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    Saint Charles, MO

    Saint Charles, MO Commercial Real Estate for Lease

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    67 properties
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    Connected Office Suites
    Updated: Sep 23
    Connected Office Suites

    Saint Charles, MO 63304

    $430/Mo
    Suite 202 measures 349 SF; Suite 203 measures 224 SF; combined area is 573 contiguous SF
    Suites can be leased separately or together and connect by a private hallway
    Full‑service offering includes heat, electricity, trash, Wi‑Fi, kitchenette, and conference room use
    Recent updates include flooring, paint, lighting, and interior and exterior renovations
    Large windows, common‑area bathrooms on each floor, and atrium seating
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    Private Office Suites
    Updated: Jul 22
    Private Office Suites

    Saint Charles, MO 63301

    $500/Mo
    0.23 AC lot
    Suites 203 and 204 offer approximately 13' x 11' of private, lockable office space
    High‑speed internet and Wi‑Fi included
    24/7 secure building access with security cameras
    Dedicated mailbox and business address provided
    Renovated 1920 brick office building
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    New Construction Retail Space
    New Construction Retail Space

    Saint Charles, MO 63301

    $2,850/Mo
    1.25 AC lot

    White-box delivery offers flexible space for customized retail or office buildouts.

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    Lower-Level Office Units
    Lower-Level Office Units

    Saint Charles, MO 63301

    $667/Mo
    800 sqft

    Lower-level units in a retail center are identified for office, storage, or BLDR office use.

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    Office Unit with Kitchenette
    Office Unit with Kitchenette

    Saint Charles, MO 63301

    $1,400/Mo
    0.16 AC lot

    Compact office setup with a kitchenette, bathroom area, and a setting suited to minimal foot traffic.

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    Medical Office Space with Operatories
    Medical Office Space with Operatories

    Saint Charles, MO 63303

    $19 SF/Yr
    1.59 AC lot

    Clinical layout includes reception, private offices, lab rooms, storage, patient amenities, and zoned HVAC.

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    Office Space Near I-70
    Office Space Near I-70

    190 Spring Drive, Saint Charles, MO 63303

    $10 SF/Yr
    7,584 sqft

    7,584 SF office space with convenient highway access.

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    Multi-Tenant Brick Office Building
    Multi-Tenant Brick Office Building

    Saint Charles, MO 63303

    $12 SF/Yr
    14,015 sqft

    Well-maintained all-brick office building offers an updated, 1,550 SF suite with separate at-grade entrances.

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    Professional Office Space
    Professional Office Space

    Saint Charles, MO 63303

    $15 SF/Yr
    11,160 sqft

    Professional office space for lease with ample parking and strong exposure to Hwy 94.

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    Highway-Frontage Shopping Center
    Highway-Frontage Shopping Center

    Saint Charles, MO 63303

    $9-$10.50 SF/Yr
    16,000 sqft

    Multi-suite retail center with flexible commercial space near two major highways.

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    Fenced Flex Space with Drive-In Doors
    Fenced Flex Space with Drive-In Doors

    7 Governor Dr, Saint Charles, MO 63301

    Contact for pricing
    6,000 sqft

    Secure, fully fenced property combines office space, storage, and drive-in access.

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    HVAC-Controlled Flex Space
    HVAC-Controlled Flex Space

    Saint Charles, MO 63303

    Contact for pricing
    2,500 sqft

    Clean, temperature-controlled suite with adaptable office-warehouse functionality and three-phase power availability.

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    Newly Renovated Medical Office Space
    Newly Renovated Medical Office Space

    Saint Charles, MO 63303

    Contact for pricing
    2,698 sqft

    Newly renovated two-story entrance lobby anchors office suites with conference and kitchen amenities.

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    Professional Office Suite with Bullpen
    Professional Office Suite with Bullpen

    918-924 Hemsath Rd, Saint Charles, MO 63303

    Contact for pricing
    1,560 sqft

    Business-park space combines collaborative work areas with private office and support amenities.

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    Second-Floor Office with 11 Offices
    Second-Floor Office with 11 Offices

    Saint Charles, MO 63301

    Contact for pricing
    3,500 sqft

    Second-floor office space above Llewelyn’s Pub with 11 offices, a bullpen area, and lot and street parking.

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    Retail Space with Highway Visibility
    Retail Space with Highway Visibility

    Saint Charles, MO 63301

    Contact for pricing
    1,000 sqft

    Retail space with 1,000 to 1,700 SF available, positioned for strong highway visibility and ample on-site parking.

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    Two-Story Office Building
    Two-Story Office Building

    Saint Charles, MO 63303

    Contact for pricing
    9,200 sqft

    Updated professional space offers flexible floor configurations, dedicated parking, signage, and access to multiple regional highways.

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    Second-Floor Office Unit
    Second-Floor Office Unit

    Saint Charles, MO 63301

    Contact for pricing
    675 sqft

    Office suite with a private room, open workspace, kitchenette, and dedicated access.

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    Retail Suite in Retail/Office Building
    Retail Suite in Retail/Office Building

    4500-4520 Central School Rd, Saint Charles, MO 63304

    Contact for pricing
    750 sqft

    750-square-foot space available across from Hollenbeck Elementary School on Central School Road.

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    Suite 105 Office Suite
    Suite 105 Office Suite

    Saint Charles, MO 63301

    Contact for pricing
    1,275 sqft

    Full-service lease Suite 105 in a C-2 zoned, two-story multi-tenant office building with ample parking.

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    Office Unit Near Retail
    Office Unit Near Retail

    Saint Charles, MO 63301

    Contact for pricing
    3,000 sqft

    Office space positioned near retail, restaurants, and other offices with access to nearby regional highways.

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    Turn-Key Dental Office Suite
    Turn-Key Dental Office Suite

    Saint Charles, MO 63303

    Contact for pricing
    2,880 sqft

    Updated dental office with five treatment chairs, waiting and reception area, and accessible restroom plus employee shower.

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    Flex Building with Outdoor Storage
    Flex Building with Outdoor Storage

    261 Hughes Ln, Saint Charles, MO 63301

    Contact for pricing
    11,751 sqft 2.35 AC lot

    Office and warehouse configuration with drive-in access and a fenced, paved storage area.

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    Historic Mixed-Use Building
    Historic Mixed-Use Building

    Saint Charles, MO 63301

    Contact for pricing
    2,862 sqft 0.09 AC lot

    Two-floor brick property with short-term apartments and a gym-ready first floor.

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    Saint Charles, MO Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Saint Charles, MO with 67 listings featured on our commercial real estate exchange. The current inventory includes 377,885 square feet of properties with an estimated lease value of $112.51.

    Estimated lease rates for Commercial real estate in Saint Charles, MO begin at $9 SF/Yr, with an average of $12.50 SF/Yr and extend to $19 SF/Yr.
    Saint Charles, MO CRE market trends — vacancy, lease rates and price per SF, updated monthly
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