Mixed-Use

Natchez, MS Mixed-use Properties for Sale

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Vidalia, LA Ferriday, LA Roxie, MS Clayton, LA Waterproof, LA Jonesville, LA Lorman, MS Crosby, MS
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Historic Two-Story Mixed-Use Building
Updated: May 16
Historic Two-Story Mixed-Use Building

126 S Commerce Street, Natchez, MS 39120

$495,000
9,500 sqft
Two‑story brick mixed‑use building with approximately 9,500 +/- square feet of finished space
Approximately 1,750 square feet of basement area
First floor includes approximately 7 offices, a break room, and a restroom
Second floor includes 8 +/- offices, storage rooms, and 3 restrooms
Hydraulic elevator and interior stair access between floors
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Two-Story Mixed-Use Building
Updated: Dec 12, 2025
Two-Story Mixed-Use Building

326-328 Main Street, Natchez, MS 39120

$675,000
5,304 sqft 0.06 AC lot
5,304‑square‑foot mixed‑use building on 0.06 acres
Two‑story structure with full basement
Current real estate office and boutique uses
Upper floor under construction for a 2 bedroom 2 bath apartment
Original bank vault, exposed brick, open ceiling beams, and hardwood floors
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Historic Two-Story Mixed-Use Building
Historic Two-Story Mixed-Use Building

126 S Commerce St, Natchez, MS 39120

$495,000
9,500 sqft

Downtown property combines office and retail suites with an elevator, basement storage, and existing individual occupants.

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Historic Mixed-Use Building
Historic Mixed-Use Building

326328 326-328 Main St, Natchez, MS 39120

$675,000
5,304 sqft

Two-story commercial property with a full basement, period details, and an apartment under construction upstairs.

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Williams Isles House Mixed-Use Property
Williams Isles House Mixed-Use Property

657 S Canal St, Natchez, MS 39120

$275,000
2,658 sqft

The property combines commercial and residential zoning with a commercial kitchen, high ceilings, and wood floors.

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Riverfront Mixed-Use Property
Riverfront Mixed-Use Property

100 State Street, Natchez, MS 39120

$500,000

Use concepts include boutique retail, dining, gallery, professional office, and mixed-use redevelopment.

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Renovated Mixed-Use Corner Building
Renovated Mixed-Use Corner Building

701 Franklin St, Natchez, MS 39120

$329,500
3,069 sqft

Single-story property combines an adaptable commercial area with a private one-bedroom residence and separate entrance.

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Historic Multi-Level Restaurant Property
Historic Multi-Level Restaurant Property

619 Jefferson Street, Natchez, MS 39120

$499,000
5,396 sqft

Antebellum brick-and-wood building includes former restaurant space and two first-floor restrooms.

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Based on your search, we've compiled 59 Potential Opportunities for your consideration. Besides 8 Active listings in Natchez, MS, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 47 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Three-Story Historic Office Building
Three-Story Historic Office Building

114 State Street, Mccomb, MS 39648

$259,500
7,121 sqft 0.36 AC lot

A three-level office property with original architectural details and room for comprehensive restoration.

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Mixed-Use Commercial Building
Mixed-Use Commercial Building

391 Brookhaven St, Brookhaven, MS 39601

$399,500
2,762 sqft

Flexible space supports retail, office, or combined commercial use with on-site parking.

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Mixed-Use Property with Banking Suite
Mixed-Use Property with Banking Suite

1405 Aston Avenue, Mccomb, MS 39648

Contact for pricing
6,000 sqft 0.61 AC lot

Multi-tenant commercial property includes storefront, church, and banking-oriented improvements.

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Mixed-Use Commercial Building
Mixed-Use Commercial Building

391 Brookhaven Street, Brookhaven, MS 39601

$399,500
2,762 sqft 2.29 AC lot

Flexible interior supports retail, office, or mixed-use occupancy with room for renovation.

View details

Off-Market Properties in Natchez, MS

Consider similar Off-Market properties in Natchez, MS. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

402 Main St
STORE/OFFICE (MIXED USE)

402 Main St, Natchez, MS 39120-3464

$245,000
Estimated value
2,271 sqft
View details
303 Devereaux Dr
STORE/OFFICE (MIXED USE)

303 Devereaux Dr, Natchez, MS 39120-4207

$1,530,000
Estimated value
14,985 sqft 1.74 AC lot
View details
345 Devereaux Dr
STORE/OFFICE (MIXED USE)

345 Devereaux Dr, Natchez, MS 39120-4207

$1,495,000
Estimated value
20,356 sqft 1.13 AC lot
View details
412 Hwy 61st N
STORE/OFFICE (MIXED USE)

412 Hwy 61st N, Natchez, MS 39120-4200

$755,000
Estimated value
7,334 sqft
View details
114 Northgate Rd
STORE/OFFICE (MIXED USE)

114 Northgate Rd, Natchez, MS 39120-9161

$680,000
Estimated value
11,160 sqft 1.66 AC lot
View details
15 Spg St
STORE/OFFICE (MIXED USE)

15 Spg St, Natchez, MS 39120-2838

$195,000
Estimated value
3,150 sqft 0.15 AC lot
View details
624 Hwy 61st N
STORE/OFFICE (MIXED USE)

624 Hwy 61st N, Natchez, MS 39120-8405

$230,000
Estimated value
4,219 sqft
View details
131 Winchester Rd
Multifamily properties

131 Winchester Rd, Natchez, MS 39120

Value Estimation by Request
6,676 sqft 10.60 AC lot
View details
939 Us-61
Individual retail properties

939 Us-61, Natchez, MS 39120

Value Estimation by Request
3,000 sqft 4.37 AC lot
View details
245 Us-61
Mixed-use properties

245 Us-61, Natchez, MS 39120

Value Estimation by Request
2,450 sqft 0.45 AC lot
View details
61 251&255 Hwy
Individual retail properties

61 251&255 Hwy, Natchez, MS 39120

Value Estimation by Request
2,000 sqft 0.51 AC lot
View details
255 Us-61
Individual retail properties

255 Us-61, Natchez, MS 39120

Value Estimation by Request
19,434 sqft 4.80 AC lot
View details
235 Highway 61
Distribution properties

235 Highway 61, Natchez, MS 39120

Value Estimation by Request
2,450 sqft 0.88 AC lot
View details
Shields Ln
STORE/OFFICE (MIXED USE)

Shields Ln, Natchez, MS 39120

$555,000
Estimated value
4,400 sqft 1.05 AC lot
View details
270 Sgt Prentiss Dr
STORE/OFFICE (MIXED USE)

270 Sgt Prentiss Dr, Natchez, MS 39120

$240,000
Estimated value
979 sqft 0.52 AC lot
View details
49 Sgt Prentiss Dr
STORE/OFFICE (MIXED USE)

49 Sgt Prentiss Dr, Natchez, MS 39120-4727

$465,000
Estimated value
15,027 sqft 1.77 AC lot
View details

Natchez, MS Mixed-Use Properties Market Trends and Statistics

Explore 55 mixed-use properties for sale in Natchez, MS, showcased through 8 active listings on our real estate platform. These investment opportunities span a total of 40,731 square feet of properties for sale, with an estimated market value of $3,943,500.

Sale prices for multi use buildings in Natchez, MS start at $275,000, averaging $492,937, and reaching up to $675,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

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Demographics Overview

Population 29K
Population Growth (5Y) -6.5%
Median Household Income $40,586
College Educated 9.0%

Taxes & Financing

Average Loan-to-Value 65.0%

Total CRE Inventory on Market (SF)

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