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    Downingtown, PA
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    Downingtown, PA Office Properties & Spaces for Lease

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    Exton, PA West Chester, PA Coatesville, PA
    14 results
    Downingtown Commercial Space For Rent
    $6,000/Mo

    Downingtown Commercial Space For Rent

    45 W LANCASTER Avenue, Downingtown, PA 19335

    Versatile commercial property in Downingtown, ideal for various businesses.

    • Prime location in Downingtown, near Exton, Chester Springs, West Chester, and Malvern.
    • Flexible zoning suitable for retail, medical, daycare, salon/spa, health club, banquet facility, or warehouse.
    • Expansive open floor plan with HIGH 14' CEILINGS.
    • Approximately 29 parking spaces available.
    • Equipped with TWO LOADING DOCKS and 3‑phase electric.
    Updated: Aug 28, 2025
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    Downingtown Commercial Property For Rent
    $6,000/Mo

    Downingtown Commercial Property For Rent

    45 W Lancaster Ave, Downingtown, PA 19335

    Versatile commercial property suitable for retail, medical, daycare, or warehouse.

    • Prime location in Downingtown, near Exton, Chester Springs, West Chester, and Malvern.
    • Versatile commercial property with flexible zoning suitable for retail, medical, daycare, salon/spa, health club, banquet facility, or warehouse use.
    • Expansive open floor plan with soaring 14’ ceilings.
    • Approximately 29 parking spaces.
    • Equipped with two loading docks, 3‑phase electric, and HVAC.
    Updated: Aug 28, 2025
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    Downingtown Commercial Space for Lease
    $12,000/Mo
    7,500 SF

    Downingtown Commercial Space for Lease

    7,500 SF commercial space suitable for various ventures.

    20 COUNTRY CLUB DRIVE, Downingtown, PA 19335
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    Medical Office Space For Lease
    Contact for pricing
    10,500 SF

    Medical Office Space For Lease

    Medical office space available across from Thorndale Station.

    3025 Zinn Road, Thorndale, PA 19372
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    Furnished Office Sublease in Downingtown
    $650/Mo

    Furnished Office Sublease in Downingtown

    Fully furnished office space with utilities included in Downingtown, PA.

    4333 LINCOLN Highway E, Downingtown, PA 19335
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    Medical Office Space Available
    Contact for pricing
    10,500 SF

    Medical Office Space Available

    Medical office space for lease near Thorndale Station.

    Downingtown, PA 19372
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    Downingtown Office Space Available
    $18 SF/Yr
    6,868 SF

    Downingtown Office Space Available

    Office space featuring private offices and a large conference room.

    350 Marshallton Thorndale Rd, Downingtown, PA
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    Downingtown Office Space For Rent
    Contact for pricing
    3,800 SF

    Downingtown Office Space For Rent

    Office space in affluent area near Eagleview Corporate Center.

    164 Park Rd, Downingtown, PA
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    Downingtown Office Building with Drive-Thru
    Contact for pricing
    2,550 SF

    Downingtown Office Building with Drive-Thru

    Freestanding office building with drive-thru and dedicated parking.

    1201 E Lancaster Ave, Downingtown, PA
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    Redeveloped Downingtown Office and Retail
    Contact for pricing
    103,880 SF

    Redeveloped Downingtown Office and Retail

    Class A office and retail space in Downingtown, Pennsylvania.

    150 E Pennsylvania Ave, Downingtown, PA 19335
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    Scalable Medical Office Building
    Contact for pricing
    65,000 SF

    Scalable Medical Office Building

    Medical office building in Downingtown, PA, ranging from 30,000-65,000 SF.

    Route 322 and Boot Rd, Downingtown, PA 19335
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    Mixed-Use Complex on Lancaster Avenue
    Contact for pricing

    Mixed-Use Complex on Lancaster Avenue

    Mixed-use property featuring retail, office, and distribution spaces.

    520 E Lancaster Ave, Downingtown, PA 19335
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    Based on your search, we've compiled 27 Potential Opportunities for your consideration. Besides 14 Active listings in Downingtown, PA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Exton, PA - Fitted Office
    $66,000 SF/Yr
    2,400 SF

    Exton, PA - Fitted Office

    2400 SF fitted office space in Exton, PA.

    766 W LINCOLN Highway, Exton, PA 19341
    View details
    Commercial Office Condo For Lease
    $23 SF/Yr

    Commercial Office Condo For Lease

    Office space available for lease in Exton, Pennsylvania.

    780 W LINCOLN Highway, Exton, PA 19341
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    Office/Medical Space in Exton
    Contact for pricing

    Office/Medical Space in Exton

    Office/Medical space available in Oaklands Corporate Park, Exton, PA.

    460 Creamery Way, Exton, PA 19341
    View details
    Class A Office Building Rental
    Contact for pricing
    35,544 SF

    Class A Office Building Rental

    Prestigious office building with high-end finishes and convenient location.

    100 Arrandale Blvd, Exton, PA 19341
    View details

    Similar Spaces for Sale in Downingtown, PA

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Downingtown Commercial Property For Sale
    $850,000
    0.48 Acres

    Downingtown Commercial Property For Sale

    Versatile commercial building in prime location, ideal for various businesses.

    45 W LANCASTER Avenue, Downingtown, PA 19335
    View details
    Prime Commercial Property in THORNDALE
    $515,000
    0.23 Acres

    Prime Commercial Property in THORNDALE

    High-visibility commercial property in a desirable location, ideal for business.

    3532 LINCOLN Highway, Thorndale, PA 19372
    View details
    Downingtown Podcast Studio Opportunity
    Contact for pricing

    Downingtown Podcast Studio Opportunity

    Podcast studio space available in Downingtown with utilities included.

    4333 LINCOLN Highway E, Downingtown, PA 19335
    View details
    Downingtown Office Space Opportunity
    Contact for pricing

    Downingtown Office Space Opportunity

    Office and co-working spaces available in Downingtown, PA.

    4333 LINCOLN Highway E, Downingtown, PA 19335
    View details
    Thorndale Commercial Space on Lincoln Highway
    Contact for pricing

    Thorndale Commercial Space on Lincoln Highway

    Spacious commercial property suitable for retail, office, or business ventures.

    3629 E Lincoln Highway, Thorndale, PA 19372
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    2 Acre Land Parcel For Lease
    $6,800/Mo

    2 Acre Land Parcel For Lease

    2 acre land parcel for ground lease in Windsor Mill.

    Windsor Mill, MD 21244
    View details
    Commercial Land in Summit City
    $2,300/Mo

    Commercial Land in Summit City

    Commercial land available for rent in Summit City, New Jersey.

    789 Springfield Ave, Summit, NJ 07901
    View details
    Customizable Commercial Space for Lease
    $3,000/Mo

    Customizable Commercial Space for Lease

    Flexible commercial space suitable for various business types.

    1228 Springfield Ave, Irvington, NJ 7111
    View details
    Commercial Land at Major Intersection
    Contact for pricing

    Commercial Land at Major Intersection

    8 acres of commercial land for ground lease.

    12640 Lord Fairfax Hwy, Boyce, VA 22620
    View details

    Downingtown, PA Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Downingtown, PA with 14 listings featured on our commercial real estate exchange. The current inventory includes 14,368 square feet of properties with an estimated lease value of $37 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Downingtown, PA begin at $18 SF/Yr, with an average of $18 SF/Yr and extend to $19 SF/Yr.
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    Most Searched ZIP Codes in Downingtown, PA

    • 19335
    • 19372

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