Natchez, MS
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    Natchez, MS Medical Office Space for Sale

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    Vidalia, LA Ferriday, LA Roxie, MS
    Natchez Medical Facility For Sale
    $275,000
    4,583 SF
    Natchez Medical Facility For Sale

    500 N Martin Luther King Street, Natchez, MS 39120

    Over 4,500 SF commercial building in Natchez, Mississippi.
    • Over 4,500 square feet of building space.
    • Zoned B‑1 neighborhood business district.
    • Ideal setup for shared practices with multiple patient rooms, offices, and restrooms on each side.
    • Large reception and waiting room area.
    • Located in the heart of Natchez.
    Updated: Dec 4, 2025
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    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 1 Active listings in Natchez, MS, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 14 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Ferriday Commercial Office Building For Sale
    $195,000
    2,360 SF
    Ferriday Commercial Office Building For Sale

    Long-standing office building suitable for medical or professional use.

    200 Serio Boulevard, Ferriday, LA 71334

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    Rayville Medical Office Investment
    $550,000
    1.69 Acres
    Rayville Medical Office Investment

    Fully occupied medical office building with expansion potential.

    161 Christian Dr, Rayville, LA

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    Downtown Ferriday Commercial Building
    $195,000
    8,000 SF
    Downtown Ferriday Commercial Building

    Unique commercial building in downtown Ferriday with available space.

    104 Louisiana Ave, Ferriday, LA 71334

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    Rayville Medical Office Investment Opportunity
    $550,000
    5,993 SF
    Rayville Medical Office Investment Opportunity

    Medical office building with established tenants and expansion potential.

    161 CHRISTIAN DRIVE, Rayville, LA 71269

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    McComb Land Near Medical Center
    $199,500
    1.49 Acres
    McComb Land Near Medical Center

    1.49 acre commercial/residential land near SW Mississippi Medical Center.

    Llewellyn Ave, Mccomb, MS 39648

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    Baton Rouge Commercial Land Available
    $350,000
    2.66 Acres
    Baton Rouge Commercial Land Available

    2.66 acres in up-and-coming area with diverse development potential.

    Tbd Greenwell Springs Rd, Baton Rouge, LA 70814

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    Commercial Land in Clinton, MS
    $600,000
    4.94 Acres
    Commercial Land in Clinton, MS

    4.94 acres suitable for commercial development in Clinton, MS.

    St. Thomas Parkway, Clinton, MS 39056

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    Land For Sale in Clinton
    $75,000
    0.62 Acres
    Land For Sale in Clinton

    Land for sale off I-20 in Clinton, Mississippi.

    St Thomas Parkway, Clinton, MS 39056

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    Off-Market Properties in Natchez, MS

    Consider similar Off-Market properties in Natchez, MS. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    5 Stahlman St
    MEDICAL BUILDING
    5,468 SF
    Value Estimation by Request

    5 Stahlman St, Natchez, MS 39120-4612

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    19 Sgt Prentiss Dr
    MEDICAL BUILDING
    2,184 SF Lot: 0.39 Acres
    Value Estimation by Request

    19 Sgt Prentiss Dr, Natchez, MS 39120-4727

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    46 Sgt Prentiss Dr
    MEDICAL BUILDING
    44,504 SF Lot: 2.09 Acres

    46 Sgt Prentiss Dr, Natchez, MS 39120-4792

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    149 Pilgrim Rd
    MEDICAL BUILDING
    2,324 SF Lot: 0.44 Acres
    Value Estimation by Request

    149 Pilgrim Rd, Natchez, MS 39120-2650

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    404 Liberty Rd
    MEDICAL BUILDING
    2,573 SF Lot: 0.31 Acres
    Value Estimation by Request

    404 Liberty Rd, Natchez, MS 39120-4314

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    John R Junkin Dr
    MEDICAL BUILDING
    10,848 SF Lot: 1.30 Acres
    Value Estimation by Request

    John R Junkin Dr, Natchez, MS 39120

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    201 John R Junkin Dr
    MEDICAL BUILDING
    5,600 SF
    Value Estimation by Request

    201 John R Junkin Dr, Natchez, MS 39120-3870

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    136 Jefferson Davis Blvd
    MEDICAL BUILDING
    7,617 SF Lot: 1.44 Acres
    Value Estimation by Request

    136 Jefferson Davis Blvd, Natchez, MS 39120-5104

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    142 Jefferson Davis Blvd
    MEDICAL BUILDING
    4,265 SF Lot: 1.07 Acres
    Value Estimation by Request

    142 Jefferson Davis Blvd, Natchez, MS 39120-5104

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    150 Jefferson Davis Blvd
    MEDICAL BUILDING
    15,934 SF Lot: 2.47 Acres
    Value Estimation by Request

    150 Jefferson Davis Blvd, Natchez, MS 39120-5107

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    140 Jefferson Davis Blvd
    MEDICAL BUILDING
    3,829 SF Lot: 1.31 Acres
    Value Estimation by Request

    140 Jefferson Davis Blvd, Natchez, MS 39120-5104

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    101 Hwy 61st S
    MEDICAL BUILDING
    4,816 SF
    Value Estimation by Request

    101 Hwy 61st S, Natchez, MS 39120-5216

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    316 Highland Blvd
    MEDICAL BUILDING
    6,263 SF
    Value Estimation by Request

    316 Highland Blvd, Natchez, MS 39120

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    62 Concord Ave
    MEDICAL BUILDING
    1,232 SF Lot: 0.29 Acres
    Value Estimation by Request

    62 Concord Ave, Natchez, MS 39120

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    Natchez, MS Medical Office Space Investment Opportunities Market Analysis

    Explore 15 medical office space for sale in Natchez, MS on our real estate platform. These investment opportunities span a total of 4,583 square feet of properties for sale, with an estimated market value of $275,000.

    Sale prices for medical spaces in Natchez, MS start at $275,000, averaging $275,000, and reaching up to $275,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 5
    Medical Office Space 3
    Office buildings 3

    Demographics Overview

    Population 29K
    Population Growth (5Y) -6.5%
    Median Household Income $40,586
    College Educated 9.0%

    High-Yield Neighborhoods for Investment

    Identify Natchez submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    39120 $275K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Total CRE Area on Market Trend

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