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North Charleston, SC

Medical Space

North Charleston, SC Medical Office Space for Lease

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10 properties

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Full-Floor Medical Office Suite

Updated: Jun 11

Full-Floor Medical Office Suite

4969 Centre Pointe Drive # 100, North Charleston, SC 29418

Contact for pricing

10,363 sqft

Full‑floor medical office suite available January 1, 2027 at 4969 Centre Pointe Drive
Suite 100 offers 10,363 RSF and has expansion potential by an additional 3,000 SF
Expansion allows up to 21,000 SF total for the suite
Offered at a full‑service rate of $36.00 per RSF

Flex Space with Roll-Up Door

Updated: Jun 13

Flex Space with Roll-Up Door

2409 Mall Drive # B, North Charleston, SC 29406

Contact for pricing

8,333 sqft 1.21 AC lot

+/-8,333 SF flex suite inside a +/-20,000 SF building on +/-1.21 acres with ample free parking
Fully conditioned interior with multiple restrooms and high ceilings, supporting office/medical and flexible storage‑style use
Built in 1972; CRD Commercial zoning and roll‑up door (existing or potential modification)
Along a high‑traffic corridor in North Charleston’s established commercial corridor with proximity to major retail and employment centers
Base rent $11.50/SF includes water & electricity; TICAM is approximately $9.00/SF

First-Generation Office and Medical Suites

First-Generation Office and Medical Suites

8471 Dorchester Road, North Charleston, SC 29420

Contact for pricing

6,500 sqft

Flexible, suite-divisible two-story space on a busy commercial corridor with landlord-provided shell build-out.

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Medical Office Suite

Medical Office Suite

3210 Landmark Drive, North Charleston, SC 29418

Contact for pricing

1,880 sqft

Move-in ready OB-GYN medical space with strong visibility, signage, and ample parking for healthcare practices.

End-Cap Office Suite

End-Cap Office Suite

2431 Aviation Avenue # 709, North Charleston, SC 29406

Contact for pricing

6,127 sqft

Professional workspace combines enclosed offices with open-plan area and abundant natural light.

North Charleston Office Space Available

North Charleston Office Space Available

2070 Northbrook Blvd, North Charleston, SC

Contact for pricing

1,664 sqft 6.44 AC lot

Office space for rent in North Rivers Business Center.

Medical Office Condo End Cap

Medical Office Condo End Cap

5401 Netherby Lane Ste 601, North Charleston, SC 29420

Contact for pricing

End cap medical office condo with private offices, conference space, and parking within a professional park.

Updated Freestanding Office Building

Updated Freestanding Office Building

2132 Dorchester Road, North Charleston, SC 29405

Contact for pricing

Updated commercial space includes private offices, a kitchen, restroom, and surface parking.

Medical Office Suite with Exam Rooms

Medical Office Suite with Exam Rooms

2891 Tricom Street Ste B, North Charleston, SC 29406

Contact for pricing

Suite includes reception, two exam rooms/offices, an open work area, and two bathrooms on an NNN basis.

Free-Standing Medical Office Suite

Free-Standing Medical Office Suite

9133 Timber Street Suite A, North Charleston, SC 29406

Contact for pricing

Free-standing medical office suite with reception, offices, bathrooms, and a breakroom for lease on an NNN basis.

Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 10 Active listings in North Charleston, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Class A Medical Office Space

Class A Medical Office Space

85 Springview Ln, Summerville, SC 29485

$18 SF/Yr

Professional suites are available for specialty healthcare practices under NNN lease terms.

Two-Story Freestanding Office Building

Two-Story Freestanding Office Building

2125 Charlie Hall Blvd, Charleston, SC 29414

Contact for pricing

13,113 sqft

Entire first floor is available in a centrally located, medically oriented freestanding office building with ample parking.

Class A Medical Office Suite

Class A Medical Office Suite

5500 Front Street, Summerville, SC 29486

Contact for pricing

3,721 sqft

Second-floor medical office space available with tenant improvement allowance and covered patient drop-off/pick-up area.

West Ashley Medical Office Sublease

West Ashley Medical Office Sublease

2270 Ashley Crossing Ln, Charleston, SC

Contact for pricing

3,746 sqft 8.99 AC lot

3,746 SF medical office space available for immediate sublease.

Similar Spaces for Sale in North Charleston, SC

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

Office Redevelopment Opportunity

Office Redevelopment Opportunity

3841 Rivers Avenue, North Charleston, SC 29405

Contact for pricing

5,161 sqft

Two-building office property with multiple private offices, conference areas, and an X-ray room.

Freestanding Office Building

Freestanding Office Building

4425 Belle Oaks Drive, North Charleston, SC 29405

Contact for pricing

6,793 sqft

The building is presented for office, medical, or flex-type use and includes on-site parking.

Light Industrial Flex Buildings

Light Industrial Flex Buildings

3605 Meeting Street Road, North Charleston, SC 29405

Contact for pricing

7,726 sqft 0.64 AC lot

Two freestanding light industrial buildings total about 7,726 SF on roughly 0.64 acres, zoned M-1 and currently delivered vacant.

Dorchester Road Office Space Available

Dorchester Road Office Space Available

7880-7890 Dorchester Rd, North Charleston, SC

Contact for pricing

6,600 sqft 0.67 AC lot

High-traffic location with flexible spaces for professional uses.

North Charleston Medical Office Building

North Charleston Medical Office Building

3800 Faber Place Drive, North Charleston, SC 29405

Contact for pricing

4,345 sqft

Commercial property suitable for medical or professional office use.

Former Day Care Facility

Former Day Care Facility

1910 Mcmillan Avenue, North Charleston, SC 29405

Contact for pricing

12,895 sqft

Former daycare totaling 12,895 SF, positioned just outside the Navy Yard redevelopment project in North Charleston.

North Charleston, SC Medical Office Space Lease Rates & Market Statistics

Explore 10 Medical Office Space listings for lease in North Charleston, SC on Realmo, a commercial real estate exchange covering the North Charleston area. The current inventory totals 34,867 square feet of properties — an average of ~3,500 SF per listing.

Within Charleston County, most North Charleston medical office space listings are located in and around Charleston, with additional options across the city. Medical Office Space listings make up 12% of the 82 Office Spaces currently for lease in North Charleston. Also worth a look for tenants weighing alternatives: Office Units (64 listings) and Office buildings (12 listings) elsewhere in the North Charleston market.

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