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    Downingtown, PA Commercial Real Estate for Lease

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    Philadelphia, PA Pittsburgh, PA Allentown, PA
    22 results
    Downingtown Commercial Space For Rent
    $6,000 /Mo

    Downingtown Commercial Space For Rent

    45 W LANCASTER Avenue, Downingtown, PA 19335

    Versatile commercial property in Downingtown, ideal for various businesses.

    • Prime location in Downingtown, near Exton, Chester Springs, West Chester, and Malvern.
    • Flexible zoning suitable for retail, medical, daycare, salon/spa, health club, banquet facility, or warehouse.
    • Expansive open floor plan with HIGH 14' CEILINGS.
    • Approximately 29 parking spaces available.
    • Equipped with TWO LOADING DOCKS and 3‑phase electric.
    Updated: Aug 28, 2025
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    Downingtown Commercial Property For Rent
    $6,000 /Mo

    Downingtown Commercial Property For Rent

    45 W Lancaster Ave, Downingtown, PA 19335

    Versatile commercial property suitable for retail, medical, daycare, or warehouse.

    • Prime location in Downingtown, near Exton, Chester Springs, West Chester, and Malvern.
    • Versatile commercial property with flexible zoning suitable for retail, medical, daycare, salon/spa, health club, banquet facility, or warehouse use.
    • Expansive open floor plan with soaring 14’ ceilings.
    • Approximately 29 parking spaces.
    • Equipped with two loading docks, 3‑phase electric, and HVAC.
    Updated: Aug 28, 2025
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    Downingtown Commercial Space for Lease
    $12,000 /Mo
    7,500 SF

    Downingtown Commercial Space for Lease

    7,500 SF commercial space suitable for various ventures.

    20 COUNTRY CLUB DRIVE, Downingtown, PA 19335
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    Medical Office Space For Lease
    Contact for pricing
    10,500 SF

    Medical Office Space For Lease

    Medical office space available across from Thorndale Station.

    3025 Zinn Road, Thorndale, PA 19372
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    Furnished Office Sublease in Downingtown
    $650 /Mo

    Furnished Office Sublease in Downingtown

    Fully furnished office space with utilities included in Downingtown, PA.

    4333 LINCOLN Highway E, Downingtown, PA 19335
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    Restaurant and Junior Anchor Space
    Contact for pricing
    10,800 SF

    Restaurant and Junior Anchor Space

    Restaurant and retail spaces available in Downingtown, Pennsylvania.

    10-70 Quarry Rd, Downingtown, PA
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    Downingtown Warehouse/Flex Sublease Opportunity
    $8 SF/Yr
    21,000 SF

    Downingtown Warehouse/Flex Sublease Opportunity

    Warehouse/Flex space available for sublease, featuring loading docks and height.

    419 Boot Rd, Downingtown, PA
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    Retail Space on Lincoln Highway
    Contact for pricing
    1,200 SF

    Retail Space on Lincoln Highway

    Retail space with high visibility on Lincoln Highway.

    4301-4339 W Lincoln Hwy, Downingtown, PA
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    Medical Office Space Available
    Contact for pricing
    10,500 SF

    Medical Office Space Available

    Medical office space for lease near Thorndale Station.

    Downingtown, PA 19372
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    New Flex Space For Rent
    Contact for pricing
    17,130 SF

    New Flex Space For Rent

    17,130 SF flex space under construction with signalized access.

    415 Brandywine Ave, Downingtown, PA
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    Downingtown Office Space Available
    $18 SF/Yr
    6,868 SF

    Downingtown Office Space Available

    Office space featuring private offices and a large conference room.

    350 Marshallton Thorndale Rd, Downingtown, PA
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    Downingtown Retail Anchor Opportunity
    Contact for pricing
    28,258 SF

    Downingtown Retail Anchor Opportunity

    Retail space available in Downingtown near major retailers.

    845-965 E Lancaster Ave, Downingtown, PA
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    Restaurant and Junior Anchor Space
    Contact for pricing
    5,653 SF

    Restaurant and Junior Anchor Space

    Restaurant and junior anchor space available in Downingtown, PA.

    26 Quarry Rd, Downingtown, PA
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    Retail Space Near Transportation Hub
    $9 SF/Yr
    2,800 SF

    Retail Space Near Transportation Hub

    Retail space near major routes and train station.

    41-65 N Bailey Rd, Thorndale, PA
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    Prime Commercial Space For Lease
    Contact for pricing

    Prime Commercial Space For Lease

    Office, retail, or restaurant space available in Downingtown, PA.

    180 Park Rd, Downingtown, PA
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    Downingtown Office Space For Rent
    Contact for pricing
    3,800 SF

    Downingtown Office Space For Rent

    Office space in affluent area near Eagleview Corporate Center.

    164 Park Rd, Downingtown, PA
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    Downingtown Office Building with Drive-Thru
    Contact for pricing
    2,550 SF

    Downingtown Office Building with Drive-Thru

    Freestanding office building with drive-thru and dedicated parking.

    1201 E Lancaster Ave, Downingtown, PA
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    Redeveloped Downingtown Office and Retail
    Contact for pricing
    103,880 SF

    Redeveloped Downingtown Office and Retail

    Class A office and retail space in Downingtown, Pennsylvania.

    150 E Pennsylvania Ave, Downingtown, PA 19335
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    Downingtown Retail Space For Rent
    Contact for pricing

    Downingtown Retail Space For Rent

    Retail space in a premier mixed-use transit-oriented community.

    200 River Station Blvd, Downingtown, PA 19335
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    Scalable Medical Office Building
    Contact for pricing
    65,000 SF

    Scalable Medical Office Building

    Medical office building in Downingtown, PA, ranging from 30,000-65,000 SF.

    Route 322 and Boot Rd, Downingtown, PA 19335
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    Mixed-Use Complex on Lancaster Avenue
    Contact for pricing

    Mixed-Use Complex on Lancaster Avenue

    Mixed-use property featuring retail, office, and distribution spaces.

    520 E Lancaster Ave, Downingtown, PA 19335
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    Active Shopping Center Retail Spaces
    Contact for pricing
    1,575 SF

    Active Shopping Center Retail Spaces

    Retail spaces available in active shopping center anchored by Acme.

    3923 Lincoln Hwy, Downingtown, PA 19335
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    Based on your search, we've compiled 36 Potential Opportunities for your consideration. Besides 22 Active listings in Downingtown, PA, we suggest exploring alternatives. Similar 14 Properties for Sales.

    Explore Similar Spaces for Sale in Downingtown, PA

    Consider Similar Space for Sale. We found 14 Spaces matching your search parameters.

    Downingtown Land For Sale
    $450,000
    5.30 Acres

    Downingtown Land For Sale

    5.3 acre flat land parcel zoned for residential or livestock.

    275 CORNER KETCH LYNDELL Road, Downingtown, PA 19335
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    Turnkey Smoothie Shop Opportunity
    $50,000

    Turnkey Smoothie Shop Opportunity

    Fully equipped smoothie shop for sale in Thornsdale, Pennsylvania.

    3411 LINCOLN Highway, Thorndale, PA 19372
    View details

    Downingtown, PA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Downingtown, PA with 22 listings featured on our commercial real estate exchange. The current inventory includes 1,877,447,996 square feet of properties with an estimated lease value of $21 SF/Yr.

    Estimated lease rates for Commercial real estate in Downingtown, PA begin at $3 SF/Yr, with an average of $7 SF/Yr and extend to $9 SF/Yr.
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    Most Searched ZIP Codes in Downingtown, PA

    • 19335
    • 19372

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