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    Lancaster, SC Office Properties & Spaces for Sale

    7 results
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    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres

    Two Professional Buildings Near MUSC

    1201 Colonial Cmns Ct, Lancaster, SC 29720

    Two professional office buildings near MUSC in Lancaster, South Carolina.

    • Prime location minutes from MUSC (Medical University of South Carolina).
    • Two professional office buildings on one property.
    • Zoned "PO" Professional Office by the City of Lancaster.
    • Building 1 features a medical office layout with 14 rooms and a wired X‑ray room.
    • New flooring and new roof installed in Building 1.
    Updated: Dec 1, 2025
    View details
    Medical Office Buildings Near MUSC
    $975,000

    Medical Office Buildings Near MUSC

    1201 Colonial Commons Ct, Lancaster, SC 29720

    Two professional buildings suitable for medical or office use.

    • Prime location minutes from MUSC.
    • Two professional office buildings on one property.
    • Building 1 is set up as a medical office with 14 rooms and wired for an X‑ray room.
    • Zoned "PO" Professional Office by the City of Lancaster.
    • New flooring and roof in Building 1.
    Updated: Dec 1, 2025
    View details
    Lancaster Light Industrial Facility
    $325,000
    3,400 SF

    Lancaster Light Industrial Facility

    3,400 SF facility on 2 acres near Rock Hill.

    1537 Lynwood Dr, Lancaster, SC 29720
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    Two Professional Buildings Near MUSC
    $1,100,000
    8,482 SF

    Two Professional Buildings Near MUSC

    Two professional buildings on one property near the Medical University.

    1201-1203 Colonial Commons Ct, Lancaster, SC 29720
    View details
    Mixed-Use Commercial Property For Sale
    $450,000

    Mixed-Use Commercial Property For Sale

    Four buildings with six potential rental opportunities on 1.6 acres.

    2415 Pineview Dr, Lancaster, SC 29720
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    Versatile Commercial Space For Sale
    Contact for pricing

    Versatile Commercial Space For Sale

    Functional office space with recent renovations and convenient location.

    309 N Main St, Lancaster, SC 29720
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    Lancaster Commercial Property for Sale
    $149,900
    1,248 SF

    Lancaster Commercial Property for Sale

    Commercial property suitable for office, retail, or healthcare use.

    2836 Lynwood Dr, Lancaster, SC 29720
    View details
    Based on your search, we've compiled 193 Potential Opportunities for your consideration. Besides 7 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 178 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Commercial Property with Four Buildings
    $680,000
    8,165 SF

    Commercial Property with Four Buildings

    Commercial/industrial property featuring four buildings on 0.92 acres.

    960 Workman St Rock Hl, Rock Hill, SC 29730
    View details
    Rock Hill Warehouse Sublease Opportunity
    Contact for pricing
    54,500 SF

    Rock Hill Warehouse Sublease Opportunity

    Warehouse sublease in Rock Hill's TechPark Business Park.

    467 Lakeshore Pkwy, Rock Hill, SC 29730
    View details
    Office Space Available For Sale
    $400,975
    1,250 SF

    Office Space Available For Sale

    Office property with 1250 square feet of space.

    17232 Lancaster Hwy, Charlotte, NC 28277
    View details
    Commercial Condo in Fox Run
    Contact for pricing
    3,750 SF

    Commercial Condo in Fox Run

    Office condo for sale in growing Charlotte business park.

    17228 Lancaster Hwy, Charlotte, NC 28277
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Lancaster Land For Sale
    $115,000
    11.66 Acres

    Lancaster Land For Sale

    11.66 acres of wooded property in downtown Lancaster, SC.

    Woodland Dr, Lancaster, SC 29720
    View details
    Commercial Land in Lancaster, SC
    $75,000
    0.28 Acres

    Commercial Land in Lancaster, SC

    Prime commercial land with high visibility and easy access.

    E Arch St, Lancaster, SC 29720
    View details
    Commercial Lot on Highway S 200
    $69,000
    0.50 Acres

    Commercial Lot on Highway S 200

    Prime commercial lot with high visibility and utilities connected.

    2067 Great Falls Hwy, Lancaster, SC 29720
    View details
    Commercial Lot on Highway S 200
    $69,900
    0.50 Acres

    Commercial Lot on Highway S 200

    Prime commercial lot with high visibility and utilities access.

    2067 Great Falls Hwy, Lancaster, SC 29720
    View details

    Explore Off-Market Properties in Lancaster, SC

    Consider similar Off-Market properties in Lancaster, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    905-933 Highway 9 Byp

    905-933 Highway 9 Byp

    Restaurants • 14,400 SF
    Value Estimation by Request
    905-933 Highway 9 Byp, Lancaster, SC 29720
    View details
    Catawba St

    Catawba St

    OFFICE (GENERAL) • 2,268 SF
    Value Estimation by Request
    Catawba St, Lancaster, SC 29720
    View details
    Colonial Ave

    Colonial Ave

    OFFICE (GENERAL) • 5,148 SF
    Value Estimation by Request
    Colonial Ave, Lancaster, SC 29720
    View details
    122 Market St

    122 Market St

    OFFICE (GENERAL) • 266 SF
    Value Estimation by Request
    122 Market St, Lancaster, SC 29720-2552
    View details
    1003 Meeting St

    1003 Meeting St

    MEDICAL BUILDING • 6,041 SF
    Value Estimation by Request
    1003 Meeting St, Lancaster, SC 29720-2205
    View details
    1001 Meeting St

    1001 Meeting St

    OFFICE (GENERAL) • 11,390 SF
    Value Estimation
    $635,000
    1001 Meeting St, Lancaster, SC 29720-2205
    View details
    201 Meeting St Ste A

    201 Meeting St Ste A

    MEDICAL BUILDING • 11,301 SF
    Value Estimation
    $505,000
    201 Meeting St Ste A, Lancaster, SC 29720-2380
    View details
    Riverside Rd

    Riverside Rd

    OFFICE (GENERAL) • 6,285 SF
    Value Estimation
    $530,000
    Riverside Rd, Lancaster, SC 29720
    View details
    1201 Colonial Commons Ct

    1201 Colonial Commons Ct

    Medical Office Space • 8,482 SF
    Value Estimation by Request
    1201 Colonial Commons Ct, Lancaster, SC 29720
    View details
    720 Main St

    720 Main St

    MEDICAL BUILDING • 2,250 SF
    Value Estimation by Request
    720 Main St, Lancaster, SC 29720-3653
    View details
    737 Plantation Rd

    737 Plantation Rd

    OFFICE (GENERAL) • 131,000 SF
    Value Estimation
    $11,005,000
    737 Plantation Rd, Lancaster, SC 29720-5808
    View details
    705 White St

    705 White St

    OFFICE (GENERAL) • 3,860 SF
    Value Estimation by Request
    705 White St, Lancaster, SC 29720-2174
    View details
    2475 Dhec Rd

    2475 Dhec Rd

    OFFICE (GENERAL) • 5,478 SF
    Value Estimation by Request
    2475 Dhec Rd, Lancaster, SC 29720-2901
    View details
    208 Main St

    208 Main St

    OFFICE (GENERAL) • 1,560 SF
    Value Estimation by Request
    208 Main St, Lancaster, SC 29720-2444
    View details
    1370 Meeting St

    1370 Meeting St

    MEDICAL BUILDING • 7,654 SF
    Value Estimation
    $725,000
    1370 Meeting St, Lancaster, SC 29720-2222
    View details
    1000 Miller Rdg Ln

    1000 Miller Rdg Ln

    OFFICE (GENERAL) • 1,551 SF
    Value Estimation
    $6,960,000
    1000 Miller Rdg Ln, Lancaster, SC 29720-8571
    View details
    1601 Pageland Hwy

    1601 Pageland Hwy

    OFFICE (GENERAL) • 4,747 SF
    Value Estimation
    $505,000
    1601 Pageland Hwy, Lancaster, SC 29720-8535
    View details

    Lancaster, SC Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 185 office properties & spaces for sale in Lancaster, SC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 310,950,107 square feet of properties for sale, with an estimated market value of $38,125,000.

    Sale prices for office spaces in Lancaster, SC start at $55,000, averaging $377,475, and reaching up to $6,550,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Office properties & Spaces for Sale Near Lancaster, SC

    Popular Searches in Lancaster, SC

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    Most Searched ZIP Codes in Lancaster, SC

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