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    San Mateo County, CA Mixed-use Properties for Lease

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    34 properties
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    Ground-Floor Mixed-Use Space
    Updated: Mar 4
    Ground-Floor Mixed-Use Space

    6454 Mission Street, Daly City, CA 94014

    $3,180/Mo
    1,089 sqft 0.07 AC lot
    Vacant 1,089‑square‑foot ground‑floor retail space
    Mixed‑use property on 0.0734 acres
    Located at 6454 Mission Street, Daly City, CA 94014
    Access to San Francisco and Silicon Valley
    Near BART, Caltrain, and bus lines
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    Ground-Floor Mixed-Use Space
    Updated: Jul 27
    Ground-Floor Mixed-Use Space

    724 Valencia Street, San Francisco, CA 94110

    $14,000/Mo
    2,500 sqft
    Approximately 2,500 square feet of ground‑floor commercial space
    Approximately 18‑foot ceilings with four skylights
    Newer 400‑amp electrical service throughout
    Electric aluminum roll‑up door with separate man‑door entry
    ADA‑compliant bathroom and front entry ramp
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    Split-Level Mixed-Use Storefront
    Split-Level Mixed-Use Storefront

    1221 Divisadero Street, San Francisco, CA 94115

    $2,500/Mo

    Recently repainted interior with wood flooring, retail shelving, and full street-facing windows.

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    Historic Mixed-Use Complex on Van Ness
    Historic Mixed-Use Complex on Van Ness

    1000 Van Ness Ave, San Francisco, CA 94109

    Contact for pricing
    164,168 sqft

    Modern mixed-use complex with retail, office, and entertainment spaces.

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    Mixed-Use Building with Roof Decks
    Mixed-Use Building with Roof Decks

    500 E 3rd Ave, San Mateo, CA 94401

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    62,622 sqft

    Five-floor office space over 111 residential units with exterior roof decks and two levels of underground parking.

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    Retail Space in Mixed-Use Community
    Retail Space in Mixed-Use Community

    959 El Camino Real, Millbrae, CA

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    17,210 sqft 1.80 AC lot

    Prime retail space in Millbrae's mixed-use community, available Q1 2027.

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    Retail Space in Rincon Center
    Retail Space in Rincon Center

    121 Spear St, San Francisco, CA

    Contact for pricing
    2,289 sqft 3.46 AC lot

    Premier retail opportunity in San Francisco's South Financial District.

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    Mixed-Use Hospitality and Office Building
    Mixed-Use Hospitality and Office Building

    653-655 Commercial St, San Francisco, CA 94111

    Contact for pricing
    2,160 sqft

    Mixed-use building with a fully equipped bar and restaurant, a nightclub level, and a creative office penthouse with private rooftop deck.

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    Mixed-Use Building with Separate Entrances
    Mixed-Use Building with Separate Entrances

    55 Stockton St, San Francisco, CA 94102

    Contact for pricing
    3,489 sqft

    Completed in June 1988, the building offers separate retail and office entrances and on-site 24-hour security.

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    Renovated Storefront Space
    Renovated Storefront Space

    973 Market Street, San Francisco, CA 94103

    Contact for pricing

    Ground-floor retail space occupies a historic San Francisco building with apartments above and a detailed architectural frontage.

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    Restaurant Space with Redevelopment Potential
    Restaurant Space with Redevelopment Potential

    7440 Mission St, Daly City, CA

    Contact for pricing
    3,900 sqft 0.34 AC lot

    Iconic restaurant space available for lease or redevelopment.

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    LEED Gold Mixed-Use Property
    LEED Gold Mixed-Use Property

    55 9th Street, San Francisco, CA 94103

    Contact for pricing

    Ground-level mixed-use space beneath a residential tower in San Francisco’s mid-Market district.

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    Historic Mixed-Use Complex on Van Ness
    Historic Mixed-Use Complex on Van Ness

    San Francisco, CA 94109

    Contact for pricing
    147,528 sqft

    Modern mixed-use complex with retail, office, theater, and residential spaces.

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    Mixed-Use Building Available For Rent
    Mixed-Use Building Available For Rent

    San Francisco, CA 94103

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    Mixed-use building with flexible floor configurations available for rent.

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    Smart Building Mixed-Use Property with Skybridge
    Smart Building Mixed-Use Property with Skybridge

    345 California St, San Francisco, CA 94104

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    5,579 sqft

    Office floors 3–36 and hotel floors 37–48 in a smart building with a glass-enclosed skybridge.

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    Creative Live/Work Loft Space
    Creative Live/Work Loft Space

    1 Clarence Place - Unit 9, San Francisco, CA 94107

    $68 SF/Yr
    1,950 sqft

    1,950 SF creative live/work loft, ideal for small teams.

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    Union Square Mixed-Use Building
    Union Square Mixed-Use Building

    46-50 Geary Street, San Francisco, CA 94108

    Contact for pricing

    Mixed-use building in Union Square with retail and office space.

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    Historic Mixed-Use Complex
    Historic Mixed-Use Complex

    1000 Van Ness Ave, San Francisco, CA 94109

    Contact for pricing
    133,000 sqft

    Modern mixed-use complex with retail, office, and entertainment spaces.

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    111 Pine Ave
    111 Pine Ave

    111 Pine Ave, South San Francisco, CA 94080, South San Francisco, CA 94080

    $29.40 SF/Yr

    14,087 - 28,174 SF of Space Available in South San Francisco, CA 94080

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    Modern Retail Space
    Modern Retail Space

    1222 Harrison St, San Francisco, CA 94103

    Contact for pricing
    3,562 sqft

    Storefront setting with transit, bike, auto, and pedestrian accessibility, plus limited on-site parking.

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    Mixed-Use Building with Separate Access
    Mixed-Use Building with Separate Access

    1201 Main St, Redwood City, CA 94063

    Contact for pricing
    28,882 sqft

    Standalone mixed-use building with separate office and residential access, plus dedicated parking and bike storage.

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    Union Square Mixed-Use Retail Space
    Union Square Mixed-Use Retail Space

    55 Stockton St, San Francisco, CA

    Contact for pricing
    3,164 sqft 0.35 AC lot

    Retail space in a mixed-use building in Union Square.

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    Mixed-Use Building with Separate Entrances
    Mixed-Use Building with Separate Entrances

    1201 Main St, Redwood City, CA 94063

    Contact for pricing
    29,190 sqft

    Class A+ office space plus 28 apartment units with separate access and dedicated multi-level parking.

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    Downtown Mixed-Use Office Building
    Downtown Mixed-Use Office Building

    1201 Main St, Redwood City, CA 94063

    Contact for pricing
    26,037 sqft

    Class A+ office space with separate access to 28 apartments, plus dedicated parking across two levels.

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    San Mateo County, CA Mixed-use properties Market Trends and Statistics

    Explore Mixed-use properties leasing options in San Mateo County, CA with 34 listings featured on our commercial real estate exchange. The current inventory includes 731,334 square feet of properties with an estimated lease value of $199.64 SF/Yr.

    Estimated lease rates for Mixed-use properties in San Mateo County, CA begin at $29.40 SF/Yr, with an average of $49.91 SF/Yr and extend to $68 SF/Yr.
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