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San Mateo County, CA Office Spaces for Lease

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1,264 properties
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Office Space with Private Offices
Office Space with Private Offices

555 Mission St, San Francisco, CA 94105

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7,585 sqft

Seven private offices, three conference rooms, and a kitchen in a high-end professional services build-out.

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Plug-and-Play Office Building
Plug-and-Play Office Building

333 Middlefield Rd, Menlo Park, CA 94025

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14,123 sqft

Plug-and-play office space available immediately with a sublease term through 8/31/25.

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Corner Office Space with Core Layout
Corner Office Space with Core Layout

180 Montgomery St, San Francisco, CA 94104

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12,991 sqft

Corner office space featuring a center-core design, on-site management, and security system for smaller tenants.

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Research Laboratory Office Building
Research Laboratory Office Building

285 E Grand Ave, South San Francisco, CA 94080

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7,000 sqft

Fully integrated biology, tissue culture, chemistry, and vivarium lab facility with space available starting July 2026.

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Furnished Office Space with Skybridge Access
Furnished Office Space with Skybridge Access

181 Fremont St, San Francisco, CA 94105

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13,937 sqft

Furnished office suite with column-free interiors, floor-to-ceiling windows, and a commercial kitchen/cafeteria.

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Corner Lot Office Suite
Corner Lot Office Suite

180 Montgomery St, San Francisco, CA 94104

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4,624 sqft

Corner-lot office suite with center core design, on-site management, and a security system, suited for smaller tenants.

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Office Building with Renovated Lobby
Office Building with Renovated Lobby

201 Spear St, San Francisco, CA 94105

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16,949 sqft

Office building with completed major lobby renovation, basement parking, and an exclusive tenant lounge.

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LEED Platinum Office Building with Rooftop Garden
LEED Platinum Office Building with Rooftop Garden

1800 Owens St, San Francisco, CA 94158

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22,745 sqft

LEED Platinum office building with rooftop garden, panoramic Bay and City views, and extensive bike parking.

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San Carlos Biotech/Lab Space
San Carlos Biotech/Lab Space

San Carlos, CA 94070

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13,500 sqft 0.65 AC lot

13,500 RSF biotech/lab/pharma/GMP manufacturing space available Spring 2026.

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Historic Two-Office Unit
Historic Two-Office Unit

100 Bush St, San Francisco, CA 94104

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1,337 sqft

Office unit with kitchen, HVAC, operable windows, and access to a recently modernized elevator.

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Office Building with On-Site Parking
Office Building with On-Site Parking

455 Market St, San Francisco, CA 94105

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3,289 sqft

Office building featuring an electronic lobby directory and on-site parking with commuter rail access nearby.

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Retail Arcade with On-Site Parking
Retail Arcade with On-Site Parking

455 Market St, San Francisco, CA 94105

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12,397 sqft

Leased retail arcade building with on-site management, electronic lobby directory, and on-site parking.

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Remodeled Creative Office Suite
Remodeled Creative Office Suite

209 9th St, San Francisco, CA 94103

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4,037 sqft

Newly remodeled open office with new flooring, lighting, kitchen, two conference rooms, and private elevator access.

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Transbay Retail District Retail Space
Transbay Retail District Retail Space

250 Howard Street, #Ground, San Francisco, CA 94105

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High-end retail space in San Francisco's emerging East Cut.

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Office Space with Large Floor Plate
Office Space with Large Floor Plate

1 Market St, San Francisco, CA 94105

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20,531 sqft

Large office floor plate in clean shell condition with expansive bay depths for flexible tenant layout.

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Full-Floor Office Suite
Full-Floor Office Suite

88 Kearny St, San Francisco, CA 94104

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10,399 sqft

Full-floor office suite includes three conference rooms, a kitchen, and a dedicated phone room.

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Retail Space with Glass-Walled Offices
Retail Space with Glass-Walled Offices

3500 Alameda De Las Pulgas, Menlo Park, CA 94025

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3,354 sqft

Front half offers Class A glass-walled offices and conference rooms, with strong street visibility and ample parking access.

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LEED Platinum Office Building
LEED Platinum Office Building

1800 Owens St, San Francisco, CA 94158

Contact for pricing
27,517 sqft

LEED Platinum office building with rooftop garden, skywalk connections, bike parking, and state-of-the-art security.

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Iconic San Francisco Office Building
Iconic San Francisco Office Building

650 California Street, San Francisco, CA 94108

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Prominent office building on California Street, San Francisco.

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Prestigious Office Space Available
Prestigious Office Space Available

417 Montgomery St, San Francisco, CA

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8,588 sqft 0.22 AC lot

Historic office building with travertine and limestone facade.

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Full-Floor Class A Office Space
Full-Floor Class A Office Space

1 California St, San Francisco, CA 94111

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16,802 sqft

Full-floor office in a Class A, newly renovated lobby with on-site parking and 24-hour security.

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Combined Office Suite with Private Offices
Combined Office Suite with Private Offices

22 Battery St, San Francisco, CA 94111

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2,622 sqft

Combined suite offers about 2,622 RSF with a large open area, private offices, reception, and kitchenette.

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Office Building with Brick Facade
Office Building with Brick Facade

180 Howard Street, San Francisco, CA 94105

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Office building featuring a brick facade and solar windows.

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Class A Office Suite with Views
Class A Office Suite with Views

1 California St, San Francisco, CA 94111

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15,958 sqft

Office suite features private offices, multiple conference rooms, and direct transit access.

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