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    Natchez, MS Office Properties & Spaces for Lease

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    Jackson, MS Ridgeland, MS Hattiesburg, MS
    6 results
    Downtown Natchez Office Space
    $800 /Mo
    1,000 SF

    Downtown Natchez Office Space

    104 S Wall Street, Natchez, MS 39120

    Recently renovated office space for lease in downtown Natchez.

    • Prime downtown Natchez location across from the courthouse
    • Recently renovated office space
    • Utilities included in monthly rent
    • Includes reception area, 2 offices, and a break room
    • Approximately 1000‑1200 square feet of space
    Updated: Oct 20, 2025
    View details
    Natchez Office Space For Rent
    $1,500 /Mo
    1,100 SF

    Natchez Office Space For Rent

    151 Jefferson Davis Blvd lot: B, Natchez, MS 39120

    Commercial office space suitable for medical, wellness, or professional use.

    • Prime location in a highly sought‑after area of Natchez, MS.
    • Move‑in ready condition, ideal for immediate occupancy.
    • Well‑designed layout featuring five private exam/office rooms.
    • Suitable for medical, wellness, or professional services.
    • Includes a large waiting area and dedicated reception space.
    Updated: May 16, 2025
    View details
    Natchez Office Space For Rent
    $1,250 /Mo
    950 SF

    Natchez Office Space For Rent

    950 sq ft office space in Natchez, Mississippi.

    151 Jefferson Davis Boulevard lot: E, Natchez, MS 39120
    View details
    Downtown Natchez Renovated Office Space
    $1,200 /Mo
    1,200 SF

    Downtown Natchez Renovated Office Space

    Recently renovated office space for lease in downtown Natchez.

    104 S Wall St, Natchez, MS 39120
    View details
    Medical Office Shell Space
    $20 SF/Yr
    3,080 SF

    Medical Office Shell Space

    3,080 SF shell space in Class A medical office.

    46 Sgt Prentiss Pkwy, Natchez, MS
    View details
    Medical Office Space Near Hospital
    Contact for pricing

    Medical Office Space Near Hospital

    Class A medical building adjacent to Merit Health Natchez hospital.

    46 Sgt Prentiss Dr, Natchez, MS 39120
    View details
    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 6 Active listings in Natchez, MS, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

    Explore Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Brookhaven Commercial Space for Rent
    $2,000 /Mo
    2,000 SF

    Brookhaven Commercial Space for Rent

    2,000 SF office suite in Brookhaven's central business district.

    128 S First Street, Brookhaven, MS 39601
    View details
    Downtown Brookhaven Office Space
    $1,500 /Mo
    1,500 SF

    Downtown Brookhaven Office Space

    1500 sq ft office in Brookhaven's central business district.

    127 E Cherokee Street, Brookhaven, MS 39601
    View details
    New Commercial Building in Newellton
    $439,000

    New Commercial Building in Newellton

    New commercial building suitable for retail, office, or medical use.

    1106 Verona Street, Newellton, LA 71357
    View details
    Newellton Freestanding Building For Lease
    $7,622 /Mo
    10,163 SF

    Newellton Freestanding Building For Lease

    New freestanding building suitable for retail, office, or medical uses.

    1106 Verona St, Newellton, LA
    View details

    Explore Similar Spaces for Sale in Natchez, MS

    Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

    Natchez Medical Facility For Sale
    $275,000
    4,583 SF

    Natchez Medical Facility For Sale

    Over 4,500 SF commercial building in Natchez, Mississippi.

    500 N Martin Luther King Street, Natchez, MS 39120
    View details
    Versatile Commercial Space in Natchez
    Contact for pricing
    1,600 SF

    Versatile Commercial Space in Natchez

    Adaptable 1,600 sq ft space suitable for various businesses.

    151 Jefferson Davis Boulevard, Natchez, MS 39120
    View details
    Downtown Natchez Mixed-Use Opportunity
    $875,000
    4,400 SF

    Downtown Natchez Mixed-Use Opportunity

    Two-story historical building in downtown Natchez with commercial and residential potential.

    433 Main Street, Natchez, MS 39120
    View details
    Versatile Commercial Property with Warehouse
    $205,000
    2,450 SF

    Versatile Commercial Property with Warehouse

    Commercial property featuring offices and a large warehouse area.

    235 Highway 61, Natchez, MS 39120
    View details
    Two Natchez Office Buildings
    $525,000
    3,500 SF

    Two Natchez Office Buildings

    Two office buildings on 0.51 acres in Natchez, MS.

    255 Highway 61, Natchez, MS 39120
    View details
    Natchez Commercial Property For Sale
    $205,000
    2,450 SF

    Natchez Commercial Property For Sale

    Commercial property featuring offices and a large warehouse area.

    235 Highway 61, Natchez, MS 39120
    View details
    Commercial Property on Sgt Prentiss
    $850,000
    30,000 SF

    Commercial Property on Sgt Prentiss

    Commercial property with frontage on Sgt Prentiss Drive and Liberty Road.

    260 Sgt Prentiss Dr, Natchez, MS 39120
    View details
    Mixed-Use Property with Multiple Buildings
    $995,000
    19,434 SF

    Mixed-Use Property with Multiple Buildings

    4.8-acre property featuring six freestanding buildings, some currently rented.

    255 US-61, Natchez, MS 39120
    View details
    Commercial Land on Corporate Blvd
    $199,250

    Commercial Land on Corporate Blvd

    Land suitable for retail or office with highway visibility.

    526 Highway 61 North, Natchez, MS 39120
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Land For Lease
    $4,500 /Mo

    Prime Commercial Land For Lease

    High-exposure land lease opportunity on West Pinhook Road.

    1926 W Pinhook Road lot: 6, Lafayette, LA 70508
    View details
    Cleared Land Ready for Development
    $2,000 /Mo

    Cleared Land Ready for Development

    0.27 acre commercial land for lease in Lake Charles.

    806 17th, Lake Charles, LA 70601
    View details
    Tyler, TX Land For Lease
    $20,000 /Mo
    20,000 SF

    Tyler, TX Land For Lease

    Land for lease in Tyler, TX with build to suit opportunity.

    5637 Paluxy Dr, Tyler, TX 75703
    View details
    Tyler, TX Retail/Office Space
    $3,480 /Mo

    Tyler, TX Retail/Office Space

    Retail or office build-to-suit for lease in Tyler, TX.

    5647 KPE Way, Tyler, TX 75703
    View details

    Natchez, MS Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Natchez, MS with 6 listings featured on our commercial real estate exchange. The current inventory includes 132,858,000 square feet of properties with an estimated lease value of $41 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Natchez, MS begin at $9 SF/Yr, with an average of $13 SF/Yr and extend to $16 SF/Yr.
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    Most Searched ZIP Codes in Natchez, MS

    • 39120

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