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    Natchez, MS Mixed-use Properties for Sale

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    Vidalia, LA Ferriday, LA Roxie, MS
    Downtown Natchez Mixed-Use Opportunity
    $875,000
    4,400 SF

    Downtown Natchez Mixed-Use Opportunity

    433 Main Street, Natchez, MS 39120

    Two-story historical building in downtown Natchez with commercial and residential potential.

    • Prime downtown location at the corner of Main Street & Commerce, Natchez, MS.
    • Versatile 2‑story historical building suitable for commercial and residential use.
    • Renovated 2nd level featuring two 2‑bedroom, 2‑bath units with included appliances.
    • Lower level offers great space for retail, office, or other commercial uses.
    • Recipient of a Historic Natchez Foundation Special Merit Award for renovation.
    Updated: Jun 20, 2025
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    Thriving Event Venue & Wedding Barn
    $499,000
    5,000 SF

    Thriving Event Venue & Wedding Barn

    398 Greenfield Rd, Natchez, MS 39120

    Event venue on 3 acres, suitable for various events.

    • Thriving event venue with established business potential.
    • Approximately 3 picturesque acres in a private, wooded setting.
    • Over 5,000 square feet of versatile space under roof.
    • Suitable for weddings, special events, corporate retreats, and more.
    • Open‑concept event space with high ceilings and rustic charm.
    Updated: Feb 20
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    Versatile Building in Natchez, MS
    $185,000
    2,450 SF

    Versatile Building in Natchez, MS

    Well-located 2,450 SF building suitable for various commercial uses.

    245 US-61, Natchez, MS 39120
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    Mixed-Use Property with Multiple Buildings
    $995,000
    19,434 SF

    Mixed-Use Property with Multiple Buildings

    4.8-acre property featuring six freestanding buildings, some currently rented.

    255 US-61, Natchez, MS 39120
    View details
    Based on your search, we've compiled 59 Potential Opportunities for your consideration. Besides 4 Active listings in Natchez, MS, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 47 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Historic Three-Story Building in McComb
    $259,500
    7,121 SF

    Historic Three-Story Building in McComb

    7,121 sq ft historic building in need of restoration.

    114 State Street, Mccomb, MS 39648
    View details
    Brookhaven Commercial Building For Sale
    $139,000
    2,058 SF

    Brookhaven Commercial Building For Sale

    Vintage commercial building with potential for retail, office, or mixed-use.

    444 E Monticello Street, Brookhaven, MS 39601
    View details
    Brookhaven Commercial Building For Sale
    $399,500
    2,762 SF

    Brookhaven Commercial Building For Sale

    Prime commercial building in Brookhaven, MS, suitable for various businesses.

    391 Brookhaven St, Brookhaven, MS 39601
    View details
    Versatile Commercial Building in McComb
    $140,000
    10,532 SF

    Versatile Commercial Building in McComb

    10,532 sq ft commercial building with multiple options.

    210 S Broad Way, Mccomb, MS 39666
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Brookhaven Commercial Land For Sale
    $3,450,000
    4.65 Acres

    Brookhaven Commercial Land For Sale

    Prime commercial land in high-traffic area near major retailers.

    1338b Brookway Boulevard, Brookhaven, MS 39601
    View details
    Prime Development Lot, McComb, MS
    $999,900
    16.87 Acres

    Prime Development Lot, McComb, MS

    16.87-acre commercial lot with high visibility and traffic.

    Pike Point Place, Mccomb, MS 39648
    View details
    Prime Commercial Land For Sale
    $199,000
    0.78 Acres

    Prime Commercial Land For Sale

    0.78-acre commercial land in high-traffic location near major retailers.

    Northwest Avenue, Mccomb, MS 39648
    View details
    Vacant Land Near Delhi, LA
    $619,500
    41.30 Acres

    Vacant Land Near Delhi, LA

    41.3 acres of vacant land suitable for multiple uses.

    0 Hwy 854, Delhi, LA 71232
    View details

    Off-Market Properties in Natchez, MS

    Consider similar Off-Market properties in Natchez, MS. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    402 Main St
    STORE/OFFICE (MIXED USE)
    2,271 SF
    Value Estimation by Request

    402 Main St, Natchez, MS 39120-3464

    View details
    303 Devereaux Dr
    STORE/OFFICE (MIXED USE)
    14,985 SF Lot: 1.74 Acres
    Estimated value
    $1,530,000

    303 Devereaux Dr, Natchez, MS 39120-4207

    View details
    345 Devereaux Dr
    STORE/OFFICE (MIXED USE)
    20,356 SF Lot: 1.13 Acres
    Estimated value
    $1,495,000

    345 Devereaux Dr, Natchez, MS 39120-4207

    View details
    412 Hwy 61st N
    STORE/OFFICE (MIXED USE)
    7,334 SF
    Estimated value
    $755,000

    412 Hwy 61st N, Natchez, MS 39120-4200

    View details
    114 Northgate Rd
    STORE/OFFICE (MIXED USE)
    11,160 SF Lot: 1.66 Acres
    Estimated value
    $680,000

    114 Northgate Rd, Natchez, MS 39120-9161

    View details
    15 Spg St
    STORE/OFFICE (MIXED USE)
    3,150 SF Lot: 0.15 Acres
    Value Estimation by Request

    15 Spg St, Natchez, MS 39120-2838

    View details
    624 Hwy 61st N
    STORE/OFFICE (MIXED USE)
    4,219 SF
    Value Estimation by Request

    624 Hwy 61st N, Natchez, MS 39120-8405

    View details
    131 Winchester Rd
    Multifamily properties
    6,676 SF Lot: 10.60 Acres
    Value Estimation by Request

    131 Winchester Rd, Natchez, MS 39120

    View details
    939 Us-61
    Individual retail properties
    3,000 SF Lot: 4.37 Acres
    Value Estimation by Request

    939 Us-61, Natchez, MS 39120

    View details
    245 Us-61
    Mixed-use properties
    2,450 SF Lot: 0.45 Acres
    Value Estimation by Request

    245 Us-61, Natchez, MS 39120

    View details
    61 251&255 Hwy
    Individual retail properties
    2,000 SF Lot: 0.51 Acres
    Value Estimation by Request

    61 251&255 Hwy, Natchez, MS 39120

    View details
    255 Us-61
    Individual retail properties
    19,434 SF Lot: 4.80 Acres
    Value Estimation by Request

    255 Us-61, Natchez, MS 39120

    View details
    235 Highway 61
    Distribution properties
    2,450 SF Lot: 0.88 Acres
    Value Estimation by Request

    235 Highway 61, Natchez, MS 39120

    View details
    Shields Ln
    STORE/OFFICE (MIXED USE)
    4,400 SF Lot: 1.05 Acres
    Estimated value
    $555,000

    Shields Ln, Natchez, MS 39120

    View details
    270 Sgt Prentiss Dr
    STORE/OFFICE (MIXED USE)
    979 SF Lot: 0.52 Acres
    Value Estimation by Request

    270 Sgt Prentiss Dr, Natchez, MS 39120

    View details
    49 Sgt Prentiss Dr
    STORE/OFFICE (MIXED USE)
    15,027 SF Lot: 1.77 Acres
    Estimated value
    $1,545,000

    49 Sgt Prentiss Dr, Natchez, MS 39120-4727

    View details
    515 Rankin St
    STORE/OFFICE (MIXED USE)
    4,436 SF Lot: 0.16 Acres
    Value Estimation by Request

    515 Rankin St, Natchez, MS 39120-2940

    View details
    122 Pilgrim Rd
    STORE/OFFICE (MIXED USE)
    9,230 SF Lot: 1.47 Acres
    Estimated value
    $740,000

    122 Pilgrim Rd, Natchez, MS 39120-2651

    View details
    613 Main St
    STORE/OFFICE (MIXED USE)
    19,370 SF Lot: 0.89 Acres
    Estimated value
    $705,000

    613 Main St, Natchez, MS 39120-3325

    View details
    108 Liberty Rd
    STORE/OFFICE (MIXED USE)
    2,277 SF
    Value Estimation by Request

    108 Liberty Rd, Natchez, MS 39120-3702

    View details

    Natchez, MS Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 51 mixed-use properties for sale in Natchez, MS, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 31,284 square feet of properties for sale, with an estimated market value of $2,554,000.

    Sale prices for multi use buildings in Natchez, MS start at $185,000, averaging $638,500, and reaching up to $995,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 29K
    Population Growth (5Y) -6.5%
    Median Household Income $40,586
    College Educated 9.0%

    High-Yield Neighborhoods for Investment

    Identify Natchez submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    39120 $638.5K

    Taxes & Financing

    Average Loan-to-Value 65.0%

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