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Downtown San Francisco, CA Office Spaces for Sale

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Daly City, CA Brisbane, CA Alameda, CA Sausalito, CA Oakland, CA Tiburon, CA Colma, CA South San Francisco, CA
15 properties
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Mixed-Use Building in Prime Location
Updated: Dec 14, 2025
Mixed-Use Building in Prime Location

450 Grant Avenue, San Francisco, CA 94108

$5,200,000
13,950 sqft 0.11 AC lot
Prime corner location at the gateway to Chinatown and steps from the Financial District.
Mixed‑use building with three ground floor retail units, three office suites, and five renovated apartments.
High visibility and continuous pedestrian traffic in a dynamic, high‑demand corridor.
Close proximity to Saint Mary's Square, Union Square, world‑class shopping, restaurants, hotels, and major transit lines.
Income‑producing asset with huge growth potential.
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This listing looks promising.

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450 Grant Avenue, San Francisco, CA 94108

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Two-Story Commercial Building
Updated: Sep 21, 2025
Two-Story Commercial Building

729 Bush Street, San Francisco, CA 94108

$2,795,000
5,072 sqft 0.09 AC lot
Two‑story commercial building plus basement, built in 1911
Approximately 5,072 sq ft building area on a 3,781‑sq ft lot
RC‑4 zoning allows a wide range of commercial uses (showroom, upscale office, medical, or specialized retail)
Commercial asset located in San Francisco’s Lower Nob Hill/Downtown area near Union Square and the Financial District
Served by BART, cable cars, and MUNI, with nearby major downtown destinations including Salesforce Tower
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Office Space with Reception Area
Office Space with Reception Area

San Francisco, CA 94111

$995,000
1,962 sqft

Office unit featuring six offices, reception, and restroom.

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Medical Office Space for Sale
Medical Office Space for Sale

133 Kearny Street, San Francisco, CA 94108

$380,000
24,759 sqft

Medical-focused office space available for sale in San Francisco, suited for practices seeking a dedicated work environment.

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South of Market Full Building
South of Market Full Building

667 Howard Street, San Francisco, CA 94105

$12,000,000
12,000 sqft

12,000 SF building in the heart of South of Market.

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High-End Office Space
High-End Office Space

San Francisco, CA 94104

Contact for pricing
25,643 sqft

Offered for sale and marketed for lease as high-end office space at 180 Sutter St in San Francisco.

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Mixed-Use Retail and Creative Office Portfolio
Mixed-Use Retail and Creative Office Portfolio

165 Post St, San Francisco, CA 94108

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73,374 sqft

Two-building portfolio combining ground-floor retail with creative office space above, offered for sale at scale.

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Class A Office Space
Class A Office Space

San Francisco, CA 94108

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133,348 sqft

Class A office space for lease in San Francisco, offered for sale.

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Office Space with Exposed Brick
Office Space with Exposed Brick

San Francisco, CA 94105

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14,800 sqft

Office space featuring high ceilings and exposed brick.

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Renovated Office Building For Rent
Renovated Office Building For Rent

San Francisco, CA 94105

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23,904 sqft

LEED Silver certified office building with modern upgrades available for lease.

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Modern Office Space on Maiden
Modern Office Space on Maiden

San Francisco, CA 94108

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52,291 sqft

Office space with new lobby and operable windows for rent.

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Office Building in San Francisco
Office Building in San Francisco

San Francisco, CA 94105

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28,000 sqft

Office building with 28,000 square feet available for rent.

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Creative Brick and Timber Space
Creative Brick and Timber Space

San Francisco, CA 94105

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16,000 sqft

Creative brick and timber full floor available for rent.

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San Francisco Office Space
San Francisco Office Space

San Francisco, CA 94105

Contact for pricing
419,371 sqft

Office building in San Francisco, CA with 419371 square feet.

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San Francisco Office Building For Sale
San Francisco Office Building For Sale

924 Sansome St, San Francisco, CA 94111

$5,800,000
19,212 sqft

Office building with 19,212 square feet available for sale.

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Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 15 Active listings in Downtown San Francisco, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 57 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Oakland Office Building For Sale
Oakland Office Building For Sale

725 Washington Street, Oakland, CA 94607

$2,130,000
7,753 sqft

7,753 SF office building in Oakland, California.

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Sausalito Office Building For Sale
Sausalito Office Building For Sale

900 Bridgeway, Sausalito, CA 94965

Contact for pricing
6,716 sqft

6,716 SF office building in prime Sausalito location.

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Sausalito Mixed-Use Investment Opportunity
Sausalito Mixed-Use Investment Opportunity

219 Caledonia, Sausalito, CA 94965

$2,287,000
3,474 sqft

Charming mixed-use property in Sausalito with retail and office spaces.

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Oakland Office Building Investment Opportunity
Oakland Office Building Investment Opportunity

737 2Nd St # 101 #101, Oakland, CA 94607

$599,000
3,441 sqft

Historic Oakland building, renovated, ideal for office or investment.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

El Sobrante Land Opportunity
El Sobrante Land Opportunity

425 Appian Way, El Sobrante, CA 94803

$1,350,000
10,000 sqft

Commercial land available off San Pablo Dam Road.

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Prime Corner Lot in Burlingame
Prime Corner Lot in Burlingame

Hillsborough, CA 94010

$11,500,000
11,000 sqft 0.65 AC lot

Iconic building site with development potential near downtown.

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Corner Lot Near Downtown
Corner Lot Near Downtown

310 310 Central Ave, Pittsburg, CA 94565

$1,650,000

Commercial land near downtown and E-Bart Station.

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Commercial Parcel in Livermore Hub
Commercial Parcel in Livermore Hub

2901 Las Positas Road, Livermore, CA 94551

$1,900,000
0.93 AC lot

Prime commercial land in established retail and service hub.

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Off-Market Properties in Downtown San Francisco, CA

Consider similar Off-Market properties in Downtown San Francisco, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

216 Pne St
OFFICE BUILDING

216 Pne St, San Francisco, CA 94104

$8,465,000
Estimated value
46,225 sqft 0.14 AC lot
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505 Montgomery St
OFFICE BUILDING

505 Montgomery St, San Francisco, CA 94111-6529

Value Estimation by Request
0.02 AC lot
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245 Post St, Unit 253
OFFICE BUILDING

245 Post St, San Francisco, CA 94108-5012

Unit 253
Value Estimation by Request
37,088 sqft 0.16 AC lot
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640 Sacramento St
OFFICE BUILDING

640 Sacramento St, San Francisco, CA 94111-2510

$5,770,000
Estimated value
32,564 sqft 0.19 AC lot
View details
1045 Sansome St
OFFICE BUILDING

1045 Sansome St, San Francisco, CA 94111-1311

$25,580,000
Estimated value
89,010 sqft 0.87 AC lot
View details
1 Frnt St
OFFICE BUILDING

1 Frnt St, San Francisco, CA 94111-5325

$3,015,000
Estimated value
605,459 sqft 0.63 AC lot
View details
88 Kearny St
OFFICE BUILDING

88 Kearny St, San Francisco, CA 94108-5530

$4,760,000
Estimated value
260,624 sqft 0.05 AC lot
View details
88 Kearny St
OFFICE BUILDING

88 Kearny St, San Francisco, CA 94108-5530

$4,735,000
Estimated value
260,624 sqft 0.05 AC lot
View details
88 Kearny St
OFFICE BUILDING

88 Kearny St, San Francisco, CA 94108-5530

$4,790,000
Estimated value
260,624 sqft 0.03 AC lot
View details

Downtown San Francisco, CA Office Spaces Market Trends and Statistics

Explore 72 office spaces for sale in Downtown San Francisco, CA, showcased through 15 active listings on our real estate platform. These investment opportunities span a total of 745,351 square feet of properties for sale, with an estimated market value of $319,817,176.

Sale prices for office spaces in Downtown San Francisco, CA start at $333,000, averaging $3,438,894, and reaching up to $38,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 528
Office buildings 132
Creative space 91
Medical Office Space 31
Coworking space 24

Demographics Overview

Population 836K
Population Growth (5Y) -3.0%
Median Household Income $143,518
College Educated 35.9%

High-Yield Neighborhoods for Investment

Identify San Francisco submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
94112 $699.5K
94114 $1.1M
94131 $1.4M
94121 $1.5M
94116 $1.7M

Taxes & Financing

Tax Rate (average for all types) 1.18%
Property Tax per SF $3.84 per SF
Tax Rate vs County Average 0.01 pp below county avg
Average Loan-to-Value 65.0%

Property Size Breakdown

The majority of commercial real estate listings in San Francisco fall within the 10,000 to 25,000 square foot range.

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