Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Mixed-Use
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Natchez, MS Mixed-use Properties for Sale

    Notify Me
    List
    Map
    Gulfport, MS Jackson, MS Hattiesburg, MS
    Downtown Natchez Mixed-Use Opportunity
    $875,000
    4,400 SF

    Downtown Natchez Mixed-Use Opportunity

    433 Main Street, Natchez, MS 39120

    Two-story historical building in downtown Natchez with commercial and residential potential.

    • Prime downtown location at the corner of Main Street & Commerce, Natchez, MS.
    • Versatile 2‑story historical building suitable for commercial and residential use.
    • Renovated 2nd level featuring two 2‑bedroom, 2‑bath units with included appliances.
    • Lower level offers great space for retail, office, or other commercial uses.
    • Recipient of a Historic Natchez Foundation Special Merit Award for renovation.
    Updated: Jun 20, 2025
    View details
    Thriving Event Venue & Wedding Barn
    $499,000
    5,000 SF

    Thriving Event Venue & Wedding Barn

    398 Greenfield Rd, Natchez, MS 39120

    Event venue on 3 acres, suitable for various events.

    • Thriving event venue with established business potential.
    • Approximately 3 picturesque acres in a private, wooded setting.
    • Over 5,000 square feet of versatile space under roof.
    • Suitable for weddings, special events, corporate retreats, and more.
    • Open‑concept event space with high ceilings and rustic charm.
    Updated: Feb 20
    View details
    Historic Kings Tavern Building
    $550,000
    5,396 SF

    Historic Kings Tavern Building

    Three-level antebellum structure with multi-use spaces and restaurant potential.

    613 Jefferson St, Natchez, MS 39120
    View details
    Versatile Building in Natchez, MS
    $185,000
    2,450 SF

    Versatile Building in Natchez, MS

    Well-located 2,450 SF building suitable for various commercial uses.

    245 US-61, Natchez, MS 39120
    View details
    Mixed-Use Property with Multiple Buildings
    $995,000
    19,434 SF

    Mixed-Use Property with Multiple Buildings

    4.8-acre property featuring six freestanding buildings, some currently rented.

    255 US-61, Natchez, MS 39120
    View details
    Based on your search, we've compiled 60 Potential Opportunities for your consideration. Besides 5 Active listings in Natchez, MS, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 47 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Historic Three-Story Building in McComb
    $259,500
    7,121 SF

    Historic Three-Story Building in McComb

    7,121 sq ft historic building in need of restoration.

    114 State Street, Mccomb, MS 39648
    View details
    Brookhaven Commercial Building For Sale
    $139,000
    2,058 SF

    Brookhaven Commercial Building For Sale

    Vintage commercial building with potential for retail, office, or mixed-use.

    444 E Monticello Street, Brookhaven, MS 39601
    View details
    Brookhaven Commercial Building For Sale
    $399,500
    2,762 SF

    Brookhaven Commercial Building For Sale

    Prime commercial building in Brookhaven, MS, suitable for various businesses.

    391 Brookhaven St, Brookhaven, MS 39601
    View details
    Versatile Commercial Building in McComb
    $140,000
    10,532 SF

    Versatile Commercial Building in McComb

    10,532 sq ft commercial building with multiple options.

    210 S Broad Way, Mccomb, MS 39666
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Brookhaven Commercial Land For Sale
    $3,450,000
    4.65 Acres

    Brookhaven Commercial Land For Sale

    Prime commercial land in high-traffic area near major retailers.

    1338b Brookway Boulevard, Brookhaven, MS 39601
    View details
    Prime Development Lot, McComb, MS
    $999,900
    16.87 Acres

    Prime Development Lot, McComb, MS

    16.87-acre commercial lot with high visibility and traffic.

    Pike Point Place, Mccomb, MS 39648
    View details
    Prime Commercial Land For Sale
    $199,000
    0.78 Acres

    Prime Commercial Land For Sale

    0.78-acre commercial land in high-traffic location near major retailers.

    Northwest Avenue, Mccomb, MS 39648
    View details
    Land in Master-Planned Community
    $117,500
    0.45 Acres

    Land in Master-Planned Community

    Residential land in Zachary, LA, within a master-planned community.

    19646 Barnett Rd, Zachary, LA 70791
    View details

    Explore Off-Market Properties in Natchez, MS

    Consider similar Off-Market properties in Natchez, MS. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    402 Main St

    402 Main St

    STORE/OFFICE (MIXED USE) • 2,271 SF
    Value Estimation by Request
    402 Main St, Natchez, MS 39120-3464
    View details
    303 Devereaux Dr

    303 Devereaux Dr

    STORE/OFFICE (MIXED USE) • 14,985 SF
    Value Estimation
    $1,530,000
    303 Devereaux Dr, Natchez, MS 39120-4207
    View details
    345 Devereaux Dr

    345 Devereaux Dr

    STORE/OFFICE (MIXED USE) • 20,356 SF
    Value Estimation
    $1,495,000
    345 Devereaux Dr, Natchez, MS 39120-4207
    View details
    412 Hwy 61st N

    412 Hwy 61st N

    STORE/OFFICE (MIXED USE) • 7,334 SF
    Value Estimation
    $755,000
    412 Hwy 61st N, Natchez, MS 39120-4200
    View details
    114 Northgate Rd

    114 Northgate Rd

    STORE/OFFICE (MIXED USE) • 11,160 SF
    Value Estimation
    $680,000
    114 Northgate Rd, Natchez, MS 39120-9161
    View details
    15 Spg St

    15 Spg St

    STORE/OFFICE (MIXED USE) • 3,150 SF
    Value Estimation by Request
    15 Spg St, Natchez, MS 39120-2838
    View details
    624 Hwy 61st N

    624 Hwy 61st N

    STORE/OFFICE (MIXED USE) • 4,219 SF
    Value Estimation by Request
    624 Hwy 61st N, Natchez, MS 39120-8405
    View details
    131 Winchester Rd

    131 Winchester Rd

    Multifamily properties • 6,676 SF
    Value Estimation by Request
    131 Winchester Rd, Natchez, MS 39120
    View details
    939 Us-61

    939 Us-61

    Individual retail properties • 3,000 SF
    Value Estimation by Request
    939 Us-61, Natchez, MS 39120
    View details
    245 Us-61

    245 Us-61

    Mixed-use properties • 2,450 SF
    Value Estimation by Request
    245 Us-61, Natchez, MS 39120
    View details
    61 251&255 Hwy

    61 251&255 Hwy

    Individual retail properties • 2,000 SF
    Value Estimation by Request
    61 251&255 Hwy, Natchez, MS 39120
    View details
    255 Us-61

    255 Us-61

    Individual retail properties • 19,434 SF
    Value Estimation by Request
    255 Us-61, Natchez, MS 39120
    View details
    235 Highway 61

    235 Highway 61

    Distribution properties • 2,450 SF
    Value Estimation by Request
    235 Highway 61, Natchez, MS 39120
    View details
    Shields Ln

    Shields Ln

    STORE/OFFICE (MIXED USE) • 4,400 SF
    Value Estimation
    $555,000
    Shields Ln, Natchez, MS 39120
    View details
    270 Sgt Prentiss Dr

    270 Sgt Prentiss Dr

    STORE/OFFICE (MIXED USE) • 979 SF
    Value Estimation by Request
    270 Sgt Prentiss Dr, Natchez, MS 39120
    View details
    49 Sgt Prentiss Dr

    49 Sgt Prentiss Dr

    STORE/OFFICE (MIXED USE) • 15,027 SF
    Value Estimation
    $1,545,000
    49 Sgt Prentiss Dr, Natchez, MS 39120-4727
    View details
    515 Rankin St

    515 Rankin St

    STORE/OFFICE (MIXED USE) • 4,436 SF
    Value Estimation by Request
    515 Rankin St, Natchez, MS 39120-2940
    View details
    122 Pilgrim Rd

    122 Pilgrim Rd

    STORE/OFFICE (MIXED USE) • 9,230 SF
    Value Estimation
    $740,000
    122 Pilgrim Rd, Natchez, MS 39120-2651
    View details
    613 Main St

    613 Main St

    STORE/OFFICE (MIXED USE) • 19,370 SF
    Value Estimation
    $705,000
    613 Main St, Natchez, MS 39120-3325
    View details

    Natchez, MS Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 52 mixed-use properties for sale in Natchez, MS, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 630,473 square feet of properties for sale, with an estimated market value of $3,605,000.

    Sale prices for multi use buildings in Natchez, MS start at $215,000, averaging $515,000, and reaching up to $1,240,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Popular Searches in Natchez, MS

    Popular Categories

    Most Searched ZIP Codes in Natchez, MS

    • 39120

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!