Downtown San Francisco, CA Commercial Real Estate for Sale

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Two-Story Retail Building
Updated: Sep 21, 2025
Two-Story Retail Building

729 Bush Street, San Francisco, CA 94108

$2,795,000
5,072 sqft 0.09 AC lot
Approximately 5,072 square feet of building area on a 3,781‑square‑foot lot
Two‑story building with basement; constructed in 1911
RC‑4 zoning supports showroom, upscale office, medical, and specialized retail uses
729 Bush Street address in San Francisco’s Lower Nob Hill/Downtown area
Near Union Square and the Financial District
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Single-Tenant Retail Storefront
Updated: Oct 14
Single-Tenant Retail Storefront

433 Grant Avenue, San Francisco, CA 94108

$2,250,000
3,674 sqft 0.05 AC lot
3,674 square feet of rentable area
Additional 2,000‑square‑foot lower level used for storage
2,062.5‑square‑foot parcel
Single‑tenant storefront with Grant Avenue frontage
Built in 1922
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Single-Tenant Retail Storefront
Single-Tenant Retail Storefront

A-1158 Sutter St, San Francisco, CA 94104

$568,000
637 sqft

Street-level retail unit with an open floor plan, ADA bathroom, and customer access directly from the sidewalk.

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See hot listings in San Francisco

Scored against comparables nationwide. These are worth a look.

Scored against comparables nationwide. These are worth a look.

Cap Rate available after sign in
Est. NOI available after sign in
Local Demand available after sign in
Two-Story Creative Office Space
Two-Story Creative Office Space

72 Tehama Street, San Francisco, CA 94105

$2,995,000
3,625 sqft

Existing build-out offers commercial functionality with potential for residential or live-work conversion.

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Two Office Condos with En-Suite Baths
Two Office Condos with En-Suite Baths

406-7-950 Stockton St, San Francisco, CA 94108

$500,000
1,845 sqft

Adjacent units provide flexible layouts for owner occupancy or leasing.

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Retail or Office Condominium Suite
Retail or Office Condominium Suite

400 Beale Street, San Francisco, CA 94105

$1,250,000
1,469 sqft

Commercial condominium suite features ADA-compliant entrance and restrooms plus one secured parking space.

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Office Condo with En-Suite Bath
Office Condo with En-Suite Bath

407-950 Stockton St, San Francisco, CA 94108

$288,000
1,021 sqft

Move-in-condition office condo with flexible workspace and access to professional, office, and buyer-verified medical uses.

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Office Condo Suite with En-Suite
Office Condo Suite with En-Suite

406-950 Stockton St, San Francisco, CA 94108

$248,000
824 sqft

Move-in condition office condo features a large open area, two private offices, and a private en-suite bath.

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Two-Story Commercial Building
Two-Story Commercial Building

729 Bush Street, San Francisco, CA 94108

$2,795,000
5,072 sqft 0.09 AC lot

Two-story building with basement and RC-4 zoning, supporting showroom, office, medical, and specialized retail uses.

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Mixed-Use Building in Prime Location
Mixed-Use Building in Prime Location

450 Grant Avenue, San Francisco, CA 94108

$5,200,000
13,950 sqft 0.11 AC lot

Mixed-use building with retail, office, and residential units.

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Mixed-Use Building with Ground Retail
Mixed-Use Building with Ground Retail

670 Commercial ST, San Francisco, CA 94111

$3,100,000
4,464 sqft

Mixed-use building with residential units above a ground-floor commercial space, including multiple electrical meter panels and water heaters.

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Renovated Storefront Building
Renovated Storefront Building

310 Sutter St, San Francisco, CA 94108

Contact for pricing
6,667 sqft

Vacant retail property with elevator access, updated interiors, and additional basement space.

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Ground-Level Office Suite
Ground-Level Office Suite

17-1155 Pine St, San Francisco, CA 94111

$895,000
2,627 sqft

Ground-level office suite with five private offices, open work areas, reception, kitchenette, and bathroom.

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High-End Office Space
High-End Office Space

San Francisco, CA 94104

Contact for pricing
25,643 sqft

Offered for sale and marketed for lease as high-end office space at 180 Sutter St in San Francisco.

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Office Building with Subterranean Parking
Office Building with Subterranean Parking

550 Kearny St, San Francisco, CA 94104

Contact for pricing
193,045 sqft

Office building featuring a 150-stall subterranean parking facility in San Francisco’s North Financial District.

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34-Unit Mixed-Use Apartment Building
34-Unit Mixed-Use Apartment Building

637 Bush Street, San Francisco, CA 94108

$6,800,000
16,824 sqft

The property combines 32 residential units with two commercial spaces in a centrally located San Francisco building.

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34-Unit Mixed-Use Property
34-Unit Mixed-Use Property

637-639 Bush Street, San Francisco, CA 94108

Contact for pricing
16,824 sqft

Historic apartment property with two commercial spaces, elevator service, secure entry, and a balanced studio and one-bedroom layout.

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Renovated Office Building For Rent
Renovated Office Building For Rent

San Francisco, CA 94105

Contact for pricing
23,904 sqft

LEED Silver certified office building with modern upgrades available for lease.

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Modern Office Space on Maiden
Modern Office Space on Maiden

San Francisco, CA 94108

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52,291 sqft

Office space with new lobby and operable windows for rent.

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Office Building in San Francisco
Office Building in San Francisco

San Francisco, CA 94105

Contact for pricing
28,000 sqft

Office building with 28,000 square feet available for rent.

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Creative Brick and Timber Space
Creative Brick and Timber Space

San Francisco, CA 94105

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16,000 sqft

Creative brick and timber full floor available for rent.

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Four-Unit Retail Building with Former Restaurant
Four-Unit Retail Building with Former Restaurant

522 Grant Avenue, San Francisco, CA 94108

$2,500,000

Four-unit retail property with three ground-floor shops and a former restaurant space on upper levels.

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San Francisco Office Space
San Francisco Office Space

San Francisco, CA 94105

Contact for pricing
419,371 sqft

Office building in San Francisco, CA with 419371 square feet.

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Mixed-Use Building with Rooftop Deck
Mixed-Use Building with Rooftop Deck

653-655 Commercial St, San Francisco, CA 94111

Contact for pricing
7,057 sqft

Mixed-use building with fully equipped bar/restaurant, nightclub, and creative office penthouse with private rooftop deck.

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Downtown San Francisco, CA Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Downtown San Francisco, CA, showcased through 31 active listings on our real estate platform. These investment opportunities span a total of 5,422,545 square feet of properties for sale, with an estimated market value of $816,003,607.

Sale prices for business properties in Downtown San Francisco, CA start at $50,000, averaging $2,914,298, and reaching up to $58,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 836K
Population Growth (5Y) -3.0%
Median Household Income $143,518
College Educated 35.9%

High-Yield Neighborhoods for Investment

Identify San Francisco submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
Daly City - 94013 $595K
San Francisco - 94102 $2.4M

Taxes & Financing

Tax Rate (average for all types) 1.18%
Property Tax per SF $3.84 per SF
Tax Rate vs County Average 0.01 pp below county avg
Average Loan-to-Value 65.0%

Property Size Breakdown

The majority of commercial real estate listings in San Francisco fall within the 10,000 to 25,000 square foot range.

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