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    Downtown San Francisco, CA Commercial Real Estate for Sale

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    Mixed-Use Building in Prime Location
    Updated: Dec 14, 2025
    Mixed-Use Building in Prime Location

    450 Grant Avenue, San Francisco, CA 94108

    $5,200,000
    13,950 sqft 0.11 AC lot
    Prime corner location at the gateway to Chinatown and steps from the Financial District.
    Mixed‑use building with three ground floor retail units, three office suites, and five renovated apartments.
    High visibility and continuous pedestrian traffic in a dynamic, high‑demand corridor.
    Close proximity to Saint Mary's Square, Union Square, world‑class shopping, restaurants, hotels, and major transit lines.
    Income‑producing asset with huge growth potential.
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    This listing looks promising.

    Here's a quick look at some key insights for

    450 Grant Avenue, San Francisco, CA 94108

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    • Est. Cap Rate

      8.7%
      Above avg (5.9%)

    • Est. NOI

      $453K
      Annual

    • Price @ 7% Cap

      $6.47M
      Above asking

    • Property Type

      Retail Stores
      Built 1921
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    Turn-Key Hair & Scalp Spa
    Updated: Jun 1
    Turn-Key Hair & Scalp Spa

    615 Kearny Street, San Francisco, CA 94108

    $350,000
    1,000 sqft
    Hair & Scalp spa business for sale, fully equipped with furniture, fixtures, equipment, and included business assets
    Training can be provided to support a smooth transition for the new owner‑operator or investor
    Modern interior with treatment rooms and a welcoming client space
    Tile flooring
    Year built: 2024
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    Two-Story Commercial Building
    Two-Story Commercial Building

    729 Bush Street, San Francisco, CA 94108

    $2,795,000
    5,072 sqft 0.09 AC lot

    Two-story building with basement, located near Downtown transit and offered for sale in an RC-4 flexible-use zone.

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    Single-Tenant Retail Storefront
    Single-Tenant Retail Storefront

    A-1158 Sutter St, San Francisco, CA 94104

    $568,000
    637 sqft

    Street-level retail unit with an open floor plan, ADA bathroom, and customer access directly from the sidewalk.

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    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Former Tuxedo Building on Kearny
    Former Tuxedo Building on Kearny

    227 Kearny Street, San Francisco, CA 94108

    $2,999,999
    4,727 sqft 0.04 AC lot

    Three-story building with a basement in a vibrant area.

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    Mixed-Use Building with Retail and Apartments
    Mixed-Use Building with Retail and Apartments

    706 Sacramento Street, San Francisco, CA 94108

    $2,500,000
    6,720 sqft

    Three-story mixed-use building with two ground-floor retail spaces, six apartments, and a vacant basement with separate entrance.

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    Three-Story Office Building
    Three-Story Office Building

    227-231 Kearny Street, San Francisco, CA 94108

    $2,999,999
    4,727 sqft

    Former tuxedo building with three occupied floors plus a large basement, each with private bathrooms and hardwood floors.

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    Move-In Office Condo Suite
    Move-In Office Condo Suite

    950 Stockton Street Unit 406, San Francisco, CA 94108

    $248,000
    824 sqft

    Interior office condo with a large open area and two private offices, including a private en-suite bath.

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    Office Condo Suite with En-Suite
    Office Condo Suite with En-Suite

    406-950 Stockton St, San Francisco, CA 94108

    $248,000
    824 sqft

    Move-in condition office condo features a large open area, two private offices, and a private en-suite bath.

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    Medical Office Space for Sale
    Medical Office Space for Sale

    133 Kearny Street, San Francisco, CA 94108

    $380,000
    24,759 sqft

    Medical-focused office space available for sale in San Francisco, suited for practices seeking a dedicated work environment.

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    South of Market Full Building
    South of Market Full Building

    667 Howard Street, San Francisco, CA 94105

    $12,000,000
    12,000 sqft

    12,000 SF building in the heart of South of Market.

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    Ground-Level Office Suite
    Ground-Level Office Suite

    17-1155 Pine St, San Francisco, CA 94111

    $895,000
    2,627 sqft

    Ground-level office suite with five private offices, open work areas, reception, kitchenette, and bathroom.

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    Two-Story Commercial Building
    Two-Story Commercial Building

    729 Bush Street, San Francisco, CA 94108

    $2,795,000
    5,072 sqft 0.09 AC lot

    Two-story building with basement and RC-4 zoning, supporting showroom, office, medical, and specialized retail uses.

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    High-End Office Space
    High-End Office Space

    San Francisco, CA 94104

    Contact for pricing
    25,643 sqft

    Offered for sale and marketed for lease as high-end office space at 180 Sutter St in San Francisco.

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    Mixed-Use Retail and Creative Office Portfolio
    Mixed-Use Retail and Creative Office Portfolio

    165 Post St, San Francisco, CA 94108

    Contact for pricing
    73,374 sqft

    Two-building portfolio combining ground-floor retail with creative office space above, offered for sale at scale.

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    Class A Office Space
    Class A Office Space

    San Francisco, CA 94108

    Contact for pricing
    133,348 sqft

    Class A office space for lease in San Francisco, offered for sale.

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    Mixed-Use Building with Ground Retail
    Mixed-Use Building with Ground Retail

    670-674 Commercial Street, San Francisco, CA 94111

    $3,100,000
    4,464 sqft

    Mixed-use property with residential units above ground-floor commercial space and multiple electrical meter panels and water heaters.

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    Office Space with Exposed Brick
    Office Space with Exposed Brick

    San Francisco, CA 94105

    Contact for pricing
    14,800 sqft

    Office space featuring high ceilings and exposed brick.

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    Renovated Office Building For Rent
    Renovated Office Building For Rent

    San Francisco, CA 94105

    Contact for pricing
    23,904 sqft

    LEED Silver certified office building with modern upgrades available for lease.

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    Modern Office Space on Maiden
    Modern Office Space on Maiden

    San Francisco, CA 94108

    Contact for pricing
    52,291 sqft

    Office space with new lobby and operable windows for rent.

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    Office Building in San Francisco
    Office Building in San Francisco

    San Francisco, CA 94105

    Contact for pricing
    28,000 sqft

    Office building with 28,000 square feet available for rent.

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    Creative Brick and Timber Space
    Creative Brick and Timber Space

    San Francisco, CA 94105

    Contact for pricing
    16,000 sqft

    Creative brick and timber full floor available for rent.

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    San Francisco Office Space
    San Francisco Office Space

    San Francisco, CA 94105

    Contact for pricing
    419,371 sqft

    Office building in San Francisco, CA with 419371 square feet.

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    Four-Unit Retail Building with Former Restaurant
    Four-Unit Retail Building with Former Restaurant

    522 Grant Avenue, San Francisco, CA 94108

    $2,500,000

    Four-unit retail property with three ground-floor shops and a former restaurant space on upper levels.

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    Downtown San Francisco, CA Commercial Real Estate Market Trends and Statistics

    Explore 72 commercial real estate for sale in Downtown San Francisco, CA, showcased through 31 active listings on our real estate platform. These investment opportunities span a total of 1,648,540 square feet of properties for sale, with an estimated market value of $766,411,111.

    Sale prices for business properties in Downtown San Francisco, CA start at $50,000, averaging $2,914,110, and reaching up to $38,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 836K
    Population Growth (5Y) -3.0%
    Median Household Income $143,518
    College Educated 35.9%

    High-Yield Neighborhoods for Investment

    Identify San Francisco submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    Canton $1.2M
    San Francisco $2.8M

    Taxes & Financing

    Tax Rate (average for all types) 1.18%
    Property Tax per SF $3.84 per SF
    Tax Rate vs County Average 0.01 pp below county avg
    Average Loan-to-Value 65.0%

    Property Size Breakdown

    The majority of commercial real estate listings in San Francisco fall within the 10,000 to 25,000 square foot range.

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    Most Searched ZIP Codes in San Francisco, CA

    • 94108
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    • 94111
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