Mixed-Use

San Mateo County, CA Mixed-use Properties for Lease

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Found 44 mixed-use property listings for lease in San Mateo County, CA, averaging $41/SF/YR. Use lease type data to compare options faster.
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Mixed-Use Property with Winery
Updated: Jan 22
Mixed-Use Property with Winery

Half Moon Bay, CA 94019

$15,000/Mo
6,254 sqft 1.01 AC lot
6,254 square feet on 1.006 acres
Currently operating as a winery, tasting room, and event venue
One‑bedroom home used as a short‑term vacation rental
Living and dining rooms with a private bathroom used for gatherings and meetings
Along the Hwy 92 corridor in Half Moon Bay
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Three-Level Mixed-Use Building
Updated: Nov 8
Three-Level Mixed-Use Building

6500 Mission St, Daly City, CA 94014

$7,500/Mo
5,085 sqft
Three‑level mixed‑use property with street, upper, and lower floors
Street level features high ceilings, extensive windows, and a double‑door entrance
Upper floor includes a full kitchen and bathroom
Lower level has a roll‑up door, sink, mechanical area, and side‑gate access
C1 zoning; building dates to 1900
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Mixed-Use Property with Full Kitchen
Mixed-Use Property with Full Kitchen

1-335 S Van Ness Ave, San Francisco, CA 94102

Civic Center
$5,500/Mo
1,687 sqft  Built 1927
Highway access  UMU

Ground-floor commercial space includes a conference room, two bathrooms and substantial storage.

Utilities to site  Recessed lighting  Full kitchen  Conference room
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Mixed-Use Building with Storefront
Mixed-Use Building with Storefront

1122 Sutter Street # A, San Francisco, CA 94109

Tenderloin Heights
$2,100/Mo
693 sqft  Built 1910

Commercial space occupies the ground floor, with residential units on the upper levels.

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Mixed-Use Storefront Property
Mixed-Use Storefront Property

A-1122 Sutter Street, San Francisco, CA 94109

Financial District/South Beach
$2,100/Mo
693 sqft  traditional San Francisco architecture

Commercial space occupies the ground floor beneath residential units in a San Francisco building.

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Sprinklered Flex Space
Sprinklered Flex Space

65 Norfolk, San Francisco, CA 94103

South of Market
$42.40 SF/Yr
920 sqft
Highway access  WMUG

Unit F combines warehouse, office, kitchen, and restroom areas within a modern mixed-use commercial building.

Sprinklered
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Mixed-Use Commercial Suite with Kitchen
Mixed-Use Commercial Suite with Kitchen

335 South Van Ness Avenue # 1, San Francisco, CA 94103

Mission
$5,500/Mo
1,687 sqft  Built 1927
Highway access  UMU

The ground-level space includes a full kitchen, conference room, storage, and two bathrooms, one with a shower.

Recessed lighting  Full kitchen  Conference room  Two bathrooms (one with shower)
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Ground-Floor Mixed-Use Space
Ground-Floor Mixed-Use Space

724 Valencia Street, San Francisco, CA 94110

Mission
$12,000/Mo
2,500 sqft  Built 1921

Open commercial space with upgraded electrical service, skylights, and ADA access.

Sprinklered  Skylights  ADA-compliant bathroom  Front entry ramp
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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

4837-4837 Mission St, San Francisco, CA 94112

Excelsior
$3,480/Mo
Multi-tenant  1,200 sqft  2,808 sqft building  2-story
Road access

Two one-bedroom apartments sit above a vacant ground-floor retail space.

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Ground-Floor Mixed-Use Space
Ground-Floor Mixed-Use Space

67 Haight Street, San Francisco, CA 94102

Hayes Valley
$7,000/Mo
1,650 sqft  Built 1952
Road access  NCT-3

The commercial unit pairs an open plan with a kitchen, storage, and a private restroom.

Hardwood floors  Kitchen  Storage area  Private restroom
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Mixed-Use Property Below Residences
Mixed-Use Property Below Residences

300 3rd St, San Francisco, CA 94107

South of Market
Contact for pricing
900 sqft
Highway access

Retail and office space beneath residential condominiums near the Moscone Center.

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Mixed-Use Retail and Creative Office Portfolio
Mixed-Use Retail and Creative Office Portfolio

165 Post St, San Francisco, CA 94108

Financial District/South Beach
Contact for pricing
8,182 sqft  Built 1908

Two-building portfolio combining ground-floor retail with creative office space above, offered for sale at scale.

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Mixed-Use Building with Retail
Mixed-Use Building with Retail

2670 Geary Blvd, San Francisco, CA 94118

Presidio Heights
Contact for pricing
910 sqft

Two linked towers combine 101 residences with street-level retail and shared amenity spaces.

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Retail Suites at Manzanita Square
Retail Suites at Manzanita Square

1557-1600 Holloway Ave, San Francisco, CA 94132

Oceanview/Merced/Ingleside
Contact for pricing
1,172 sqft

Five retail suites occupy the first two floors of a 170-apartment student housing development.

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Mixed-Use Space with Five Rooms
Mixed-Use Space with Five Rooms

3676 Sacramento Street, San Francisco, CA 94118

Presidio Heights
Contact for pricing
1,600 sqft

Second-floor premises combine five separate rooms, two restrooms, and access to a shared rear patio.

Shared rear patio
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Mixed-Use Building with Storefront
Mixed-Use Building with Storefront

2115 Taraval Street, San Francisco, CA 94116

Sunset/Parkside
$6,150/Mo
Built 1926

NC-2 zoning supports varied neighborhood commercial uses in a mixed-use setting.

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Renovated Storefront Space
Renovated Storefront Space

973 Market St, San Francisco, CA 94103

South of Market
Contact for pricing
1,904 sqft  Renovated 2014

Ground-floor retail space occupies a historic San Francisco building with apartments above and a detailed architectural frontage.

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Flexible Office Building
Flexible Office Building

1 Franklin Pkwy, Bldg 970, San Mateo, CA 94403

Contact for pricing
135–225 people  33,810 sqft
Public transit  Highway access

Office configuration can accommodate either one user or multiple tenants.

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Mixed-Use Building with Separate Entrances
Mixed-Use Building with Separate Entrances

55 Stockton St, San Francisco, CA 94102

Tenderloin East
Contact for pricing
3,489 sqft  Built 1988

Completed in June 1988, the building offers separate retail and office entrances and on-site 24-hour security.

Life-safety systems  24-hour security  Energy management system  Terraces
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Historic Mixed-Use Complex on Van Ness
Historic Mixed-Use Complex on Van Ness

1000 Van Ness Ave, San Francisco, CA 94109

Tenderloin
Contact for pricing
164,168 sqft  Built 1920

Modern mixed-use complex with retail, office, and entertainment spaces.

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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

4837 Mission ST 4837, San Francisco, CA 94112

Excelsior
$3,480/Mo
Built 1949

Two apartments sit above a substantial ground-floor commercial area with flexible business-use potential.

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Mixed-Use Retail and Office Space
Mixed-Use Retail and Office Space

3030 Larkin Street #A, San Francisco, CA 94109

Russian Hill
$1,850/Mo
500 sqft  Built 1933

Positioned opposite Ghirardelli Square, this compact space offers a retail and office configuration in Fisherman's Wharf.

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Mixed-Use Office and Residential Building
Mixed-Use Office and Residential Building

500 3rd Avenue, San Mateo, CA 94401

Contact for pricing
198,572 sqft  5-story

Five-floor office space with roof decks, underground parking, and nearby Caltrain service supports office users seeking commuter access.

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Mixed-Use Property with Office Suites
Mixed-Use Property with Office Suites

San Francisco, CA 94115

Japantown
Contact for pricing
279–400 sqft
NCD

Hardwood floors, elevator access and a shared outdoor deck serve the property's retail and office suites.

Hardwood floors  Shared restrooms  Common outdoor deck area
View details

San Mateo County, CA Mixed-use properties Market Trends and Statistics

Explore Mixed-use properties leasing options in San Mateo County, CA with 44 listings featured on our commercial real estate exchange. The current inventory includes 730,754 square feet of properties with an estimated lease value of $496.17.

Estimated lease rates for Mixed-use properties in San Mateo County, CA begin at $17.70 SF/Yr, with an average of $41.35 SF/Yr and extend to $68 SF/Yr.
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