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Natchez, MS Office Spaces for Lease

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Vidalia, LA North Tunica, MS Ferriday, LA
Flex Space with Warehouse Area
Updated: Aug 19
Flex Space with Warehouse Area

152 Homochitto Street, Natchez, MS 39120

$5,000/Mo
8,846 sqft 0.43 AC lot
3,395 +/- SF of heated and cooled office space
5,451 square feet of shop and warehouse area
0.43‑acre property with concrete outdoor parking
Commercial location at 152 Homochitto Street, Natchez, MS 39120
Public water and public sewer service
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Medical Office Space with Divisible Layout
Updated: Jul 25
Medical Office Space with Divisible Layout

131 Jefferson Davis Boulevard, Natchez, MS 39120

$3,200/Mo
2,900 sqft
Divisible medical office space suitable for smaller unit configurations
2,900 stated property size
Located at 131 Jefferson Davis Boulevard in Natchez, MS 39120
Situated in a high‑traffic area
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Retail Space with Display Windows
Retail Space with Display Windows

290 Sergeant Prentiss Dr, Natchez, MS 39120

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Flexible commercial space with updated finishes, two breakrooms or offices, and two bathrooms.

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Medical Office Space Near Hospital
Medical Office Space Near Hospital

46 Sgt Prentiss Dr, Natchez, MS 39120

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Class A medical building adjacent to Merit Health Natchez hospital.

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Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 4 Active listings in Natchez, MS, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 21 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Two-Story Medical Office Space
Two-Story Medical Office Space

100 Lincoln Avenue, Ferriday, LA 71334

$1,800/Mo
2,272 sqft 0.28 AC lot

Former family medical practice with exam rooms, offices, employee lounge, and customer parking.

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Medical Plaza Office Space Available
Medical Plaza Office Space Available

107 Front Street, Vidalia, LA 71373

$23 SF/Yr
12,000 sqft

Up to 12,000 SF available in medical plaza.

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Two-Story Medical Office Space
Two-Story Medical Office Space

100 Lincoln Ave, Ferriday, LA 71334

$1,800/Mo
2,272 sqft

Configured for clinical operations with exam rooms, administrative offices, employee facilities, and customer parking.

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Office Space for Lease
Office Space for Lease

11 Cedar Street, Vidalia, LA 71373

$725/Mo

Flexible office units available for lease in Concordia Parish, suited for professional and administrative tenants.

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Similar Spaces for Sale in Natchez, MS

Consider Similar Space for Sale. We found 21 Spaces matching your search parameters.

Multi-Building Office Property
Multi-Building Office Property

131 Jefferson Davis Boulevard, Natchez, MS 39120

$1,990,000
24,060 sqft 3.44 AC lot

Flexible office layouts support varied suite configurations and tenant requirements.

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Flexible Multi-Office Buildings
Flexible Multi-Office Buildings

131 Jefferson Davis Blvd, Natchez, MS 39120

$1,990,000
24,060 sqft 3.44 AC lot

Two buildings provide adaptable office layouts and established occupancy across a commercial tract.

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Historic Two-Story Mixed-Use Building
Historic Two-Story Mixed-Use Building

126 S Commerce Street, Natchez, MS 39120

$495,000
9,500 sqft

Brick commercial property with office suites, retail areas, an elevator, and existing occupants in downtown Natchez.

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Historic Two-Story Mixed-Use Building
Historic Two-Story Mixed-Use Building

126 S Commerce St, Natchez, MS 39120

$495,000
9,500 sqft

Downtown property combines office and retail suites with an elevator, basement storage, and existing individual occupants.

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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

326-328 Main Street, Natchez, MS 39120

$675,000
5,304 sqft 0.06 AC lot

Downtown building with a full basement, active office and boutique uses, and an upper-level apartment under construction.

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Historic Mixed-Use Building
Historic Mixed-Use Building

326328 326-328 Main St, Natchez, MS 39120

$675,000
5,304 sqft

Two-story commercial property with a full basement, period details, and an apartment under construction upstairs.

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Flex Space with Rear Warehouse
Flex Space with Rear Warehouse

235 Highway 61, Natchez, MS 39120

$195,000
2,450 sqft

Four offices complement dedicated rear warehouse space in a practical commercial configuration.

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Spa and Wellness Commercial Building
Spa and Wellness Commercial Building

151 E Franklin St, Natchez, MS 39120

$225,000
2,436 sqft

Commercial property with prior beauty and spa use and flexibility for office or retail occupancy.

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Brick Office Building with Covered Drive-Through
Brick Office Building with Covered Drive-Through

329 Lower Woodville Rd, Natchez, MS 39120

$210,000
3,204 sqft

Interior includes reception space, two large rooms, storage, an office, and a half bath.

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Medical Office Building
Medical Office Building

500 N Martin Luther King Street, Natchez, MS 39120

$275,000
4,583 sqft 0.70 AC lot

B-1 neighborhood business zoning supports a multi-room layout with reception, offices, restrooms, and patient areas.

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Historic Two-Story Office Building
Historic Two-Story Office Building

412 Main St, Natchez, MS 39120

$389,000
3,420 sqft

Two-story office building with a renovated main level and an upper level that needs rehabbing.

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Brick Office Building with Covered Drive-Through
Brick Office Building with Covered Drive-Through

329 Lower Woodville Road, Natchez, MS 39120

$195,000
3,204 sqft 0.44 AC lot

Single-story commercial building with reception space, private offices, storage, and a covered side drive-through.

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Two-Building Office Property
Two-Building Office Property

255 Highway 61, Natchez, MS 39120

$525,000
3,500 sqft

Two brick office buildings on a compact commercial lot, including one leased building with an existing two-year term.

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Updated Medical Office Space
Updated Medical Office Space

B-142 Jefferson Davis Blvd, Natchez, MS 39120

$220,000
1,800 sqft

Refreshed interiors provide flexible rooms for examinations, administration, and day-to-day office operations.

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Renovated Mixed-Use Corner Building
Renovated Mixed-Use Corner Building

701 Franklin St, Natchez, MS 39120

$329,500
3,069 sqft

Single-story property combines an adaptable commercial area with a private one-bedroom residence and separate entrance.

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Office Building with Full Kitchen
Office Building with Full Kitchen

154 Providence Road, Natchez, MS 39120

$415,000

Includes conference space, separate restrooms, a private sauna, and off-street parking.

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Three-Story Mixed-Use Building
Three-Story Mixed-Use Building

520 Main St, Natchez, MS 39120

Contact for pricing
11,000 sqft

The property combines a large showroom with office, storage, and basement areas in a three-level commercial layout.

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Multi-Use Downtown Commercial Building
Multi-Use Downtown Commercial Building

414 Main St, Natchez, MS 39120

Contact for pricing

Multi-level building with main-floor retail and upper-level office units on Main Street in downtown Natchez.

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Two-Building Office Property
Two-Building Office Property

255 Highway 61, Natchez, MS 39120

$525,000
3,500 sqft 0.51 AC lot

Brick office improvements on a 0.51-acre site include a leased single-story building and a separate two-story structure.

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Four-Office Flex Building
Four-Office Flex Building

235 Highway 61, Natchez, MS 39120

$195,000
2,450 sqft 0.88 AC lot

The property combines office rooms with a substantial rear warehouse area.

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Natchez, MS Office Spaces Lease Rates & Market Statistics

Browse 4 Office Spaces for lease in Natchez, MS on Realmo, a commercial real estate marketplace serving the Natchez area. The current inventory totals 11,746 square feet of properties.

Asking lease rates for Office Spaces in Natchez start at $6.78 SF/Yr, average $10.01 SF/Yr, and reach $13.24 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $10.01 SF/Yr, the local average runs 45% below Mississippi's state average of $18.11 SF/Yr.

Natchez accounts for 100% of the 4 office spaces currently available across Adams County. By space type, the market includes 3 medical office space listings and 3 office units — office units typically offer the lowest entry point, while medical office space commands the highest rates.

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