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    Lancaster, SC Office Properties & Spaces for Sale

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    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres

    Two Professional Buildings Near MUSC

    1201 Colonial Cmns Ct, Lancaster, SC 29720

    Two professional office buildings near MUSC in Lancaster, South Carolina.

    • Prime location minutes from MUSC (Medical University of South Carolina).
    • Two professional office buildings on one property.
    • Zoned "PO" Professional Office by the City of Lancaster.
    • Building 1 features a medical office layout with 14 rooms and a wired X‑ray room.
    • New flooring and new roof installed in Building 1.
    Updated: Dec 1, 2025
    View details
    Two Professional Buildings Near MUSC
    $1,100,000
    8,482 SF

    Two Professional Buildings Near MUSC

    1201-1203 Colonial Commons Ct, Lancaster, SC 29720

    Two professional buildings on one property near the Medical University.

    • Two professional buildings on one property, offering flexibility to lease one and occupy the other.
    • Prime location, minutes from MUSC (Medical University of South Carolina).
    • Building 1 is already set up as a medical office with approximately 14 rooms, reception, waiting area, and wired for X‑ray.
    • Existing lease on one building provides immediate income upon purchase.
    • Building 2 offers a versatile layout with curtained areas, reception, waiting area, large open space, and workstations.
    View details
    Lancaster Light Industrial Facility
    $325,000
    3,400 SF

    Lancaster Light Industrial Facility

    3,400 SF facility on 2 acres near Rock Hill.

    1537 Lynwood Dr, Lancaster, SC 29720
    View details
    Based on your search, we've compiled 189 Potential Opportunities for your consideration. Besides 3 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 178 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Commercial Property with Four Buildings
    $680,000
    8,165 SF

    Commercial Property with Four Buildings

    Commercial/industrial property featuring four buildings on 0.92 acres.

    960 Workman St Rock Hl, Rock Hill, SC 29730
    View details
    Mixed-Use Buildings in Rock Hill
    $680,000
    8,165 SF

    Mixed-Use Buildings in Rock Hill

    Four buildings with office and warehouse space in Rock Hill.

    966 E Black St, Rock Hill, SC 29730
    View details
    Office Space Available For Sale
    $400,975
    1,250 SF

    Office Space Available For Sale

    Office property with 1250 square feet of space.

    17232 Lancaster Hwy, Charlotte, NC 28277
    View details
    Commercial Condo in Fox Run
    $1,250,000
    3,750 SF

    Commercial Condo in Fox Run

    Office condo for sale in growing Charlotte business park.

    17228 Lancaster Hwy, Charlotte, NC 28277
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Lancaster Land For Sale
    $115,000
    11.66 Acres

    Lancaster Land For Sale

    11.66 acres of wooded property in downtown Lancaster, SC.

    Woodland Dr, Lancaster, SC 29720
    View details
    Commercial Land in Lancaster, SC
    $75,000
    0.28 Acres

    Commercial Land in Lancaster, SC

    Prime commercial land with high visibility and easy access.

    E Arch St, Lancaster, SC 29720
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    Prime Development Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Development Land on Charlotte Highway

    Development opportunity on a high-traffic corridor near residential developments.

    2383 Charlotte Hwy, Lancaster, SC 29720
    View details
    Prime Commercial Land on Charlotte Highway
    $2,200,000
    15.55 Acres

    Prime Commercial Land on Charlotte Highway

    15.55 acres with high traffic and development potential.

    2383 Charlotte Hwy, Lancaster, SC 29720
    View details

    Explore Off-Market Properties in Lancaster, SC

    Consider similar Off-Market properties in Lancaster, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    945-973 Highway 9 Byp

    945-973 Highway 9 Byp

    Restaurants • 12,800 SF
    Value Estimation by Request
    945-973 Highway 9 Byp, Lancaster, SC 29720
    View details
    209 Main St

    209 Main St

    Restaurants • 96,454 SF
    Value Estimation by Request
    209 Main St, Lancaster, SC 29720
    View details
    1201 Colonial Commons Ct

    1201 Colonial Commons Ct

    Medical offices • 8,482 SF
    Value Estimation by Request
    1201 Colonial Commons Ct, Lancaster, SC 29720
    View details
    905-933 Highway 9 Byp

    905-933 Highway 9 Byp

    Restaurants • 14,400 SF
    Value Estimation by Request
    905-933 Highway 9 Byp, Lancaster, SC 29720
    View details
    1005 Meeting St

    1005 Meeting St

    MEDICAL BUILDING • 8,804 SF
    Value Estimation
    $360,000
    1005 Meeting St, Lancaster, SC 29720-2205
    View details
    134 Rebound Rd

    134 Rebound Rd

    MEDICAL BUILDING • 17,090 SF
    Value Estimation
    $930,000
    134 Rebound Rd, Lancaster, SC 29720-7712
    View details
    111 Covenant Pl

    111 Covenant Pl

    OFFICE (GENERAL) • 10,649 SF
    Value Estimation by Request
    111 Covenant Pl, Lancaster, SC 29720-3165
    View details
    5222 Old Hickory Rd

    5222 Old Hickory Rd

    OFFICE (GENERAL) • 1,327 SF
    Value Estimation
    $170,000
    5222 Old Hickory Rd, Lancaster, SC 29720-0320
    View details
    2145 Pageland Hwy

    2145 Pageland Hwy

    OFFICE (GENERAL) • 5,944 SF
    Value Estimation
    $350,000
    2145 Pageland Hwy, Lancaster, SC 29720-7609
    View details
    602 Main St

    602 Main St

    OFFICE (GENERAL) • 1,744 SF
    Value Estimation
    $160,000
    602 Main St, Lancaster, SC 29720-3624
    View details
    1003 Meeting St

    1003 Meeting St

    MEDICAL BUILDING • 6,041 SF
    Value Estimation
    $365,000
    1003 Meeting St, Lancaster, SC 29720-2205
    View details
    737 Plantation Rd

    737 Plantation Rd

    OFFICE (GENERAL) • 131,000 SF
    Value Estimation by Request
    737 Plantation Rd, Lancaster, SC 29720-5808
    View details
    2048 Great Fls Hwy

    2048 Great Fls Hwy

    OFFICE (GENERAL) • 960 SF
    Value Estimation
    $200,000
    2048 Great Fls Hwy, Lancaster, SC 29720-7171
    View details
    1710 Charlotte Hwy

    1710 Charlotte Hwy

    OFFICE (GENERAL) • 14,104 SF
    Value Estimation
    $260,000
    1710 Charlotte Hwy, Lancaster, SC 29720-8799
    View details
    217 Knolwood, Unit DR

    217 Knolwood, Unit DR

    OFFICE (GENERAL) • 2,304 SF
    Value Estimation
    $230,000
    217 Knolwood, Lancaster, SC 29720
    View details
    1190 Hwy 9th W Byp

    1190 Hwy 9th W Byp

    MEDICAL BUILDING • 2,000 SF
    Value Estimation
    $190,000
    1190 Hwy 9th W Byp, Lancaster, SC 29720-1709
    View details
    973 Main St

    973 Main St

    OFFICE (GENERAL) • 1,448 SF
    Value Estimation
    $140,000
    973 Main St, Lancaster, SC 29720-2188
    View details
    2475 Dhec Rd

    2475 Dhec Rd

    OFFICE (GENERAL) • 5,478 SF
    Value Estimation by Request
    2475 Dhec Rd, Lancaster, SC 29720-2901
    View details
    208 Dunlap St

    208 Dunlap St

    MEDICAL BUILDING • 1,517 SF
    Value Estimation
    $115,000
    208 Dunlap St, Lancaster, SC 29720-2511
    View details
    1240 Colonial Cmns Ct

    1240 Colonial Cmns Ct

    MEDICAL BUILDING • 11,391 SF
    Value Estimation
    $465,000
    1240 Colonial Cmns Ct, Lancaster, SC 29720-2200
    View details
    104 Catawba St

    104 Catawba St

    OFFICE (GENERAL) • 2,152 SF
    Value Estimation
    $210,000
    104 Catawba St, Lancaster, SC 29720-2412
    View details

    Lancaster, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 181 office properties & spaces for sale in Lancaster, SC, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 310,950,107 square feet of properties for sale, with an estimated market value of $38,125,000.

    Prices for office spaces in Lancaster, SC start at $55,000, averaging $377,475, and reaching up to $6,550,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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    Most Searched ZIP Codes in Lancaster, SC

    • 29720

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