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    Natchez, MS Office Properties & Spaces for Sale

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    Gulfport, MS Jackson, MS Hattiesburg, MS
    9 results
    Natchez Medical Facility For Sale
    $275,000
    4,583 SF

    Natchez Medical Facility For Sale

    500 N Martin Luther King Street, Natchez, MS 39120

    Over 4,500 SF commercial building in Natchez, Mississippi.

    • Over 4,500 square feet of building space.
    • Zoned B‑1 neighborhood business district.
    • Ideal setup for shared practices with multiple patient rooms, offices, and restrooms on each side.
    • Large reception and waiting room area.
    • Located in the heart of Natchez.
    Updated: Dec 4, 2025
    View details
    Versatile Commercial Space in Natchez
    Contact for pricing
    1,600 SF

    Versatile Commercial Space in Natchez

    151 Jefferson Davis Boulevard, Natchez, MS 39120

    Adaptable 1,600 sq ft space suitable for various businesses.

    • Prime commercial location in a desirable area of Natchez, MS.
    • Customizable 1,600 sq ft space adaptable for retail, office, or professional services.
    • Owner willing to build out the interior to tenant specifications.
    • High traffic exposure and strong surrounding businesses.
    • Convenient access to local amenities.
    Updated: May 16, 2025
    View details
    Downtown Natchez Mixed-Use Opportunity
    $875,000
    4,400 SF

    Downtown Natchez Mixed-Use Opportunity

    Two-story historical building in downtown Natchez with commercial and residential potential.

    433 Main Street, Natchez, MS 39120
    View details
    Versatile Commercial Property with Warehouse
    $205,000
    2,450 SF

    Versatile Commercial Property with Warehouse

    Commercial property featuring offices and a large warehouse area.

    235 Highway 61, Natchez, MS 39120
    View details
    Two Natchez Office Buildings
    $525,000
    3,500 SF

    Two Natchez Office Buildings

    Two office buildings on 0.51 acres in Natchez, MS.

    255 Highway 61, Natchez, MS 39120
    View details
    Natchez Commercial Property For Sale
    $205,000
    2,450 SF

    Natchez Commercial Property For Sale

    Commercial property featuring offices and a large warehouse area.

    235 Highway 61, Natchez, MS 39120
    View details
    Commercial Property on Sgt Prentiss
    $850,000
    30,000 SF

    Commercial Property on Sgt Prentiss

    Commercial property with frontage on Sgt Prentiss Drive and Liberty Road.

    260 Sgt Prentiss Dr, Natchez, MS 39120
    View details
    Mixed-Use Property with Multiple Buildings
    $995,000
    19,434 SF

    Mixed-Use Property with Multiple Buildings

    4.8-acre property featuring six freestanding buildings, some currently rented.

    255 US-61, Natchez, MS 39120
    View details
    Commercial Land on Corporate Blvd
    $199,250

    Commercial Land on Corporate Blvd

    Land suitable for retail or office with highway visibility.

    526 Highway 61 North, Natchez, MS 39120
    View details
    Based on your search, we've compiled 289 Potential Opportunities for your consideration. Besides 9 Active listings in Natchez, MS, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 272 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Prime Commercial Location, Vidalia, LA
    $400,000
    0.72 Acres

    Prime Commercial Location, Vidalia, LA

    High-visibility commercial location ideal for retail, office, restaurant, or investment.

    1634 Carter Street, Vidalia, LA 71373
    View details
    Ferriday Office Building For Sale
    $225,000
    2,360 SF

    Ferriday Office Building For Sale

    Long-standing office building suitable for medical or professional use.

    200 Serio Boulevard, Ferriday, LA 71334
    View details
    Ferriday Office Building For Sale
    $195,000
    4,000 SF

    Ferriday Office Building For Sale

    Long-term leased office building, ideal investment opportunity.

    502 Mickey Gilley Avenue, Ferriday, LA 71334
    View details
    Versatile Multiuse Building For Sale
    $295,000
    8,058 SF

    Versatile Multiuse Building For Sale

    Multiuse building leased to professionals with ample parking.

    309 Texas St, Vidalia, LA 71373
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Pad-Ready Commercial Land Available
    $496,250
    3.54 Acres

    Pad-Ready Commercial Land Available

    Level lot with utilities in a designated opportunity zone.

    000B3 Highway 61 S, Natchez, MS 39120
    View details
    Pad Ready Land For Sale
    $496,250
    3.54 Acres

    Pad Ready Land For Sale

    Pad-ready land with utilities in a designated opportunity zone.

    Highway 61 lot: B3, Natchez, MS 39120
    View details
    Commercial Land on Highway 61
    $248,250
    4.08 Acres

    Commercial Land on Highway 61

    4.08 acre commercial lot in Natchez, Mississippi.

    Highway 61 S lot: B5, Natchez, MS 39120
    View details
    Pad Ready Land For Sale
    $496,250
    3.59 Acres

    Pad Ready Land For Sale

    Leveled 3.59 acre lot with city utilities available.

    S Highway 61 lot: B2, Natchez, MS 39120
    View details

    Explore Off-Market Properties in Natchez, MS

    Consider similar Off-Market properties in Natchez, MS. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    642 Hwy 61st N

    642 Hwy 61st N

    OFFICE (GENERAL) • 2,460 SF
    Value Estimation by Request
    642 Hwy 61st N, Natchez, MS 39120-9102
    View details
    Hwy 61st S

    Hwy 61st S

    OFFICE (GENERAL) • 2,762 SF
    Value Estimation by Request
    Hwy 61st S, Natchez, MS 39120
    View details
    101 Clifton Ave

    101 Clifton Ave

    OFFICE (GENERAL) • 5,061 SF
    Value Estimation by Request
    101 Clifton Ave, Natchez, MS 39120-2305
    View details
    129 Commerce St

    129 Commerce St

    OFFICE (GENERAL) • 1,505 SF
    Value Estimation by Request
    129 Commerce St, Natchez, MS 39120-3307
    View details
    279 Lowr Woodville Rd

    279 Lowr Woodville Rd

    OFFICE (GENERAL) • 4,937 SF
    Value Estimation by Request
    279 Lowr Woodville Rd, Natchez, MS 39120-4467
    View details
    707 Main St

    707 Main St

    OFFICE (GENERAL) • 2,288 SF
    Value Estimation by Request
    707 Main St, Natchez, MS 39120-3327
    View details
    104 Wall St

    104 Wall St

    OFFICE (GENERAL) • 6,441 SF
    Value Estimation by Request
    104 Wall St, Natchez, MS 39120-3477
    View details
    422 Main St

    422 Main St

    OFFICE (GENERAL) • 4,056 SF
    Value Estimation by Request
    422 Main St, Natchez, MS 39120-3464
    View details
    614 Franklin St

    614 Franklin St

    OFFICE (GENERAL) • 3,720 SF
    Value Estimation by Request
    614 Franklin St, Natchez, MS 39120-3312
    View details
    710 Pearl St

    710 Pearl St

    OFFICE (GENERAL) • 1,268 SF
    Value Estimation by Request
    710 Pearl St, Natchez, MS 39120-2359
    View details
    Hwy 61st S

    Hwy 61st S

    OFFICE (GENERAL) • 3,200 SF
    Value Estimation by Request
    Hwy 61st S, Natchez, MS 39120
    View details
    175 Sgt Prentiss Dr

    175 Sgt Prentiss Dr

    OFFICE (GENERAL) • 836 SF
    Value Estimation by Request
    175 Sgt Prentiss Dr, Natchez, MS 39120-4733
    View details
    207 Commerce St

    207 Commerce St

    OFFICE (GENERAL) • 2,152 SF
    Value Estimation by Request
    207 Commerce St, Natchez, MS 39120-3501
    View details
    400 Greenfield Rd

    400 Greenfield Rd

    OFFICE (GENERAL) • 1,168 SF
    Value Estimation by Request
    400 Greenfield Rd, Natchez, MS 39120-8742
    View details
    116 Jefferson Davis Blvd

    116 Jefferson Davis Blvd

    OFFICE (GENERAL) • 3,546 SF
    Value Estimation by Request
    116 Jefferson Davis Blvd, Natchez, MS 39120-5104
    View details

    Natchez, MS Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 281 office properties & spaces for sale in Natchez, MS, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 131,322,563 square feet of properties for sale, with an estimated market value of $31,655,000.

    Sale prices for office spaces in Natchez, MS start at $195,000, averaging $285,180, and reaching up to $875,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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