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    Monroe County, FL Mixed-use Properties for Lease

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    Miami, FL Jacksonville, FL Orlando, FL
    Key West Retail/Office Opportunity
    $4,750/Mo
    1,496 SF

    Key West Retail/Office Opportunity

    607 Fleming Street, Key West, FL 33040

    Mixed-use building in Old Town Key West, near Duval Street.

    • Prime Old Town Key West location, one block from Duval Street.
    • High foot traffic area surrounded by top restaurants and shops.
    • 1496 Sq.ft. of customizable space.
    • Mixed‑use building suitable for retail or office.
    • Street‑level entrance.
    Updated: Nov 12, 2025
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    Stock Island Commercial Space For Rent
    $5,000/Mo
    3,618 SF

    Stock Island Commercial Space For Rent

    6150 2Nd Street, Stock Island, FL 33040

    Corner commercial space with outdoor tiki hut near Key West.

    • Prime corner location just over the bridge from Key West on US Highway 1
    • Large approximately 3,000 SF outdoor tiki hut
    • 618 SF commercial space offering versatile indoor/outdoor business use
    • High‑visibility location across from Wrecker's Cay housing complex and Beach Weekend Marina
    • Excellent traffic exposure
    Updated: Oct 1, 2024
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    Based on your search, we've compiled 38 Potential Opportunities for your consideration. Besides 2 Active listings in Monroe County, FL, we suggest exploring alternatives. Similar 32 Properties for Sales.

    Similar Spaces for Sale in Monroe County, FL

    Consider Similar Space for Sale. We found 32 Spaces matching your search parameters.

    Prime US-1 Mixed-Use Opportunity
    $2,995,000
    6,241 SF

    Prime US-1 Mixed-Use Opportunity

    Mixed-use commercial building with highway frontage in Tavernier, Florida.

    92295 Old State Road, Key Largo, FL 33070
    View details
    New Mixed-Use Development in Key West
    $749,000
    1,491 SF

    New Mixed-Use Development in Key West

    Commercial space in new mixed-use development, completion end of 2026.

    3201 Flagler Avenue, Key West, FL 33040
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    Waterfront Redevelopment Opportunity in Marathon
    $3,549,000
    6,128 SF

    Waterfront Redevelopment Opportunity in Marathon

    Rare waterfront property with redevelopment potential in Marathon, Florida.

    14 125th Street Gulf, Marathon, FL 33050
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    Mixed-Use Commercial Building in Plantation Key
    $1,195,000
    2,244 SF

    Mixed-Use Commercial Building in Plantation Key

    Two-story mixed-use building with highway frontage and income potential.

    88101 Old Highway, Plantation Key, FL 33036
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    Waterfront Lots in Summerland Key
    $899,000
    0.28 Acres

    Waterfront Lots in Summerland Key

    Two contiguous waterfront lots with highway and canal frontage.

    24764 Overseas Highway, Summerland Key, FL 33042
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    Waterfront Redevelopment Opportunity in Marathon
    $3,549,000
    6,128 SF

    Waterfront Redevelopment Opportunity in Marathon

    Rare waterfront property with deep water dockage and highway frontage.

    14 125th Street Gulf, Marathon, FL 33050
    View details
    Stock Island Mixed-Use Opportunity
    $2,200,000
    2,040 SF

    Stock Island Mixed-Use Opportunity

    25,000 SF mixed-use property with redevelopment potential near Key West.

    5580 1st Avenue, Stock Island, FL 33040
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    Waterfront Key West Investment Opportunity
    $4,750,000
    3,788 SF

    Waterfront Key West Investment Opportunity

    Historic Key West property with multi-family and commercial potential.

    901 Eisenhower Drive, Key West, FL 33040
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    Stock Island Commercial Property Available
    $1,950,000
    5,258 SF

    Stock Island Commercial Property Available

    Prime commercial property with mixed-use zoning and income potential.

    5670 Laurel Avenue, Stock Island, FL 33040
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    Key Largo Mixed-Use Property
    $1,790,000
    4,910 SF

    Key Largo Mixed-Use Property

    High-visibility mixed-use property with commercial storefront and residential apartment.

    100636 Overseas Highway, Key Largo, FL 33037
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    Key West Mixed-Use Investment
    $1,625,000
    3,846 SF

    Key West Mixed-Use Investment

    Historic Key West building with commercial and residential units.

    1018 Truman Avenue, Key West, FL 33040
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    Cudjoe Key Commercial Building
    $975,000
    1,120 SF

    Cudjoe Key Commercial Building

    Commercial building with business and residential income potential.

    22814 Overseas Highway, Cudjoe Key, FL 33042
    View details
    Islamorada Mixed-Use Commercial Property
    $4,600,000
    0.21 Acres

    Islamorada Mixed-Use Commercial Property

    Versatile commercial property in Islamorada's established business corridor.

    105 Palm Avenue, Upper Matecumbe Key, Islamorada, FL 33036
    View details
    Restored Mixed-Use Key West Landmark
    $1,375,000
    1,082 SF

    Restored Mixed-Use Key West Landmark

    Historic mixed-use property reimagined for modern living, completed in 2026.

    419 Simonton Street, Key West, FL 33040
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    Key West Mixed-Use Income Property
    $2,999,999
    1,596 SF

    Key West Mixed-Use Income Property

    Fully rented mixed-use property in the heart of Old Town.

    405 Petronia Street, Key West, FL 33040
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    Key West Mixed-Use Investment
    $2,999,999
    1,596 SF

    Key West Mixed-Use Investment

    Fully rented mixed-use property in Old Town Key West.

    405 Petronia Street, Key West, FL 33040
    View details
    Waterfront Redevelopment Opportunity in Marathon, FL
    $3,549,000
    6,128 SF

    Waterfront Redevelopment Opportunity in Marathon, FL

    Rare waterfront property with redevelopment potential and deep water dockage.

    14 125Th Street Gulf, Marathon, FL 33050
    View details
    Waterfront Redevelopment Opportunity in Marathon
    $3,549,000
    6,128 SF

    Waterfront Redevelopment Opportunity in Marathon

    Rare waterfront property with redevelopment potential and deep water dockage.

    14 125Th Street Gulf, Marathon, FL 33050
    View details
    Waterfront Key West Investment Opportunity
    $4,750,000
    3,788 SF

    Waterfront Key West Investment Opportunity

    Historic Key West property with multi-family configuration and commercial zoning.

    901 Eisenhower Drive, Key West, FL 33040
    View details
    Key Largo Commercial Opportunity
    Contact for pricing
    2,400 SF

    Key Largo Commercial Opportunity

    Highway frontage building with upstairs space for lease.

    106600 Overseas Highway, Key Largo, FL 33037
    View details
    Waterfront Redevelopment Opportunity in Marathon
    $3,549,000
    6,128 SF

    Waterfront Redevelopment Opportunity in Marathon

    Rare waterfront property with deep water dockage and highway frontage.

    14 125Th Street Gulf, Marathon, FL 33050
    View details
    Stock Island Commercial Property For Sale
    $1,950,000
    5,258 SF

    Stock Island Commercial Property For Sale

    Commercial property on Stock Island with mixed-use zoning.

    5670 Laurel Ave, Key West, FL 33040
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Atlanta Land for Lease
    $1,850/Mo

    Atlanta Land for Lease

    3-acre commercial land available for lease in Atlanta, GA.

    1057 Constitution Road SW, Atlanta, GA 30315
    View details
    Prime Commercial Acres For Lease
    $6,000/Mo

    Prime Commercial Acres For Lease

    4.12 acres of commercial land for lease in Rainsville, AL.

    4.12 Acres Al Highway 35, Rainsville, AL 35986
    View details
    MidTown Corner Lot For Rent
    Contact for pricing

    MidTown Corner Lot For Rent

    Corner lot with high visibility in growing Nashville neighborhood.

    1811 Charlotte Avenue, Nashville, TN 37203
    View details
    Commercial Land For Rent
    $10,000/Mo

    Commercial Land For Rent

    Commercial land available for rent, high visibility location.

    25699 Interstate 20, Wills Point, TX 75169
    View details

    Monroe County, FL Mixed-use properties Leasing Opportunities Market Analysis

    Explore Mixed-use properties leasing options in Monroe County, FL with 2 listings featured on our commercial real estate exchange. The current inventory includes 5,114 square feet of properties with an estimated lease value of $54 SF/Yr.

    Estimated lease rates for Mixed-use properties in Monroe County, FL begin at $16 SF/Yr, with an average of $27 SF/Yr and extend to $38 SF/Yr.
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    Browse Mixed-use properties for Lease Near Monroe, FL

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