Rental Units
    Mixed-Use Building with Rental Units

    Saint Charles, MO 63301

    Contact for pricing
    2,852 sqft

    Includes 2 renovated second-floor rental units and a main-level commercial space leased at $2,614 monthly plus NNN.

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 14 Active listings in Saint Charles, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 58 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Updated Two-Level Office Building
    Updated Two-Level Office Building

    1276 Jungermann Road, St Peters, MO 63376

    $550,000
    0.17 AC lot

    Professional office property with multiple private workspaces, conference facilities, reception areas, and separate lower-level access.

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    Multi-Suite Office Property
    Multi-Suite Office Property

    F-1405 Jungermann Rd, Saint Peters, MO 63376

    $300,000
    7,856 sqft

    Five-suite office building with available end-cap space and dedicated areas suited to fitness, medical, or professional office use.

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    Updated Office Building with Reception
    Updated Office Building with Reception

    1276 Jungermann Rd, Saint Peters, MO 63376

    $550,000

    Office building updated in 2025, offering a main-level lobby, conference room, and lower level with private entrance.

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    Multi-Tenant Retail Office Building
    Multi-Tenant Retail Office Building

    1236 Jungermann Rd, St Peters, MO 63376

    Contact for pricing

    Multi-tenant retail and office building offering flexible suite sizes with generous on-site parking.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land Near I-64/40
    Commercial Land Near I-64/40

    6147 S Highway 94, Weldon Spring, MO 63304

    $750,000
    2.01 AC lot

    Future commercial zoning outlines retail, office, hospitality, entertainment, and other potential uses.

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    Commercial Land with Development Plan
    Commercial Land with Development Plan

    1.33 acres Siedentop Road, Weldon Spring, MO 63304

    $405,545
    1.33 AC lot

    Undeveloped commercial parcel with planned OLD TOWN zoning supporting retail, office, hospitality, and other listed uses.

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    Commercial Development Land Parcel
    Commercial Development Land Parcel

    6219 S Highway 94, Weldon Spring, MO 63304

    $579,348
    1.90 AC lot

    1.9-acre parcel with utilities and strong highway frontage, positioned for future commercial zoning consideration.

    View details
    Commercial Land Near I-64/40
    Commercial Land Near I-64/40

    1.44 acres Weldon Spring Road, Weldon Spring, MO 63304

    $250,906
    1.44 AC lot

    Commercially zoned land with a corner position and access to I-64/40, Hwy 94, and Hwy K.

    View details

    Off-Market Properties in Saint Charles, MO

    Consider similar Off-Market properties in Saint Charles, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    609 1st Capitol Dr
    OFFICE BUILDING

    609 1st Capitol Dr, Saint Charles, MO 63301-2727

    Estimated value:
    $105,000
    800 sqft 0.06 AC lot
    View details
    1112 1st Capitol Dr
    OFFICE BUILDING

    1112 1st Capitol Dr, Saint Charles, MO 63301-2769

    Estimated value:
    $550,000
    5,530 sqft 0.28 AC lot
    View details
    3451 Harry S Truman Blvd
    OFFICE BUILDING

    3451 Harry S Truman Blvd, Saint Charles, MO 63301-4047

    Estimated value:
    $5,065,000
    42,528 sqft 5.06 AC lot
    View details
    617 Main St
    OFFICE BUILDING

    617 Main St, Saint Charles, MO 63301-3440

    Estimated value:
    $410,000
    2,646 sqft 0.14 AC lot
    View details
    Randolph St
    OFFICE BUILDING

    Randolph St, Saint Charles, MO 63301

    Estimated value:
    $13,855,000
    139,056 sqft 12.13 AC lot
    View details
    1014 1st Capitol Dr
    OFFICE BUILDING

    1014 1st Capitol Dr, Saint Charles, MO 63301-2736

    Estimated value:
    $115,000
    900 sqft 0.05 AC lot
    View details
    2270 Bluestone Dr
    OFFICE BUILDING

    2270 Bluestone Dr, Saint Charles, MO 63303-5981

    Estimated value:
    $390,000
    3,000 sqft 0.48 AC lot
    View details
    2111 Collier Corporate Pkwy
    OFFICE BUILDING

    2111 Collier Corporate Pkwy, Saint Charles, MO 63303-6707

    Estimated value:
    $295,000
    2,000 sqft 0.24 AC lot
    View details
    2138 1st Capitol Dr
    MEDICAL BUILDING

    2138 1st Capitol Dr, Saint Charles, MO 63301-5804

    Estimated value:
    $510,000
    5,016 sqft 0.48 AC lot
    View details
    2633 Clay St
    OFFICE BUILDING

    2633 Clay St, Saint Charles, MO 63301-2525

    Estimated value:
    $940,000
    6,970 sqft 1.28 AC lot
    View details

    Saint Charles, MO Office Spaces Market Trends and Statistics

    Explore 72 office spaces for sale in Saint Charles, MO, showcased through 14 active listings on our real estate platform. These investment opportunities span a total of 151,531 square feet of properties for sale, with an estimated market value of $4,449,500.

    Sale prices for office properties in Saint Charles, MO start at $199,500, averaging $1,112,375, and reaching up to $2,450,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 39
    Office buildings 13
    Medical Office Space 6

    Demographics Overview

    Population 142K
    Population Growth (5Y) +1.4%
    Median Household Income $97,683
    College Educated 47.2%

    High-Yield Neighborhoods for Investment

    Identify Saint Charles submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63301 $850K
    63303 $1.2M

    Listings Trend

    New vs delisted commercial listings in St. Charles County

    New Delisted

    Total CRE Inventory on Market (SF)

    How Realmo verifies these figures

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    Most Searched ZIP Codes in Saint Charles, MO

    • 63303
    • 63301
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