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    Downtown San Francisco, CA Commercial Real Estate for Sale

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    Daly City, CA Brisbane, CA Colma, CA
    13 results
    Commercial Asset in Lower Nob Hill
    $2,795,000
    3,795 SF

    Commercial Asset in Lower Nob Hill

    729 Bush Street, San Francisco, CA 94108

    Two-story commercial building with redevelopment potential near Union Square.

    • Prime location in San Francisco's Lower Nob Hill/Downtown, near Union Square and the Financial District, offering high foot traffic and visibility.
    • Flexible RC‑4 zoning allows for a wide range of commercial uses.
    • Significant redevelopment potential, including vertical expansion and modern medical build‑outs.
    • Large 3,781‑sq ft lot, a rare find in this area.
    • Excellent transportation access via BART, cable cars, and MUNI.
    Updated: Sep 21, 2025
    View details
    San Francisco Mixed-Use Investment Property
    $1,650,000
    0.02 Acres

    San Francisco Mixed-Use Investment Property

    550-552 Grant Avenue, San Francisco, CA 94108

    Mixed-use property in San Francisco's Chinatown with retail and residential.

    • Prime location in San Francisco's Chinatown with high foot traffic.
    • Mixed‑use property suitable for investors or owner‑users.
    • Large retail storefront on Grant Avenue with mezzanine floor, waterbar, basement, office, and restroom.
    • Updated residential units: a 2‑bedroom/1‑bathroom unit and a 3‑bedroom/1.5‑bath unit.
    • Residential units face the park.
    Updated: Oct 15, 2025
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    Former Tuxedo Building on Kearny
    $2,999,999
    4,727 SF

    Former Tuxedo Building on Kearny

    Three-story building with a basement in a vibrant area.

    227 Kearny Street, San Francisco, CA 94108
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    Office Space with Reception Area
    $995,000
    1,962 SF

    Office Space with Reception Area

    Office unit featuring six offices, reception, and restroom.

    San Francisco, CA 94111
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    Downtown San Francisco Commercial Duplex
    $1,295,000
    2,192 SF

    Downtown San Francisco Commercial Duplex

    Inspiring space ideal for creative, retail, or professional use.

    767 Bush Street, San Francisco, CA 94108
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    Versatile Commercial Building in Nob Hill
    $2,795,000
    5,072 SF

    Versatile Commercial Building in Nob Hill

    Two-story commercial building with redevelopment potential in a prime location.

    729 Bush Street, San Francisco, CA 94108
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    Prime Retail Space Near Union
    Contact for pricing

    Prime Retail Space Near Union

    Retail property near Union Square with high visibility.

    311 Grant Avenue, San Francisco, CA 94108
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    Mixed-Use Building in Prime Location
    $5,200,000
    13,950 SF

    Mixed-Use Building in Prime Location

    Mixed-use building with retail, office, and residential units.

    450 Grant Avenue, San Francisco, CA 94108
    View details
    South of Market Full Building
    $12,000,000
    12,000 SF

    South of Market Full Building

    12,000 SF building in the heart of South of Market.

    667 Howard Street, San Francisco, CA 94105
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    Renovated Mixed-Use Property For Sale
    $2,999,000
    5,500 SF

    Renovated Mixed-Use Property For Sale

    Mixed-use property with residential and office units, renovated in 2023.

    883 Sacramento Street, San Francisco, CA 94108
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    Prime Chinatown Mixed-Use Investment
    $1,650,000
    0.02 Acres

    Prime Chinatown Mixed-Use Investment

    Mixed-use property in San Francisco's Chinatown with retail and residential.

    550 Grant Avenue, San Francisco, CA 94108
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    Mixed-Use Trophy Corner Building
    $8,500,000
    20,845 SF

    Mixed-Use Trophy Corner Building

    Mixed-use building with hotel and retail in Union Square.

    507 Bush Street, San Francisco, CA 94108
    View details
    San Francisco Office Building For Sale
    $5,800,000
    19,212 SF

    San Francisco Office Building For Sale

    Office building with 19,212 square feet available for sale.

    924 Sansome St, San Francisco, CA 94111
    View details
    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 13 Active listings in Downtown San Francisco, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 59 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Iconic Sausalito Building For Sale
    $2,799,000
    4,060 SF

    Iconic Sausalito Building For Sale

    Historic building in Sausalito with high pedestrian traffic.

    668 Bridgeway, Sausalito, CA 94965
    View details
    Sausalito Medical and Wellness Campus
    $2,849,999
    4,266 SF

    Sausalito Medical and Wellness Campus

    Two-building medical campus with garden and gated parking.

    111 2nd, Sausalito, CA 94965
    View details
    Vacant Land with High Visibility
    $8,000,000
    0.44 Acres

    Vacant Land with High Visibility

    19,300 SF vacant land with mixed-use zoning.

    2321 Geneva Avenue, Daly City, CA 94014
    View details
    Daly City Industrial Space
    $4,995,000
    14,200 SF

    Daly City Industrial Space

    14,200 SqFt industrial property available in Daly City, CA.

    3275 Geneva Ave, Daly City, CA 94014
    View details

    Off-Market Properties in Downtown San Francisco, CA

    Consider similar Off-Market properties in Downtown San Francisco, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    950 Stockton St Ste, Unit 206
    COMMERCIAL CONDOMINUIM
    1,279 SF
    Value Estimation by Request
    Unit 206

    950 Stockton St Ste, San Francisco, CA 94108-1619

    View details
    216 Pne St
    OFFICE BUILDING
    46,225 SF Lot: 0.14 Acres
    Estimated value
    $8,465,000

    216 Pne St, San Francisco, CA 94104

    View details
    201 Folsom St, Unit 27F
    APARTMENT HOUSE (5+ UNITS)
    1,191 SF
    Value Estimation by Request
    Unit 27F

    201 Folsom St, San Francisco, CA 94105-5082

    View details
    1100 Sacramento St
    APARTMENT HOUSE (5+ UNITS)
    76,783 SF Lot: 0.33 Acres
    Estimated value
    $2,185,000

    1100 Sacramento St, San Francisco, CA 94108-1918

    View details
    299 2nd St
    HOTEL
    320,256 SF Lot: 0.39 Acres
    Value Estimation by Request

    299 2nd St, San Francisco, CA 94105-3123

    View details
    440 Jackson St, Unit 444
    RETAIL STORES (PERSONAL SERVICES)
    3,040 SF Lot: 0.06 Acres
    Value Estimation by Request
    Unit 444

    440 Jackson St, San Francisco, CA 94111-1617

    View details
    201 Folsom St, Unit 12E
    APARTMENT HOUSE (5+ UNITS)
    1,366 SF
    Value Estimation by Request
    Unit 12E

    201 Folsom St, San Francisco, CA 94105-5069

    View details
    338 Main St, Unit 25D
    APARTMENT HOUSE (5+ UNITS)
    873 SF
    Estimated value
    $1,335,000
    Unit 25D

    338 Main St, San Francisco, CA 94105-2193

    View details
    1 Hawthorne St, Unit C1
    COMMERCIAL CONDOMINUIM
    2,693 SF
    Value Estimation by Request
    Unit C1

    1 Hawthorne St, San Francisco, CA 94105-3911

    View details
    505 Montgomery St
    OFFICE BUILDING
    Lot: 0.02 Acres
    Value Estimation by Request

    505 Montgomery St, San Francisco, CA 94111-6529

    View details
    637 Powell St, Unit 501
    RETAIL STORES (PERSONAL SERVICES)
    1,590 SF
    Value Estimation by Request
    Unit 501

    637 Powell St, San Francisco, CA 94108-3028

    View details

    Downtown San Francisco, CA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 72 commercial real estate for sale in Downtown San Francisco, CA, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 87,293 square feet of properties for sale, with an estimated market value of $44,383,999.

    Sale prices for business properties in Downtown San Francisco, CA start at $1,295,000, averaging $4,931,555, and reaching up to $12,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Property Size Breakdown

    The majority of commercial real estate listings in San Francisco fall within the 10,000 to 25,000 square foot range.

    Demographics Overview

    Population 836K
    Population Growth (5Y) -3.0%
    Median Household Income $143,518
    College Educated 35.9%

    High-Yield Neighborhoods for Investment

    Identify San Francisco submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    94134 $597.5K
    94131 $719K
    94121 $1M
    94112 $1.2M
    94132 $1.3M

    Taxes & Financing

    Tax Rate (average for all types) 1.18%
    Property Tax per SF $3.84 per sq ft
    Tax Rate vs County Average 0.01 pp below county avg
    Average Loan-to-Value 65.0%

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    Most Searched ZIP Codes in San Francisco, CA

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    • 94111
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