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    Natchez, MS
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    Natchez, MS Commercial Real Estate for Lease

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    Vidalia, LA North Tunica, MS Ferriday, LA
    6 results
    Retail Space in Natchez, MS
    $4,000/Mo
    4,000 SF

    Retail Space in Natchez, MS

    414 Hwy 61 N, Natchez, MS 39120

    4,000 sq ft retail space for rent in Natchez.

    • 4,000 sq ft space adaptable to two 2,000 sq ft spaces
    • Quoted rent includes a significant portion of Tenant Improvements
    • $4,000 per month rent
    • Flexible rental options (single or split space)
    • Tenant improvement cost negotiation possible
    Updated: Mar 6, 2025
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    Downtown Natchez Renovated Office Space
    $1,200/Mo
    1,200 SF

    Downtown Natchez Renovated Office Space

    104 S Wall St, Natchez, MS 39120

    Recently renovated office space for lease in downtown Natchez.

    • Utilities included in monthly rent.
    • Recently renovated office space.
    • Prime downtown Natchez location across from the courthouse.
    • Includes reception area, 2 offices, and a break room.
    • Approximately 1000‑1200 square feet of space.
    Updated: Oct 20, 2025
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    Northgate Shopping Center Retail Space
    $14 SF/Yr

    Northgate Shopping Center Retail Space

    Retail spaces available in Northgate Shopping Center.

    105 Northgate Road, Natchez, MS 39120
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    Medical Office Shell Space
    $20 SF/Yr
    3,080 SF

    Medical Office Shell Space

    3,080 SF shell space in Class A medical office.

    46 Sgt Prentiss Pkwy, Natchez, MS
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    Retail Space in Natchez Mall
    Contact for pricing
    3,500 SF

    Retail Space in Natchez Mall

    Retail space available in established Natchez Mall.

    350 John Junkin Drive, Natchez, MS
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    Medical Office Space Near Hospital
    $20 SF/Yr

    Medical Office Space Near Hospital

    Class A medical building adjacent to Merit Health Natchez hospital.

    46 Sgt Prentiss Dr, Natchez, MS 39120
    View details
    Based on your search, we've compiled 71 Potential Opportunities for your consideration. Besides 6 Active listings in Natchez, MS, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 61 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Medical Plaza Office Space Available
    $23 SF/Yr
    12,000 SF

    Medical Plaza Office Space Available

    Up to 12,000 SF available in medical plaza.

    107 Front Street, Vidalia, LA 71373
    View details
    Office Space for Lease
    $1,700/Mo
    1,200 SF

    Office Space for Lease

    Office space featuring multiple rooms available for lease.

    425 Highway 51 N, Brookhaven, MS 39601
    View details
    Brookhaven Retail Space Available
    $10 SF/Yr
    2,667 SF

    Brookhaven Retail Space Available

    Retail space available for lease in Brookhaven, Mississippi.

    830-844 Brookway Blvd, Brookhaven, MS
    View details
    Former Restaurant with Drive-Thru
    $18 SF/Yr
    2,913 SF

    Former Restaurant with Drive-Thru

    2,913 SF former Burger King with drive-thru and pylon signage.

    1115 Carter St, Vidalia, LA 71373
    View details

    Similar Spaces for Sale in Natchez, MS

    Consider Similar Space for Sale. We found 61 Spaces matching your search parameters.

    Natchez Commercial Property For Sale
    $2,355,000
    24,060 SF

    Natchez Commercial Property For Sale

    Two office buildings on 3.44 acres with flexible spaces.

    131 Jefferson Davis Boulevard, Natchez, MS 39120
    View details
    Natchez Medical Facility For Sale
    $275,000
    4,583 SF

    Natchez Medical Facility For Sale

    Over 4,500 SF commercial building in Natchez, Mississippi.

    500 N Martin Luther King Street, Natchez, MS 39120
    View details
    Commercial Property in Natchez, MS
    $125,000
    1,614 SF

    Commercial Property in Natchez, MS

    Commercial property with 1614 square feet on 0.3 acres.

    104 Homochitto Street, Natchez, MS 39120
    View details
    Turnkey Car Wash Package Sale
    $6,500,000
    3,529 SF

    Turnkey Car Wash Package Sale

    Two car wash locations sold as a package in Natchez, MS.

    273 John R Junkin Drive, Natchez, MS 39120
    View details
    Historic Natchez Office Building
    $495,000
    9,500 SF

    Historic Natchez Office Building

    Two-story commercial building in downtown Natchez with investment potential.

    126 S Commerce Street, Natchez, MS 39120
    View details
    Natchez Commercial Building For Sale
    $375,000
    6,780 SF

    Natchez Commercial Building For Sale

    Commercial building in high-visibility area with reliable tenants.

    55 E Franklin Street lot: B, Natchez, MS 39120
    View details
    Commercial Building with Potential Uses
    $225,000
    3,750 SF

    Commercial Building with Potential Uses

    Commercial building with potential for various uses in Natchez, MS.

    335 Lower Woodville Road, Natchez, MS 39120
    View details
    Commercial Building with High Potential
    $210,000
    3,204 SF

    Commercial Building with High Potential

    Spacious brick building in high-traffic area, suitable for various uses.

    329 Lower Woodville Road, Natchez, MS 39120
    View details
    Prime Commercial Lot on Junkin
    $495,000
    0.73 Acres

    Prime Commercial Lot on Junkin

    High-traffic lot with potential for various commercial uses.

    465 John R Junkin Drive, Natchez, MS 39120
    View details
    Commercial Building in High Traffic Area
    $135,000
    1,280 SF

    Commercial Building in High Traffic Area

    Metal building with easy access and parking in Natchez.

    327 Lower Woodville Road, Natchez, MS 39120
    View details
    Downtown Natchez Mixed-Use Opportunity
    $875,000
    4,400 SF

    Downtown Natchez Mixed-Use Opportunity

    Two-story historical building in downtown Natchez with commercial and residential potential.

    433 Main Street, Natchez, MS 39120
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    9.6 Acre Commercial Land Tract
    $995,000
    9.60 Acres

    9.6 Acre Commercial Land Tract

    9.6 acre commercial land in Natchez, MS for sale.

    129 Jeff Davis Boulevard, Natchez, MS 39120
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    Turn-Key Automotive Detail Shop
    $199,000
    1,720 SF

    Turn-Key Automotive Detail Shop

    Automotive detail shop with equipment in Natchez, Mississippi.

    1169 Dr. Martin Luther King Jr., Natchez, MS 39120
    View details
    Commercial Lot in High-Traffic Area
    $165,000

    Commercial Lot in High-Traffic Area

    Commercial lot in high-traffic area with good visibility.

    Sergeant Prentiss Drive, Natchez, MS 39120
    View details
    Natchez Commercial Property with Warehouses
    $419,000
    10,656 SF

    Natchez Commercial Property with Warehouses

    Commercial property with two warehouses, near Highway 61 South.

    18 Col. John Pitchford Parkway, Natchez, MS 39120
    View details
    Versatile Commercial Property with Warehouse
    $205,000
    2,450 SF

    Versatile Commercial Property with Warehouse

    Commercial property featuring offices and a large warehouse area.

    235 Highway 61, Natchez, MS 39120
    View details
    KFC Drive-Thru Restaurant Investment
    Contact for pricing
    3,528 SF

    KFC Drive-Thru Restaurant Investment

    NNN leased KFC on 1.10 acres with drive-thru.

    24 Sgt Prentiss Dr, Natchez, MS 39120
    View details
    Thriving Event Venue & Wedding Barn
    $499,000
    5,000 SF

    Thriving Event Venue & Wedding Barn

    Event venue on 3 acres, suitable for various events.

    398 Greenfield Rd, Natchez, MS 39120
    View details

    Natchez, MS Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Natchez, MS with 6 listings featured on our commercial real estate exchange. The current inventory includes 10,330 square feet of properties with an estimated lease value of $76 SF/Yr.

    Estimated lease rates for Commercial real estate in Natchez, MS begin at $12 SF/Yr, with an average of $15 SF/Yr and extend to $20 SF/Yr.
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