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San Mateo County, CA Office Spaces for Lease

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Office Units Near Life Science Cluster
Office Units Near Life Science Cluster

South San Francisco, CA 94080

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10,208 sqft

Office units with access to restaurants, retail, fitness centers, hotels, marina amenities, public transportation, and nearby residential communities.

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Class A Medical Office Space
Class A Medical Office Space

1720 El Camino Real, Burlingame, CA 94010

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4,897 sqft

Medical office space near Mills-Peninsula Medical Center and public transport.

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Office Suite with Training and Conference Rooms
Office Suite with Training and Conference Rooms

1 Market St, San Francisco, CA 94105

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1,552 sqft

Office suite with large training rooms, multiple conference rooms, phone rooms, kitchens, and a fitness center with showers.

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Second-Generation Office Suite
Second-Generation Office Suite

275 Battery St, San Francisco, CA 94111

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4,291 sqft

Second-generation office suite with abundant natural light, double door elevator access, and multiple private offices and conference rooms.

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Office Space Near Caltrain
Office Space Near Caltrain

South San Francisco, CA 94080

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7,107 sqft

Centrally located office option within the South San Francisco life science cluster, walkable to CalTrain.

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San Mateo Office Space Available
San Mateo Office Space Available

25 E 4th Ave, San Mateo, CA 94401

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5,410 sqft

Office space available for lease in San Mateo, CA.

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Office Suite with Production and Storage
Office Suite with Production and Storage

909 Montgomery St, San Francisco, CA 94133

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8,398 sqft

Office suite with sixteen private offices, a conference room, and large production and storage space plus kitchen and shower.

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Ground Floor Office Suite
Ground Floor Office Suite

2095 Jerrold Ave, San Francisco, CA 94124

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3,173 sqft

Ground floor office suite with an open floor plan, kitchenette, natural light, and two on-site parking spaces.

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Renovated Office Suite with Conference Rooms
Renovated Office Suite with Conference Rooms

372-374 Brannan St, San Francisco, CA 94107

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1,760 sqft

Recently renovated office suite with full HVAC, exposed ductwork, and two conference rooms including a windowed room.

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Flex Space with Office and Warehouse
Flex Space with Office and Warehouse

831-839 Mitten Road, Burlingame, CA 94010

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1,103 sqft

Two-story flex facility with expansive window lines and 24 EV charging stations.

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Flexible Office Building
Flexible Office Building

1 Franklin Pkwy, Bldg 970, San Mateo, CA 94403

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33,810 sqft

Office configuration can accommodate either one user or multiple tenants.

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Office Space Near Caltrain
Office Space Near Caltrain

601 Gateway Blvd, South San Francisco, CA 94080

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2,801 sqft

Office space in the South San Francisco life science cluster with CalTrain access and nearby retail, dining, and hotels.

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Elevator-Served Office Floor
Elevator-Served Office Floor

350 Convention Way, Redwood City, CA 94063

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25,853 sqft

Entire second-floor office space offers a strong window line, private offices, conference rooms, and in-suite restrooms.

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Second-Floor Flex Space Unit
Second-Floor Flex Space Unit

1595 Fairfax Avenue Unit B, San Francisco, CA 94124

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10,110 sqft

Flexible second-floor space in an industrial corridor, zoned for light industrial and trade office uses.

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Bank Building with Ground-Floor Retail
Bank Building with Ground-Floor Retail

1801 Van Ness Ave, San Francisco, CA 94109

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778 sqft

Bank-focused space offering ground-floor retail, two office suites on the third floor, and secure parking with transit access.

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Office Suite with Open Plan
Office Suite with Open Plan

49 Geary St, San Francisco, CA 94108

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13,294 sqft

Office suite features exposed 13-foot ceilings, open layout, and multiple huddle areas with natural light from window lines.

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Sky Blue Penthouse Office Suite
Sky Blue Penthouse Office Suite

1550 Bryant St, San Francisco, CA 94103

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3,999 sqft

Open creative build out includes two conference rooms, an enclosed break room, and a penthouse outdoor deck with catering kitchen.

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Flex Space with Loading Doors
Flex Space with Loading Doors

401 Keith St, San Francisco, CA 94124

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17,483 sqft

Versatile facility combining office, warehouse, and manufacturing functions with substantial loading access.

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Renovated Historic Office Building
Renovated Historic Office Building

114 Sansome St, San Francisco, CA 94104

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5,100 sqft

Historic building fully renovated and retrofitted, with basement storage and close proximity to BART and MUNI transit.

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High-Floor Office with Private Roof Deck
High-Floor Office with Private Roof Deck

100-120 Stockton St, San Francisco, CA 94108

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25,971 sqft

Brand-new high-floor office features a private roof deck, dedicated lobby with signage opportunities, and exclusive shower facilities.

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Street-Level Creative Space
Street-Level Creative Space

1500 20th St, San Francisco, CA 94107

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1,750 sqft

Flexible workspace with private and collaborative rooms, a kitchen, laundry appliances, and a full bathroom with shower.

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Furniture-Included Office Space
Furniture-Included Office Space

989 Market St, San Francisco, CA 94103

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91,110 sqft

Office space with an existing build-out and furniture included, available as single-floor or full-building options.

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Office Condo for Lease
Office Condo for Lease

929 Clay St, San Francisco, CA 94108

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1,320 sqft

Office condo unit available for lease in a high-visibility commercial corridor near transit connections.

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Industrial Flex Suite with Roll-Up Doors
Industrial Flex Suite with Roll-Up Doors

593 Quarry Road, San Carlos, CA 94070

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9,108 sqft

Versatile industrial and flex layout with built-out office space and two roll-up drive-in doors, available July 1, 2026.

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