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    North Charleston, SC
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    North Charleston, SC Medical Office Space for Lease

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    North Charleston Office Space Available
    Updated: Oct 29, 2025
    North Charleston Office Space Available

    2070 Northbrook Blvd, North Charleston, SC

    $19 SF/Yr
    1,664 sqft · $2,766/Mo
    High Occupancy Rate (98%) indicating strong tenant demand and income stability
    Diverse Tenant Mix including medical, government, and professional office users
    Presence of well‑known tenants such as MUSC Children's Health Clinic and Roper St. Francis ATI
    Strategic Location with accessibility from Rivers Avenue and Northbrook Blvd
    Includes two buildings totaling 79,611 SF
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    First-Generation Office and Medical Suites
    Updated: Jun 2
    First-Generation Office and Medical Suites

    8471 Dorchester Road, North Charleston, SC 29420

    Contact for pricing
    6,500 sqft
    Two‑story office/medical space built in 2014 with 6,500 total SF (5,000 SF first floor, 1,500 SF second floor).
    Space can be divided into up to 3 suites: two 2,500 SF suites on the first floor and one 1,500 SF suite on the second floor.
    Landlord to provide shell build‑out within builders allowance; interior build‑out to suit tenant.
    Located on the busy Dorchester Rd/Ashley Phosphate Rd corridor (First generation Class A office or medical office space).
    Lease rate listed at $17.75/SF/YR; tenant responsible for its share of property taxes and property insurance.
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    Full-Floor Medical Office Suite
    Full-Floor Medical Office Suite

    4969 Centre Pointe Drive # 100, North Charleston, SC 29418

    Contact for pricing
    10,363 sqft

    Full-floor medical office space at Oaks at Centre Pointe with expansion flexibility for growing practices.

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    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Medical Office Suite
    Medical Office Suite

    3210 Landmark Drive, North Charleston, SC 29418

    Contact for pricing
    1,880 sqft

    Move-in ready OB-GYN medical space with strong visibility, signage, and ample parking for healthcare practices.

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    Former Daycare Near Navy Yard
    Former Daycare Near Navy Yard

    1910 McMillan Avenue, North Charleston, SC 29405

    Contact for pricing
    12,895 sqft

    12,895 SF former daycare near new Navy Yard.

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    North Charleston Office Space Available
    North Charleston Office Space Available

    8700 North Park Boulevard, North Charleston, SC

    Contact for pricing
    903 sqft

    Professional office space for lease in North Charleston, SC.

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    Medical/Professional Office Suite For Rent
    Medical/Professional Office Suite For Rent

    2831 Tricom St, North Charleston, SC

    Contact for pricing
    1,830 sqft

    1,830 SF medical/professional office suite near Trident Hospital Campus.

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    Flex Space with Roll-Up Door
    Flex Space with Roll-Up Door

    2409 Mall Drive # B, North Charleston, SC 29406

    Contact for pricing
    8,333 sqft

    Customizable conditioned flex suite with multiple restrooms, high ceilings, and ample free parking along a high-traffic corridor.

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    Class A Medical Office Space
    Class A Medical Office Space

    4600 Goer Dr, North Charleston, SC

    Contact for pricing
    1,647 sqft

    Premier medical office space near Roper St. Francis Hospital.

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    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 9 Active listings in North Charleston, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    West Ashley Medical Office Sublease
    West Ashley Medical Office Sublease

    2270 Ashley Crossing Ln, Charleston, SC

    $32 SF/Yr
    3,746 sqft · $9,989/Mo

    3,746 SF medical office space available for immediate sublease.

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    Two-Story Freestanding Office Building
    Two-Story Freestanding Office Building

    2125 Charlie Hall Boulevard #First Floor, Charleston, SC 29414

    Contact for pricing

    Entire first floor is available in a centrally located, medically oriented freestanding office building with ample parking.

    View details
    Medical/Professional Office Space Available
    Medical/Professional Office Space Available

    2947 Maybank Hwy, Johns Island, SC

    $30 SF/Yr
    4,211 sqft · $10,527/Mo

    Single-story office space ready for upfits near new developments.

    View details
    Maybank Highway Commercial Space
    Maybank Highway Commercial Space

    Maybank Hwy, Johns Island, SC 29455

    $40 SF/Yr
    58,136 sqft · $193,786/Mo

    New construction with space for medical, office, or retail.

    View details

    Similar Spaces for Sale in North Charleston, SC

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Former Daycare Near Navy Yard
    Former Daycare Near Navy Yard

    1910 McMillan Avenue, North Charleston, SC 29405

    $2,300,000
    12,895 sqft · 0.94 AC lot

    12,895 SF former daycare near new Navy Yard project.

    View details
    Dorchester Road Office Space Available
    Dorchester Road Office Space Available

    7880-7890 Dorchester Rd, North Charleston, SC

    $1,150,000
    6,600 sqft · 0.67 AC lot

    High-traffic location with flexible spaces for professional uses.

    View details
    North Charleston Medical Office Building
    North Charleston Medical Office Building

    3800 Faber Place Drive, North Charleston, SC 29405

    $1,500,000
    4,345 sqft

    Commercial property suitable for medical or professional office use.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    View details
    Prime Commercial Lot For Rent
    Prime Commercial Lot For Rent

    Tift Avenue N, Tifton, GA 31794

    $7,500/Mo

    0.66 acre commercial lot with high visibility.

    View details
    WINTER PARK Land Lease Opportunity
    WINTER PARK Land Lease Opportunity

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792

    $8,500/Mo
    23,056 sqft · $4 SF/Yr

    Commercial land lease opportunity in Winter Park, Florida.

    View details
    Corner Lot on Highway 72
    Corner Lot on Highway 72

    30472 Highway 72, Madison, AL 35756

    $5,000/Mo
    1,875 sqft · $32 SF/Yr

    1.7 acre corner lot zoned for commercial, medical, residential.

    View details

    North Charleston, SC Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in North Charleston, SC with 9 listings featured on our commercial real estate exchange. The current inventory includes 8,044 square feet of properties with an estimated lease value of $113 SF/Yr.

    Estimated lease rates for Medical Office Space in North Charleston, SC begin at $12 SF/Yr, with an average of $22 SF/Yr and extend to $30 SF/Yr.
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    Most Searched ZIP Codes in North Charleston, SC

    • 29420
    • 29418
    • 29405
    • 29406

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