Advertise
    San Francisco, CA

    Downtown San Francisco, CA Commercial Real Estate for Lease

    Notify Me
    List
    Map
    South San Francisco, CA Daly City, CA Alameda, CA Brisbane, CA Oakland, CA Sausalito, CA Sacramento, CA Belvedere, CA
    849 properties
    Sort:
    Two-Story Storefront Building
    Updated: Aug 1, 2025
    Two-Story Storefront Building

    729 Bush Street, San Francisco, CA 94108

    $8,000/Mo
    5,072 sqft 0.09 AC lot
    Approximately 5,072 sq ft of building area on an approximately 3,781‑sq ft lot
    Two‑story storefront building with basement space
    RC‑4 zoning identified for showroom, office, medical, and specialized retail uses
    Built in 1911; includes three bathrooms
    729 Bush Street location near Union Square and the Financial District
    View details
    Medical Office Suite with Exam Rooms
    Updated: Aug 17
    Medical Office Suite with Exam Rooms

    210-2186 Geary Blvd, San Francisco, CA 94108

    $4,000/Mo
    1,052 sqft
    1,052‑square‑foot medical office suite in Unit 210
    Three exam rooms, two private offices, copy room, kitchen, and administrative work areas
    Reception and waiting area with abundant natural light
    One private internal bathroom plus two hallway bathrooms for patients
    Elevator access and on‑site parking options for patients and staff
    View details
    Ground-Level Office Units
    Ground-Level Office Units

    1621 Montgomery St, San Francisco, CA 94111

    $7,500/Mo
    7,500 sqft

    Flexible workspace includes private offices, meeting rooms, shared areas, and a kitchenette with HVAC service.

    View details
    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Retail Space with Elevators
    Retail Space with Elevators

    581 Market St, San Francisco, CA 94105

    $6,343/Mo
    8,709 sqft

    The space provides passenger and freight elevator access for retail operations.

    View details
    Medical Office Suite on Third Floor
    Medical Office Suite on Third Floor

    950 Stockton Street # 307, San Francisco, CA 94108

    $4,200/Mo
    1,142 sqft

    Third-floor suite offers private offices/exam rooms with built-in sink and cabinetry, plus shower/restroom access.

    View details
    3rd-Floor Medical Office Suite
    3rd-Floor Medical Office Suite

    307-950 Stockton St, San Francisco, CA 94108

    $4,200/Mo
    1,142 sqft

    Elevator-served 3rd-floor suite with private offices, exam rooms, and built-in sink areas plus a private shower/restroom.

    View details
    Move-In Ready Office Suite
    Move-In Ready Office Suite

    375-950 Stockton St, San Francisco, CA 94108

    $3,800/Mo
    690 sqft

    Bright, updated suite with corner windows and a reception plus two private offices for professional and service uses.

    View details
    Corner Office Suite with Reception
    Corner Office Suite with Reception

    950 Stockton Street # 375, San Francisco, CA 94108

    $3,800/Mo
    690 sqft

    Move-in ready office suite with reception area, two private offices, and corner windows in an elevator-served building.

    View details
    New-Frontage Retail Space
    New-Frontage Retail Space

    47 Geary St, San Francisco, CA 94108

    $1,743/Mo
    1,743 sqft

    Street-level retail premises with a recently installed storefront on Geary Street.

    View details
    Office Suite on Stockton Street
    Office Suite on Stockton Street

    950 Stockton Street 307, San Francisco, CA 94108

    $4,200/Mo
    1,142 sqft

    Office suite available for rent at 950 Stockton Street, Suite 307.

    View details
    Flexible workspace at CA, San Francisco - 388 Market Street. Contact us today to book a tour!
    View details
    Retail Space Near Apple Flagship
    Retail Space Near Apple Flagship

    278 Post St, San Francisco, CA 94108

    $4,153/Mo
    11,529 sqft

    The retail space is positioned near an Apple flagship and Stockton Street.

    View details
    Fully Serviced Business Solutions at CA, San Francisco - 101 Montgomery. Contact us today to book a tour!
    Fully Serviced Business Solutions at CA, San Francisco - 101 Montgomery. Contact us today to book a tour!

    101 Montgomery St, Unit 900, San Francisco, CA 94111

    15 available spaces from 11 to 1,676 sqft
    $129-$30,619/Mo per office

    Find fully flexible work and meeting space in CA, San Francisco - 101 Montgomery. Book a tour & get info

    View details
    Flexible Workspace Solutions at Spaces Levi's Plaza. Contact us today to book a tour!
    Flexible Workspace Solutions at Spaces Levi's Plaza. Contact us today to book a tour!

    1160 Battery St, San Francisco, CA 94111

    15 available spaces from 11 to 1,723 sqft
    $129-$17,496/Mo per office

    Find fully flexible work and meeting space in Spaces Levi's Plaza. Book a tour & get info

    View details
    Scalable Office Solutions at California Street. Contact us today to book a tour!
    Scalable Office Solutions at California Street. Contact us today to book a tour!

    50 California St, Unit 1500, San Francisco, CA 94111

    16 available spaces from 11 to 1,702 sqft
    $129-$33,696/Mo per office

    Flexible workspace in California Street. Book a tour & get info

    View details
    Office Unit with Conference Rooms
    Office Unit with Conference Rooms

    201 Mission St, San Francisco, CA 94105

    Contact for pricing
    8,601 sqft

    Layout includes an enclosed office, meeting rooms, a kitchen, storage, IT space, and an open work area.

    View details
    LEED-Certified Office Building
    LEED-Certified Office Building

    600 California Street, San Francisco, CA 94108

    Contact for pricing
    11,818 sqft

    Gold LEED certified office building with an efficient side-core layout and on-site parking for 200 vehicles.

    View details
    Office Units with Conference Rooms
    Office Units with Conference Rooms

    201 Mission St, San Francisco, CA 94105

    Contact for pricing
    8,456 sqft

    Flexible office layout with private window-line workspace, meeting rooms, kitchen, storage, and an open area.

    View details
    Office and Ground-Floor Retail Building
    Office and Ground-Floor Retail Building

    200 California St, San Francisco, CA 94111

    Contact for pricing
    6,502 sqft

    Boutique building built in 1988 with ground-floor retail street visibility and office space above.

    View details
    Multi-Level Retail Space
    Multi-Level Retail Space

    101-111 Geary St, San Francisco, CA 94108

    $760/Mo
    760 sqft

    The offering combines first-floor retail areas with an additional mezzanine component.

    View details
    Office Unit with Conference Rooms
    Office Unit with Conference Rooms

    201 Mission St, San Francisco, CA 94105

    Contact for pricing
    11,668 sqft

    Flexible office layout includes a private perimeter office, meeting rooms, kitchen, storage, and open workspace.

    View details
    Office Unit with Conference Rooms
    Office Unit with Conference Rooms

    201 Mission St, San Francisco, CA 94105

    Contact for pricing
    11,322 sqft

    Flexible office layout with private workspace, meeting rooms, kitchen facilities, and dedicated storage or IT space.

    View details
    Brand New Office Building with Roof Deck
    Brand New Office Building with Roof Deck

    350 Bush Street, San Francisco, CA 94104

    Contact for pricing
    4,183 sqft

    Brand new office building built in 2018 with a shared roof deck, side core, and a ground-floor event space.

    View details
    Office Suite with Private Offices
    Office Suite with Private Offices

    301 Howard Street, San Francisco, CA 94105

    Contact for pricing
    10,965 sqft

    Suite offers private offices, multiple conference rooms, and a kitchen/break area with garage parking.

    View details

    Downtown San Francisco, CA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Downtown San Francisco, CA with 849 listings featured on our commercial real estate exchange. The current inventory includes 24,822,847 square feet of properties with an estimated lease value of $3,385.

    Estimated lease rates for Commercial real estate in Downtown San Francisco, CA begin at $1.14 SF/Yr, with an average of $33.86 SF/Yr and extend to $85 SF/Yr.
    List
    Map

    Popular Categories

    Most Searched ZIP Codes in San Francisco, CA

    • 94105
    • 94104
    • 94111
    • 94108

    Featured San Francisco Real Estate Agencies

    Realmo connects you with licensed San Francisco CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Century 21 Baldini Realty
    4977 Mission St. San Francisco, CA 94112
    Phone: 14159394212
    C21Baldini.com
    Century 21 Realty Alliance
    1569 Sloat Blvd, Suite 300 San Francisco, CA 94132
    Phone: 14152131600
    www.c21realestate.com/
    Re/Max Prestigious Properties
    2811 14th Ave San Francisco, CA 94127
    Phone: 14155643776
    prestigiousproperties11.california.remax.com/

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!