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    Portsmouth, NH Office Properties & Spaces for Lease

    65 results
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    Versatile Commercial Space on Lafayette Road
    Contact for pricing
    174,240 SF

    Versatile Commercial Space on Lafayette Road

    750 Lafayette Rd, Portsmouth, NH 03801

    Adaptable space suitable for medical, retail, restaurant, or office use.

    • High‑traffic location on Lafayette Rd (Route 1) at a lighted intersection.
    • Adaptable space suitable for medical, retail, restaurant, or office use.
    • Existing infrastructure for medical/dental use, including exam rooms with water.
    • Private and public bathrooms already in place.
    • Potential to connect with adjacent unit for up to 5,650+/- SqFt with two retail frontages.
    Last Update: Jul 11
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    Prime Portsmouth Commercial Space Available
    Contact for pricing
    174,240 SF

    Prime Portsmouth Commercial Space Available

    750 Lafayette Rd, Portsmouth, NH 03801

    High-traffic location suitable for retail, medical, restaurant, or office use.

    • High‑traffic location at a lighted intersection on Lafayette Rd (Route 1).
    • Versatile space suitable for retail, medical, restaurant/cafe, or office use.
    • 2,050 SqFt first‑floor space available now.
    • Ample on‑site parking with spaces directly in front of the building.
    • Potential to connect to adjoining Suite 103.
    Last Update: Sep 22
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    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    Versatile office space in Portsmouth, accessible from city or bypass.
    500 Maplewood Ave, Portsmouth, NH 03801
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    Prime Portsmouth Commercial Space Available
    Contact for pricing
    4,792 SF

    Prime Portsmouth Commercial Space Available

    1,470 SF office/retail space in high-traffic Portsmouth location.
    1290 Woodbury Ave, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant downtown location.
    10 Vaughan St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Space Available
    Contact for pricing

    Downtown Portsmouth Office Space Available

    Move-in-ready office suites in a vibrant, walkable downtown location.
    10 Vaughan St, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suites Available
    Contact for pricing

    Downtown Portsmouth Office Suites Available

    Move-in-ready office suites in a vibrant downtown location.
    10 Vaughan St, Portsmouth, NH 03801
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    Portsmouth Office Building For Lease
    Contact for pricing

    Portsmouth Office Building For Lease

    Stand-alone Portsmouth office building with great visibility and signage.
    3201 Lafayette Rd, Portsmouth, NH 03801
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    Portsmouth Professional Office Space Available
    Contact for pricing
    1,500 SF

    Portsmouth Professional Office Space Available

    Individual offices for health practitioners, flexible lease terms, utilities included.
    4 Greenleaf Woods Dr, Portsmouth, NH 03801
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    Portsmouth Office Space For Lease
    Contact for pricing
    48,787 SF

    Portsmouth Office Space For Lease

    Versatile office space in Portsmouth, accessible from city or bypass.
    500 Mapplewood Ave, Portsmouth, NH 03801
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    Downtown Portsmouth Office For Lease
    Contact for pricing

    Downtown Portsmouth Office For Lease

    Single office in downtown Portsmouth with utilities included. Available 2025.
    33 Deer St, Portsmouth, NH 03801
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    Portsmouth Medical Office Space
    $19 SF/Yr
    55,200 SF

    Portsmouth Medical Office Space

    Prime Medical Suites, I-95 Access
    330 Borthwick Ave, Portsmouth, NH 03801
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    Portsmouth Office Space For Lease
    $10 SF/Yr
    8,202 SF

    Portsmouth Office Space For Lease

    8,202 SF Office, Prime Location
    500 Maplewood Ave, Portsmouth, NH 03801
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    Vaughan Mall Office Suites
    $18 SF/Yr
    38,745 SF

    Vaughan Mall Office Suites

    Portsmouth, NH Office Space Available
    10 Vaughan Mall, Portsmouth, NH 03801
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    Historic Portsmouth Office Building
    $30 SF/Yr
    4,928 SF

    Historic Portsmouth Office Building

    Spacious Office Space Available, Prime Location
    110 Chapel St, Portsmouth, NH 03801
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    Portsmouth Office/Storage Space Available
    $14 SF/Yr
    62,322 SF

    Portsmouth Office/Storage Space Available

    900 SF heated space, prime Portsmouth location.
    300 Constitution Ave, Portsmouth, NH 03801
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    Prime Pease Tradeport Office Space
    $17 SF/Yr
    14,800 SF

    Prime Pease Tradeport Office Space

    Modern Executive Suites, 14,800 SF Available
    183 International Dr, Portsmouth, NH 03801
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    Portsmouth Office Suites for Lease
    $23 SF/Yr
    58,347 SF

    Portsmouth Office Suites for Lease

    Affordable NH Office Space, 120-204 SF
    170 West Rd, Portsmouth, NH 03801
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    Portsmouth Executive Office Space
    $28 SF/Yr
    47,745 SF

    Portsmouth Executive Office Space

    Prime Portsmouth Office, Flexible Suites Available
    100 Borthwick Ave, Portsmouth, NH 03801
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    Class A Office Space for Lease
    $12 SF/Yr
    62,322 SF

    Class A Office Space for Lease

    Modern, 11,412 SF Executive Office Suite
    300 Constitution Ave, Portsmouth, NH 03801
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    Prime Portsmouth Medical Office Space
    $38 SF/Yr
    52,000 SF

    Prime Portsmouth Medical Office Space

    Class A Medical Office Suites Available Now
    360 Corporate Dr, Portsmouth, NH 03801
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    Downtown Portsmouth Office Suite
    $29 SF/Yr
    22,148 SF

    Downtown Portsmouth Office Suite

    1600 SF Office, Prime Location
    126 Daniel St, Portsmouth, NH 03801
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    Prime Portsmouth Office Space
    $29 SF/Yr
    57,455 SF

    Prime Portsmouth Office Space

    Class A Executive Suites Available
    100 Market St, Portsmouth, NH 03801
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    Modern Office Space for Lease
    $12 SF/Yr
    26,512 SF

    Modern Office Space for Lease

    2,875 SF Office Suite in Rockingham County
    755 Banfield Rd, Portsmouth, NH 03801
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    Portsmouth, NH Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Portsmouth, NH with 84 listings featured on our commercial real estate exchange. The current inventory includes 29,854,673,640 square feet of properties with an estimated lease value of $865 /Mo.

    Estimated lease rates for Office Properties & Spaces in Portsmouth, NH begin at $10 SF/Yr, with an average of $22 SF/Yr and extend to $85 SF/Yr.
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    Browse Office Properties & Spaces for Lease Near Portsmouth, NH

    Popular Searches in Portsmouth, NH

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    Most Searched ZIP Codes in Portsmouth, NH

    • 03801

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