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    Key West, FL
    Mixed-Use

    Key West, FL Mixed-use Properties for Lease

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    Stock Island, FL Big Pine Key, FL Cudjoe Key, FL Summerland Key, FL
    Retail Space with Suite Flexibility
    Updated: Mar 3
    Retail Space with Suite Flexibility

    3201 Flagler Avenue, Key West, FL 33040

    $6,000/Mo
    1,491 sqft
    Approximately 1,491 square feet of retail space
    Two combined units can operate together or be divided into two suites
    White‑box shell delivery supports a tenant‑designed interior
    Under construction with completion scheduled for late 2026
    Mixed‑use project includes 14 residential and 14 commercial units
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    Mixed-Use Building with Open Layout
    Updated: Nov 12, 2025
    Mixed-Use Building with Open Layout

    607 Fleming Street, Key West, FL 33040

    $4,650/Mo
    1,496 sqft
    1,496 SF mixed‑use building constructed in 1933
    Open interior layout with street‑level entry
    Corner location at Fleming Street and Simonton Street
    One block from Duval Street
    Across from Marquesa Restaurant
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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 2 Active listings in Key West, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

    Mixed-use properties for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Mixed-Use Building with Office Floors
    Mixed-Use Building with Office Floors

    299 Alhambra Cir 401, Coral Gables, FL 33134

    $9,450/Mo
    62,327 sqft

    Four office floors sit above ground-floor retail with garage parking and on-site property management.

    View details
    Mixed-Use Property with Office Floors
    Mixed-Use Property with Office Floors

    299 Alhambra Cir Unit 212, Coral Gables, FL 33134

    $4,909/Mo
    62,327 sqft

    Ground-floor retail and flexible office layouts are supported by garage parking and on-site property management.

    View details
    Mixed-Use Project Across From FIU
    Mixed-Use Project Across From FIU

    700 SW 107th Ave, Miami, FL 33174

    Contact for pricing
    15,000 sqft

    Mixed-use project with student housing and direct proximity to Florida International University.

    View details
    Retail Space in Master-Planned Development
    Retail Space in Master-Planned Development

    16000 N Kendall Dr, Miami, FL 33196

    Contact for pricing
    7,000 sqft

    Retail space within a large, established development anchored by a hospital and additional planned residential, medical, and educational uses.

    View details

    Similar Spaces for Sale in Key West, FL

    Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

    Mixed-Use Property with Six Storefronts
    Mixed-Use Property with Six Storefronts

    218 Whitehead Street, Key West, FL 33040

    $4,200,000
    7,755 sqft 0.16 AC lot

    Corner property combines six retail spaces with a three-bedroom, two-bath apartment and separate utility meters.

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    Three-Unit Mixed-Use Property
    Three-Unit Mixed-Use Property

    1200-1206 White Street, Key West, FL 33040

    $1,475,000
    3,380 sqft

    Commercial condominium offering with established occupants, one vacant unit, and flexible office, retail, service, and restaurant use potential.

    View details
    White Box Commercial Suite
    White Box Commercial Suite

    3201 Flagler Avenue, #STE 507, Key West, FL 33040

    $749,000
    1,491 sqft

    Under-construction suite with white-box delivery, ADA access, ample parking, and flexibility to split into two units.

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    Mixed-Use White-Box Space
    Mixed-Use White-Box Space

    3201 Flagler Avenue, Key West, FL 33040

    $749,000
    1,491 sqft 0.71 AC lot

    White-box commercial space allows buyers to configure the interior for professional, medical office, or retail operations.

    View details
    Mixed-Use Corner Property
    Mixed-Use Corner Property

    218 Whitehead Street, Key West, FL 33040

    $4,200,000
    7,755 sqft

    Six retail suites and a three-bedroom apartment combine commercial and residential occupancy in one property.

    View details
    Mixed-Use Property With Restaurant
    Mixed-Use Property With Restaurant

    405 Petronia Street, Key West, FL 33040

    $2,999,999
    1,596 sqft 0.05 AC lot

    Fully leased property combining residential, office, and detached restaurant components in Key West’s Old Town area.

    View details
    Mixed-Use Property with Detached Restaurant
    Mixed-Use Property with Detached Restaurant

    405 Petronia Street, Key West, FL 33040

    $2,999,999
    1,596 sqft 0.05 AC lot

    Fully rented property combines residential, office, and detached restaurant space.

    View details
    Remodeled 150-Seat Restaurant
    Remodeled 150-Seat Restaurant

    532 Margaret Street, Key West, FL 33040

    $2,500,000
    2,490 sqft 0.11 AC lot

    Licensed dining property includes indoor-outdoor seating, a full-service bar, commercial kitchen, and an upstairs one-bedroom apartment.

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    Three-Building Mixed-Use Property
    Three-Building Mixed-Use Property

    5350 Overseas Highway, Key West, FL 33040

    Contact for pricing

    Multi-building commercial property positioned along Overseas Highway in Key West.

    View details

    Key West, FL Mixed-use properties Lease Rates & Market Statistics

    Browse 2 Mixed-use properties for lease in Key West, FL on Realmo, a commercial real estate marketplace serving the Key West area. The current inventory totals 2,987 square feet of properties.

    Asking lease rates for Mixed-use properties in Key West start at $37.30 SF/Yr, average $42.80 SF/Yr, and reach $48.29 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $42.80 SF/Yr is 53% above the Florida state average of $27.92 SF/Yr.

    Key West accounts for 67% of the 3 mixed-use properties currently available across Monroe County, where a nearby market includes Islamorada.

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    Browse Mixed-use properties for Lease Near Key West, FL

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    Most Searched ZIP Codes in Key West, FL

    • 33040

    Featured Key West Real Estate Agencies

    Realmo connects you with licensed Key West CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Berkshire Hathaway Keys Real Estate | Knight & Gardner Realty
    336 Duval St Key West, FL 33040
    Phone: 13052945155
    www.keysrealestate.com
    Truman & Co. Real Estate Services
    1205 Truman Avenue Key West, FL 33040
    Phone: 13052922244
    www.trumanandcompany.com
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