Saint Louis, MO Office Buildings for Sale

List

Map

Denver, CO Defiance, MO East St Louis, IL Cahokia, IL Sauget, IL Madison, IL Granite City, IL Alorton, IL

55 properties

Sort:

Updated: Dec 8, 2025

Mixed-Use Office Building with Residential

8227 Gravois Road, St, Louis, MO 63123

$325,000

4,800 sqft 0.75 AC lot

2,400 SF main‑floor office space leased to an accounting firm
2,400 SF second‑floor residential living space with two fireplaces, in need of renovations
30 parking spaces included
Separate 450 SF building with two‑car garage and additional office space
0.75‑acre corner lot on a high‑traffic corridor in Affton

View details

Updated: Jul 2

Brick Office Building

8301 Gravois Road, St, Louis, MO 63123

$1,250,000

2.01 AC lot

19,473 square feet of building space
Approximately 87,556 square foot lot for parking, storage, or expansion
Built in 1965
Brick construction
Forced‑air natural gas heating

View details

Historic Office Building

12 N Newstead Avenue, St, Louis, MO 63108

$975,000

0.56 AC lot

Turn-of-the-century former police station offers redevelopment upside with eligible historic tax credits and included parking lot.

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Two-Story Office Building

2838 Meramec St, Saint Louis, MO 63118

$425,000

12,138 sqft 0.54 AC lot

Historic masonry property with flexible interior areas, private rooms, and on-site parking and service access.

View details

Brick Office Building with Gated Parking

1470 S Vandeventer Avenue, St, Louis, MO 63110

$1,650,000

0.98 AC lot

Brick office building with separable suites across two floors and gated parking with 48 spaces.

View details

Five-Office Professional Building

2012 Woodson Road, St, Louis, MO 63114

$455,000

0.30 AC lot

Professional office building with five private offices, reception area, kitchenette, ADA-compliant restroom, and parking lot access.

View details

Two-Story Retail Building

1907 Locust Street, St, Louis, MO 63103

$300,000

5,040 sqft 0.10 AC lot

Two-story brick building built in 1925 with central air and forced-air heat near the CityPark MLS stadium area.

View details

Vacant Mixed-Use Corner Properties

4400 Laclede Ave, Saint Louis, MO 63108

$995,000

11,610 sqft

Two adjacent vacant buildings offer multiple finished floors and retail/office space at a signalized corner.

View details

Two-Story Live-Work Office Building

4073 S Grand Boulevard, St, Louis, MO 63118

$240,000

0.04 AC lot

Two-story commercial building with office space, a full basement, and detached alley-access garage on South Grand Boulevard.

View details

Ranch-Style Office Building

3827 SW Gustine Avenue, St, Louis, MO 63116

$225,000

Classic ranch-style office with about five private offices, a conference room, and flexible common areas.

View details

Office Building with Elevator

11116 S Towne Square - For Sale Saint, Louis, MO 63123

$2,100,000

20,000 sqft 1.00 AC lot

Flexible office layout with a lobby, elevator, surface parking, and access near major regional highways.

View details

Two-Story Live-Work Office Building

4073 S Grand Blvd, Saint Louis, MO 63118

$240,000

3,100 sqft

Two-story commercial building includes a full basement and detached, alley-access garage for flexible live-work or office use.

View details

Two-Level Office Building with Separate Entrances

717 Union Rd, Saint Louis, MO 63123

$319,900

2,740 sqft

Two-level office building previously used as a medical facility, with separate entrances for each level and rear private parking.

View details

St. Louis Office Building For Sale

1210 South 8th Street, St., Louis, MO 63104

$575,000

14,938 sqft

Office building with 14,938 square feet of space.

View details

Freestanding Office in South County

Saint Louis, MO 63129

$160,000

1,856 sqft

1,856 SF office building with walk-out basement and kitchen.

View details

Versatile Commercial Building

3836 Aldine Ave, Saint Louis, MO 63113

$175,900

9,000 sqft

Large commercial building with a flexible interior layout suitable for retail or office use near transit corridors.

View details

Historic Office Building with Gated Parking

308 N 21st St, St., Louis, MO 63103

Contact for pricing

45,200 sqft 0.80 AC lot

Historic office building and 0.80-acre gated parking lot, totaling approximately 45,200 SF with a separate-entry single-story retail space.

View details

Duplex Style Office/Mixed-Use Building

2350 Chambers Rd, Saint Louis, MO 63136

$52,000

3,500 sqft

Office or mixed-use building with multiple entrances and possibilities.

View details

Class A Office Building

Saint Louis, MO 63141

Contact for pricing

215,564 sqft 10.10 AC lot

Multi-story office property with structured and surface parking, signage exposure, and on-site amenities for tenants.

View details

Office Building with Road Frontage

1001 N Kirkwood Rd, Saint Louis, MO 63122

Contact for pricing

2,976 sqft 1.90 AC lot

A 2,976 sq ft office building on a 1.90-acre site with substantial road frontage and commercial/residential zoning.

View details

Brick Commercial Building with Rear Lot

5960 Dr Martin Luther King Dr, Saint Louis, MO 63112

$199,999

27,000 sqft 0.38 AC lot

Three-story brick masonry building sold AS-IS with a rear lot for parking or deliveries and rehab needed after vandalism.

View details

Town & Country Office Building

Saint Louis, MO 63141

Contact for pricing

214,641 sqft

Office building in Town & Country, Missouri, totaling 214,641 square feet.

View details

Historic Office Building for Conversion

1700 Olive St, Saint Louis, MO 63103

$995,000

Built in 1918, this historic office building offers conversion flexibility in Downtown West.

View details

Creve Coeur Former HQ Property

9990 Old Olive Street Rd, Saint Louis, MO

Contact for pricing

63,030 sqft 3.44 AC lot

High-end office building with divisible floorplates and ample parking.

View details

Saint Louis, MO Office Buildings Market Trends and Statistics

Explore 72 office buildings for sale in Saint Louis, MO, showcased through 55 active listings on our real estate platform. These investment opportunities span a total of 1,409,182 square feet of properties for sale, with an estimated market value of $14,223,959.

Sale prices for office properties in Saint Louis, MO start at $52,000, averaging $568,958, and reaching up to $2,100,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

List

Map

Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Demographics Overview

Population 892K

Population Growth (5Y) -1.7%

Median Household Income $75,419

College Educated 40.3%

High-Yield Neighborhoods for Investment

Identify Saint Louis submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
Saint Louis	$397.1K
Fenton	$600K

Taxes & Financing

Average Loan-to-Value 65.0%

Property Size Breakdown

The majority of commercial real estate listings in Saint Louis fall within the 2,500 to 5,000 square foot range.

Need Help?

Reach out if you need assistance with Realmo tools or have questions about your listings