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    Lady Lake, FL Commercial Real Estate for Lease

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    Miami, FL Jacksonville, FL Orlando, FL
    19 results
    Medical Office in The Villages
    $30 SF/Yr
    4,932 SF

    Medical Office in The Villages

    1400 N US Highway 441, Lady Lake, FL

    Turnkey medical office building on UF Health Spanish Plaines campus.

    • Prime location on UF Health Spanish Plaines Hospital campus in The Villages.
    • Turnkey single‑user medical office building.
    • High visibility on US HWY 441 (41,000 AADT).
    • Abundant parking (5/1,000 ratio) with cross‑access to UF Health hospital.
    • Well‑designed layout: Featuring 10 exam rooms, 3 offices, lab, conference room, and a large waiting area.
    Updated: Nov 10, 2025
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    Medical Office in The Villages
    $30 SF/Yr
    4,932 SF

    Medical Office in The Villages

    1400 U.S. 441, Lady Lake, FL 32159

    Turnkey medical office building on UF Health Spanish Plaines campus.

    • Located on UF Health Spanish Plaines Hospital campus in The Villages.
    • Turnkey single‑user medical office building.
    • High visibility on US HWY 441 (41,000 AADT).
    • Surrounded by other medical practices.
    • Abundant parking plus cross‑access with UF Health hospital.
    Updated: Nov 25, 2025
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    Class A Medical Office Space
    $21 SF/Yr
    2,736 SF

    Class A Medical Office Space

    Medical office space for rent with outpatient surgery center.

    201 W Guava St, Lady Lake, FL
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    Lady Lake Retail Space
    Contact for pricing
    23,856 SF

    Lady Lake Retail Space

    Single tenant retail space available for rent in Lady Lake.

    944 Bichara Blvd, Lady Lake, FL 32159
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    Stand-Alone Commercial Building For Lease
    Contact for pricing
    2,500 SF

    Stand-Alone Commercial Building For Lease

    2,500 SF stand-alone commercial building with high visibility.

    126 US-441, Lady Lake, FL 32159
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    Prime Retail Anchor Space Available
    Contact for pricing

    Prime Retail Anchor Space Available

    18,000 SF retail space in high-traffic Lady Lake center.

    Lady Lake, FL 32159
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    Retail Space Near The Villages
    Contact for pricing
    3,000 SF

    Retail Space Near The Villages

    Retail space located near The Villages, a large retirement community.

    492 N Us, Lady Lake, FL
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    Lady Lake Multi-Use Development Land
    Contact for pricing

    Lady Lake Multi-Use Development Land

    44-acre multi-use development site near The Villages.

    Teague Trl, Lady Lake, FL
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    Lady Lake Development Opportunity
    Contact for pricing

    Lady Lake Development Opportunity

    44-acre multi-use development site in Lady Lake, Florida.

    406 Griffin Ave, Lady Lake, FL
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    Retail Building with Drive-Thru
    Contact for pricing
    4,934 SF

    Retail Building with Drive-Thru

    4,934 SF building with drive-thru on 2.88 acres.

    431 Us Highway 441/27, Lady Lake, FL
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    Retail Space on 3 Acres
    Contact for pricing

    Retail Space on 3 Acres

    Single tenant retail space available for rent on 3 acres.

    431 US-441, Lady Lake, FL 32159
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    Retail Space Near The Villages
    Contact for pricing
    2,600 SF

    Retail Space Near The Villages

    Retail space located near The Villages, a large retirement community.

    508-512 508 US 27 441, Lady Lake, FL
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    Retail Space Near The Villages
    Contact for pricing
    1,488 SF

    Retail Space Near The Villages

    Retail space located near The Villages, a large retirement community.

    482 N Hwy 27 441, Lady Lake, FL
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    Retail Space Near The Villages
    Contact for pricing
    1,397 SF

    Retail Space Near The Villages

    Retail space available near The Villages, a large retirement community.

    546-572 US 27, Lady Lake, FL
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    Retail Space in Lady Lake
    Contact for pricing
    3,600 SF

    Retail Space in Lady Lake

    Retail space available in a busy shopping center.

    670-684 N US Hwy 441, Lady Lake, FL
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    Medical/Professional Office in The Villages
    Contact for pricing
    1,944 SF

    Medical/Professional Office in The Villages

    Upscale medical/professional office space for lease in Lady Lake.

    929 US-441, Lady Lake, FL 32159
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    Retail Space in Lady Lake
    Contact for pricing
    3,400 SF

    Retail Space in Lady Lake

    Retail space available in established shopping center, Lady Lake, FL.

    600-664 N US Hwy 441, Lady Lake, FL
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    Medical Office in Summit Park
    Contact for pricing

    Medical Office in Summit Park

    Finished medical office space near UF Health Hospital and The Villages.

    741 Co Rd 466, Lady Lake, FL 32159
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    High-Visibility Retail/Office Space Available
    Contact for pricing
    4,000 SF

    High-Visibility Retail/Office Space Available

    Newly completed building with high traffic exposure in The Villages.

    13922 US-441, Lady Lake, FL 32159
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    Based on your search, we've compiled 52 Potential Opportunities for your consideration. Besides 19 Active listings in Lady Lake, FL, we suggest exploring alternatives. Similar 33 Properties for Sales.

    Explore Similar Spaces for Sale in Lady Lake, FL

    Consider Similar Space for Sale. We found 33 Spaces matching your search parameters.

    Luxurious Medical Suite in Lady Lake
    $1,300,000
    0.09 Acres

    Luxurious Medical Suite in Lady Lake

    Move-in-ready medical suite with high-end finishes and flexible layout.

    809 County Road 466, Lady Lake, FL 32159
    View details
    Commercial Lot on Highway 441
    $399,999
    0.29 Acres

    Commercial Lot on Highway 441

    Corner commercial lot with high visibility and heavy commercial zoning.

    138 W HERMOSA STREET, Lady Lake, FL 32159
    View details
    Lady Lake Professional Plaza Office
    $640,000
    2,328 SF

    Lady Lake Professional Plaza Office

    Office space in Lady Lake Professional Plaza available for sale.

    918 ROLLING ACRES, Lady Lake, FL 32159
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    Remodeled Mixed-Use Building, Lady Lake
    $199,000
    1,290 SF

    Remodeled Mixed-Use Building, Lady Lake

    Remodeled mixed-use building in Lady Lake, close to The Villages.

    219 W MCCLENDON STREET, Lady Lake, FL 32159
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    Land Investment Opportunity in Lady Lake
    $2,000,000
    158.90 Acres

    Land Investment Opportunity in Lady Lake

    40-acre land parcel ideal for agriculture or future development.

    4401 GRIFFIN VIEW DRIVE, Lady Lake, FL 32159
    View details

    Lady Lake, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Lady Lake, FL with 19 listings featured on our commercial real estate exchange. The current inventory includes 285,492,240 square feet of properties with an estimated lease value of $51 SF/Yr.

    Estimated lease rates for Commercial real estate in Lady Lake, FL begin at $21 SF/Yr, with an average of $25 SF/Yr and extend to $30 SF/Yr.
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