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    Saint Louis, MO Office Buildings for Lease

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    Louis, MO Kansas City, MO Springfield, MO
    76 results
    Commercial Building in High-Traffic Area
    $13 SF/Yr
    4,900 SF

    Commercial Building in High-Traffic Area

    1434 Chambers Road, St, Louis, MO 63135

    4,900 SF commercial building suitable for retail or office use.

    • High‑traffic location with excellent visibility.
    • Large 4,900 sq ft commercial building on a half‑acre lot with ample parking.
    • Zoned C‑1 for General Commercial, suitable for various uses (Retail, Professional Services, Offices, Call Center).
    • Building consists of 2 retail spaces with separate entrances.
    • Main floor: large entry area, 6 offices, 1 bath, large storage room.
    Updated: Oct 6, 2025
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    Class B Office Building
    $20 SF/Yr
    51,545 SF

    Class B Office Building

    Saint Louis, MO 63141

    Class B office building with renovated common areas and covered parking.

    • Recently renovated high‑finish common areas create a modern and professional environment.
    • State‑of‑the‑art building systems ensure efficient and reliable operations.
    • Covered parking provides convenience and protection for tenants and visitors.
    • Suites can be customized to meet specific tenant needs and preferences.
    • Less than one mile from I‑270 access, offering excellent regional connectivity.
    Updated: Jan 26
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    Mixed-Use Center Office Space
    Contact for pricing
    15,000 SF

    Mixed-Use Center Office Space

    Office space available in mixed-use lifestyle center with amenities.

    1114 S Brentwood Blvd, Saint Louis, MO 63117
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    Luxury Clayton Mid-Rise Office Building
    $29 SF/Yr
    7,033 SF

    Luxury Clayton Mid-Rise Office Building

    Luxury office building in Clayton, close to amenities and courthouse.

    7800 Forsyth Blvd, Saint Louis, MO
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    Class A Office Building
    $17 SF/Yr
    20,000 SF

    Class A Office Building

    Well-maintained office building with easy access to major highways.

    Saint Louis, MO 63123
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    Renovated Office Building Investment Opportunity
    $18 SF/Yr
    2,236 SF

    Renovated Office Building Investment Opportunity

    Fully occupied, renovated 2-unit office building in Richmond Heights.

    1530 S Big Bend Blvd, Saint Louis, MO
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    Sunset Hills Office Space Available
    Contact for pricing

    Sunset Hills Office Space Available

    Office space for lease with interstate visibility and access.

    9735 Landmark Parkway, Saint Louis, MO 63127
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    Creve Coeur Office Building
    $24 SF/Yr
    32,461 SF

    Creve Coeur Office Building

    Office building in thriving business district with convenient amenities.

    Saint Louis, MO 63141
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    Class B Office Building For Rent
    $18 SF/Yr
    72,669 SF

    Class B Office Building For Rent

    Class B office building with updated common areas and ample parking.

    Saint Louis, MO 63141
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    Class A Office Near Park
    $28 SF/Yr
    5,744 SF

    Class A Office Near Park

    Modern office building near Forest Park with skyline views.

    Saint Louis, MO 63110
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    Westport Office Building for Rent
    $19 SF/Yr
    14,024 SF

    Westport Office Building for Rent

    First-class office building in Westport with recent renovations.

    Saint Louis, MO
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    Creve Coeur Class B Office
    $22 SF/Yr
    71,805 SF

    Creve Coeur Class B Office

    71,805 SF Class B office building near amenities.

    Saint Louis, MO 63141
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    500,000 SF Class A Workspace
    Contact for pricing
    500,000 SF

    500,000 SF Class A Workspace

    Class A workspace in downtown's Gateway South district.

    760 South 2nd Street, St., Louis, MO 63102
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    Suburban Office Building Near I-270
    $19 SF/Yr
    42,498 SF

    Suburban Office Building Near I-270

    Three-story office building with suites available for lease.

    Saint Louis, MO 63122
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    Class A Office Downtown St. Louis
    $18 SF/Yr
    4,350 SF

    Class A Office Downtown St. Louis

    Premier office building with modern finishes and skyline views.

    Saint Louis, MO
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    Freestanding Office Building For Sale
    $13 SF/Yr
    1,856 SF

    Freestanding Office Building For Sale

    Versatile office building in vibrant Maplewood/Richmond Heights submarket.

    Saint Louis, MO
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    94,000 SF Office Building
    Contact for pricing
    94,000 SF

    94,000 SF Office Building

    Office building with cafeteria, fitness center, and conference center.

    11720 Borman Dr, Saint Louis, MO
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    Premier Suburban Office Campus
    $22 SF/Yr
    3,063 SF

    Premier Suburban Office Campus

    Multi-tenant office portfolio in desirable Webster Groves neighborhood.

    Saint Louis, MO
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    Medical/Office Investment Opportunity
    Contact for pricing
    16,200 SF

    Medical/Office Investment Opportunity

    Medical/Office building for sale in desirable West County submarket.

    Saint Louis, MO
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    Historic Office Building in Downtown
    $12 SF/Yr
    4,610 SF

    Historic Office Building in Downtown

    Prominent 11-story office building with amenities in downtown St. Louis.

    319 N 4th St , St, Louis, MO
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    Renovated Office/Retail Building For Rent
    $12 SF/Yr
    12,600 SF

    Renovated Office/Retail Building For Rent

    Meticulously renovated office/retail building with exposed brick and timber.

    Saint Louis, MO
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    St. Louis Office Building ForRent
    $18 SF/Yr
    13,270 SF

    St. Louis Office Building ForRent

    Office building in the heart of St. Louis for rent.

    Saint Louis, MO
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    Modern Office Space Available
    Contact for pricing
    45,000 SF

    Modern Office Space Available

    Renovated office building with convenient access to amenities and transportation.

    900 N Tucker Blvd, Saint Louis, MO
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    Class A Office Space Available
    $23 SF/Yr
    3,068 SF

    Class A Office Space Available

    Premier office building in Creve Coeur with lake views.

    Saint Louis, MO
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    Saint Louis, MO Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in Saint Louis, MO with 76 listings featured on our commercial real estate exchange. The current inventory includes 4,137,982,200 square feet of properties with an estimated lease value of $204 SF/Yr.

    Estimated lease rates for Office buildings in Saint Louis, MO begin at $12 SF/Yr, with an average of $18 SF/Yr and extend to $29 SF/Yr.
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    Most Searched ZIP Codes in Saint Louis, MO

    • 63141
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    • 63127
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