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Barnstable County, MA Mixed-use Properties for Sale

51 results
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Restaurant Space in Downtown Hyannis
$499,000
2,256 SF

Restaurant Space in Downtown Hyannis

517 Main St, Hyannis, MA 02601

Turnkey restaurant with flexible space in the heart of Hyannis.

  • Prime Downtown Main Street location in Hyannis, close to attractions, ferries, the airport, shopping, and entertainment.
  • Licensed restaurant space with 70 indoor seats and 24 outdoor patio seats.
  • Fully equipped commercial kitchen ready for immediate use.
  • Remodeled second floor with flexible space for storage, office, or a one‑bedroom residential unit.
  • Utilities include natural gas heating, wall unit cooling, and public water/sewer.
Updated: Mar 4
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Harwich Port Live/Work Compound
$925,000
3,358 SF

Harwich Port Live/Work Compound

820 Route 28, Harwich, MA 02646

Unique live/work property in desirable Harwich Port location.

  • Prime Harwich Port location on Route 28 with high visibility.
  • Blend of gallery/retail space (1500 SF +/-) and residential units for live/work or rental income.
  • Includes a one‑bedroom apartment above the retail space.
  • Features a detached one‑bedroom cottage for additional living or rental options.
  • Separate workshop for creative pursuits, storage, or expansion.
Updated: Dec 30, 2025
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Charming Commercial Property in Wellfleet
$1,350,000
3,119 SF

Charming Commercial Property in Wellfleet

Commercial/Residential property with endless potential in the heart of Wellfleet.

20 Bank St, Wellfleet, MA 02667
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Hyannis Commercial Space For Sale
$2,250,000
13,242 SF

Hyannis Commercial Space For Sale

Prime commercial space in downtown Hyannis with diverse tenant mix.

338 Main St, Hyannis, MA 02601
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Turnkey Commercial Building in Orleans
$950,000
1,548 SF

Turnkey Commercial Building in Orleans

Renovated mixed-use building in top location with highway access.

29 West Rd, Orleans, MA 02653
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Mixed-Use Land in Eastham, MA
$600,000
1.14 Acres

Mixed-Use Land in Eastham, MA

1.14 acres of mixed-use land in convenient Eastham location.

20 Oak Rd, Eastham, MA 02642
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West Dennis Mixed-Use Retail Opportunity
Pending
$886,000
4,440 SF

West Dennis Mixed-Use Retail Opportunity

Retail space with residential units in West Dennis, Massachusetts.

467 Main St, West Dennis, MA 02670
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Mixed-Use Acre on Main Street
Pending
$886,000
4,440 SF

Mixed-Use Acre on Main Street

Adaptable mixed-use property with residential and commercial potential on Main Street.

467 Main St, West Dennis, MA 02670
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Mixed-Use Commercial Building in Falmouth
$595,000
2,947 SF

Mixed-Use Commercial Building in Falmouth

Mixed-use building in downtown Falmouth with income potential.

346 Gifford Street Ext, Falmouth, MA 02540
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Main Street Retail and Residence
Pending
$675,000
2,112 SF

Main Street Retail and Residence

Prime Hyannis location with retail space and on-site residence.

547 Main St, Hyannis, MA 02601
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Waterfront Commercial Building in Provincetown
$2,975,000
3,427 SF

Waterfront Commercial Building in Provincetown

Rare opportunity: waterfront commercial building with restaurant and residence.

269 Commercial St, Provincetown, MA 02657
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Orleans Mixed-Use Investment Opportunity
$2,150,000
3,843 SF

Orleans Mixed-Use Investment Opportunity

Three parcels in Orleans Village Center District with mixed-use potential.

88 Route 6A, Orleans, MA 02653
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Downtown Hyannis Mixed-Use Property
$1,285,000
4,032 SF

Downtown Hyannis Mixed-Use Property

Turnkey mixed-use property with buildable lot in downtown Hyannis.

574 Main St, Hyannis, MA 02601
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Rare Provincetown Mixed-Use Opportunity
$1,549,000
3,397 SF

Rare Provincetown Mixed-Use Opportunity

Three condos, including two commercial units and a residential unit.

374 Commercial St, Provincetown, MA 02657
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Harwich Port Mixed-Use Opportunity
Pending
$1,549,000
2,493 SF

Harwich Port Mixed-Use Opportunity

Commercial space with apartment in excellent condition and on-site parking.

515 Route 28, Harwich Port, MA 02646
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Turn-Key Investment in Hyannis, MA
$2,000,000
3,415 SF

Turn-Key Investment in Hyannis, MA

Fully renewed mixed-use property with immediate income potential.

712 Main St, Hyannis, MA 02601
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Mixed-Use Cluster in Provincetown
$4,950,000
5,791 SF

Mixed-Use Cluster in Provincetown

Rare mixed-use property in the heart of Provincetown.

234 Commercial St, Provincetown, MA 02657
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Truro Mixed-Use Landmark Building
$2,000,000
4,032 SF

Truro Mixed-Use Landmark Building

Three-unit commercial building with flexible options and beach rights.

332 Rte 6, Truro, MA 02666
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Prime Commercial Property, Provincetown, MA
$3,950,000
6,148 SF

Prime Commercial Property, Provincetown, MA

Classic commercial property in the heart of Provincetown with bay views.

265 Commercial St, Provincetown, MA 02657
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Chatham Mixed-Use Site For Sale
$546,000

Chatham Mixed-Use Site For Sale

Mixed-use property in Chatham with retail and office/apartment space.

200 Meeting House Rd, South Chatham, MA 02659
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Hyannis Mixed-Use Redevelopment Opportunity
$2,800,000
11,790 SF

Hyannis Mixed-Use Redevelopment Opportunity

Prime commercial property with redevelopment potential in Hyannis, Massachusetts.

453 Main St, Hyannis, MA 02601
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Waterfront Mixed-Use Investment Opportunity
$11,995,000
26,590 SF

Waterfront Mixed-Use Investment Opportunity

Historic Provincetown commercial property with retail, office, and residential spaces.

337 Commercial St, Provincetown, MA 02657
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Orleans Office Building For Sale
$3,900,000
14,341 SF

Orleans Office Building For Sale

14,340 SF office building in the heart of Orleans.

8 Cardinal Ln, Orleans, MA 02653
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Downtown Hyannis Commercial Space
$2,250,000
13,242 SF

Downtown Hyannis Commercial Space

Prime commercial space in thriving downtown Hyannis business district.

338 Main St, Hyannis, MA 02601
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Barnstable County, MA Mixed-Use Properties Investment Opportunities Market Analysis

Explore 1370 mixed-use properties for sale in Barnstable County, MA, showcased through 51 active listings on our real estate platform. These investment opportunities span a total of 40,697,122 square feet of properties for sale, with an estimated market value of $553,158,000.

Sale prices for multi use buildings in Barnstable County, MA start at $60,000, averaging $561,012, and reaching up to $11,995,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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